Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Jeong (2018)
Title Integrase Strand Transfer Inhibitor Resistance Mutations in Antiretroviral Therapy-Naive and Treatment-Experienced HIV Patients in South Korea.
Citation ARHR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 94
NumPts 94
Subtype B, CRF01_AE, CRF44_BF, CRF07_BC, CRF06_cpx

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
AKH 472 AKH 472 Unknown Unknown  V179D E6D, K11T, V35T, T39K, K43E, V118I, D121A, K122E, D123S, I135T, K173R, Q174E, D177E, T200R, Q207A, R211S, F214L, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D  
AYH 509 AYH 509 Unknown Unknown   V35I, D123E, I135L, G196E, T200I, A272P, T286A, A288G, I293V, E297A, R307RG, I326V  
BDS 528 BDS 528 Unknown Unknown   D177E, Q207E, V245E, I293V, E312A, I329V  
CDJ 434 CDJ 434 Unknown Unknown   V35I, K104R, K122E, I135IT, G196E, T200I, K201R, E204K, Q207E, F214L, K281R, I293V, E328D, Q334I  
CIK 489 CIK 489 Unknown Unknown   K122E, D123S, I178M  
CIK 503 CIK 503 Unknown Unknown   E6D, V60I, K122E, I135T, T200TI, I202V, Q207QH, R211K, V245K, A272P, I293V, Q334E  
CMH 535 CMH 535 Unknown Unknown  V179E V35I, D121Y, K122E, I135T, D177E, G196E, T200A, E204K, Q207E, F214L, V245M, I293V, E298A, E312Q, D324E, I329L  
DSN 522 DSN 522 Unknown Unknown   V21I, E28K, K32E, V35T, E36A, T39E, S48T, E53D, V60I, D121Y, K122E, I135T, V245Q, E248V, K249Q  
HKB 491 HKB 491 Unknown Unknown   R83K, T200A, R211G, V245Q, G262GE, A272P, V276I, E297T  
HSC 483 HSC 483 Unknown Unknown   S48SL, P52PA, K82KR, K103KR, S163N, E169D, F171FL, G196E, Q207E, R211RK, V245E, I293V T84TA, Q85QE, L92LF, R143RI 
HSI 435 HSI 435 Unknown Unknown   E6D, V118I, K122E, K173N, Q174K, T200TK, R211Q, F214L, V245Q, I293V, E297K, E312D, E328D, Q334L W229W* 
HSI 486 HSI 486 Unknown Unknown   K122E, I135R, Q207E, V245M, I293V, E312V, I329V, G333D  
HSI 537 HSI 537 Unknown Unknown K70G, M184V  E6D, V118I, K122E, K173N, Q174K, V179VI, T200K, R211Q, F214L, V245Q, I293V, E297K, E328D, Q334L  
HSJ 532 HSJ 532 Unknown Unknown   V60I, I135V, T139I, K173E, G196E, T200I, E204K, Q207E, F214L, V245Q, S251C, T286A, I293V, P313Q, Q334E  
HSK 443 HSK 443 Unknown Unknown   K20R, K122KE, K173N, Q174QK, I178IL, T200I, Q207R, V245K, V292VI, I293IV, V317IM, Q334L  
HSP 479 HSP 479 Unknown Unknown   E6D, K11T, V35T, T39TNS, E40ED, V60I, D121Y, K122E, I142V, K173I, Q174K, D177E, I178M, T200X, Q207A, R211S, V245E, K249R, S251N, A272P, T286A, V292VI, I293V, E297K, A304E, E312NT, I326V, I329V, G335D  
JDH 481 JDH 481 Unknown Unknown   K122E, I135T, I178V, V245M, I293V, P313Q  
JDRY 473 JDRY 473 Unknown Unknown  P225PH A98S, D121H, K122E, I135T, N175H, P176PQ, Q197E, T200KR, I202V, E204D, R211KT, I293V, D324E, I329L  
JHW 484 JHW 484 Unknown Unknown M184V  V35I, K122E, I135T, I202V, R211K, V245Q W153W* 
JHY 461 JHY 461 Unknown Unknown   V35I, K101KR, K122E, I135T, D177DN, T200TI, I202V, R211K, V245Q, E312H, I326IT, I329L, G335GD I47IV 
JHY 485 JHY 485 Unknown Unknown   V35I, S68G, E79EK, K122E, I135R, I178L, V179VI, G196E, T200Q, Q207E, D250DN, S251C, A272S, A288S, I293V, P313Q, Q334L E204I 
JJB 430 JJB 430 Unknown Unknown  V179E K20R, K102KR, K122E, D123N, G196E, T200K, Q207E, V245K, K249Q, A288S, I293V, P313Q, V317A, Q330QR, Q334R  
JJS 427 JJS 427 Unknown Unknown   E28K, K32E, V35T, E36A, T39D, S48T, V60I, D121HY, K122E, V245Q, K249Q, A272P, K277R, T286A, E291D, V292I, I293V, V317A, G335D  
JJY 449 JJY 449 Unknown Unknown   E6D, V35I, T39AS, S68G, K122E, I135T, L187I, V189A, G196E, T200R, Q207E, R211K, F214L, V245Q, I293V  
JKY 460 JKY 460 Unknown Unknown   V35VI, V60I, K122E, D123S, R125RG, I135R, Q174E, I202V, Q207H, R211K, V245K, I293V, E312H, I329L  
KBS 456 KBS 456 Unknown Unknown  E138G, V179D K20R, V35T, V60I, K104R, I135V, G196E, T200I, E203D, Q207E, F214L, V245Q, S251C, I293V, K311KR, P313Q, V317VA, Q334X, G335GD  
KBS 478 KBS 478 Unknown Unknown   E6D, V8I, K11T, V21I, V35T, T39K, K43E, K49R, V60I, K122E, D123S, I135IT, R172RK, K173I, Q174K, D177E, I178M, T200A, E204Q, Q207A, R211S, K238R, V245E, E291D, V292I, I293V, E312T, I326V, I329V, G335D K82KT 
KCH 474 KCH 474 Unknown Unknown  V179VD K103X, V118I, K122E, G196E, T200I, E204K, Q207E, R211RK, F214L, A272P, I293V, V317A, D324DE, G333D  
KDH 440 KDH 440 Unknown Unknown M184V, K219KE K103KN E6ED, W88C, K101KQ, K173N, G196GE, T200I, R211K, D237N, V245K, A272P, V276I, I293V, E328D T216TK 
KDH 466 KDH 466 Unknown Unknown   T7TS, V118I, D121DH, K122X, I135T, T139A, I142IKN, G196E, T200I, E204K, Q207E, F214L, A288S, E297R, I326V  
KDS 471 KDS 471 Unknown Unknown M41L, Y115YF, M184V V179E E28KR, K32E, V35K, T39A, V60I, D123E, T139A, G141GR, R143RK, Q174R, D177E, T200A, Q207E, R211K, V245Q, E248D, D250E, T286A, V292I, I293V, E297A, S322L, I329V, G335D Y146N 
KDY 492 KDY 492 Unknown Unknown   V35M, K103R, K104R, I135V, I142V, S162SN, P176PS, G196E, T200I, Q207E, F214L, V245Q, S251C, A272S, I293V, P313Q, Q334L  
KEK 476 KEK 476 Unknown Unknown  K103N T7P, V118I, K122KE, D123N, Y127YF, I135T, S163C, Q174H, G196E, T200I, Q207E, F214L, V245K, I293V, K311R, D324E, Q334L N175NK 
KES 523 KES 523 Unknown Unknown M41L, M184V, L210W, T215F K103S E6D, K122E, Q174E, T200TA, Q207E, V245K  
KHH 467 KHH 467 Unknown Unknown K65KR, K70KE, M184V  E6K, E28EA, K32KE, S68SN, V118I, K122E, I135T, N175H, G196E, T200K, K201R, R211S, F214L, T290TA, I293V, I326V  
KHJ 482 KHJ 482 Unknown Unknown   K102R, D121H, K122E, I135T, K173E, Q174QK, T200I, Q207E, R211K, A272T, I293V  
KHM 515 KHM 515 Unknown Unknown   V35T, E44K, V60I, K104R, I135T, I142V, R211A, V245K, T286A, I293V, P313Q, G333E L283LP 
KIH 448 KIH 448 Unknown Unknown   V8I, D123E, I135V, D177E, T200E, I202V, R211K, V245N, Q278H, L283I, I293V, K311Q, E312T, I329L  
KJB 450 KJB 450 Unknown Unknown K65KR, M184V V106I, V179D, G190A E6K, V35I, S68SN, K103R, K122E, I135L, T200K, F214L, K277R, A288AT, I293V, E297R, E312T, Q334L  
KJH 439 KJH 439 Unknown Unknown   E6D, K122E, I178L, R211A, K238KR, V245K, I293V, K311KN, P313PQ  
KJH 445 KJH 445 Unknown Unknown   K122E, I135T, G196E, T200TI, K201R, E204K, R211T, F214L, I293V  
KJH 447 KJH 447 Unknown Unknown M184V L100LI, V106VI, E138A, V179VIL, H221HY, F227FC K20R, K102R, D121H, K122E, I135T, T139I, S162C, I178L, T200TI, K219X, V245E, I293V  
KJH 533 KJH 533 Unknown Unknown  K103N K20R, V35E, T39A, V90I, K122E, D123E, I135R, V179I, T200E  
KJK 477 KJK 477 Unknown Unknown K70EQ, Y115F, M184V V179D V35I, D123E, I135T, T200V, Q207K, R211A, K223R, V245E, A272S, T286A, I293V, P313K, S322T, I329L, Q334H, G335D Y183YC 
KJS 470 KJS 470 Unknown Unknown   E6D, V8VI, E53EG, I202V, R211K, V245K, I293V, I329LV  
KJW 488 KJW 488 Unknown Unknown   V118I, K122E, I135T, T139A, I178IM, G196E, T200R, E204K, Q207K, R211I, F214L, V245I  
KJY 462 KJY 462 Unknown Unknown   E6K, K122E, I135V, I178M, L187I, G196E, T200I, E204K, Q207E, F214L, V245Q, S251C, T286A, I293V, K311KR, P313Q, I329IV, Q334E  
KMH 465 KMH 465 Unknown Unknown   K32Q, V35K, V118I, D121H, K122E, D123DN, T139TA, I142IT, D177E, I178IM, G196E, Q207E, F214L, I244IV, V245ILM, I293V, D324E, I329V, Q334L  
KMH 521 KMH 521 Unknown Unknown   E6D, K11T, K32R, V35T, T39K, K43E, K122E, D123N, S162C, K173R, Q174K, D177E, I178M, V179I, Q207A, R211S, K238R, V245E  
KSB 508 KSB 508 Unknown Unknown   E6D, V8I, K11T, V21I, V35T, T39R, K43E, K49R, V60I, K122E, D123S, I135M, K173I, Q174K, D177E, I178M, V179I, T200A, E204Q, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, E312T, I326V, I329V, G335D  
KTW 452 KTW 452 Unknown Unknown M184V E138K E6D, V35I, V90VI, K122E, I135T, I178M, T200I, R211A, V245I, L283LI, I293V, P313Q  
KYH 494 KYH 494 Unknown Unknown M184V  E6D, D121H, I135M, I178M, T200K, I202V, Q207E, L283I, T286P, I293V, E312T  
KYI 517 KYI 517 Unknown Unknown   K20R, K122E, I135V, S162N, V179A, G196E, I202V, R211A, F214L, V245Q, S251C  
LBN 527 LBN 527 Unknown Unknown   E6D, D123E, D177E, I178M, T200I  
LCW 436 LCW 436 Unknown Unknown M184MV  V118VI, D121DH, K122AE, I135IT, Q174K, T200TA, R211RKQ, F214FL  
LDK 505 LDK 505 Unknown Unknown   E6D, I135T, S162C, R211K, E248V, I293V, S322T  
LHC 469 LHC 469 Unknown Unknown   K20R, Q174H, T200R, Q207E, R211K, A272S, I293V, K311R, V317A, G333E  
LHD 500 LHD 500 Unknown Unknown   A98S, K102Q, K103R, D123E, T200M, I202V, R211K I37IT 
LJH 428 LJH 428 Unknown Unknown  V179D P4X, E6ED, A98S, K102KQR, K122E, E169D, T200V, I202IV, A288S, I293V, K311R  
LJH 520 LJH 520 Unknown Unknown   K49R, R83K, K122E, T200I, R211G, V245K, A272P, V276I, E297T, P313T, I329T, Q334H  
LJI 458 LJI 458 Unknown Unknown  V179E K20R, V35I, K122E, E169D, E194X, G196E, I202V, R211S  
LJK 487 LJK 487 Unknown Unknown  K101P, K103NS V90VI, D121H, K122E, I135R, T200I, W212X, V245T, L246I, V276I, I293V, E312Q, S322T, Q334QE Y183YD, L187LV 
LJW 499 LJW 499 Unknown Unknown   K122KE, D123X, I135X, K173N, E194Q, G196E, T200A, Q207H, R211K, V245VM  
LKI 475 LKI 475 Unknown Unknown  V179VD V35VI, T39TA, K122E, I135T, Q174R, G196E, T200A, I202V, Q207E, F214L, V245VI, A288S, I293V, K311KR, I326V, Q334L  
LST 495 LST 495 Unknown Unknown  K103N V35M, D121HY, K122E, D192DN, T200I, R211S, V245I, I293V, E297EK, Y319F  
LTH 437 LTH 437 Unknown Unknown   V35I, D123E, I135T, D177E, R211K, F214L, A272P, T286P, V292I, I293V, E297R, L301I, E328D  
LYS 502 LYS 502 Unknown Unknown   V118I, K122KE, T139A, T165I, Q174H, G196E, T200I, Q207E, F214L, G262GR, V292I, I293V, K311R T84TN, D256A 
OSJ 530 OSJ 530 Unknown Unknown  V106I V118I, K122E, I135T, T139A, Q174H, G196E, Q207E, F214L, V245K, I293V, D324E, Q334L  
PHB 504 PHB 504 Unknown Unknown  V108VI E6D, E36EK, V60I, I142V, S162X, T165TI, T200S, E204EQ, Q207X, R211K, V245E, K249R, A272ST, I293V, E312T, I329IV, Q334DE, G335NS  
PHK 511 PHK 511 Unknown Unknown M184I Y181C V35L, V118I, K122E, T139A, K166R, G196E, Q197K, T200I, Q207E, F214L, A272P, I293V, H315HQ, Q332QR, G333D  
PHS 506 PHS 506 Unknown Unknown   V35I, K102R, V118I, D123E, K173R, T200I, E203D, Q207E, R211K, F214L, V245E, I293V, E298EK, I329L  
PJS 493 PJS 493 Unknown Unknown  V108VI, K238KT K20R, V35I, K102R, D121H, K122E, I135T, S162A, E169EK, D177E, I178IL, G196GE, T200E, V245EQ, D250E P25PL 
PJS 531 PJS 531 Unknown Unknown   K20R, K122E, I135V, V179A, G196E, I202V, R211A, F214L  
PJW 525 PJW 525 Unknown Unknown   V35I, K122E, I135T, I178IM, T200I, R211T, V245M  
PKC 441 PKC 441 Unknown Unknown M184I  V90I, K102Q, K122E, I178L, I202V, R211K, F214L, V245E, I293V, E297A, E312Q, I329L  
PKS 431 PKS 431 Unknown Unknown   S68G, V90VI, K122E, D177DE, I178ILM, T200TA, E204EAD, Q207ADE, R211RK, V245VM, I293V  
PKW 524 PKW 524 Unknown Unknown   E6K, K122E, I135V, I178M, L187I, G196E, T200I, E204K, Q207E, F214L, V245Q, S251C  
PSJ 429 PSJ 429 Unknown Unknown M41ML, T215DY V179VD K20KR, K122E, I135T, Q174K, G196E, T200I, Q207H, H208HY, R211K, A272P, I293V, E297A, V317A, G333GE, Q334L  
PSJ 457 PSJ 457 Unknown Unknown   E6D, E28EG, V60I, A98S, D121HY, K122E, D123DE, I135T, F171Y, T200E, Q207E, V245K, K281KR, I293V, K311R, I329L  
PWJ 433 PWJ 433 Unknown Unknown M184V  K122X, D123DE, I135T, K173DN, Q174K, T200A, Q207E, V241VI, A272S, K275Q, I293V, P294V, E312EQ, V317A, I329L, Q334D  
PYG 464 PYG 464 Unknown Unknown   V118I, K122E, I135T, E169EA, D177DE, G196E, T200I, R211K, F214L, D237N, I293V, I329V, Q334L  
SBD 432 SBD 432 Unknown Unknown   V35I, K102KR, S134SC, I135X, S162C, D177N, Q207A, R211K, K249Q, T286A, P294Q, V317A, I329L, Q334QP, G335N  
SBS 446 SBS 446 Unknown Unknown   V35T, T39K, K43E, T69TN, A98S, K122E, E169D, K173L, Q174K, D177E, I178IL, G196E, T200A, I202V, Q207A, R211K, K238R, V245E  
SIK 455 SIK 455 Unknown Unknown M184I K101KE, E138EK P4PS, E6EDG, R172RK, G196E, T200TI, E204D, L210F, R211K, D237N, A272S, E297EK, P313T, S322T, Q334E  
SSC 444 SSC 444 Unknown Unknown  K103N V35I, D123E, I135T, I178IM, V179I, T200I, R211K, F214L, V245I, I293V  
SWKG 454 SWKG 454 Unknown Unknown K70R, M184V, K219E K101E, E138EG, Y181I E6ED, K104R, K122E, I135T, S162SN, K166KR, T200M, I202V, R211K, D237N, V245K, I293V, E312Q, I329L  
SYC 471.5 SYC 471.5 Unknown Unknown   V35I, S68G, K102KR, K104KR, K122E, K166KR, I178L, T200I, Q207E, F214FL, V245T, V276I, I293V, E312Q  
WHJ 468 WHJ 468 Unknown Unknown   E6P, K122E, F171Y, T200I, I202V, R211K, V245KQ, I293V, E312T, V317VA, P321L, E328Q A158G 
YIH 426 YIH 426 Unknown Unknown   K11KR, K49R, I135T, S162C, D177E, G196E, Q197QK, Q207AEG, R211RK, K223KR, K277R, L283I, I293V, Q334R, G335D  
YJK 496 YJK 496 Unknown Unknown  V106I, E138EG, Y188L K11KT, K20R, V35VI, T39TI, D121H, K122E, I135T, D177E, V179VI, T200A, F214L, K238KR, K249KE, I293V, P294S, E297A, K311R, P321PL  
YJO 513 YJO 513 Unknown Unknown  V106VI, V179D V35I, K102Q, K122E, I135K, K173R, I202V, R211K, V245K, G262GE, I293V, E297V, E312Q, D324DE, I329L  
YJW 490 YJW 490 Unknown Unknown   E6ED, V21VI, E28EK, V35T, T39X, K43E, K64R, V118VI, D121DY, K122E, D123GS, I135IT, S162C, K173T, Q174K, D177E, Q207A, R211S, K238R, V245E, D250E, A272P, K275R, K281R, T286A, E291D, V292I, I293V, E312T  
YSH 451 YSH 451 Unknown Unknown   V35VIL, V118VI, V179VI, T200IV, I202V, Q207QKR, R211K, V245E, L283I, I293V, E312H, S322T, I329L  
YYI 507 YYI 507 Unknown Unknown   E6D, K103R, D121H, K122E, R125G, I135IM, K173Q, T200I, K238R, V245I, A272P, I293V, I326M, Q334E Y127YS