Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Dlamini (2011)
Title Genotypic resistance at viral rebound among patients who received lopinavir/ritonavir-based or efavirenz-based first antiretroviral therapy in South Africa.
Citation JAIDS
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 61
NumPts 61
Subtype C, A, D

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
1000751 1000751 NRTI NNRTI M184MIV K103N, E138A I31L, V35T, T39E, V111I, K122E, D123N, I142V, K173A, T200A, Q207A, R211K, F214L, V245Q, E248D, A272P, K277R  
1001668 1001668 NRTI NNRTI M184V K103N, M230L V35I, T39E, S48T, K122E, K173A, Q174K, D177E, I178M, T200A, E203D, R211K, V245Q, A272P, K277R  
1001734 1001734 NRTI NNRTI  Y188L, G190A V35T, E36T, T39E, K43Q, S48T, V90VI, K122E, D123N, I135V, S162C, K173A, D177E, G196M, T200A, E203K, Q207E, V245Q, Y271F, A272P  
1002583 1002583 NRTI NNRTI M184V Y188C E28K, K32E, V35T, E36A, T39E, K64R, A98S, K101N, K103KR, K122E, D177E, I178M, T200A, Q207A, R211K, V245Q, A272P, K277R  
1002617 1002617 NRTI NNRTI   V35T, T39E, K122E, D123G, K173A, D177E, I178M, T200A, Q207A, R211K, V245Q, D250E, A272K, K275Q  
1002658 1002658 NRTI NNRTI  K103N V35T, E36A, T39E, S48T, V60I, K122E, D123N, K173AT, T200A, Q207A, R211K, V245Q, A272P  
1003649 1003649 NRTI NNRTI   V35T, E36A, T39E, E40ED, S48T, K122E, D123S, S162SA, K166KR, K173A, D177E, I178IM, T200A, E204K, Q207E, R211K, V245Q, D250E, A272P  
1003797 1003797 NRTI NNRTI   P4S, V35T, E36A, T39E, S48T, K173A, Q174R, D177E, I178M, Q197QP, T200A, Q207A, R211K, V245Q, E248D, A272P, K277R  
1003805 1003805 NRTI NNRTI   V35T, E36A, T39E, K173AT, Q174R, D177E, I178M, T200A, Q207A, R211K, V245Q, E248D, D250DE, A272P, K277R  
1003813 1003813 NRTI NNRTI M184V K103KN, V106VM, M230ML V35T, T39E, S48T, K101KQ, K122E, I135IM, K173T, Q174R, D177E, T200A, Q207E, R211RK, V245Q, D250E, S251N, A272P, K275Q, K277R  
1004498 1004498 NRTI NNRTI M184MV  V35T, T39E, G45GR, G51GR, K122E, D123N, I135V, I142IMT, K173T, T200A, E203EK, Q207G, R211K, V245H, A272P, K277R  
1004852 1004852 NRTI NNRTI D67N, K70KR, T215S K101E, G190S V35T, T39E, S48T, K102Q, D121C, K122E, S162F, K173A, D177E, T200A, E204Q, Q207D, R211K, V245Q, E248D, A272P, K277R  
1004886 1004886 NRTI NNRTI   P4T, V35T, E36A, T39E, S48T, K122E, K173R, D177E, T200A, Q207E, V245Q, V276I  
1005081 1005081 NRTI NNRTI   V35T, T39E, S48T, K122E, D123T, T165I, K173A, D177E, I178M, T200A, Q207D, R211K, V245Q, E248D, A272P, K277R  
1005347 1005347 NRTI NNRTI M184V  V8I, V35T, T39EK, S48T, E53D, V60I, K122E, D123G, I135V, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, E248D, A272P, K277R  
1005545 1005545 NRTI NNRTI   V35T, E36A, I37F, T39E, S48T, V60I, K122E, D123N, I135V, S162C, K173A, D177E, T200A, Q207E, R211K, V245Q, A272P, K277G  
1005875 1005875 NRTI NNRTI   V8I, T27S, V35T, T39E, S48T, K122E, D123S, K173A, D177E, T200A, E204Q, Q207E, R211K, F214L, V245Q, K277R  
1006352 1006352 NRTI NNRTI  V106M V35T, E36A, T39E, S48T, K122E, D123G, T139M, S162C, E169D, K173A, D177E, T200A, Q207K, R211T, V245Q, A272P, K277R  
1007525 1007525 NRTI NNRTI   K32R, V35T, E40D, V60I, T69S, K122E, D123G, D177E, I178M, T200IM, Q207N, V245K, D250E, A272P  
1008622 1008622 NRTI NNRTI   V35T, T39E, S48ST, K122E, D123DG, K173AV, Q174QK, D177E, I178M, T200A, Q207E, R211K, V245Q, E248D, D250DE, A272P, K277R  
1008937 1008937 NRTI NNRTI  V106M, G190A K20R, V21I, V35T, T39E, S48T, V60I, K101N, K122E, D123S, T165I, K173A, Q174K, D177E, I178L, T200A, Q207A, R211K, V245Q, A272P, K277R  
1008978 1008978 NRTI NNRTI M184V  V35T, E36A, T39E, E40D, S48T, K122E, D123G, K173T, Q174K, I195L, T200A, Q207A, V245Q, A272P, K277R  
1008994 1008994 NRTI NNRTI   V35T, T39K, S48T, K122E, D123N, F171Y, K173T, Q174K, T200A, Q207E, R211K, V245Q, D250E, S251A, A272P, K277R  
1009000 1009000 NRTI NNRTI  E138EA K20KR, V35T, T39K, S48T, V60I, K122E, D123N, F171Y, K173T, Q174K, T200AV, R211K, F214L, V245Q, D250E, S251D, A272P, K277R  
1011113 1011113 NRTI NNRTI   K32R, V35T, E36A, T39E, E40D, S48T, K122E, D123G, E169K, K173E, D177E, T200A, Q207A, R211K, V245Q, A272P  
1011378 1011378 NRTI NNRTI M184V  V35T, T39K, S48T, V60I, K122E, D123DG, K173A, D177E, T200A, Q207K, R211Q, V245Q, K277R  
1012707 1012707 NRTI NNRTI M184V K101KE, K103NS, G190A V35T, E36A, T39D, V60I, D121Y, K122E, I135R, K173T, Q174K, D177E, D192DN, T200A, Q207E, R211K, V245K, A272P, K277R  
1013234 1013234 NRTI NNRTI M184V  V21I, K32E, V35T, E36A, T39E, S48T, V60I, K122E, D123S, I135R, K173M, D177E, T200A, Q207E, V241VL, V245Q, A272P  
1015973 1015973 NRTI NNRTI M184V  P4S, V35T, E36A, T39E, S48T, K122E, D123N, I135M, S162C, K173A, Q174R, D177E, T200A, Q207A, R211K, V245Q, A272P, K277R  
1016088 1016088 NRTI NNRTI A62AV, K65KR, D67H, M184V, K219E V106M, E138KQ, G190A K11Q, V35T, E36A, T39E, S68G, T69N, D121Y, K122E, I135R, S162C, K173A, Q174K, D177E, T200A, Q207A, R211K, K223KE, V245Q, A272P  
1016203 1016203 NRTI NNRTI   V35T, E36A, T39E, S48T, K101Q, K122E, D123N, I142IV, K166KR, K173AT, D177G, V179I, T200A, Q207E, V245Q, A272P, K275Q, K277R  
1017557 1017557 NRTI NNRTI   V35T, E36A, T39E, S48T, K173A, D177E, T200A, Q207AV, R211K, V245Q, A272P, K277R  
1018381 1018381 NRTI NNRTI M184V K103N, P225PH K22R, T27S, E28K, V35T, E36A, T39E, S48T, K101Q, K122E, D123S, K173T, D177E, T200A, Q207E, R211K, V245Q, D250E, S251D, A272P, K275Q  
1020726 1020726 NRTI NNRTI  K103N V35T, E36A, T39E, S48T, V60I, K122E, D123G, K173V, Q174R, D177E, T200A, Q207E, R211K, F214L, V245Q, E248Q, A272P, K277R  
1022367 1022367 NRTI NNRTI   V35T, V60I, D121Y, K122E, R125K, D177E, I178M, T200E, Q207G, R211K, P243S, V245K, A272P, K277R  
2000701 2000701 NRTI NNRTI   V35T, E36A, T39E, S48T, V60I, K122E, D123G, K173A, D177E, I178M, T200A, Q207E, R211K, F214L, V245Q, E248D, A272P, K277R  
2001238 2001238 NRTI NNRTI   V35T, E36A, T39E, S48T, V60I, D121Y, K122E, T165I, K173T, D177E, T200A, Q207E, V245K, A272P  
2001261 2001261 NRTI NNRTI   V35T, E36A, T39E, S48T, V60I, K122E, D123S, K173T, D177E, T200A, Q207E, R211K, V245K, A272P, K277R  
2003630 2003630 NRTI NNRTI  K103N, V106VM K20R, K32R, V35T, E36A, T39E, S48T, V60I, K122E, D123DG, K173T, Q174K, D177E, I178IM, T200A, Q207A, R211K, V245Q, A272P  
2003713 2003713 NRTI NNRTI   V8I, V35T, T39E, S48ST, K122E, D123N, K173T, Q174KR, T200A, Q207E, R211K, F214L, A272P  
2004521 2004521 NRTI NNRTI   E28K, K32E, V35T, E36A, T39E, S48T, V60I, K122E, D123G, K173A, Q174R, D177E, G196E, T200A, Q207E, R211K, V245Q, A272P, K275Q, K277R  
2005726 2005726 NRTI NNRTI   E28A, V35T, V60I, K122E, D123S, I135T, I142V, K173L, Q174K, D177E, V179T, T200A, Q207A, R211S, F214L, V245R, D250E, K277R  
2006344 2006344 NRTI NNRTI   V35T, E36A, T39D, S48T, V60I, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, K277R  
2006575 2006575 NRTI NNRTI   E6K, K11T, V35T, T39A, S48E, K173A, D177E, V179I, T200A, Q207A, R211S, V245Q, A272P  
3000346 3000346 NRTI NNRTI   V35T, T39E, S48T, I50V, K122E, S162C, K173T, Q174K, D177E, T200A, E204D, Q207A, R211K, V245Q, A272S, K275R  
3002128 3002128 NRTI NNRTI   T27S, V35T, T39N, S48T, K122E, D123DG, K173A, Q174K, D177E, T200A, R211K, V245Q, K277R  
3002177 3002177 NRTI NNRTI  K103KN P4S, K20R, V35T, E36EA, T39E, S48T, V60I, K122E, D123S, I135V, T165TI, K166KR, K173A, Q174K, D177E, T200A, Q207AD, R211KQ, F214L, V245Q, A272P, K277R  
3002367 3002367 NRTI NNRTI D67DN, K70KR V106M V35T, T39E, S48T, V60I, K64R, K102KR, K122E, D123G, S163ST, T165I, K173T, D177E, T200A, Q207E, V245HQ, A272P  
3003480 3003480 NRTI NNRTI   K32N, V35K, E36A, T39E, S48T, K122E, D123S, K173T, Q174K, D177E, T200A, Q207D, R211K, V245Q, E248T, A272S  
4000667 4000667 NRTI NNRTI   V35T, E36A, T39E, S48T, K122KE, D123G, K166R, K173A, Q174KR, D177E, T200A, Q207E, R211RK, K238R, V245Q, A272S, K277R  
4001848 4001848 NRTI NNRTI   D17E, V35T, E36A, T39E, E40D, S48T, K122P, D123E, S162C, Q174K, D177E, T200A, Q207E, V245Q, A272P, K277R  
4002325 4002325 NRTI NNRTI   K20R, V35T, E36A, T39E, S48T, V60I, K102Q, K122E, D123S, K173A, D177E, Q207K, R211K, V245Q, A272P, K277R  
4002960 4002960 NRTI NNRTI M184V K101E, K103N V35R, E36A, T39E, E53D, T139R, Q145E, S162Y, K173T, D177E, T200A, I202V, Q207G, V245Q, A272P  
4003620 4003620 NRTI NNRTI   M16T, V35T, E36A, T39E, S48T, K122E, D123N, S162Y, K173A, T200A, Q207E, R211K, A272S  
4003760 4003760 NRTI NNRTI   V35T, E36A, T39D, S48T, V60I, K122E, D123G, K173AT, Q174K, D177E, I178L, T200EQ, Q207E, R211K, V245Q, E248V, A272P  
4004263 4004263 NRTI NNRTI   V35T, E36EA, T39E, S48ST, A98S, K122E, D123N, K173A, Q174R, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R  
4004875 4004875 NRTI NNRTI   V35T, T39E, S48T, V60I, K122E, D123N, T139V, K173T, Q174K, D177E, I178M, T200A, R211K, V245Q, A272P, K275R  
5000559 5000559 NRTI NNRTI K70R E138A Q23P, V35T, T39E, S48T, K64R, D86E, W88S, K122E, D123S, I135T, S162H, E169R, K173T, I178L, T200A, Q207E, R211K, F214L  
5001110 5001110 NRTI NNRTI   V35T, E36EA, T39E, S48T, V60VI, K122E, D123S, I135T, S162SC, K166KR, K173A, D177E, T200A, E204K, Q207A, R211RK, F214L, V245Q, A272P, K277KR  
5001367 5001367 NRTI NNRTI  E138K V35T, T39K, S48T, D121Y, K122E, S162C, K173Q, Q174K, G196E, T200A, Q207D, R211K, V245Q, A272S, K277R  
5001714 5001714 NRTI NNRTI M184V A98G, K103N V35T, T39E, S48T, D121H, K122E, D123N, T139A, K173A, Q174K, N175Y, D177E, G196V, T200A, K201KR, I202IV, Q207E, I244V, V245Q, D250E, S251D, A272P, K277R  

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