Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Alaoui (2018)
Title Prevalence of resistance to integrase strand-transfer inhibitors (INSTIs) among untreated HIV-1 infected patients in Morocco.
Citation BMC Res Notes
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 77
NumPts 77
Subtype B, CRF02_AG, A, C, G, CRF08_BC

 

Clinical IN Isolates


SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
1079/13 1079/13 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
11059/14 11059/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
11064/14 11064/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
11093/14 11093/14 None   T97A L101I, T112V, T124A, T125A, G134E, I135V, K136T, D167E, V201I, L234I  
11281/14 11281/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
11327/14 11327/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
11444/13 11444/13 None    E11D, A21T, V31I, S39C, L45Q, M50I, L101I, S119P, T122I, I203M, N254K  
11901/14 11901/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
11902/14 11902/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
11910/10 11910/10 None    K14R, V32I, S39C, L101I, K111A, I113V, S119P, T122I, T124N, T125A, V201I, A205S, T206S, K240R, D256E  
11989/14 11989/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
12008/14 12008/14 None    E11D, S39C, M50I, S119P, V165I, T218S, D253E, D256E, S283G  
12354/14 12354/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
12563/10 12563/10 None    E11D, S39C, L101I, K103R, K111T, S119P, T122I, T124A, Y227F, D256E  
13004/12 13004/12 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
13287/14 13287/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
13289/14 13289/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
13333/14 13333/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
13430/14 13430/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
13752/11 13752/11 None    A91T, L101I, K111S, S119R, S123C, T124N, T218I, Q221S, L234I, D256E  
14040/14 14040/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
14153/13 14153/13 None    K14R, L28I, V31I, M50L, L101I, K111T, T112V, T125A, G134N, I135V, K136T, I203M, L234I  
14184/14 14184/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
14345/11 14345/11 None    E11D, L28I, K156N, E198D, V201I, T206S, T218S, D270N  
1557/14 1557/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
15860/12 15860/12 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, D256E, D286N  
15866/14 15866/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
16451/11 16451/11 None    K14R, A21S, V31I, S39C, L101I, K103R, K111T, S119P, T122I, T124A, R187K, T206S, Y227F, D256E  
16707/14 16707/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
17088/13 17088/13 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
17152/14 17152/14 None    K14R, R20K, S24N, V31I, I72V, I84M, L101I, T112V, T124A, T125A, G134N, K136T, V201I, T206S, L234I, S283G E87G 
17186/14 17186/14 None    E11D, R20K, I72V, L74M, T112V, I113V, S119P, T122I, T124N, T125A, V126M, S230N, S255G, D256E, S283G  
17423/14 17423/14 None    K14R, R20K, S24N, V31I, I72V, I84M, L101I, T112V, T124A, T125A, G134N, K136T, V201I, T206S, L234I, S283G  
17429/14 17429/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
17430/14 17430/14 None    E11D, A21T, A98G, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, I203M, L234I  
17465/13 17465/13 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
17486/14 17486/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, Q221H, S230N, N254S, S255G, D256E, D286N  
17499/14 17499/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
17643/13 17643/13 None    E11D, R20K, S24G, D25E, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
18071/13 18071/13 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
18428/14 18428/14 None    E11D, R20K, S24G, L45Q, I60M, K71Q, S119T, T122I, T124N, T125A, G193E, Q221H, S255G, D256E, D286N  
18860/12 18860/12 None    K14R, L28I, V31M, V32I, S39H, M50T, I84M, L101I, T112V, S119P, T124N, I135V, K136Q, V201I, T206S, D207E, K211R, T218I, L234I, N254Q, S255G, R269K, D278A  
18942/11 18942/11 None    S17N, V31I, S39C, M50I, L101I, K103R, K111T, S119P, T122I, T124A, G163T, K173R, Y227F, D256E  
1927/15 1927/15 None    E11D, S17T, V37I, L45I, I72V, S119P, T122V, T124A, T125A, G163Q, L234I, S255G  
19357/10 19357/10 None    E11D, S57G, T112V, T124A, T125A, G134N, I135V, K136T, L234I  
20307/13 20307/13 None    E11D, S24G, D25E, S39C, L45V, L101I, T112I, S119P, T124N, T125A, I135V, D167E, V201I, T206S  
20622/13 20622/13 None    K14R, S24N, L28I, V31I, M50L, L101I, K111T, T112V, T125A, G134N, I135V, K136T, I203M, I208L, K211R, L234I  
20633/13 20633/13 None    K14R, L28I, V31I, V32I, M50L, L101I, T112V, T125A, G134N, I135V, K136T, I203M, I208L, L234I  
2368/11 2368/11 None    E11D, R20K, A21T, V31I, I72V, L74I, T112V, S119P, T124A, T125A, V126M, G134N, K136Q, D167E, V201I, T218S, Y227F, L234I, N254K, S255G  
3241/14 3241/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, D256E  
3262/14 3262/14 None    E11D, A21T, A98G, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, I203M, L234I, S283G  
3311/12 3311/12 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
3658/11 3658/11 None    E11D, K14R, S24N, V31I, L101I, T112V, T124N, T125A, G134N, I135V, K136T, G163E, V201I, L234I, S283G  
3676/11 3676/11 None    V31I, M50I, I72V, L101I, S119P, T122I, T125A, G163E, V201I, D279G  
3973/14 3973/14 None    E11D, A21T, S39C, L45Q, M50I, L101I, S119P, T122I, T125A, V126A, N254K  
4245/13 4245/13 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
4429/15 4429/15 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
4495/13 4495/13 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
4630/13 4630/13 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
5668/14 5668/14 None    E11D, S24G, D25E, L45Q, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, S255G, D256E, D286N  
5941/12 5941/12 None    E11D, V31I, V32I, K71R, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, D167E, V201I, I203M, L234I  
6013/14 6013/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
6440/15 6440/15 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
6600/14 6600/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
6797/12 6797/12 None    V31I, V37I, M50T, V77I, I84M, L101I, T112V, T124N, T125A, K136Q, T206S, T218I, L234I, N254Q, S255G, D278A, S283G  
6970/11 6970/11 None    V31I, V32I, L101I, T112V, T125A, G134N, I135V, K136T, V201I, I203M, K219T, N222K, L234I  
7005/15 7005/15 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
8037/12 8037/12 None    S17N, L28I, E35Q, D41N, M50I, L74I, G163E, K211Q, D256E  
8091/12 8091/12 None    E11D, A23V, V31I, A38T, L45Q, I72T, L101I, T112V, T125A, K127R, G134N, I135V, K136T, D167E, V201I, L234I  
8734/14 8734/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
9412/11 9412/11 None    E10D, E11D, K14R, A21T, V31I, S39C, M50I, I72V, S119P, T124N, V165I, D256E  
9739/13 9739/13 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
985/13 985/13 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
9873/14 9873/14 None    L101I, S119T, T206S, K211Q, S230N, D256E, I268L, D270N  
9874/14 9874/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
9875/14 9875/14 None    V31I, S57N, L101I, T112V, T124N, G134K, K136T, V201I, T206S, L234I, D256E  
9957/12 9957/12 None    E10D, V31I, V32I, M50L, A91T, L101I, K111T, S119T, T124N, T125A, I135V, V165I, V201I, Y227F, S230N, R231K, D253H