Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Hassounah (2017)
Title Antiviral Activity of Bictegravir and Cabotegravir against Integrase Inhibitor-Resistant SIVmac239 and HIV-1.
Citation Antimicrob Agents Chemother
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
SelectedType Lab
NumIsolates 9
Lab Parent Strain NL43


Lab IN Isolates : Susceptibility Data

IsolateINIMajorDRMsINIMinorDRMsMethodDrugFold Res.
E138K_R263K E138K, R263K  PBMC-McGill BIC 3.4 
     PBMC-McGill CAB 2.1 
     PBMC-McGill DTG 2.4 
G118R G118R  PBMC-McGill BIC 4.3 
     PBMC-McGill CAB 8.0 
     PBMC-McGill DTG 6.7 
G140S_Q148H G140S, Q148H  PBMC-McGill BIC 4.8 
     PBMC-McGill CAB 17 
     PBMC-McGill DTG 7.4 
H51Y_R263K R263K H51Y PBMC-McGill BIC 2.2 
      PBMC-McGill CAB 1.8 
      PBMC-McGill DTG 2.0 
M50I   PBMC-McGill BIC 1.4 
    PBMC-McGill CAB 0.9 
    PBMC-McGill DTG 1.0 
M50I_R263K R263K  PBMC-McGill BIC 3.4 
     PBMC-McGill CAB 1.9 
     PBMC-McGill DTG 2.0 
N155H N155H  PBMC-McGill BIC 1.8 
     PBMC-McGill CAB 2.1 
     PBMC-McGill DTG 1.4 
R263K R263K  PBMC-McGill BIC 2.3 
     PBMC-McGill CAB 2.5 
     PBMC-McGill DTG 1.9 
Y143R Y143R  PBMC-McGill BIC 1.2 
     PBMC-McGill CAB 1.7 
     PBMC-McGill DTG 1.2