Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Mueller (2007)
Title Dual selection pressure by drugs and HLA class I-restricted immune responses on human immunodeficiency virus type 1 protease.
Citation J Virol
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 94
NumPts 94
Subtype B, CRF01_AE, C, D, A, CRF69_01B

 

Clinical PR Isolates


SubjectIsolatePIsWksPIMajorPIMinorCommonUnusual
00001382 00001382 PI  M46I, I84V L10F T4I, P9T, I13V, K20I, N37S, R41K, K55R, D60E, I64V, L89M, I93L R8T 
00001784 00001784 PI    E35D, L63P, I64IM, A71X, V77I, I93L  
00002001 00002001 PI    T12P, K14R, E35ED, P39S, L63PT, A71V, I72IM, V77I, I93L  
00002348 00002348 PI    I15V, E35D, N37NK, I62IV, L63AT, I64M, I72IV  
00002626 00002626 PI    R57K, D60E, L63P  
00003618 00003618 PI    E35D, L63P, H69R L5LMV 
00003817 00003817 PI    T12TS, P39S, I62IV, L63P, A71T  
00004804 00004804 PI  L90M G73T L5F, L10IM, I13IM, I15V, K20R, D25DE, E35D, M36I, R57K, D60E, I62V, L63P, V82I, I93L R8R*G 
00004854 00004854 PI  V32VI  L10I, T12AS, I13V, L19LV, K20KIM, M36MI, R41K, I64V D25DY, A28AG, T31TI 
00004919 00004919 PI    T12N, I62V, L63A, I72E, V77I, V82I  
00006524 00006524 PI    T4I, W6WGR, Q7E, I15V, L19V, N37E, L63T, I93L R8R*G 
01001093 01001093 PI    R41K, L63P, K70R  
01001604 01001604 PI    L19V, E35D, K43R, L63P, I93L  
01002403 01002403 PI    L19I, N37D, K43R, I62ILV, L63P, V77I, I93L  
01003242 01003242 PI   L23LIV, L24LF L5X, L10I, I13V, G16E, L19LIV, E35D, N37T, Q61H, L63C, I64V, K70R, P79X, I93X, G94X I84IM, I85IM 
01007239 01007239 PI    E35D, R57K, L63P  
02001292 02001292 PI    E35D, N37S, I64V  
02002033 02002033 PI  V32I, M46L, V82M, L90M L33LF, K43T L10I, T12S, I15V, L19Q, K20R, E35D, M36I, N37S, R57K, L63P, I64V, H69Y, I72IM, I93L  
02002469 02002469 PI    I13IL, L63H, I64L, I72V, V77I, I85IV D25DY 
02003727 02003727 PI    D60E, Q61E, L63P, I64L, V77I  
02006431 02006431 PI  M46L, I54V, V82A, L90LM L10FI, L24LI, L33F, F53FL, G73GS T4TP, I13IV, K14KR, I15V, K20R, E35D, M36I, N37E, R41K, I62IV, L63P, A71IT I85IMV 
03001695 03001695 PI  I54V, V82A  L10I, I13V, G16E, L19I, K20I, E35DH, M36I, P39S, R41K, D60DE, I62V, H69K, K70R, A71V, I72V, T74A, L89I  
03001929 03001929 PI  D30N N88D R41K, Q61E, L63P, A71T, V77I, I93L  
03002165 03002165 PI  G48V, I54T, V82S L33F Q7QH, L10I, E34Q, N37S, D60E, I62V, L63P, K70N, A71I, V77I I15IT, L38LS 
03004420 03004420 PI    N37S, I62V, L63S, V77I  
03004892 03004892 PI  M46L, I54IL, L76LV, V82A, I84IV L24I, L33F, G73GS L10I, I13LV, I62V, L63P, A71V, Q92QK  
040000367 040000367 PI    K14R, I15V, L19I, M36I, R41K, L63T, H69K, I93L  
04001739 04001739 PI  M46I, I84V, L90M F53FL, G73S K20I, E35D, M36I, I62V, L63P, A71V  
04003234 04003234 PI    I13V, I15V, E35D, N37E, L63P, H69K, V77I  
04003238 04003238 PI    I13V, R41K, I62V, L63PS, H69K, T74A  
04003984 04003984 PI  M46L, I54V, V82A, L90M L23I, K43T, F53L, T74P L10I, I15V, K20R, M36I, R41K, I62V, L63P, A71V, I72T, I93L  
04004094 04004094 PI  V32I, M46I, I47A, V82A L10F, L33F R57K, L63P, A71V, I72V, V77I, I93L  
04004491 04004491 PI    I13V, E35D, M36I, R41K, H69K, L89M  
04004599 04004599 PI   L23LI I15V, L19LI, E35D, M36I, N37D, L63P, H69K, T74S, P79PS, L89M, I93L A22AD 
04004746 04004746 PI    T12K, K14Q, N37NT, R41K, I62V, L63C, I64IV, E65ED  
04004900 04004900 PI    L10I, T12P, K14R, N37D, L63P, C67D, H69K, V77I, I93L  
04005157 04005157 PI    M36MI, R41K, K43R, I64IV  
04005572 04005572 PI    E35D, N37D, L63AP  
04006908 04006908 PI    T12P, L19I, K43R, I62V, L63P, H69T, A71AV, I93L  
04007659 04007659 PI    L10I, K43KR, L63P, I64IV, V77VI, I93L  
05000228 05000228 PI    L10I, E35D, M36MI, N37D, D60DE, L63LP, A71AV, I72IR, I93L  
05001683 05001683 PI    E35D, N37NST, R57K, L63P  
05002004 05002004 PI    N37NS, P39PQ, I62V, L63V, A71V, V77VI, I93L  
05002430 05002430 PI  V32I, M46I, I54V, V82A K43T, F53L L10I, I15V, K20R, M36L, N37S, L63P, H69K, A71V, I85V  
05003721 05003721 PI    I3V, L10M, I15V, L19I, M36I, R41K, L63AT, H69K, L89M, I93L  
05004197 05004197 PI    L10I, I13V, K14KR, M36I  
05004251 05004251 PI    L10V, I13V, I64V  
05004444 05004444 PI    T12A, Q18E, M36I, L63P, I64V, I93L  
05006426 05006426 PI    L10LI, I62V, L63P, H69HN  
05006432 05006432 PI    L10I, T12TA, M36MI, I62V, L63N, I93L  
05007474 05007474 PI    K20KR, L33I, M36MI, N37S, P39S, R57RK, L63P, A71V, I93L  
05007841 05007841 PI    I15V, G16E, E35D, K45R, L63T, I64V, E65D, Q92K  
05007850 05007850 PI    I15V, G16E, E35D, K45R, L63T, I64V, E65D, Q92K  
05008000 05008000 PI  I54V, V82T, I84V, L90M L33F, Q58E, T74P L10I, I13V, K20R, E35D, M36I, N37D, I62V, L63P, I66IF, A71V  
05066528 05066528 PI    T12S, I15V, L19LI, R41K, L63S, I64V  
06a11924 06a11924 PI  M46L, I50V, I54V, V82A L23I, L24I, L33F, Q58E L10I, I15V, G16E, K20R, E35D, M36I, D60E, I62V, I64V, A71V, I72R V56VA 
96005942 96005942 PI  V82F, L90M  L10I, E35D, M36I, N37D, I62V, L63P, A71V, T74A, V77I, I93L  
97000772 97000772 PI  M46L, I84V, L90M L33F I13V, I15V, R41K, Q58X, L63P, R87X  
97001762 97001762 PI    I13V, G16E, K20R, E35D, M36I, L38LW, R41K, H69K, K70R, I72V, L89M D29DG 
97001980 97001980 PI    I15V, L63A, I85V  
97003516 97003516 PI  I54V, L90M  L10I, E35D, M36I, N37D, D60E, L63P, A71V  
97004087 97004087 PI  M46I  I15V, L19I, E35D, R57K, L63P, A71T, I93L V82R 
97004898 97004898 PI  M46L, I54V, V82A L24I L10I, L63P, H69N, A71V, V77I T31N 
97005068 97005068 PI  M46I, L90M G73T L10I, R41K, L63P, I72L, V77I, I93L  
97005839 97005839 PI    L63P, A71V, V77I, I93L  
97005850 97005850 PI    E35D, M36I, N37S, R41K, R57K, H69K, L89M, I93V  
97006341 97006341 PI    I13V, K20R, N37D, R41X, Q61QH, L63S, I64V, E65D, V77I, L90LF  
98001308 98001308 PI  M46I, I84V, L90M G73T L10I, K14KN, Q61E, I62V, L63P, A71V, V77I, P79S, I93L  
98001947 98001947 PI  M46I, L90M G73T L10I, R41K, I62M, L63P, I72L, V77I, I93L  
98002477 98002477 PI    T12Q, N37D, L63P, A71T, I93L  
98002704 98002704 PI  M46L, G48V, V82A, L90LM  L10LV, L33V, G40GR, L63LP, I64V  
98002867 98002867 PI  D30N  K43X, L63P, I64V, H69N, V77I  
98004517 98004517 PI  V82VA  I15V, M36I, R41K  
98004812 98004812 PI  M46I, V82T  I3V, E35D, L63P, I64V, I93L  
98005106 98005106 PI    I15V, E35D, D60E, Q61E, L63P G49GA 
98005220 98005220 PI    L63P, H69N, V77I  
98006014 98006014 PI    Q7K, L10X, L19Q, E35ED, L38LIV, I47X, L63P, I93X I15T 
98006220 98006220 PI  L90LM  L10LI, E35ED, M36MI, I62IV, L63LP, I64IL, A71AT, V77VI, I93IL  
98006271 98006271 PI    L63LP, V77I, I93IL  
98006368 98006368 PI  L90LMV  T4P, L23F, E35D, M36V, N37D, D60E, I62V, L63P, V77I, I93L L24W, D25Y, T26K 
98006861 98006861 PI  L90M  L10I, I15X, R41K, I47X, R57K, D60E, Q61E, L63P, V77I, I93L  
98007114 98007114 PI  M46L  N37S, I62V, L63V, A71V, I93L I15T 
98007149 98007149 PI    L63T, I72T  
99001912 99001912 PI  V82T  T12S, K45KR, I62IV, L63P, V77VIM, I93L  
99002539 99002539 PI    K14R, L19Q, L23F, M36I, L38LM I47IK 
99002805 99002805 PI    I13V, E35D, M36I, P39S, R41K, H69K, L89M E65EA 
99003445 99003445 PI   L89LMV I13V, G16E, N37C, I62V, L63S, I64M, E65D, V77I  
99003646 99003646 PI    M36MI, R57RK, L89LM  
99003653 99003653 PI    I13V, K14R, E35D, M36I, R41K, H69K, L89M  
99004226 99004226 PI  M46ML  K14KT, G16GR, Q18QL, K20KM, R41RT, K45KN, I47IM, I62IV, L63P, H69N L24LV, T26TS, V32VL, P44PL, V56VL, Y59YC 
99004342 99004342 PI    E35D, L63P, E65D, K70R R8R*G, I66IM 
99005306 99005306 PI  M46ML, I84V, L90M G73S L10I, K20IM, N37D, D60DE, L63P, A71V, V77I, I93L  
99007195 99007195 PI    N37D  
99007403 99007403 PI    L10I, I62V, L63N, A71T, I72M