Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Konou (2015)
Title Virological outcome among HIV-1 infected patients on first-line antiretroviral treatment in semi-rural HIV clinics in Togo.
Citation AIDS Res Ther
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 67
NumPts 67
Subtype CRF02_AG, CRF06_cpx, A, G, C

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
AN008 AN008 NRTI NNRTI  Y181YC, G190GA E6N, K11T, V35T, E36A, T39K, K43E, K102Q, K122E, D123S, I142V, S162H, K166KR, E169D, R172RK, K173L, Q174K, D177E, V179I, I202V, Q207D, R211K, V245Q, E248N  
AN012 AN012 NRTI NNRTI  K103N V35T, V60I, K122E, D123E, S162A, K173T, Q174K, D177E, I178M, T200A, R211K, P243S, V245T  
AN019 AN019 NRTI NNRTI M41L, V75I, M184V, T215F Y181C, H221Y V35T, V60I, I132L, I135V, S162A, K173T, Q174E, D177E, T200A, Q207E, R211K, F214L, V245K  
AN021 AN021 NRTI NNRTI M41ML, M184V, T215F Y181V E6N, K11T, V35T, T39K, K43E, S68G, V90I, K122E, D123N, I135T, I142V, S162Y, K173A, Q174K, D177E, I178L, V179I, Q197H, T200A, Q207E, R211K, V245Q  
AN022 AN022 NRTI NNRTI M184V Y181C V21I, V35T, T39K, K43E, K49R, I50V, V60I, D123N, S162SC, Q174A, D177E, I178M, T200A, Q207E, R211K, K223KT, F227X, L228LR, V245Q, E248D, D250E  
AN026 AN026 NRTI NNRTI M41L, A62V, M184V, K219N Y181C, G190A V35I, E36D, A98S, D121C, K122E, I135V, S162A, K173T, Q174K, D177E, G196E, T200A, Q207E, R211K, L228R, E248D  
AN028 AN028 NRTI NNRTI D67N, K70R, M184V, T215F, K219E V108I, Y181C V35R, E36D, T39E, V60I, T69TN, V90I, A98S, D123E, I135L, S162A, D177E, T200A, Q207E, L228H, V245E, D250E  
AN032 AN032 NRTI NNRTI  Y181YC, G190GA, H221HY K11T, V21I, V35T, E36D, T39L, V60I, V90I, D123N, I135V, S162A, Q174N, D177E, T200A, Q207E, R211K, F227FY, L228LR, V245Q  
AN041 AN041 NRTI NNRTI A62V, K65R, K70T, V75I, F116Y, Q151M, M184V K103N, Y181C I31IL, V35I, E36D, T39S, S68G, T69I, K102M, V111I, I135L, S162A, K173V, Q174K, D177E, T200A, Q207K, H208Y, R211E, E248D  
AN043 AN043 NRTI NNRTI M184V, T215F K101E, Y181C, G190A K20R, V21I, V35T, T39M, V60I, D121Y, K122E, I135V, S162AT, K166KR, K173T, Q174K, D177E, T200A, Q207K, R211E, V245Q, E248D  
AN048 AN048 NRTI NNRTI D67N, K70R, M184V, T215F, K219E V108I, Y181C, K238T V35T, E36D, T69N, K122PQ, I135V, E169Q, K173A, D177E, T200A, Q207E, R211K, L228H, V245Q  
AN049 AN049 NRTI NNRTI M184V K103N V35T, K49R, V60I, I135T, E169D, K173R, Q174K, N175Y, D177E, T200A, K201I, Q207E, R211Q, V245Q, E248D  
AN052 AN052 NRTI NNRTI M184V K103KN V21I, T27S, K32KR, V35T, T39S, V60I, K122A, D123DN, I135IT, I142V, Q174K, N175NY, I178LM, T200E, Q207E, R211K, V245Q, E248D  
AN054 AN054 NRTI NNRTI M41L, L74I, M184V, L210W, T215Y A98G, K103N, K238T V35T, E44D, V90I, I94L, D123E, I135V, K173A, Q174R, D177E, T200A, Q207E, R211K, V245Q  
AN058 AN058 NRTI NNRTI A62AV, M184V V106A, F227L V35T, T39A, V90I, K122E, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207N, R211K, P243A, V245Q  
AN059 AN059 NRTI NNRTI M41L, M184V, T215Y K103N V35M, E36D, K49R, S68SG, V90I, I135V, S162D, E169K, K173A, Q174K, D177E, I178M, T200A, E203ED, Q207E, V245Q  
AN068 AN068 NRTI NNRTI M41ML, M184V, T215Y A98AG, Y181C, H221Y K20R, E29EK, V35T, S68G, K122E, I135T, S162AT, K173A, Q174K, G196R, T200A, Q207E, R211K, F214L, V245Q  
AN074 AN074 NRTI NNRTI M184V K101E, G190A E28EK, V35T, V60I, S68G, T69N, I135T, S162C, E169D, K173T, Q174K, D177E, I178L, T200A, Q207E, R211K, V245Q, E248D, D250E  
AT400 AT400 NRTI NNRTI K70KR, M184V Y181C V35L, I135R, T139IMR, S162A, K173T, Q174E, D177E, I178M, T200A, E204K, Q207E, F214L, V245Q, E248D  
AT403 AT403 NRTI NNRTI M184V  K11T, V35T, E36A, T39K, K43E, K122E, D123S, I142V, S162N, K173S, D177E, V179I, E203D, Q207A, R211K, V245K, E248D, D250E  
AT407 AT407 NRTI NNRTI M41L, D67N, K70R, V75IM, M184V, T215F, K219Q K101E, G190A K20R, E28EK, K32E, V35T, V60I, K122E, I135T, S162A, K173T, Q174K, D177E, I178M, Q197H, T200A, Q207A, R211K, V245Q, E248D  
AT411 AT411 NRTI NNRTI M184V Y181C, G190A V35I, T139R, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, V245Q  
AT420 AT420 NRTI NNRTI M184V K103N V35K, K122P, I135V, S162AT, K173R, Q174E, D177E, T200A, E203K, Q207E, K223KT, V245Q, E248D  
AT423 AT423 NRTI NNRTI M41L, M184V K103N V35T, V60I, D123E, T165L, Q174K, D177E, T200A, Q207E, R211K, V245Q, E248D, D250E  
AT426 AT426 NRTI NNRTI K65R K101EQ, Y181C, G190S V35T, T39K, K43E, S68G, V90I, I135V, P157A, S162A, K173A, Q174A, D177E, T200A, Q207E, R211K, V245Q, E248D F116W 
AT435 AT435 NRTI NNRTI M41ML, D67DN, K70KR, M184V, T215Y, K219KE A98G, V108I, Y181C, H221Y V35T, E36D, V60I, V90I, I135V, S162A, K173T, Q174E, D177E, T200A, Q207K, R211H, V245Q  
AT442 AT442 NRTI NNRTI M184V Y181C V35T, K101Q, K122E, D123N, I135V, T139R, S162A, K166KR, K173T, T200A, Q207E, T215X, V245Q, P247A  
AT452 AT452 NRTI NNRTI M41L, M184V, T215Y A98G, Y181C K20R, V35R, K103R, K122E, D123N, I135L, S162A, T165L, K173T, Q174K, D177E, I178M, T200A, Q207E, V245Q  
AT456 AT456 NRTI NNRTI M184V, T215F K101E, G190A E28EK, V35T, V60I, S68G, K173T, Q174K, D177E, T200A, Q207D, R211K, V245Q  
AT463 AT463 NRTI NNRTI   V35T, E36D, T39A, K122P, D123DN, I135V, S162A, K173I, Q174K, D177E, I178V, T200A, Q207E, R211K, F214L, V245Q, D250E  
AT477 AT477 NRTI NNRTI M184I K103N P1PS, K20R, V21I, E29EG, V35T, T39L, E40D, V60I, V90I, I135T, S162C, S163T, K173T, Q174K, D177E, T200A, Q207G, R211K, V245Q, E248D, D250E  
KA305 KA305 NRTI NNRTI M41L, M184V Y181C V35T, T39E, V60I, K122E, D123N, I135R, I142V, T165L, E169D, D177E, G196E, T200A, Q207E, R211K, V245Q, E248D, D250E  
KA308 KA308 NRTI NNRTI M184V, T215Y K103N, Y181C, H221Y V21I, V35Q, V60I, D121Y, K122E, I135T, K173T, Q174K, T200A, I202V, Q207E, R211K, P243T, V245Q, E248D, D250E  
KA319 KA319 NRTI NNRTI D67N, K70R, M184V, T215F, K219Q K103N, Y181C K20R, V35T, T39N, V60I, A98S, D123E, I135R, S163T, T165L, K173A, Q174K, D177E, T200A, E203K, Q207E, R211K, V241M, V245Q, D250E  
KA344 KA344 NRTI NNRTI M41L, D67DN, K70KR, M184V, T215Y K101E, G190A K20R, E28K, V35T, V60I, D121Y, K122E, D123E, K173A, Q174K, D177E, I178M, T200A, Q207E, R211K, P243A, V245Q, D250E  
KA348 KA348 NRTI NNRTI M184V V179E, Y181C V35T, V60I, K102R, K103R, K122P, K173R, Q174K, T200V, Q207E, R211K, F214L, V245Q, E248D, D250E  
KA350 KA350 NRTI NNRTI M41L, M184V K101E, G190A T7TP, E28G, K30KE, V35T, T39K, V60I, K173T, Q174K, D177E, T200A, Q207E, R211K, V245M, D250E  
KA366 KA366 NRTI NNRTI M41L, M184V, L210W, T215Y K101E, V108I, Y181C, G190A, H221Y K32I, L34I, V35T, T39L, K49R, E53EK, V60I, D121Y, K122E, I135R, S162A, K173T, Q174R, D177E, I178L, T200A, Q207N, R211K, V245Q, E248D  
KA378 KA378 NRTI NNRTI M41L, M184V, L210W, T215Y Y181C K11T, V35T, T39K, K43E, V60I, D121H, K122E, D123S, I135T, T139R, I142V, S162Y, K173T, Q174K, D177E, I178L, V179I, T200A, E204Q, Q207D, R211K, L228R, V245Q, E248D  
KA379 KA379 NRTI NNRTI M184I, K219N K103N, V179E, Y181C V35T, E40D, V90I, K122P, S162A, K173A, Q174K, D177E, I178IM, T200A, Q207E, I244V, V245E, D250E  
KO100 KO100 NRTI NNRTI M41L, M184V, T215F Y181C K20R, V35T, V60I, D123E, I135R, T139R, K173T, Q174K, D177E, T200A, Q207E, R211K, V245Q  
KO112 KO112 NRTI NNRTI M184V, K219R A98G, K103N, V108VI, P225H K20R, V35T, K70X, K122V, I135IV, S162A, K173A, Q174K, D177E, T200A, Q207E, R211K, F214L, L228R  
KO116 KO116 NRTI NNRTI M184V K103N V35T, V90I, K104Q, D123E, S134SR, I135V, T139K, S162A, K173A, Q174K, D177E, I178M, T200A, E204ED, R211K, V245K  
KO122 KO122 NRTI NNRTI M41L, D67N, K70R, M184V, T215Y A98AG, V108I, V179E, Y181C, H221Y K20R, V35T, T39N, D121H, K122E, I135T, I142V, K173T, Q174KR, T200A, E203ED, Q207E, R211K, V245Q, E248D, D250E  
KO130 KO130 NRTI NNRTI M184V, T215F K103N, E138K, V179E, K238T V35T, E36D, V60I, S68G, K122E, D123N, I135L, S162T, K173AV, Q174K, D177E, I178L, T200A, Q207E, R211K, D237E, V245Q  
KO137 KO137 NRTI NNRTI M184V, T215Y G190A, M230L K11T, K22KN, E28EK, K32E, V35T, E36A, T39K, K43E, K122E, D123N, I135T, I142V, S162CY, K173S, Q174K, D177E, V179I, T200A, E203D, R211K, V245Q, E248N, D250E  
KO148 KO148 NRTI NNRTI M184V K103N V35T, T39M, V90I, I135V, S162A, K173T, Q174K, D177E, I178L, T200A, Q207D, R211K, V245Q  
KO150 KO150 NRTI NNRTI M184V K103N, Y181C E29EK, V35T, T39S, D121Y, K122E, T139KR, S162A, K173D, Q174K, D177E, V189I, T200A, I202V, Q207V, R211N, V245Q  
KO158 KO158 NRTI NNRTI D67N, K70R, M184V, T215F, K219E A98AG, K101E, Y181C V35T, V60I, D123E, I135V, T139R, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, V245Q, D250E  
KO193 KO193 NRTI NNRTI M184V A98G, K103N V35T, V90I, K102R, D123E, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, V245K  
KO195 KO195 NRTI NNRTI  Y181YC V35T, K43Q, K122P, S162A, S163T, K173T, Q174K, D177G, T200A, Q207EG, R211K, V245Q, E248D  
KO197 KO197 NRTI NNRTI M184V G190A K11T, V35T, E36A, T39K, K43E, K49R, V90I, K102Q, K122E, D123N, I142V, S162D, K173S, Q174K, D177E, V179I, T200A, Q207E, R211K, V245Q, E248D  
KO200 KO200 NRTI NNRTI  E138EG V35T, K122KE, I135V, S162C, K173V, Q174K, D177E, I178M, T200A, R211K, V245Q, E248D  
KO203 KO203 NRTI NNRTI M184V, T215Y Y181C, H221Y V8VI, I31L, V35T, V60I, R78RK, V90I, K122E, D123N, S162C, E169D, K173R, Q174K, D177E, I178L, T200A, Q207E, R211K, V245Q, E248D, D250S  
KP202 KP202 NRTI NNRTI M184V, T215Y V108I, Y181C, H221Y V35T, K49R, V60I, S68G, K122E, I135V, S162A, K173T, Q174K, D177E, V179I, T200A, Q207E, R211K, V245Q, P247Q, E248T  
KP206 KP206 NRTI NNRTI M184V K103N, P225H K22KR, K32R, V35T, E36A, T39E, A98S, K104KR, K122A, I135L, K173T, D177E, I178L, Q197E, T200K, Q207E, R211K, P243S, V245Q, E248D  
KP210 KP210 NRTI NNRTI M184V G190S V35T, T39N, V90I, K122P, A158S, S162A, K173T, Q174K, D177E, T200A, Q207E, V245Q, D250A  
KP213 KP213 NRTI NNRTI M184V, T215TS A98G, K103N V35T, E36D, T39N, E40D, V60I, K122P, I135M, S162A, K173T, Q174K, D177E, T200A, E203D, Q207E, V245Q  
KP218 KP218 NRTI NNRTI M184V K101KE, V108I, G190A K20R, V35T, E36A, T39E, E40D, V60I, K122P, I135V, Q174R, D177E, I178F, V189I, T200A, Q207E, R211K, V245Q, E248D  
KP221 KP221 NRTI NNRTI M41L, V75I, M184V, T215F K103N, E138Q V35T, T39N, V60I, A98AS, K122E, I132L, I135T, T165X, Q174E, D177E, I178IM, T200A, I202V, E204K, Q207E, R211T, F214L, V245Q, E248D  
KP223 KP223 NRTI NNRTI M41L, D67N, K70R, V75I, M184V, T215F, K219E K103N, Y181C, H221Y K20R, K22KR, V35T, E36D, K49R, V60I, V106L, D121N, K122E, D123Q, R125K, I135V, A158S, S162N, R172K, K173I, Q174K, D177E, V179A, R199K, E203K, R206K, Q207K, R211E, D218N, V245E, D250E, S251G Q85H, R143I, N147S, V148A, E169H, D185N, G190P 
KP234 KP234 NRTI NNRTI M41L, M184V K103N V35K, T39A, V60I, V90I, K101Q, K122E, T165L, K173R, Q174K, D177E, G196E, T200A, Q207E, R211K, V245Q, E248D, D250E  
KP235 KP235 NRTI NNRTI M184V A98AG, K103N, V108VI, E138Q V35T, E36D, V90VI, K122A, I135V, S162A, K173T, D177E, V179T, T200A, Q207E, R211Q, V245Q  
KP241 KP241 NRTI NNRTI M41L, M184V, L210W, T215F Y181V, H221Y V35K, E36D, K43Q, D123E, I135T, S162A, K173T, Q174K, N175Y, D177E, T200A, E203K, Q207D, R211K, V245E V111VIM 
KP243 KP243 NRTI NNRTI M41L, D67N, V75M, M184V, L210W, T215Y K101E, G190A E28K, K32E, V35T, T39N, E44D, V60I, W88C, V118I, K122E, S162N, Q174E, D177E, I178M, T200A, E203K, Q207E, R211I, K223Q, V245Q, D250E  
KP253 KP253 NRTI NNRTI M184V K103N, V108I V35M, T39M, V90VI, K104R, K122P, I135M, S162A, K173T, Q174K, D177E, Q207E, R211K, V245Q, E248D  
KP280 KP280 NRTI NNRTI M184V K103N, K238N V35T, E36D, V60I, K122E, D123N, I132V, I135V, S162A, K173T, Q174K, D177E, I178V, T200A, I202V, Q207E, F214L, L228R, V245Q, E248D