Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Gottlieb (2008)
Title HIV type 2 protease, reverse transcriptase, and envelope viral variation in the PBMC and genital tract of ARV-naive women in Senegal.
Citation ARHR
SelectedGene PR
SelectedSpecies HIV2
SelectedType Clinical
NumIsolates 8
NumPts 4
Host Human

 

Clinical PR Isolates


SubjectIsolatePIsWksPIMajorPIMinorCommonUnusual
MIN1974 MIN1974_CVL-DNA None     E16G, N40S, N41D 
MIN3473 MIN3473_CVL-RNA
Consensus 
None    N55NT, I64IV, E65EK, K70X W6W*, Y14H, V22VA, G39GR, N40S, N68NK, G78GD, R87RG, A92AV 
  MIN3473_CVL-DNA
Consensus 
None    K70R, D79X Y14H, N40S 
  MIN3473_PBMC
Consensus 
None    L23X, L24X, N61ND, E65EK, K70X Y14YH, N40S, V66VAI 
  MIN3473_CVL-DNA
clone: 1_1 
None    K70R Y14H, N40S 
  clone: 2_1 None    K70R Y14H, N40S, D79V 
  MIN3473_PBMC
clone: 31_1 
None    E65K, K70T Y14H, N40S 
  clone: 32_1 None    L24X, K70R Y14H, L23L*S, N40S 
  clone: 33_1 None    E65K, K70T Y14H, N40S, V66I 
  clone: 34_1 None    N61D, K70R N40S, V66A 
  clone: 35_1 None    E65K, K70T Y14H, N40S 
  MIN3473_CVL-RNA
clone: 3875 
None    K70R Y14H, N40S, A92V 
  clone: 3876 None    N55T, K70R Y14H, N40S, G78D 
  clone: 3877 None    E65K, K70T Y14H, V22A, N40S, N68K 
  clone: 3896 None    K70R Y14H, N40S 
  clone: 3897 None    I64V, E65K, K70T Y14H, N40S 
  clone: 3898 None    K70R Y14H, N40S 
  clone: 3899 None    W6*, E65K, K70T Y14H, N40S 
  clone: 3900 None    K70R Y14H, N40S 
  clone: 3908 None    E65K, K70T Y14H, G39R, N40S 
  clone: 3909 None    K70R Y14H, N40S 
  clone: 3923 None    K70R Y14H, N40S, R87G 
  clone: 3924 None     Y14H, N40S 
  MIN3473_CVL-DNA
clone: 3_1 
None    K70R Y14H, N40S 
  MIN3473_PBMC
clone: 40_1 
None    K70R Y14H, N40S 
  MIN3473_CVL-DNA
clone: 4_1 
None    K70R Y14H, N40S 
  clone: 5_1 None    K70R Y14H, N40S 
MIN4199 MIN4199_PBMC
Consensus 
None  I32IV  S43SR, E65Q, K70KR Y14YH, N40S, N41ND, T56TI, M95MK 
  clone: 23_1 None    S43R, E65Q N40S, N41D 
  clone: 26_1 None    E65Q N40S, M95K 
  clone: 3630 None    E65Q, K70R N40S, N41D 
  clone: 3631 None    E65Q, K70R N40S, N41D 
  clone: 3632 None    E65Q, K70R N40S, N41D, T56I 
  clone: 3633 None    E65Q, K70R Y14H, I32V, N40S, N41D 
MIN652 MIN652_CVL-RNA
Consensus 
None    R8RG, Q18QR, A34AT, N41X, I64IV, K69KR, F85FL, T91A T26TI, N40NS, T80TA, A92N 
  MIN652_CVL-DNA
Consensus 
None  I46IT A73AV N40X, N41X, I64IV, K70KR, R72RK, T77TI, T91A A92N 
  MIN652_PBMC
Consensus 
None  I82IT  V33VI, N41K, K60X, I64IV, T91A V10VA, N40S, I75IV, D79DG, A92N 
  clone: 3585 None    N41K, T91A N40S, A92N 
  clone: 3586 None    N41K, T91A N40S, A92N 
  clone: 3587 None  I82T  N41K, T91A N40S, A92N 
  clone: 3588 None    N41K, I64V, T91A N40S, A92N 
  clone: 3589 None    N41K, K60X, T91A N40S, A92N 
  MIN652_CVL-DNA
clone: 3590 
None    N41K, T91A N40S, A92N 
  MIN652_PBMC
clone: 3592 
None    V33I, N41K, T91A N40S, A92N 
  clone: 3593 None    N41K, I64V, T91A V10A, N40S, A92N 
  clone: 3594 None    N41K, T91A N40S, A92N 
  clone: 3595 None    N41K, T91A N40S, D79G, A92N 
  clone: 3596 None    N41K, T91A N40S, A92N 
  MIN652_CVL-DNA
clone: 3597 
None    N41K, I64V, T91A N40S, A92N 
  clone: 3598 None    N41K, T91A N40S, I46T, A92N 
  clone: 3617 None   A73V K70R, R72K, T91A A92N 
  clone: 3618 None    T91A N40S, A92N 
  clone: 3619 None    T91A A92N 
  clone: 3620 None    N41K, T91A N40S, A92N 
  MIN652_PBMC
clone: 3621 
None    N41K, T91A N40S, A92N 
  clone: 3622 None    N41K, T91A N40S, I75V, A92N 
  MIN652_CVL-DNA
clone: 3629 
None    K70R, T77I, T91A A92N 
  MIN652_CVL-RNA
clone: 3874 
None    T91A N40S, A92N 
  clone: 3878 None    Q18R, N41K, T91A N40S, T80A, A92N 
  clone: 3879 None    F85L, T91A A92N 
  clone: 3880 None    R8G, N41K, I64V, T91A N40S, A92N 
  clone: 3881 None    N41K, I64V, T91A N40S, A92N 
  clone: 3882 None    N41K, I64V, T91A N40S, A92N 
  clone: 3883 None    N41K, T91A N40S, A92N 
  clone: 3884 None    T91A N40S, N41R, A92N 
  clone: 3885 None    N41K, T91A N40S, A92N 
  clone: 3886 None    N41K, T91A N40S, A92N 
  clone: 3951 None    N41K, T91A N40S, A92N 
  clone: 3960 None    K69R, T91A N40S, A92N 
  clone: 3961 None    A34T, N41K, I64V, T91A T26I, N40S, A92N