Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Lockman (2012)
Title Nevirapine- versus lopinavir/ritonavir-based initial therapy for HIV-1 infection among women in Africa: a randomized trial.
Citation PLoS Med
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 463
NumPts 414
Subtype C, A, D, B, CRF35_AD, CRF21_A2D, G

 

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Page 1   listing Isolate 1 to Isolate 100 from Total 463 Clinical PR Isolates


SubjectIsolatePIsWksPIMajorPIMinorCommonUnusual
PT1 PT1 _D0 None  L90LM  L10M, T12S, K14KR, L19I, M36I, R41K, L63Q, H69K, I93L  
  PT1 _D336 LPV 48 L90M  L10M, T12S, L19I, M36I, R41K, L63Q, H69K, I93L, N98S  
PT10 PT10 _D0 None    I15V, M36IV, R41K, L63AS, H69K, V82I, I93L  
PT11 PT11 _D0 None    I13V, I15V, E35D, M36I, N37D, R41K, K43KR, R57K, D60E, H69K, L89M  
PT12 PT12 _D0 None    L10LIV, M36I, N37S, R41K, I62V, L63T, I64IM, E65ED  
PT13 PT13 _D0 None    T12S, I15V, L19I, M36I, R41K, D60E, H69K, L89M, I93L  
PT14 PT14 _D0 None    T12S, I15V, L19I, M36I, R41K, K45R, L63P, C67Y, H69K, I93L  
PT15 PT15 _D0 None    T12S, I15V, L19I, M36I, N37D, R41RK, Q61QE, I62IV, L63X, I64IM, H69K, V82VI, L89M, I93FL  
PT16 PT16 _D0 None    T12S, I15V, L19I, E35D, M36I, L63V, H69K, T74S, L89M, I93L  
PT17 PT17 _D0 None    T12S, I13V, I15V, L19I, K20R, M36I, R41K, H69K, T74S, L89M, I93L  
PT18 PT18 _D0 None    T12PS, G16E, L19I, D60E, L63AS, H69K, L89M, I93L  
PT19 PT19 _D0 None    I15V, L19V, M36I, R41K, L63V, H69K, T74S, L89M, I93L  
PT2 PT2 _D0 None    T12S, I15IV, G16E, L19I, H69K, V77I, L89M, I93L  
PT20 PT20 _D0 None    K14KR, I15V, L19I, M36IT, N37D, R41K, L63Q, H69K, T74A, L89M, I93L  
PT21 PT21 _D0 None    T12S, I15V, L19I, R41K, L63V, I64L, H69K, V77I, L89M, I93L  
PT22 PT22 _D0 None    L10V, I13V, K14R, I15IV, G16E, E35D, M36I, R41K, K45R, R57K, L63LV, H69K, L89M  
PT23 PT23 _D0 None    T12TS, I15V, L19IT, E35D, M36I, R41K, K45KR, D60DE, Q61QE, L63S, H69K, I93L T26TI 
PT24 PT24 _D0 None    T12S, G17D, L19I, K20KR, M36I, N37K, R41K, Q61E, H69K, L89M, I93L  
PT25 PT25 _D0 None    T12S, L19I, K20R, M36I, R41K, H69K, I72ILM, L89M, I93L  
PT26 PT26 _D0 None    T12X, I15V, L19LI, M36MI, R41RK, L63X, H69K, K70KR, T74TS, V77VI, L89M, I93L  
PT27 PT27 _D0 None    T12AP, I15V, G16E, L19I, K20R, M36I, P39S, I62V, L63P, H69K, L89LM, I93L  
  PT27 _D336 None    T12TAS, I15IV, G16E, L19LI, K20R, M36I, P39S, I62V, L63P, H69K, L89LM, I93L  
PT28 PT28 _D0 None    T12TAS, I15IV, L19I, M36I, R41K, L63A, H69K, I93L  
PT29 PT29 _D0 None    T12S, I15V, L19I, M36I, N37S, R41K, L63P, H69KN, I72IM, L89M, I93L  
PT3 PT3 _D0 None    T12S, I15V, L19I, M36I, R41K, D60E, H69K, L89M, I93L  
PT30 PT30 _D0 None    L10I, I13V, I15V, R41K, L63PQ, I64IV, H69KN  
PT31 PT31 _D0 None    T12S, I15V, L19I, M36I, N37NS, R41K, H69K, L89M, I93L  
PT32 PT32 _D84 LPV 12   I13V, M36I, R41K, I64V  
PT33 PT33 _D84 None    I15V, L19LI, M36I, R41K, H69K, L89M, I93L P44PS 
PT34 PT34 _D0 None    T12TA, I13V, K14KR, E35D, M36I, R41K, K45R, R57K, L63P, H69K, K70KR, L89M, I93IM  
PT35 PT35 _D0 None    L10LV, T12TA, I15IV, L19I, M36I, R41K, L63V, H69K, T74S, L89M, I93L  
PT36 PT36 _D339 LPV 48   L10V, I13V, I15V, G16E, E35DG, M36I, R41K, K45R, R57K, L63S, H69K, K70R, L89M  
PT37 PT37 _D0 None    T12S, K14R, I15V, L19I, M36I, R41K, L63AS, H69K, L89LM, I93L  
PT38 PT38 _D0 None    I15V, M36L, R41K, K45KR, D60E, Q61DH, I62V, L63PS, I64M, H69K, K70KR, I72IV, L89M, I93L  
PT39 PT39 _D0 None    T12S, I15V, L19I, M36I, R41K, L63A, H69K, I93L  
PT4 PT4 _D0 None    L10V, I13V, G16E, K20R, E35D, M36I, P39PT, R57K, L63V, H69K, L89M  
PT40 PT40 _D0 None    T12S, I15V, L19X, E21EQ, M36I, R41K, H69K, K70KR, L89M, I93L  
PT41 PT41 _D0 None    L10LI, I15V, M36I, N37K, R41N, L63X, I64IV, H69K, V82I, I93L  
  PT41 _D78 None    L10LI, I15V, M36I, N37K, R41N, L63X, H69K, V82I, I93L  
PT42 PT42 _D0 None    I13V, K14KR, E35D, M36I, R41K, R57K, L63P, H69K, K70KR, L89M  
PT43 PT43 _D0 None    I15V, L19IT, M36I, R41K, L63T, E65D, H69K, I72IV, L89LM, I93L  
  PT43 _D421 LPV 60   I15V, L19T, M36I, R41K, L63T, E65D, H69K, I93L  
PT44 PT44 _D0 None    T12S, I15V, L19I, M36I, R41K, H69K, L89M, I93L  
PT45 PT45 _D0 None    V11VI, T12S, I15V, L19V, M36I, R41K, D60E, Q61E, L63P, H69K, I85IV, L89M, I93L  
PT46 PT46 _D0 None    T12S, I15V, L19T, K20R, M36I, P39A, R41K, L63Q, H69K, L89M, I93L  
PT47 PT47 _D0 None    T12S, I15V, L19I, E35ED, M36I, R41K, L63P, H69K, I93L  
PT48 PT48 _D252 LPV 36   L10LV, I13IV, A22AV, E35D, M36I, R41K, R57K, I62V, L63S, I64M, H69K, L89M  
PT49 PT49 _D0 None    T12S, L19I, E35D, M36I, R41K, L63T, H69K, T74S, L89M, I93L  
PT5 PT5 _D0 None    L10V, T12S, I15V, L19I, M36I, R41K, I62V, L63P, I64L, H69K, A71T, L89M, I93L  
  PT5 _D84 None    L10V, T12S, I15IV, L19I, M36I, R41K, I62V, L63P, I64L, H69K, A71T, L89M, I93L  
PT50 PT50 _D-16 None    I15IV, L19I, M36I, L63S, H69K, L89M, I93L  
  PT50 _D504 None    I15V, L19I, M36I, L63S, H69K, L89M, I93L  
PT51 PT51 _D0 None    T12S, I15V, G17D, L19I, M36I, N37K, R41K, L63P, H69K, I93L  
PT52 PT52 _D0 None    T12S, I15V, L19I, M36I, R41K, Q61E, H69K, T74S, L89M, I93L  
  PT52 _D336 None    T12S, I15V, L19I, M36I, R41K, Q61EK, H69K, T74S, L89M, I93L  
PT53 PT53 _D288 None    T12TS, I15V, L19I, E21EK, N37S, R41K, L63P, H69KQ, V77I, L89LM, I93L  
PT54 PT54 _D0 None    T12TS, I15V, L19V, M36I, R41K, L63LP, H69K, K70Q, L89M, I93L  
PT55 PT55 _D0 None    L10LI, T12TS, L19I, M36I, R41K, L63T, H69K, L89M, I93L  
PT56 PT56 _D0 None    I15V, G16A, L19LI, E35D, M36MI, N37X, R41K, H69K, L89M, I93L  
PT57 PT57 _D0 None    I15V, L19IV, M36I, R41K, K45R, L63X, H69K, L89M, I93L  
PT58 PT58 _D-20 None    T12S, I15IV, L19I, K20R, E35D, M36I, R41K, L63P, H69K, I72E, I93L  
PT59 PT59 _D0 None    T12S, L19I, M36I, R41K, D60E, Q61E, I62V, L63P, H69K, L89M, I93L  
PT6 PT6 _D0 None    T12S, I15V, L19I, D25E, E35D, M36I, N37D, R41K, D60E, Q61E, L63P, H69K, I93L  
PT60 PT60 _D0 None    T12S, I15V, L19T, E35D, M36I, R41K, K45R, R57RK, D60E, L63S, H69K, V82I, L89M, I93L  
  PT60 _D504 LPV 72   T12S, I15V, L19T, E35D, M36I, R41K, K45R, R57RK, D60E, L63S, H69K, V82I, L89M, I93L  
PT61 PT61 _D0 None    K14KR, I15V, L19I, M36I, R41K, H69K, L89M, I93L  
PT62 PT62 _D0 None    I13V, G16E, M36I, R41K, K45KR, K55KN, I64V, H69Y, I72T  
PT63 PT63 _D0 None    T12PS, I15V, L19X, E35D, M36I, Q61QE, L63T, I64IL, H69K, V82I, L89M, I93L  
PT64 PT64 _D0 None    L10V, I13V, I15V, E35D, M36I, R41K, K45R, R57K, L63PS, H69K, L89M  
PT65 PT65 _D0 None    I15V, K20R, M36I, N37S, L63V, H69K, V75I, L89M, I93L R41D 
PT66 PT66 _D0 None    T12S, I15V, L19IV, M36I, R41K, L63Q, H69K, L89M, I93L  
PT67 PT67 _D0 None    I13V, E35D, M36I, N37D, R57K, L63P, H69K, K70KR, L89M  
PT68 PT68 _D0 None    K14R, I15IV, R41K, L63P, H69Q, V77VI  
PT69 PT69 _D0 None    L19I, M36I, R41K, L63Q, I64V  
PT7 PT7 _D0 None    T12S, I15V, L19I, M36I, R41K, L63P, H69K, I85IV, I93L  
PT70 PT70 _D0 None    T12S, K14T, L19IV, K20R, M36I, R41K, D60E, Q61H, I62IV, L63PS, I64IL, H69K, L89M, I93L  
PT71 PT71 _D0 None    T12S, I15V, L19I, M36I, N37S, R41K, L63PS, H69K, K70KR, L89M, I93L  
PT72 PT72 _D0 None    T12S, I15V, L19I, M36I, N37A, R41K, L63LP, H69K, L89M, I93L  
PT73 PT73 _D-1 None    I13V, K14R, K20R, E35D, M36I, N37D, R41K, K45R, Q61QE, H69K, K70KR, L89M  
PT74 PT74 _D0 None    K14R, I15V, L19I, M36I, R41K, H69K, L89M, I93L  
PT75 PT75 _D0 None    T12S, I15V, L19I, E35D, M36I, R41K, D60E, H69K, L89M, I93L  
PT76 PT76 _D0 None    T12S, I15IV, L19I, M36I, R41K, L63X, H69K, T74S, L89M, I93L  
PT77 PT77 _D0 None    L19T, K20R, M36I, R41K, H69K, L89M, I93L  
  PT77 _D602 LPV 86   L19T, K20R, M36I, R41K, H69K, L89M, I93L  
PT78 PT78 _D0 None    T12S, I15V, L19I, M36I, R41K, D60E, L63P, H69K, L89M, I93L  
PT79 PT79 _D0 None    I15V, L19I, R41K, H69K, V77I, L89M, I93L  
PT8 PT8 _D0 None    I13V, K14KR, G16E, K20R, E35D, M36I, R41RK, L63T, G68E, H69KR, L89IM, T91V, I93L  
PT80 PT80 _D0 None    T12S, K14I, I15V, L19I, M36I, R41K, D60E, L63V, H69K, L89M, I93L  
PT81 PT81 _D0 None    V11VI, T12S, I15V, L19I, M36I, R41K, L63P, H69K, L89LM, I93L  
PT82 PT82 _D162 LPV 17   K14I, I15V, L19V, M36I, R41RK, L63I, H69K, L89M, I93L  
PT83 PT83 _D0 None    I15V, G16E, K20KR, M36I, P39PS, R41RK, I72IR  
PT84 PT84 _D0 None    I15V, L19X, K20KR, M36I, N37X, R41K, K43R, V82VI  
PT85 PT85 _D0 None    I13IV, E35D, M36I, R41K, R57K, L63P, H69K, V77VI, R87RK, L89LM  
PT86 PT86 _D0 None    T12S, I15V, L19I, M36I, N37NS, R41K, H69K, L89M, I93L  
PT87 PT87 _D0 None    L10LI, I13V, G16GE, K20R, E35D, M36I, R41K, R57K, L63X, H69K, L89M  
PT88 PT88 _D0 None    T12TS, I15V, L19IT, N37X, R41K, K43KR, L63P, H69K, V77I, L89M, I93L  
PT89 PT89 _D0 None    I15V, L19I, M36I, N37NS, R41K, L63A, H69K, I93L  
PT9 PT9 _D0 None    I13V, R41K, L63P, H69Y  
PT90 PT90 _D0 None    L10I, T12A, I13V, K14R, I15V, E35D, M36I, R41K, K45R, R57K, L63IV, H69K, L89M  
PT91 PT91 _D0 None    T12S, I15V, L19I, M36I, R41K, D60E, L63P, H69K, I72IM, L89M, I93L