Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Saladini (2017)
Title The HIV-1 integrase E157Q polymorphism per se does not alter susceptibility to raltegravir and dolutegravir in vitro.
Citation AIDS
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 6
NumPts 6
Subtype CRF02_AG, B

 

Clinical IN Isolates


SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
P142057 P142057 None   E157Q S57N, L101I, S119G, T122I, T124A, K160Q, F181L, T206S, D253E, D256E  
P147829 P147829 None   E157Q A8D, K14R, R20K, V31I, M50T, S57G, I72IV, T112V, T124A, T125A, G134N, I135V, K136T, K160Q, V201I, T206S, L234I, D256E, S283G, R284RK  
P147847 P147847 RAL   E157Q K14R, P30S, A33AT, L45I, M50MI, I60V, I72V, L101I, T112I, T124A, T125A, G134N, I135V, K136T, K160S, S195SN, V201I, T206S, L234I, S283G, D288N H16HN 
P148505 P148505 None   E157Q E11D, L101I, S119G, T122I, T124A, K160Q, F181L, T206S, D256E  
P148680 P148680 None   E157Q E11ED, L101V, T112V, T124N, T125A, K160Q, D167E, A205T, S230N, L234I, A265V  
P149029 P149029 None   E157Q S17N, V31I, M50I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136T, K160Q, F181L, V201I, T206S, Q216H, N222K, L234I, I268L