Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Misbah (2016)
Title Comparative analysis of drug resistance mutations in the human immunodeficiency virus reverse transcriptase gene in patients who are non-responsive, responsive and naive to antiretroviral therapy.
Citation Arch Virol
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 102
NumPts 102
Subtype C, A

 

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Page 1   listing Isolate 1 to Isolate 100 from Total 102 Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
IN.HNR.RT2-10 IN.HNR.RT2-10 RTI RTI   V35T, T39N, S48T, V60I, D121H, K122E, I135R, S162C, K173T, Q174K, D177E, T200A, Q207E, R211K  
IN.HNR.RT2-11 IN.HNR.RT2-11 RTI RTI M184V Y181C V35T, E36A, T39E, S48T, K49R, V60I, D121Y, K122E, I135V, D177E, I178M, T200A, Q207E  
IN.HNR.RT2-12 IN.HNR.RT2-12 RTI RTI   V35T, E36A, T39D, S48T, V60I, K122E, D123S, K166R, K173A, Q174K, D177E, T200A, E203D, Q207A  
IN.HNR.RT2-13 IN.HNR.RT2-13 RTI RTI   V35T, T39N, V60I, D121Y, K122E, K173A, Q174R, D177E, T200A, Q207E, R211K  
IN.HNR.RT2-14 IN.HNR.RT2-14 RTI RTI   V35T, E36A, T39D, S48T, V60I, D121Y, K122E, I135T, T165I, K173A, Q174R, D177E, I178L, T200A, Q207K, R211K  
IN.HNR.RT2-15 IN.HNR.RT2-15 RTI RTI   V35T, T39D, S48T, E53D, V60I, D121H, K122E, S162H, K166R, K173T, D177E, T200A, Q207A, R211K  
IN.HNR.RT2-16 IN.HNR.RT2-16 RTI RTI   V35T, E36A, T39D, V60I, D121Y, K122E, I135V, K173V, Q174R, D177E, I178L, T200V, Q207E, R211K  
IN.HNR.RT2-17 IN.HNR.RT2-17 RTI RTI   V35T, E36A, T39D, S48T, V60I, D121H, K122E, I135V, S162A, K173A, D177E, T200A, Q207R, R211K  
IN.HNR.RT2-18 IN.HNR.RT2-18 RTI RTI   V35T, T39D, S48T, V60I, D123E, I135R, K173A, D177E, T200A, Q207E, R211T  
IN.HNR.RT2-19 IN.HNR.RT2-19 RTI RTI   K32E, V35T, E36A, T39D, S48T, V60I, K122E, D123S, I135R, K173A, T200A, Q207E, R211K  
IN.HNR.RT2-20 IN.HNR.RT2-20 RTI RTI   V35T, T39E, S48T, V60I, D121H, K122E, I135R, K173A, D177E, T200A, Q207E, R211K  
IN.HNR.RT2-21 IN.HNR.RT2-21 RTI RTI   V35T, T39E, V60I, D121Y, K122E, I135R, I142T, K166R, K173A, D177E, I178L, T200A, Q207K, R211K, F214L  
IN.HNR.RT2-22 IN.HNR.RT2-22 RTI RTI   V35T, T39E, V60I, D121Y, K122E, I135R, I142T, K166R, K173A, D177E, I178L, T200A, Q207K, R211K, F214L  
IN.HNR.RT2-23 IN.HNR.RT2-23 RTI RTI   V35T, E36A, T39D, S48T, V60I, D121H, K122E, I135R, S162A, K173T, D177E, I178L, T200A, Q207E  
IN.HNR.RT2-24 IN.HNR.RT2-24 RTI RTI   V35T, T39D, S48T, V60I, K122E, I135V, Y146S, K166R, K173A, D177E, G196R, T200A, I202V, Q207E, R211K  
IN.HNR.RT2-25 IN.HNR.RT2-25 RTI RTI M41L, M184V K103N, E138Q V35T, T39E, E44D, V60I, A98S, D121H, K122E, I135T, S162C, K173T, Q174R, D177E, T200A, I202V, Q207E, R211K  
IN.HNR.RT2-26 IN.HNR.RT2-26 RTI RTI   V35T, E36A, T39D, S48T, V60I, K122E, D123S, K166R, K173A, D177E, T200A, Q207E  
IN.HNR.RT2-27 IN.HNR.RT2-27 RTI RTI M41L  V35T, E36A, T39D, V60I, D121Y, K122E, S162C, K166R, K173A, Q174R, D177E, I178L, T200A, Q207E, R211K  
IN.HNR.RT2-28 IN.HNR.RT2-28 RTI RTI   V35T, E36A, T39E, S48T, V60I, K122E, I135T, K173A, D177E, E194D, T200A, Q207E  
IN.HNR.RT2-29 IN.HNR.RT2-29 RTI RTI   V35T, T39D, S48T, V60I, D121Y, K122E, I135R, S162A, K173A, D177E, Q197K, T200A, Q207E  
IN.HNR.RT2-30 IN.HNR.RT2-30 RTI RTI   V35T, T39D, S48T, E53D, V60I, D121H, K122E, S162H, K166R, K173T, D177E, T200A, Q207N, R211K  
IN.HNR.RT2-4 IN.HNR.RT2-4 RTI RTI   V35T, T39E, S48T, V60I, K101R, D121Y, K122E, I135V, I142V, K166R, K173A, D177E, T200A, Q207K  
IN.HNR.RT2-5 IN.HNR.RT2-5 RTI RTI   V35T, E36A, T39D, S48T, V60I, K122E, I135T, K173A, D177E, T200A, Q207E, R211K  
IN.HNR.RT2-6 IN.HNR.RT2-6 RTI RTI   V35T, T39D, S48T, V60I, D121H, K122E, I135T, K173E, Q174R, D177E, I178V, T200A, I202V, Q207G, R211K  
IN.HNR.RT2-7 IN.HNR.RT2-7 RTI RTI D67G, K70R, M184V, T215S, K219Q A98G, K101E, Y181C, G190A A33G, V35T, T39E, S48T, V60I, S68G, W88C, V118I, D121Y, K122E, I135T, S162H, T165L, K166R, K173A, D177E, T200A, Q207E, R211K, F214L  
IN.HNR.RT2-8 IN.HNR.RT2-8 RTI RTI   V35T, T39E, S48T, S105A, K122E, D123S, I135R, K173A, D177E, T200A, Q207A, R211K H221N 
IN.HNR.RT2-9 IN.HNR.RT2-9 RTI RTI   V35T, E36A, T39D, S48T, V60I, D121Y, K122E, I135T, K173A, Q174R, D177E, I178L, G196E, T200A, Q207R, R211N, F214L  
IN.HNRT-1 IN.HNRT-1 None None   V35T, T39D, V60I, D121H, K122E, I135R, K173T, T200A, I202V, Q207E, R211K  
IN.HNRT-10 IN.HNRT-10 None None   V35T, T39E, S48T, V60I, K122E, K173A, Q174K, D177E, T200A, I202V, Q207A, R211K  
IN.HNRT-11 IN.HNRT-11 None None   V35T, T39Q, V60I, K122E, I135T, I142V, K173L, Q174K, D177E, Q197K, T200E, Q207A, R211N  
IN.HNRT-12 IN.HNRT-12 None None   V35T, E36A, T39E, S48T, V60I, D121Y, K122E, D123E, I135T, S162G, K173A, D177E, T200A, Q207E, R211K  
IN.HNRT-13 IN.HNRT-13 None None   V35T, E40D, K49R, V60I, K122E, D123S, I135T, S162A, K173L, Q174K, D177E, V179I, G196K, Q197E, T200A, Q207A, R211K, W212L  
IN.HNRT-14 IN.HNRT-14 None None   V35T, E36A, T39E, S48T, V60I, D121Y, K122E, D123E, I135T, S162A, K173A, D177E, T200A, Q207E  
IN.HNRT-15 IN.HNRT-15 None None M41L, D67N, K70R, M184V L100I, K103N V35T, E36A, T39D, V60I, T69N, D121Y, K122E, D123E, K173A, D177E, T200A, Q207E, R211K  
IN.HNRT-16 IN.HNRT-16 None None   V35T, E36A, T39D, V60I, D121Y, K122E, K173T, D177E, T200A, E204K, Q207E, F214L  
IN.HNRT-17 IN.HNRT-17 None None   V35T, T39D, S48T, V60I, K122E, K173T, D177E, T200A, Q207E  
IN.HNRT-18 IN.HNRT-18 None None   V35T, V60I, K122E, I135T, I142V, K173L, Q174K, D177E, Q197K, T200E, Q207D, R211N T39H 
IN.HNRT-19 IN.HNRT-19 None None   V35T, T39Q, V60I, K122E, I135T, I142V, K173L, Q174K, D177E, Q197K, T200E, Q207D, R211N  
IN.HNRT-2 IN.HNRT-2 None None   V35T, T39D, V60I, D121H, K122E, I135R, K173T, T200A, I202V, Q207E, R211K  
IN.HNRT-20 IN.HNRT-20 None None   V35T, E36A, T39E, S48T, V60I, D121H, K122E, I135T, K166R, K173T, Q174R, D177E, T200A, Q207A, R211K  
IN.HNRT-21 IN.HNRT-21 None None   V35T, E36A, T39E, V60I, D121H, K122E, I135T, K166R, K173T, Q174R, D177E, T200A, Q207A, R211K  
IN.HNRT-22 IN.HNRT-22 None None   L34F, V35T, E36A, T39E, S48T, V60I, D121H, K122E, I135T, K173A, D177E, I178L, T200A, Q207E  
IN.HNRT-23 IN.HNRT-23 None None   V35T, E36A, T39D, S48T, V60I, K122E, I135T, K166R, K173A, Q174R, D177E, T200A, Q207E, R211K  
IN.HNRT-24 IN.HNRT-24 None None   V35K, E36A, T39D, S48T, V60I, D121Y, K122E, T139A, T165I, K173E, D177E, T200A, Q207E, R211K  
IN.HNRT-25 IN.HNRT-25 None None M41L, D67N, T69D, K70R, M184V L100I V35T, E36A, T39D, V60I, D121Y, K122E, D123E, K173A, D177E, T200A, Q207E, R211K  
IN.HNRT-26 IN.HNRT-26 None None   V35T, T39D, S48T, V60I, D121H, K122E, K173A, D177E, I178L, T200A, Q207D, R211K  
IN.HNRT-27 IN.HNRT-27 None None   V35T, E36A, T39E, S48T, V60I, D121Y, K122E, I135T, S162A, K173A, D177E, Q197K, T200A, Q207G, R211K  
IN.HNRT-28 IN.HNRT-28 None None   V35T, E36A, T39D, S48T, V60I, D121Y, K122E, I135T, T165I, K173T, D177E, I178L, T200A, Q207K, R211K  
IN.HNRT-29 IN.HNRT-29 None None   V35T, E36A, T39D, S48T, V60I, K102R, D121Y, K122E, I135T, T165I, K173A, Q174R, D177E, I178L, T200A, Q207D, R211K  
IN.HNRT-3 IN.HNRT-3 None None   V35T, T39D, V60I, D121Y, K122E, I135R, S162A, K173A, D177E, T200A, Q207E, R211K  
IN.HNRT-30 IN.HNRT-30 None None   V35T, E36A, T39D, S48T, V60I, W88S, K101R, D121Y, K122E, I135V, S162H, K166R, K173T, D177E, T200A, Q207E V118F 
IN.HNRT-31 IN.HNRT-31 None None  V106M V35T, E36A, T39D, S48T, V60I, D121Y, K122E, I135T, S162A, K173A, D177E, T200A, Q207N, R211K  
IN.HNRT-32 IN.HNRT-32 None None   V35T, E36Q, T39D, K49R, V60I, D123E, I135T, S162A, K173T, D177E, T200A, I202V, Q207G, R211K  
IN.HNRT-33 IN.HNRT-33 None None   V35T, T39E, S48T, V60I, K103R, D121Y, K122E, I135V, K173A, Q174K, E194A, T200A, I202V, Q207A, R211K  
IN.HNRT-34 IN.HNRT-34 None None   V35T, T39E, S48T, V60I, K122E, K173A, Q174K, D177E, T200A, I202V, Q207A, R211K  
IN.HNRT-35 IN.HNRT-35 None None   V35T, T39E, V60I, K64R, D121Y, K122E, I135R, K166R, K173A, Q174R, N175H, D177E, T200A, K201I, Q207E, R211K  
IN.HNRT-4 IN.HNRT-4 None None   V35T, T39E, S48T, V60I, D121Y, K122E, D123E, I135R, S162A, K166R, K173T, D177E, T200A, Q207E, R211K  
IN.HNRT-5 IN.HNRT-5 None None   V35T, E36A, T39D, V60I, K122E, D123S, K173A, D177E, I178M, T200A, Q207E, R211K  
IN.HNRT-6 IN.HNRT-6 None None   V35T, T39D, S48T, V60I, D121Y, K122E, I135T, S162A, K173A, T200A, Q207G, R211K  
IN.HNRT-7 IN.HNRT-7 None None   V35T, E36A, T39E, V60I, D121H, K122E, I135T, K166R, K173T, Q174R, D177E, T200A, Q207G, R211K  
IN.HNRT-8 IN.HNRT-8 None None D67N, T69D, F116Y, Q151M, M184V K101P, K103N K32E, V35T, E36A, T39E, S48T, E53D, V60I, K104R, D121H, K122E, I135T, S162F, K173I, Q174K, V179I, T200A, Q207E, F214L  
IN.HNRT-9 IN.HNRT-9 None None   V35K, T39D, S48T, E53D, V60I, D121Y, K122E, S162A, K173T, Q174K, D177E, T200A, Q207E  
INHRRT1-1 INHRRT1-1 RTI RTI   V35T, T39E, S48T, V60I, K102Q, K104R, D121H, K122E, K173A, T200A, Q207V, R211K  
INHRRT1-10 INHRRT1-10 RTI RTI   V35T, E36A, T39D, S48T, V60I, D121Y, K122E, S162A, E169K, K173T, D177E, T200A, Q207E, R211K  
INHRRT1-11 INHRRT1-11 RTI RTI   V35T, E36A, T39E, S48T, V60I, K122E, D123S, K173A, Q174K, D177E, T200A, Q207A, R211K  
INHRRT1-12 INHRRT1-12 RTI RTI D67N, T69D, K70R, V75M, M184V K103N, E138Q V35T, E36A, T39D, V60I, K101A, D121Y, K122E, I135K, S162C, K173A, D177E, I178L, T200A, Q207E, R211K  
INHRRT1-13 INHRRT1-13 RTI RTI   V35T, E36A, T39E, S48T, V60I, D121Y, K122E, I135R, K166R, K173I, D177E, T200A, Q207T, R211K  
INHRRT1-14 INHRRT1-14 RTI RTI M184I  V35T, E36A, T39D, M41I, G45R, S48T, G51R, E53D, V60I, G93R, G112E, D121Y, K122E, G141E, R143K, K166R, R172K, K173A, D177E, G190R, G196R, T200A, Q207E, R211K G152R 
INHRRT1-15 INHRRT1-15 RTI RTI   V35T, E36A, T39D, E40D, S48T, V60I, D121Y, K122E, K166R, K173A, D177E, G196E, Q207E  
INHRRT1-16 INHRRT1-16 RTI RTI   V35T, E36A, T39E, E40D, K43R, S48T, V60I, D121Y, K122E, I135T, K173E, Q174R, D177E, T200A, Q207E, R211K, F214L  
INHRRT1-17 INHRRT1-17 RTI RTI   V35T, E36A, T39E, E40D, K43R, S48T, V60I, D121Y, K122E, I135T, K173E, Q174R, D177E, T200A, Q207E, R211K, F214L  
INHRRT1-18 INHRRT1-18 RTI RTI   V35T, E36A, T39E, S48T, V60I, A98S, D121Y, K122E, K166R, K173A, Q174R, D177E, I178M, T200A, Q207D, R211K  
INHRRT1-19 INHRRT1-19 RTI RTI  E138A V35T, T39E, S48T, V60I, D121H, K122E, I135L, I142T, K173T, Q174R, D177E, I178L, T200A, Q207N, R211K Y115D 
INHRRT1-2 INHRRT1-2 RTI RTI   V35T, T39E, S48T, V60I, K101Q, D121Y, K122E, I135K, S162C, K173V, Q174K, D177E, T200A, Q207N, R211Q  
INHRRT1-20 INHRRT1-20 RTI RTI   V35T, T39E, S48T, D121H, K122E, T165I, K173T, D177E, I178L, V179I, T200A, Q207E, R211K  
INHRRT1-21 INHRRT1-21 RTI RTI   V35T, T39E, V60I, D121Y, K122E, I135R, K173A, D177E, I178L, T200A, Q207K, R211K  
INHRRT1-22 INHRRT1-22 RTI RTI   K32E, V35T, E36A, T39N, S48T, V60I, D121Y, K122E, I135R, S162A, K173A, D177E, T200A, Q207E  
INHRRT1-23 INHRRT1-23 RTI RTI   V35T, E36A, T39D, V60I, D121Y, K122E, K173A, D177E, T200A, Q207E, R211K  
INHRRT1-24 INHRRT1-24 RTI RTI  E138A V35T, E36A, T39D, S48T, V60I, W88S, D121Y, K122E, S162H, K166R, K173A, D177E, T200A, Q207E, F214L  
INHRRT1-25 INHRRT1-25 RTI RTI  K103N V35T, T39E, S48T, V60I, D121Y, K122E, I135T, S162A, K173A, D177E, T200A, Q207G, R211K K101G 
INHRRT1-26 INHRRT1-26 RTI RTI   V35T, E36A, T39D, S48T, V60I, D121Y, K122E, K166R, K173A, D177E, T200A, Q207A, R211K  
INHRRT1-27 INHRRT1-27 RTI RTI M184V K103N V35T, E36A, T39D, S48T, V60I, D121Y, K122E, T139R, K173A, T200A, Q207E, R211K  
INHRRT1-28 INHRRT1-28 RTI RTI D67N, K70R, M184V K103N V35T, E36A, T39D, V60I, D121Y, K122E, I135T, S162A, D177G, T200A, Q207E  
INHRRT1-29 INHRRT1-29 RTI RTI   V35T, E36A, T39D, S48T, V60I, V90I, S105A, D121Y, K122E, S162A, K173A, Q174K, D177E, G196K, T200A, Q207K, R211E  
INHRRT1-3 INHRRT1-3 RTI RTI   V35T, E36A, T39D, S48T, V60I, D121Y, K122E, S162A, K173A, D177E, T200A, Q207E, R211K  
INHRRT1-30 INHRRT1-30 RTI RTI   V35T, E36A, T39N, E40D, S48T, V60I, K173A, D177E, T200A, Q207N, R211K  
INHRRT1-31 INHRRT1-31 RTI RTI   V35T, T39E, S48T, V60I, D121Y, K122E, D123G, K173A, D177E, V189I, T200A, Q207G, R211K  
INHRRT1-32 INHRRT1-32 RTI RTI   V35T, T39E, S48T, V60I, I135R, K173A, D177E, T200A, Q207E, R211K  
INHRRT1-33 INHRRT1-33 RTI RTI M41L, D67N, V75M, F77L, M184V, T215N K101E, V106M, G190A V35T, T39D, E44D, S48T, V60I, D121Y, K122E, I135R, S162A, K173A, D177E, T200A, Q207K, R211Q  
INHRRT1-34 INHRRT1-34 RTI RTI   V35K, T39D, S48T, V60I, K104R, D121Y, K122E, S162A, T165I, K173A, Q174K, D177E, Q207E, R211K  
INHRRT1-35 INHRRT1-35 RTI RTI   V35K, E36A, T39D, S48T, V60I, K122E, D123G, K173A, D177E, T200A, Q207E  
INHRRT1-36 INHRRT1-36 RTI RTI   V35T, E36A, T39D, E40K, S48T, V60I, K103R, D121H, K122E, K173A, Q174K, T200A, Q207E, R211K  
INHRRT1-37 INHRRT1-37 RTI RTI   V35I, E36A, T39E, V60I, D121H, K122E, I135T, I142T, K173A, Q174R, D177E, I178L, T200A, Q207E, R211K, F214L  
INHRRT1-38 INHRRT1-38 RTI RTI   V35T, T39D, S48T, V60I, T69I, D123E, I135V, S162A, K173T, D177E, T200A, Q207G, R211K  
INHRRT1-4 INHRRT1-4 RTI RTI   V35T, E36A, T39E, S48T, V60I, K122E, D123S, I135T, T165I, D177E, T200A, Q207E, R211K  
INHRRT1-5 INHRRT1-5 RTI RTI   K32Q, V35T, E36A, T39D, S48T, V60I, D121Y, K122E, I135R, S162A, K173T, D177E, I178L, T200A, Q207E  
INHRRT1-6 INHRRT1-6 RTI RTI   V35T, E36A, T39D, S48T, V60I, D121H, K122E, I135R, S162A, K173T, D177E, I178L, T200A, Q207E  
INHRRT1-7 INHRRT1-7 RTI RTI   V35T, E36A, T39E, S48T, E53D, V60I, D121Y, K122E, I135T, S162A, K173T, Q174K, D177E, Q197K, T200A, Q207E  
INHRRT1-8 INHRRT1-8 RTI RTI   V35T, E36A, T39D, S48T, V60I, D121H, K122E, I135T, S162C, K173A, D177E, T200A, Q207A, R211K  
INHRRT1-9 INHRRT1-9 RTI RTI   V35T, E36A, T39D, S48T, V60I, K122E, D123S, I135R, K173A, T200A, Q207E, R211K