Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Charpentier (2014)
Title Genotypic resistance profiles of HIV-2-treated patients in West Africa.
Citation AIDS
SelectedGene RT
SelectedSpecies HIV2
SelectedType Clinical
NumIsolates 25
NumPts 25
Host Human

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
001TS 001TS_RT NRTI None M184V, S215Y  M11E, L21I, T27S, K40R, T58S, K102E, E122P, D123N, V135T, A138S, H162Y, E169D, A174T, K176S, I179T, G211N, L212M, D218E, H228Q, I251V, Y271F, K277R, L279I I8V, I10V, E32L, K35N, K82T, I90V, H121D, P126K, T163S, Q166K, T194S, L203S, T237K, Q248E, A267T 
004CP 004CP_RT NRTI None Q151M, M184V  E6Q, M11T, D123E, P126Q, H162Y, I180L, F214L, H228K, E334D, E344G V2I, K4E, I10V, R22K, V167I, K176P, E207Q, L270I, H317C 
006CP 006CP_RT NRTI None M184I  K102E, L109I, E122P, P126Q, H162Y, E169D, K176S, R200K, G211D, L212M, D218E, H228R, I251V, Y271F, L279I, R307K, S311E, H317S, E322G, E324P, E334A, T338S, E344G I90V, I118V, H121D, Q166K, L203S, Y227F, T237K, Q248E, R281K, L303F, E304Q, Q320K, K323V, D332N, Q333L, E345D, ~346. 
017CP 017CP_RT NRTI None M184V, S215Y  L21I, T27S, E32Q, K40KR, T58S, K102S, T107S, E122P, P126Q, H162Y, M164L, R165A, E169D, I179T, R200K, G211N, D218E, E219D, H228K, I251V, Y271F, K277R, L279I, S311E, H317S, E322G, E324P, E334A, E344G K4R, I8IV, I10V, M11K, G15DE, I90V, H121D, T163S, Q166K, V167I, T194S, L203S, L212I, T237K, Q248E, R281K, E304Q, I308T, Q320K, K323IV, D332N, Q333L, E345D, ~346. 
018CP 018CP_RT NRTI None M184V  L21I, T27S, K66R, K102E, K103R, E122P, P126Q, H162Y, E169D, I179T, G211D, H228K V5I, I8V, I10V, M11K, E32L, I90V, I118V, H121D, S134A, E139G, R165G, Q166K, K176G, T194S, E207Q, L212I, Y227F, T237K, Q248E 
019CP 019CP_RT NRTI None M184V  L21I, T27S, K66R, K102E, E122P, P126Q, A138T, H162Y, E169D, I179T, G211S, D218E, H228K V5I, I8V, I10V, M11K, E32L, I90V, I118V, H121D, T163S, Q166K, K176N, I189V, T194S, L212V, Y227F, T237K, Q248E, I251S 
021CP 021CP_RT NRTI None M184V, S215Y  M11Q, L21I, T27S, K35R, K40R, R78RK, E79EK, K102E, K103R, E122P, D123N, P126Q, H162Y, K176S, I179T, L212M, H228Q, L246I, K249R, I251V, Y271F, K277R, H278N, L279I, R284K, L303M, R307K, S311G, H317S, E322G, E324P, E334A, E344G, K347R V2M, V5I, I8V, I10V, E32L, H121D, T163S, Q166K, I189V, T194S, L203S, Y227F, T237K, Q248E, R281K, K286R, M287L, Q320K, K323V, D332N, Q333L, E345N, ~346. 
043TS 043TS_RT NRTI None   L21I, T27S, K102E, E122P, P126Q, R165L, E169D, R172K, K176S, I179T, G211D, H228Q, I251R, Y271F, K277R, L279I, R307K, S311E, H317S, E322G, E324P V5I, I8V, I10V, M11K, E32L, T60V, I75V, V83A, D86EG, I118V, H121D, T163S, Q166K, I189V, T194S, L203S, N210H, L212I, Y227F, T237K, Q248E, A268S, P272M, R281K, E304Q, Q320K, K323V, D332N 
103CP 103CP_RT NRTI None   M11T, R125K, P126Q, V135T, I180L, H228Q, R307K, E334D V2I, V5I, I10V, R22K, E49V, V167I, K176P, L270I, H317C, Q330I 
106CP 106CP_RT NRTI None M184V  I63V, K64R, K102E, T107S, L109I, E122P, P126Q, V135T, A138S, H162Y, R200K, G211N, L212M, D218E, H228R, I251V, Y271F, L279I, R307K, S311E, H317S, E322G, E324P, E334A, E344G, K347R I90V, H121D, T163S, Q166K, K176E, T194S, L203Y, E207Q, T237K, Q248E, A268S, R281K, E304Q, Q320K, K323V, D332N, Q333L, E345D, ~346. 
108CP 108CP_RT NRTI None M184V, S215FY  L21I, T27S, K40R, K102E, K103R, E122P, D123E, P126Q, A138T, H162Y, E169D, P170PS, I179T, G211D, L212M, D218E, E219D, H228K, K249R, I251R, Y271F, K277R, L279I, R284K, R307K, S311E, H317S, E322G, E324P, E334A, E344G, K347R V5I, I8V, I10V, M11KR, E32L, I90V, I118V, H121D, T163S, Q166K, K176E, I189V, T194S, Y227F, T237K, Q248E, L303F, E304Q, Q320K, K323I, D332N, Q333L, E345N, ~346. 
CB017 CB017_RT NRTI None M184V  M11T, L109V, V111I, D123E, P126Q, H162Y, I180L, D195X, R200K, H228R, I251V V5I, I10V, R22K, P51S, R104K, T163S, V167I, K176P, Y227F, L270I 
CB024 CB024_RT NRTI None   M11E, L21I, T27S, K28R, K35R, K66R, T84X, K102R, T107S, E122P, D123DN, P126Q, V135T, H162Y, E169D, K176S, I179T, G211D, L212M, D218E, H228K, I251V, Y271F, K277R, L279I V5I, I8IV, I10V, E32L, V83Y, I90V, H121D, T163S, Q166K, T194S, L203S, T237K, Q248E, R281K 
CB035 CB035_RT NRTI None I75IM, Q151M, M184V, S215F  L21I, T27S, K40KR, K102E, K103R, E122P, D123E, P126Q, A138T, H162Y, E169D, K176S, I179T, R200K, G211N, D218E, H228K, Y271F, K277R, L279I, R284K, R307K, S311E, H317S, E322G, E324P, E334A I8V, I10V, M11K, E32L, V83VA, I90V, I118V, H121D, Q166K, I189V, T194S, L212I, D224E, Y227F, T237K, Q248E, I251K, L303F, E304Q, Q320K, K323I, V329I, D332N, Q333L 
CB043 CB043_RT NRTI None M184I  M11T, K20R, E39D, R78RK, P126Q, H162Y, T163TI, I180L, H228Q, I244L, I251R, R307K V5I, I10V, R22K, D76E, N81T, R104K, A138M, K176P, D195G, Y227F, L270I, H317Y, E324D 
CB052 CB052_RT NRTI None Q151M, M184V  E6K, M11T, D86E, R125K, P126Q, V135T, I145IM, H162Y, I180L, H228Q, I251V, E334D V2I, I10V, R22K, E32D, H121D, E122EK, V167I, K176P, L270I, R281K, H317C, Q330L 
CB063 CB063_RT NRTI None M184V  L21I, T27S, K66R, K102E, K103R, E122P, D123E, A138T, I179T, R200K, G211D, L212M, D218E, H228K, K238R, I251V, Y271F, R307K, S311E, H317S, E322G, E324P, E334A, E344G, K347R I8V, I10V, M11K, E32L, I90V, H121D, T163S, R165RG, Q166K, K176D, I189V, T194S, L203F, E207Q, Y227F, T237K, Q248E, A268S, R281K, Q320K, K323V, D332N, Q333L, E345N, ~346. 
CB069 CB069_RT NRTI None K70N, M184V  L21I, T27S, K43R, K102E, K103R, E122P, P126Q, H162Y, E169D, I179T, G211D, L212M, D218E, H228K, K249R, Y271F, K277R, L279I V5I, I8V, K9R, I10V, M11K, E32L, I90V, H121DN, T163S, Q166K, K176N, I189V, T194S, Y227F, T237K, Q248E, I251NS, A268S 
MI004 MI004_RT NRTI None M184V  M11T, K20R, E39G, T58S, K64R, R78RK, K82R, P126Q, I180L, R200K, H228Q, E250EK, E334D, T338A, E344G I10V, R22K, R104RK, Y146YC, T163M, V167I, K176P, V178VI, Y227F, L270I, D332S, ~346. 
MI006 MI006_RT NRTI None K65R, K70KR, Q151M, M184V  M11T, K35R, K64R, V111I, P126Q, H162Y, I180L, R200K, K223KR, H228Q, T237TN, I244L V5I, I10V, R22K, R104K, K176P, D195G, V263I, L270I 
MI015 MI015_RT NRTI None Q151M  P1L, V2L, K35KR, V111I, D123G, P126Q, V135T, H162Y, R172RK, A174AT, F214L, D218E, H228Q K9E, I10V, M11K, E32D, Q91QR, V167I, K176P 
MI018 MI018_RT NRTI None D67N, K70N, Y115F, M184V  L21I, T27S, K35R, E44D, K102E, E122P, P126Q, H162Y, E169D, K176KQ, I179T, R200K, G211N, L212M, D218E, F221L, H228K V5I, I8V, I10V, M11K, E32L, I90V, I118V, H121D, T163S, Q166K, I189V, T194S, Y227F, T237K 
US014 US014_RT NRTI None K65R, D67DN  M11T, P126Q, H162Y, I180L, R200K, H228Q, I244L V5I, I10V, R22K, N69T, I75V, R104K, V111VIM, K176P, D195G, Y227F, I251K, L270I 
US025 US025_RT NRTI None   L21I, T27S, K28KR, K102E, T107S, E122P, P126Q, V135T, A138S, H162HY, E169D, K176S, G211N, L212M, D218E, H228K, I251V V5I, I8V, I10V, M11K, E32L, P51S, I90V, I118V, H121D, R165S, Q166K, T194S, L203S, T237K, Q248E 
US068 US068_RT NRTI None A62V, K65R, M184V  L21I, T27S, K35R, K64KR, N69NS, K102E, K103R, E122P, P126Q, A138T, H162Y, R165A, E169D, K176S, I179T, G211S, D218E, E219D, H228K, I251T, Y271F, K277R, L279I, T296S, R307K K4R, V5I, I8V, I10V, M11K, E32L, I90V, I118V, H121D, T163S, Q166K, I189V, T194S, L212I, Y227F, T237K, Q248E, R281K, L303Y, E304Q