Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Delatorre (2017)
Title HIV-1 Genetic Diversity in Northeastern Brazil: High Prevalence of Non-B Subtypes.
Citation ARHR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 140
NumPts 140
Subtype B, F, C, CRF29_BF, CRF12_BF, CRF02_AG, D


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Page 1   listing Isolate 1 to Isolate 100 from Total 140 Clinical RT Isolates

SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
07BA140665 07BA140665 RTI RTI   I50IV, S68SG, K122E, D123Q, I135V, S162A, K173R, Q174K, Q207E, R211K, F214FL, V245LQ, E248ED, K249KQ, D250X, A272P, K277R, T286A, A288S, Q334N, G335D  
07BA140666 07BA140666 RTI RTI  G190GE D123E, R172K, I178L, K220KE, P243R, V245E, A272P, I329V, Q334P  
07BA140667 07BA140667 RTI RTI M41L, M184V, L210W, T215Y  K20R, V21I, E44D, V118I, D121Y, K122E, I135T, S162A, D177E, V179I, T200A, K223Q, Q278H, K281R, L283I, I293V, E297T  
07BA140669 07BA140669 RTI RTI   V35T, K49R, D123E, S162C, E169D, K173IM, Q174K, Q197E, Q207A, R211K, V245Q, E248D, A272P, K277R, T286TA, E291ED, V292I, I293V, E297K, G333E, G335S  
07BA140672 07BA140672 RTI RTI K70KR, L74I, M184V, K219Q K103N, V108I, P225H K20KR, K102KR, I135T, K173N, I178M, T200A, V245IM, A272P, I293V, G335GS  
07BA140674 07BA140674 RTI RTI K65R, V75VIM, M184MI K101E, G190CS V35VI, T39TA, S68G, V90I, A98S, K102Q, I135T, S162CY, G196GR, R211K, E224EK, P243T, V245Q, T286A, I293V, E297A, D324E, Q334L  
07BA140675 07BA140675 RTI RTI   K20KR, V21I, T27TS, V35KT, T39TA, V60I, R83RK, D123DE, I135IT, S162A, Q174QK, R211RK, E248D, A272S, T286A, A288AS, I293V, E297K, E312EG, S322T, D324E  
07BA140676 07BA140676 RTI RTI M41L, M184V, L210W, T215Y  K49R, K122E, I135T, Q145M, S162A, T200A, V245M, A272P, I293V, E297R, Q334N  
07BA140677 07BA140677 RTI RTI T215HY K103N T39N, D123A, I135T, I142IT, S162C, D177E, I178M, V245K, A272P, T286TA, A288S, E297A, K323R, G333D Y56YC 
07BA140678 07BA140678 RTI RTI M41L, L74I, M184V, L210LW, T215Y A98G, K103N, P225H K20R, T39A, E44D, V118VI, K122E, D123N, I135T, I142V, T165L, I178L, T200A, R211RK, F214FL, V245T, V276I, L283I, I293V, E297K, I329L  
07BA140679 07BA140679 RTI RTI M184V  K20R, K49KR, A98S, K122E, D123N, I135T, Q174H, R211K, F214L, V245K, E248D, S251SI, A288S, I293V, E297T, S322T, G333E, Q334H Y271YC 
07BA140680 07BA140680 RTI RTI D67N, T69D, K70KR V106M, G190A M16MT, V35T, T39E, S48ST, E53ED, L109I, K122E, D123NS, I142IV, K173AT, D177E, T200A, Q207N, R211K, V245Q, A272P, E291D, V292I, I329L, G335D  
07BA140681 07BA140681 RTI RTI D67DG, K70KE, M184V, K219KE V179D E6D, K20R, E28A, V35VL, T39TA, V118I, K122E, I135T, T200A, I202V, Q207S, R211K, F214L, K277R, L283I, I293V, P294T  
07BA140682 07BA140682 RTI RTI D67G, K70R, M184V, T215I, K219E L100I, K103N, V108VI K11KR, E28K, K32Q, S48T, K49R, T69N, V90VI, V118I, K122E, I135T, K166R, E169A, K173E, R211K, F214L, L228H, V245E, K249KR, A272P, K277R, A288AT, I293V, E297T, I329L  
07BA140683 07BA140683 RTI RTI   V90VI, A98S, D123E, I135T, D177E, T200E, R211K, V245M, K277R, A288S, I293V, P294T, I329L D110DE 
07BA140684 07BA140684 RTI RTI D67N, K70R, M184V, T215F, K219E Y181C, G190A V35T, E36A, T39E, S48T, K49KR, D123E, I135V, K173T, D177E, T200A, E203K, Q207E, R211K, F214L, L228H, I244V, V245QR, A272P, K277R, R284RK, T286A, E291D, V292I, I293V, E328D, G335D P52PL 
07BA140686 07BA140686 RTI RTI M184V K103N, V108I, V179IL E6D, V35T, K49R, K82R, I135T, S162C, E169D, K173A, Q174K, I178L, T200A, Q207A, R211K, D237DE, V245Q, D250E, A272P, K275KR, T286A, E291D, V292I, I293V, E297T, R307K  
07BA140687 07BA140687 RTI RTI M184V K103N K20KR, K30KR, A62T, D123E, I135T, V179VI, Q197QL, T200I, I202V, L210E, R211K, L228LR, V245E, E248D, I293V, E297K, V317A  
07BA140688 07BA140688 RTI RTI M41L, M184V, T215Y K238T V35E, T39A, K101Q, K122E, I135R, I142IV, S162SN, K166R, I178L, G262GE, A272P, I293V, E297K  
07BA140899 07BA140899 RTI RTI  K103N V35VL, R83RK, K122E, D123DN, T139TA, K173N, Q174QK, D177DG, G196E, T200A, Q207H, R211K, P243H, V245E, A272P, K275R, I293V, E297K, G333E, G335S  
07BA140901 07BA140901 RTI RTI M184V K103N K49R, I135T, E169K, K173E, R211K, V245VI, D250E, A272T, V292I, I293V, E297A, G333E, Q334H  
07BA140902 07BA140902 RTI RTI M184MV  V35T, A158AT, D177E, G196E, T200V, E203ED, P243PS, V245T, D250DG, A272P, K275R, K277KR, Q278N, T286A, I293V, E297Q, D324E  
07BA140904 07BA140904 RTI RTI   E36ED, K49R, V118I, I135T, E169D, G196S, T200A, I202V, E204K, R211G, F214L, V245Q, D250E, A272P, K277R, L283I, I293V, E297K, S322A, I329L, G335GC  
07BA140905 07BA140905 RTI RTI  E138A, V179D, Y188L, G190GA V35M, R83K, D123E, S162C, R211K, A272PS, I274IV, K275R, Q278N, T286A, I293V, D324E, G335D  
07BA140906 07BA140906 RTI RTI  G190A A98S, K173E, L210LS, R211HQ, T215X, A272P, K281KR, T286A, E297R, Q334L  
07BA140908 07BA140908 RTI RTI M184V K103N, P225H P4S, A98S, D123N, I135L, I178L, R211K, F214L, V245MT, A272P, K277R, A288S, V292I, I293V, E297T, I329L, G333E  
07BA140909 07BA140909 RTI RTI M41L, M184V, T215Y K103N, P225H, K238T K20R, I142V, R211K, L283I, T286P, V292I, I293V, E297A, G335S  
07BA140910 07BA140910 RTI RTI  G190A V35I, E44EG, D123E, S162G, Q174H, V179I, G196E, Q197K, T200A, I202V, I293V, E297K, G333E, Q334H  
07BA140911 07BA140911 RTI RTI M41L, M184V  E28A, K122E, D177E, T200TA, R211K, V245E, R284K, I293V, P294T  
07BA140962 07BA140962 RTI RTI M184V K103N, E138A, K238T V35T, K122P, D123E, I135T, S162C, T165L, E169D, K173A, Q174K, D177E, I178L, T200A, Q207K, R211A, V245KQ, E248D, D250X, K277R, L283I, T286A, E291D, V292I, I293V, E297A, Q334QR, G335GE  
07BA140963 07BA140963 RTI RTI M184V Y188L V35T, K101RS, E169D, Q174K, P176Q, I202V, R211K, V245K, A272P, T286A, I329IL, Q334E Q161QR 
07BA141000 07BA141000 RTI RTI D67N, K70R, M184V, T215F, K219Q K103NS, P225H, K238T T39N, I94IL, V118I, D121DY, K122E, D123E, I135V, S162C, E169D, K173A, Q174K, T200TA, Q207E, R211K, F214L, L228H, V245Q  
07BA141010 07BA141010 RTI RTI M41ML, D67N, K70R, M184V, T215F, K219Q K101E, G190S V60VI, A98S, D121HY, K122E, I135T, I202V, R211K, L228H  
07BA141011 07BA141011 RTI RTI M184V  K49KR, K102Q, K122E, D123DN, I135T, S162A, D177E, I178IM, V179I, Q207E, F214L, V245K  
07BA141013 07BA141013 RTI RTI M41L, D67N, L74LI, M184V, L210LW, T215Y K103N, L234LI, K238N K43E, E44A, V90VI, K122E, I135T, I142IV, G196E, T200A, R211Q  
07BA141014 07BA141014 RTI RTI M184V K101E, K103N, E138A, G190A T39L, V60I, S105T, I135T, I142V, S162Y, K166R, K173T, Q174K, T200A, Q207E, R211K, F214L, P243A, V245Q  
07BA141015 07BA141015 RTI RTI   I135T, S162C, T165TI, K166KR, F171Y, Q197E, I202V, Q207D, R211K  
07BA141214 07BA141214 RTI RTI M184MV K103KN K49KR, V118I, K122E, I135T, T165I, I178IL, T200A, F214L, L228H, V245VE, D250E, K281R, L283I, A288AT, V292VI, E297EA, S322A  
07CE140553 07CE140553 RTI RTI M184V K103N, Y188H, H221HY V35I, K82KR, E194ED, G196GE, T200A, I202V, Q207QR, A272P, K275KR, K281R, R284RK, I293V, P294T, E297KR, E328D  
07CE140554 07CE140554 RTI RTI M184V K103N, K238N V35T, E36A, T39D, S48T, K101KQ, I135IMT, K173A, D177E, T200A, R211K, V245Q, A272P, E291D, V317A, D324E, I326V, Q334D, G335D  
07CE140555 07CE140555 RTI RTI M184V E138A K20R, V35T, T39M, V90VI, D123E, I135IT, S162SN, T200A, V245HQ, E248N, R284RK, T286A, I293V, T296TS, E297EA, V317VA, S322AT  
07CE140556 07CE140556 RTI RTI M184V  E28EG, V35M, R83K, K122E, D123E, G196E, T200A, A272P, K281KR, P294T, E297K  
07CE140557 07CE140557 RTI RTI M184V P225H K49R, V60I, A98S, D121Y, K122E, I135T, D177E, Q197QL, T200TA, Q207E, R211K, F214FL, A272P, K277KR, I293V, E297Q, Q334L  
07CE140561 07CE140561 RTI RTI D67DN, K70KR, M184V K103N, V108VI V35VI, G45GE, D123E, I135IL, D177E, R211K, V245M, E248ED, D250E, A272P, I293V, T296TS, E297V  
07CE140562 07CE140562 RTI RTI M184V  V21I, V60I, A98S, D121Y, K122E, I135V, D177E, I178M, T200A, R211K, A272P, I293V, E297R R206RG 
07CE140564 07CE140564 RTI RTI K65R E138A, G190E K20R, A98S, K101Q, D121C, K122E, K173R, D177E, V179G, T200G, E203K, Q207N, R211K, V245E, S251D, A272P, L283I, I293V, E297R, Q334L L92M 
07CE140565 07CE140565 RTI RTI K65R, Y115F, M184V  E6ED, I135T, S162SN, Q197K, T200E, K201R, I202V, V245M, K281R, L325LV  
07CE140566 07CE140566 RTI RTI D67N, K70S, M184V, T215F, K219Q  K11KR, K20KR, V35T, T39M, E53ED, V118I, D123E, I135T, E169D, K173T, Q174K, G196E, T200A, E203K, Q207E, R211K, F214L, V245Q, E248D, A272P, I293V, E297R  
07CE140567 07CE140567 RTI RTI K65KR, M184V K101E, E138A, G190S P9PS, A98AS, V118VI, K122E, I135T, I142V, Q174N, T200A, R211RG, F214L, V245M, A272P, I293V, P294PA, E297A  
07CE140644 07CE140644 RTI RTI   D123E, I135T, F214L, V245T, L283I, V292I, I293V, V317A, S322T, D324E, I329L P52PS 
07CE140646 07CE140646 RTI RTI K70KQ, M184V V179D, Y188L, P225H K20R, V75L, K122E, D123E, I135T, D177E, I178L, F214L, V245Q, A272AP, L283I, I293V, E297V, S322E, I329L, Q334HY  
07CE140649 07CE140649 RTI RTI D67N, K70R, T215FY  K102KR, K122E, I135K, K166R, Q174E, V245E, K277R, L283I, T286A, V292I, I293V, E297A, S322T  
07CE140650 07CE140650 RTI RTI M41L, L74I, M184V, L210W, T215Y A98G V35T, T39L, K102Q, I135V, S162C, E169D, K173A, Q174K, I178L, E203A, Q207E, H208Y, R211K, A272P, K281R, T286A, E297R, I329IV  
07CE140651 07CE140651 RTI RTI A62AV, K70KQ, L74I, M184V K101E, V106VI, Y181YC, G190CST E28K, K32KE, V35M, R83K, S163C, E169D, V179VI, G196E, A272P, K277R, E297R, S322ST, I329L, Q334H  
07CE140652 07CE140652 RTI RTI M184V K103N, V108VI, P225H K20R, K49R, D121DH, V148VG, E169D, K173Q, T200A, E203D, Q207E, R211K, V245I, V292I, I293V, E297A  
07CE140653 07CE140653 RTI RTI A62V, K65R, M184V L100I, K103N V35E, T39A, A98S, D123E, I135R, D177G, G196E, T200A, R211K, V245T, I293V, E297T, Q334L N175ND 
07CE140654 07CE140654 RTI RTI   E6D, K20R, D121Y, K122E, A158S, S162SN, I178M, V179I, T200V, Q207QE, A272P, K277R, K281KR, I293V, Q334L  
07CE140655 07CE140655 RTI RTI M184V K101E, V106M, F227L K20KR, E28EK, V35IM, R83K, D123E, K166R, I178IM, V179VI, I195L, Q207E, R211K, A272P, V276VI, E297R, V317A, I329V, Q334N, G335D  
07CE140659 07CE140659 RTI RTI M41L, M184V, T215F  I31L, T39S, K43E, E44A, A98S, K102Q, V118I, K122E, D123N, I135T, I202V, R211RK, F214L, L228R, T286N, A288S, E297A  
07CE140753 07CE140753 RTI RTI   K122E, D123E, I135T, Q174K, D177E, G196E, I202V, Q207D, R211RK, E248ED, K277KR, K281KR, I293V, S322T, I329V  
07CE140754 07CE140754 RTI RTI M184V K103N, P225H K20R, V60I, A98S, D121Y, K122E, I135T, I142V, D177E, T200S, Q207E, V245E, S251N, A272P, K277R, V292I, I293V, L295LIM, E297R, L303LM, I329IK, Q332E  
07CE140756 07CE140756 RTI RTI M41L, K65KR, M184V, L210W, T215D V106M, V108VI, G190A K20R, V35T, T39M, E40D, V60I, K102KR, K122E, I142V, Q161H, E169D, Q174H, T200A, I202V, V245I, A272P, V292VI, I293V, E297A, I329L F214LM 
07CE140758 07CE140758 RTI RTI M41L, M184V, T215Y  K20KR, V35T, K49R, D123E, S162C, E169D, K173A, Q174K, D177E, I178L, G196GE, T200A, Q207D, R211K, L228R, V245Q, D250E, A272P, R284RK, T286A, E291D, V292I, I293V, E297A, S322T Y115YC 
07CE140760 07CE140760 RTI RTI M41L, M184V, T215Y V106A, G190A, H221Y E28A, V35T, T39A, E44ED, V60VI, S68G, S105T, K122E, I135T, S162C, G196E, T200A, L210LS, R211G, D237E, A272P, T286TA, I293V, E297A, G335D  
07CE140761 07CE140761 RTI RTI D67N, K70R, M184V, K219Q K103N, P225H K20R, V35I, V60I, K101Q, K122E, D123S, I135T, D177DN, I178IM, T200AEV, V245K, A272P, K277R, I293V, E297A  
07CE140762 07CE140762 RTI RTI K65R, K70R, M184V, K219E Y181C V35T, E40D, K49R, V60I, S68G, V90VI, D123E, I135ILM, E169D, I178L, V179I, V189VI, G196D, T200A, I202V, E204D, E248D, A272P, V292I, I293V, I329L  
07CE140764 07CE140764 RTI RTI M41L, D67N, T69D, M184V, L210W, T215Y  V35R, T39AE, K43KQ, E44ED, V60I, V118VI, K122E, D123DN, I135T, I142V, S162SN, D177E, G196GE, T200TA, R211K, V245M, A272P, K277R, I293V, E297A, S322T  
07CE140765 07CE140765 RTI RTI   E28K, K32E, V35T, T39A, E40D, K43R, V60I, I135V, S162A, K173A, Q174K, D177E, I178M, T200A, K201Q, E204EG, Q207E, V245E, K249R, A272P, V276I, K281R, T286A, E291D, I293V, P294T, S322T, G335D  
07CE140766 07CE140766 RTI RTI   E6ED, K20R, S68G, T69N, E79D, I135T, R211RK, V245M, A272P, I293V, E297AV, D324E  
07CE140786 07CE140786 RTI RTI   V21I, V60I, A98S, K122E, D123DN, I142IT, E169D, D177E, I195V, Q197P, T200A, Q207K, R211T, V245E, K249R, A272P, V276VI, K277KR, T286A, I293V, E297R, Q334E  
07CE140787 07CE140787 RTI RTI   E6D, K102R, K122E, I142V, G196E, R211K, V245K, A288S, I293V, E297A, Q334L  
07CE140788 07CE140788 RTI RTI A62V, K70R, M184V, K219Q K103N, Y188L T69N, K102R, D123E, I135T, S162Y, Q174N, T200A, I202V, F214L, L228R, V245M, D250E, A272P, V276T, K277R, I293V, L310I, S322L, G335D K323I 
07CE140791 07CE140791 RTI RTI   T39TI, K102Q, D123E, I142T, S162SN, I202V, E204EK, R211K, D237DN, G262GE, A272P, K277KR, I293V, E297A, S322T, I329V, Q334R, G335D  
07CE140918 07CE140918 RTI RTI T215D  E6ED, E28A, V35E, T39TA, K49R, E53D, V60I, S68G, A98S, D121Y, K122E, D123DE, I135T, D177E, I178M, T200AE, E204EK, Q207DE, L210LF, R211K, V241X, A272P, T286A, V292VI, I293IV, T296S, E297K, A304E, K311R, S322ST, G333GDE, Q334QL  
07CE140921 07CE140921 RTI RTI M41L, L74I, V75A, M184V, L210W, T215Y K103N, P225H K20R, E44D, K101Q, K122E, D123N, D177DN, T200L, L228H, I244IV, V245VLM, E248ED, D250DE, A272P, A288S, I293V, E297EQ  
07CE140923 07CE140923 RTI RTI M184V  K122E, I135T, I142IT, S162SC, E169D, T200TA, F214FL, V245I, I257IT, A272P, I293V, E297R, L301I, S322T, D324E, I329L, Q334P, G335D  
07CE140924 07CE140924 RTI RTI   K11KR, V60I, A98S, K122E, D123DG, K166KR, D177E, G196V, Q197QH, T200A, Q207E, R211RK, V245VE, A272P, K277R, I293V, E297K, S322T, I329V  
07CE140928 07CE140928 RTI RTI M184V  K102Q, D123E, I135T, D177E, E203EG, A272P, K277R, L283I, T286A, I293V  
07CE140929 07CE140929 RTI RTI   K64KR, D121Y, K122E, S162A, V179T, L228I, V245L, A272P, K277R, Q278H, T286A, I293V, D324E  
07CE140930 07CE140930 RTI RTI   V21I, V35T, T39L, V60I, D123E, K173A, Q174K, G196E, Q207E, R211K, F214FL, V245Q, E248D, A272P, G273R, Q278HY, E297K, K311R, Q334G, G335D  
07CE140986 07CE140986 RTI RTI A62V, K65R, Y115YF, M184V A98G, K101E, Y181YC, G190S E28K, K32E, V35VIM, K122E, I135L, V179VI, R211K, I244V, V245E, A272P, I293IV, E297T, K311KR, S322T, I329L E224EQ 
07CE140987 07CE140987 RTI RTI A62V, M184V V106A, E138A, H221Y, F227L K20R, D123E, S162N, T165I, D177E, I202V, R211K, F214L, I293V, P294A, Q334L  
07CE140990 07CE140990 RTI RTI   D121H, K122E, I135T, D177E, F214L  
07CE140991 07CE140991 RTI RTI K65KR, L74LV, M184I L100I, K103N V60VI, A98S, D121CY, K122E, I178M, T200A, E203K, Q207E, R211K, V245E  
07CE141220 07CE141220 RTI RTI M41L, M184V, L210W, T215Y K103N D121H, K122E, I135T, I142V, T200KR, K201M, V245K, K249Q, D250DN, L283I, I293V, E297A, S322A  
07CE141227 07CE141227 RTI RTI  V179D K20R, V90VI, K122P, D123E, I135T, D177DE, G196E, Q207QE, R211RK, F214L, K277R, I293V, E297DN, V317A  
07CE141232 07CE141232 RTI RTI   K122KE, I135T, R211K, F214FL, K249Q, A288S, I293IV, E297A, Q334L  
07PI140419 07PI140419 RTI RTI   S48T, K49R, V60VI, T69AS, D121H, K122E, I135T, I142V, K166R, D177E, T200AV, Q207X, R211K, E248ED, A272P, K277R, L283I, I293V, P294T, I329V, Q334N  
07PI140424 07PI140424 RTI RTI M41ML, V75VM, M184V, T215F K101E, G190S E6EK, E28K, K32E, V60VI, W88C, A98S, K122E, I142V, V189VI, R211K, V245Q, A272S, T286A, I293V, I326V, I329V, Q334G  
07PI140695 07PI140695 RTI RTI   D123E, I159IV, S162C, E169D, D177E, R211RK, V245K, A272P, I293V, Q334N, G335D  
07PI140696 07PI140696 RTI RTI   V35T, I135V, S162C, R211K, V245Q, D250E, A272P, K277R, T286A, E291D, V292I, E298EG, K311R, Q334QH, G335D  
07PI140697 07PI140697 RTI RTI   K20KR, K22R, V35T, E36A, T39E, S48T, K122E, I135T, T139TI, I142IM, S162Y, K173A, Q174K, T200A, E224D, V245Q, D250E, A272P, I274IV, K275KQ, Q278QH, K281R, T286A, E291D, V292I, I293V, D324DE, G335D  
07PI140698 07PI140698 RTI RTI M41L, A62V, L74I, M184V, L210W, T215Y A98G, K103N, G190GA, Y318YF K20KR, K32R, K43E, E44A, I94L, K102Q, V111I, I135IL, E169D, I178L, H208Y, R211RK, L228R, A272P, K277R, E297A R206RI 
07PI140700 07PI140700 RTI RTI   K122KE, S162C, I178L, T200TA, Q207H, R211K, A272P, K277R, I293IV, P294Q, G333E, Q334N, G335S  
07PI140701 07PI140701 RTI RTI  V106I, G190GE V35VI, D121H, K122E, I135IT, A158S, K173Q, G196GE, Q197K, I202V, R211RKQ, V245VA, A272AP, K277R, T286TA, V292VI, I293V, E297A, S322A, Q334Y  
07PI140702 07PI140702 RTI RTI M184V E138A K20KR, V60VI, K101Q, K122E, I142V, D177N, G196E, D237N, V245I, A272P, K277KR, A288S, I293V, P294PS, I326IT  
07PI140703 07PI140703 RTI RTI M41L, M184V, T215F K103N K49KR, S68G, D123E, T139K, V179I, T200A, H208HY, R211K, A272P, I293V, L295F, E297K, S322SA, E328D, G333E  
07PI140704 07PI140704 RTI RTI M184V K103N, E138A V35E, T39A, E79D, K101Q, I142V, S162C, K173R, Q174E, T200A, V292I, I293V, E297K, S322T, I329L, G335S  
07PI140705 07PI140705 RTI RTI   K122E, D123S, I135T, K154KR, K173T, D177E, I180V, R211K, I293V, P294T, E297K, L301M, K311R  
07PI140715 07PI140715 RTI RTI D67DN, M184V K103S, G190S, K238T V35I, D123E, I135T, S162C, R211K, V245T, T286P, I293V, E297KR, S322T, D324E, I329L