Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Bhusal (2016)
Title Prevalence of HIV-1 Subtypes and Antiretroviral Drug Resistance Mutations in Nepal.
Citation Curr HIV Res
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 35
NumPts 35
Subtype C, D

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
11NP003/2011 11NP003/2011 None None   V35T, T39N, S48T, V60I, K122E, K173A, Q174K, D177E, Q197K, T200A, Q207D, R211K, V245Q, A272P, K275R, K277R, E291D, V292I, I293V, V317A, G335D  
11NP004 11NP004 AZT, 3TC NVP   V35T, T39N, S48T, V60I, K122E, K173A, Q174K, T200A, Q207E, K238R, V245E, A272P, K277R, T286A, E291D, V292I, I293V, L301F, G335D, R356K, M357R, G359T, T377M, K390R, A400T, E404D, E432D, V435A, A437V, V466I, D471E, H483Y, L491S, S519N, K530R, A534S, A554S L193S 
11NP007/2011 11NP007/2011 AZT, 3TC NVP   V35T, E36A, T39E, S48T, V60I, D121H, K122E, I135V, K173A, Q174K, D177E, T200TAS, I202V, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, V317T, Q334H, G335D  
11NP008/2011 11NP008/2011 None None   V35T, T39D, S48T, V60I, K101R, K103R, K122E, I135V, T139A, K166R, K173A, T200A, Q207E, R211K, V245Q, A272P, L283I, E291D, V292I, I293V, G335D K102D 
11NP010/2011 11NP010/2011 AZT, 3TC NVP   V35T, E36A, T39D, V60I, K102Q, D121Y, K122E, D123N, S162A, K173A, D177E, I178L, T200A, E204K, Q207E, V245Q, A272P, K277R, L283I, K287R, E291D, V292I, I293V, P294T, V317A, I329V, G335E  
11NP014 11NP014 AZT, 3TC NVP   V35T, T39E, S48T, V60I, K102Q, D121H, K122E, I135R, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, A272P, L283I, T286A, E291D, V292I, G335D, R356K, G359T, T377M, K390R, A400T, E404D, E432D, V435A, A446S, N447S, V466I, S468T, T470A, D471E, H483C, L491S, S519N, K530R, A534S, A554S  
11NP015/2011 11NP015/2011 None None   V8I, V35T, E36A, T39D, S48T, V60I, D121H, K122E, I135R, S162C, K173T, D177E, I178L, L193F, T200A, Q207E, R211K, V245Q, A272P, E291D, V292I, I293V, E297A, D324E, I329L  
11NP016 11NP016 AZT, 3TC NVP   V8I, V35T, T39D, S48T, V60I, T69I, K102R, D121Y, K122E, I135R, K173A, Q174K, T200A, I202V, Q207A, V245Q, A272P, T286A, V292I, I293V, D324E, G335D, R356K, G359T, A376T, T377M, K390R, A400T, T403S, E404D, E432D, V435A, A437V, D460N, V466I, D471E, L491S, S519N, K530R, A534S, A554S, K558R  
11NP028/2011 11NP028/2011 AZT, 3TC NVP   I31L, V35T, T39E, V60I, K122E, D123S, A158S, K173T, Q174K, D177E, I178M, T200A, Q207G, R211K, V245Q, A272P, K277R, K281R, E291D, I293V, D324DE, I326V, Q334D  
11NP035/2011 11NP035/2011 3TC, D4T EFV   V35T, T39D, S48T, V60I, D121Y, K122E, I135T, S162A, K173T, D177E, I178M, T200A, Q207D, R211K, V245Q, A272P, V276T, K277R, T286A, E291D, V292I, I293V, L310I, G335E  
11NP041/2011 11NP041/2011 AZT, 3TC NVP   V35T, E36A, T39E, S48T, V60I, K102R, D121H, K122E, K173A, Q174K, D177E, T200A, I202V, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, V317A, D324E, G335D  
11NP046 11NP046 None None   K20R, V35M, E36A, T39D, S48T, V60I, D121Y, K122E, T139K, K166R, K173A, D177E, T200A, Q207E, R211K, V245Q, I270V, A272P, K277R  
11NP051/2011 11NP051/2011 None None   E29K, V35T, T39N, S48T, V60I, K102R, D121Y, K122E, S162A, K173A, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, L310I, D324E, G335D  
11NP065/2011 11NP065/2011 AZT, 3TC NVP   V35T, T39N, S48T, V60I, K101R, D121Y, K122E, S162A, K166R, K173T, D177E, T200A, Q207E, R211K, P243L, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, P313T, G335D I202N 
11NP068 11NP068 AZT, 3TC NVP  E138A V35T, E36A, T39D, S48T, V60I, K102Q, K104R, D121Y, K122E, I135T, S162A, K173A, Q174R, D177E, T200A, Q207A, V245Q, A272P, K277R  
11NP069 11NP069 None None   T27S, V35T, T39D, S48T, V60I, D121Y, K122E, I135R, S162A, K173T, D177E, T200A, Q207E, R211K, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293V, V317A, D324E, G335D  
11NP071/2011 11NP071/2011 AZT, 3TC NVP  V179D V35T, E36A, T39D, S48T, V60I, K102Q, D121Y, K122E, K166R, K173A, D177K, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, V317A, D324E, G335D M41K 
11NP074 11NP074 None None   V35T, T39N, S48T, V60I, D121Y, K122E, K166R, K173A, I178L, T200A, Q207G, R211K, V245Q, A272P, K277R  
11NP075 11NP075 None None   V8I, V35T, E36A, T39E, S48T, V60I, I135L, S162N, K166R, K173A, Q174R, D177E, T200A, Q207E, V245Q, A272P, K277R  
11NP076/2011 11NP076/2011 AZT, 3TC NVP   K32E, V35T, E36A, T39E, V60I, D121Y, K122E, I135K, K166R, K173A, D177E, T200A, Q207N, R211K, V245Q, A272P, T286A, E291D, V292I, I293V, E297T, V314M, V317A, I329L  
11NP079 11NP079 None None   V35T, E36A, T39D, V60I, K102E, D121Y, K122E, I142V, K166R, K173A, D177E, Q207E, V245Q, E248Q, A272P, T286A, E291D, V292I, I293V, A304E, K311R, I329V, G335D, P345Q, F346L, M357R, G359T, T377M, K390R, A400T, E404D, V435A, L491S, I506V, S519N, K527R, A554S F87S 
11NP080 11NP080 None None   V35T, E36A, T39D, S48T, V60I, D121Y, K122E, I135R, S162A, K173A, Q174R, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R  
11NP082 11NP082 AZT, 3TC NVP   V35T, E36A, T39D, S48T, V60I, D121Y, K122E, I135V, S162A, K173A, D177E, T200A, E204K, Q207E, V245Q, I257L, A272P, K277R  
11NP084 11NP084 None None   V35T, E36A, T39E, S48T, D121Y, K122E, I135T, K173A, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, E297A, Q334H, G335D, R356K, M357R, G359T, T377M, K390R, A400T, E404D, V435A, D471E, T477A, H483Y, L491S, S519N, K527N, K530R, A534S, A554S A437E 
11NP086 11NP086 AZT, 3TC NVP   V35T, T39N, V60I, T69I, D121Y, K122E, T165K, K166R, K173A, V179I, Q197E, T200A, Q207E, R211K, V245Q, D250E, A272P, K277R, T286A, E291D, V292I, I293V, P294T, E312D, P321S, G335D, M357R, G359S, A360T, T369A, T377M, K390R, A400T, E404D, E432D, V435A, K454R, D460N, V466I, D471E, H483Y, L491S, S519N, K527Q, K530R, A534S, A554N  
11NP091 11NP091 None None   V35T, T39N, S48T, V60I, K122E, K173A, Q174K, D177E, T200A, Q207D, V245Q, A272P, K275R, K277R, E291D, V292I, I293V, V317A, G335D, R356K, G359A, T377M, K390R, A400T, E404D, V435A, E449D, V466I, D471E, L491S, S519N, A534S, A554S, K558R  
11NP092 11NP092 AZT, 3TC NVP   V35T, T39N, S48T, V60I, K101R, D121Y, K122E, S162A, K166R, K173T, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R  
11NP093 11NP093 None None   V8I, V35T, E36A, T39D, S48T, V60I, D121Y, K122E, I135K, S162C, K166R, K173A, D177E, T200A, Q207E, R211K, V245Q, A272P, K275R  
11NP095 11NP095 AZT, 3TC NVP   V35T, E36A, T39D, S48T, V60I, D121H, K122E, I135T, K173T, Q174R, D177E, T200A, Q207E, R211K, V245Q, A272P  
11NP102/2011 11NP102/2011 AZT, 3TC NVP   V35T, E36A, T39D, S48T, V60I, D121Y, K122E, K166R, K173T, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, K281R, T286A, E291D, V292I, I293V, E297A, G335D  
11NP103/2011 11NP103/2011 AZT, 3TC NVP   V35T, E36A, T39D, S48T, V60I, K102R, K103R, Q174K, D177E, T200E, Q207E, V245Q, A272P, V276I, K277R, L283I, V292I, I293V, V317A, G335D  
11NP104/2011 11NP104/2011 None None   V35T, E36A, T39D, S48T, V60I, D121Y, K122E, D123E, I135R, S162H, K173A, D177E, T200A, Q207G, R211K, V245Q, A272P, K281R, E291D, V292I, I293V, E297K, P313PS, I326V, Q334X, G335D  
11NP107/2011 11NP107/2011 AZT, 3TC NVP   T27S, V35T, E36A, T39D, S48T, V60I, D121Y, K122E, I135R, S162H, K173A, D177E, T200A, Q207E, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, Q334Y, G335D  
11NP115 11NP115 3TC, D4T EFV   V35T, T39D, V60I, K102R, D121H, K122E, I135R, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, Q334H, G335D, R356K, G359T, T377M, K390R, A400T, E404D, E432D, V435T, K454R, V466I, V467I, D471E, H483Y, L491S, S519N, A554S  
11NP122/2011 11NP122/2011 None None   E28K, E29K, V35T, T39N, S48T, V60I, K122E, D123S, K173T, D177E, I178M, T200A, Q207N, R211K, V245Q, A272P, K277R, K281R, E291D, I293V, E297K, V317A, Q334L E298R, A299Q