Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Rodgers (2017)
Title Sensitive next-generation sequencing method reveals deep genetic diversity of HIV-1 in the Democratic Republic of the Congo.
Citation J Virol
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 14
NumPts 14
Subtype CRF45_cpx, H, C, F, J, CRF25_cpx, CRF02_AG, D

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
CG-0059-01 CG-0059-01 None None  V106I V35T, V60I, K122E, S162C, K173A, Q174K, D177E, I178L, Q207E, R211K, V245K, A272P, Q278H, K281R, T286A, E291A, V292I, I293V, Y339F, F346Y, M357T, G359S, K366R, A376S, T377Q, K390R, A400T, K431T, V435A, V467I, S468T, D471E, H483Q, L491S, L517I, S519N, Q520K, Q524E, E529D, V531I, A534S, A554S I329R 
CG-0062-01 CG-0062-01 None None  V106I V35T, V60I, S162Y, K173A, Q174K, D177E, I178L, Q207E, R211K, V245K, A272P, Q278H, K281R, T286A, E291A, V292I, I293V, Q330E, Q334N, Y339F, F346Y, M357T, G359S, K366R, A376S, T377Q, K390R, A400T, K431T, V435A, V467I, S468T, D471E, H483Q, L491S, L517I, S519N, Q520K, Q524E, E529D, V531I, A534S, A554S I329A, K331D, Q332S, L368R 
CG-0066-01 CG-0066-01 None None   V35T, K49R, V60I, V90I, A158S, K173T, Q174K, D177E, G196E, Q207G, E224D, V245Q, E248D, T286A, E291D, V292I, I293V, E297A, I329L, F346Y, R356K, G359S, T377L, K385R, K390R, K395R, A400T, K431T, L452K, V458I, D471E, L491S, E492K, E516ED, Q524K, K527Q, E529D, A534S, A554N  
CG-0151-02V CG-0151-02V None None   V35T, T39K, S48T, V60I, K122E, D123S, A158S, T165I, K173T, Q174K, D177E, Q207E, R211K, V245Q, E248D, D250E, A272P, E291D, V292I, I293V, Q334D, G335A, F346G, R356K, G359S, T377M, S379C, K390R, E404D, E432D, V435P, K451R, V466I, S468P, D471E, T477A, H483Q, D488N, L491S, L517I, S519N, A534S, A554S  
CG-0260-02V CG-0260-02V None None   K11T, K20R, V35T, T39N, V60I, D121H, K122E, D123S, I135T, W153R, A158P, D177E, T200A, Q207T, R211K, V245K, A272S, T286A, E291D, V292I, I293V, E297K, K311R, V317A, G335D, R356K, G359S, V381I, T386I, K390R, A400T, T403I, E413D, P421Y, E432D, V435E, G436R, L452M, V467I, D471E, H483Y, S519N, Q524E, A534S, A554S G152V, T439S, F440C 
CG-0331-02V CG-0331-02V None None   I5V, V35T, D121Y, K122E, I142T, S162C, F171Y, K173T, Q174K, D177E, I178M, G196E, T200R, Q207D, R211A, V245Q, D250E, S251D, A272P, T286A, E291D, V292I, I293V, P294T, E297A, P321S, S322T, D324E, I329V, Q334E, G335D, M357R, G359T, K366R, T369A, A371V, A376S, T377L, T386I, K390R, A400T, E404D, V435M, E449D, L452I, R461K, S468T, L469I, T470N, H483Y, L491I, Q524E, K530R, A534S, A554S  
CG-0349-02 CG-0349-02 None None  V179D V35T, S162C, K173I, Q174K, Q207E, R211K, P243T, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, E297V, F346H, G359S, I375V, T386I, A400T, K431T, V435A, L452K, K465H, V466I, D471E, T477A, I482V, H483Q, A502V, S519N, K527Q, K530R, A534S, A554S  
CG-0373-02V CG-0373-02V None None   V35T, T39E, S48T, D123E, A158S, K173A, Q174K, D177E, T200A, Q207E, R211K, V245M, A272P, K277R, T286A, E291D, V292I, I293V, Q330E, Q334N, G335D, R356K, G359T, T377Q, S379C, I380V, A400T, E404D, E432D, V435M, N447NS, L452LI, T459TS, V466I, D471E, H483Q, L491P, E516EG, S519N I329A, K331D, Q332S 
CG-0378-02V CG-0378-02V None None   V8I, V35T, V60I, D121H, K122E, I135V, K173A, P176Q, T200A, Q207A, R211K, V245Q, V276I, L283I, I293V, P294T, L295M, E297K, G335D, R356K, M357K, G359S, K366R, T369V, A371V, I375V, A376S, K390R, T403M, E404D, E432D, V435M, A437V, D471E, Q480H, H483Y, L491P, I495V, K512R, E514D, S519N, Q524K, K527E, A534S, A554S  
CG-0379-02V CG-0379-02V None None   V35T, T39N, V60I, A98S, K104R, D121H, K122E, I135V, A158S, K173A, D177E, T200A, Q207G, R211K, V245K, K281R, T286A, E291D, V292I, I293V, E297A, G335D, F346Y, R356K, M357R, R358G, G359S, A376V, T386M, K390R, A400T, E404D, E432D, V435E, A437V, D471E, Q480H, L491S, L517I, S519N, A534S, A554N  
CG-0382-02V CG-0382-02V None None   V35T, T39A, K43Q, S48T, V60I, V118I, K122E, D177E, I178L, V179T, Q207E, F214L, P243T, V245K, D250E, A272P, T286A, V292I, I293V, Q334Y, F346L, K350R, A376S, T377Q, K390R, E432D, H483N, L517I, A554N  
CG-0536-02 CG-0536-02 None None   P4T, V8I, K11T, V35T, V60I, S68G, T107S, D121H, T139Q, D177E, I178M, T200A, Q207N, R211K, I244V, V245K, K277R, T286A, E291D, V292I, I293V, E297K, Q334E, G359T, I375V, T386I, K390R, A400T, P421H, K431T, V435A, F440Y, V466I, D471E, H483Y, L491P, E492A, S519N, Q524E, A534S, A554S  
CG-0538-02 CG-0538-02 None None   V35T, V60I, T107S, K122E, I142V, D177E, T200A, Q207A, R211G, P243A, I244V, V245K, A272P, K277R, E291D, V292I, I293V, E297K, G335D, M357V, G359T, I375V, T386I, K390R, A400T, V417I, P421H, K431T, V435A, F440Y, L452M, R463K, V466I, D471E, K476R, H483Y, S519N, Q524E, K530R, A534S, V548I, A554S  
CG-0575-02 CG-0575-02 None None   V35T, V60I, T107S, K122P, D123E, S162C, K173T, Q174K, N175Y, I178M, K201R, Q207E, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, L310I, Q334R, G335D, F346Y, R358K, G359S, K390R, A400T, K431T, E432D, V435M, N447H, L452Q, R463G, D471E, T477A, H483N, L491S, E516D, S519N, K527Q, E529D, V531I, A534S, A554N  

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