Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Charurat (2012)
Title Characterization of acute HIV-1 infection in high-risk Nigerian populations.
Citation J Infect Dis
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 14
NumPts 14
Subtype CRF02_AG, G

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
06NG.SC11 06NG.SC11 None None   V35T, I135V, S162A, K173T, Q174K, D177E, I178M, T200E, Q207E, R211K, P243H, V245E, E248D, D250N, K275R, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357K, G359S, A371V, I375A, V381I, K390R, K395R, T403M, E432D, V435A, D471E, Q480H, L491S, K512R, S519N, Q524K, K527E, E529D, A534S, A554N  
07NG.SC12 07NG.SC12 None None   V35T, V60I, K122E, D123E, I135T, S162A, K173T, Q174K, D177E, T200A, I202V, Q207E, V245Q, D250E, K281R, T286A, E291D, V292I, P294T, S322T, G335D, R356K, M357R, G359S, A371V, I375V, T377M, K390R, T403M, E413D, V435M, D471E, Q480H, H483L, L491S, K512R, L517V, S519N, Q524K, K527E, E529D, A554N P433A 
08NG.SC13 08NG.SC13 None None   V35T, T39A, E40D, K173M, Q174K, D177E, Q197K, T200E, R206K, Q207E, R211K, V245Q, E248D, D250E, T286A, E291D, V292I, I293V, K311R, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, S379G, T386V, Q394R, A400V, E413D, K431T, V435L, F440Y, R461K, R463K, V466I, V467I, S468T, L469I, T470Q, D471E, Q480H, H483L, Q487K, L491S, K512R, S519N, A534T, A554S  
09NG.SC20 09NG.SC20 None None   K20R, V35T, V60I, D121Y, K122E, D123G, I142T, K173T, Q174K, D177E, T200V, R211K, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297K, I329V, Q334P, G335E, F346Y, R356K, M357R, R358G, G359S, T386V, Q394R, A400V, E413D, Q428R, K431T, V435T, F440Y, N447S, R461K, R463K, V467I, S468T, L469I, T470Q, D471E, T477A, Q480H, H483Q, L484I, L491P, I495IT, K512R, S519N, Q524E, A534T, A554S  
09NG.SC21 09NG.SC21 None None  V106I V35T, T39N, E40D, V60I, K122E, D123E, Q174D, D177E, I178M, T200A, Q207E, R211K, F214L, V245Q, E248D, D250E, S251A, A272P, K281R, T286A, E291D, V292I, I293V, P294S, E297A, L301M, P321S, D324E, I329V, Q334P, G335E, P345Q, F346Y, R356K, M357R, R358G, G359S, A371V, T386I, K390R, Q394R, A400L, V417I, K431T, V435P, F440Y, V466I, V467I, S468T, D471E, T477A, Q480H, H483Q, L491S, E492A, K512R, L517I, S519N, K527N, V531I, A534S, V548I, A554N, V559I  
09NG.SC24 09NG.SC24 None None   P4S, K20R, K30KE, V35T, E36D, T39A, K122E, I135V, S162A, K173T, Q174R, D177E, T200E, Q207E, V245Q, E248D, S251C, K281R, T286A, E291D, I293V, P294T, S322A, G335D, R356K, M357K, R358K, G359S, K366R, A371V, I375V, K390R, K395R, T403M, E432D, D471E, Q480H, L491S, K512R, S519N, Q524E, E529D, A534S, A554S  
09NG.SC26 09NG.SC26 None None K65KE  G15GR, K32R, V35T, E40D, V60I, K104R, K122E, D123S, S162A, K173T, Q174A, D177E, I195T, T200A, Q207D, V245Q, E248N, S251T, A272P, K281R, T286A, E291D, V292I, I293V, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, A371V, A376S, T386V, Q394R, A400V, K431T, V435A, F440Y, R461K, R463K, V467I, S468T, L469I, T470Q, D471E, Q480H, H483K, L491P, L503I, K512R, S519N, A534T, A554S W383W* 
09NG.SC27 09NG.SC27 None None   V21I, V35T, E36D, V60I, I135V, S162A, K173A, Q174E, T200A, E204K, Q207E, R211K, V245Q, E248D, D250E, K277R, T286A, E291D, V292I, I293V, R307K, S322A, I326V, M357K, G359S, K366R, T369V, A371V, I375V, A376G, A400T, T403M, W410Y, E432D, D471E, Q480H, L491S, K512R, S519N, Q524K, K527E, A534S, A554S  
09NG.SC28 09NG.SC28 None None M184I M230I M16I, V35T, M41I, K49R, W71*, W88*, G112E, D123E, R125K, I135V, G141E, R143K, W153*, G155R, S162A, E169Q, K173T, Q174E, G190R, G196R, T200A, Q207G, R211K, W212*, W229*, W239*, V245Q, I257V, T286A, E291D, V292I, I293V, P294T, E297T, G316R, S322T, I326V, G335D, W337*, R356K, M357K, G359S, A360T, A371V, I375V, W383*, K390R, W398*, W401*, W402*, T403M, W410*, E413D, W414*, V435I, R448K, G453R, G456E, D471E, Q480H, L491S, L517I, S519N, Q524K, K527R, E529D, A534S, W535*, A554S, G555R G93K, G273E, G384R, G444R 
09NG.SC29 09NG.SC29 None None   V35T, E36D, I135V, S162A, K173T, D177E, I178V, T200A, Q207G, R211K, V245L, T286A, V292I, I293V, P294T, S322T, I326V, R356K, M357K, R358G, G359S, A371V, I375V, A376T, T377R, K390R, K395R, A400T, T403M, E432D, D471E, Q480H, L491S, K512R, S519N, Q524K, K527E, E529D, K530R, A534S, A554S  
09NG.SC30 09NG.SC30 None None   V21I, V35T, T39M, V60I, I135T, S162A, K173T, Q174E, D177E, I178M, T200A, Q207K, R211S, E224K, V245T, T286A, E291D, V292I, I293V, P294T, S322T, G335D, R356K, M357R, G359S, A371L, I375V, T377I, K390R, T403M, E413D, E432D, V435A, D471E, Q480H, L491S, K512R, S519N, Q524K, K527E, E529D, A534S, A554S  
09NG.SC31 09NG.SC31 None None   V35T, E40D, K49R, V60I, D121H, K122E, D123N, S163T, K173V, Q174K, D177E, T200A, Q207E, R211K, V245Q, E248N, A272P, T286A, E291D, V292I, I293V, D320N, D324E, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, E370D, A371I, T386V, Q394K, A400V, W402*, Y405H, K431P, V435P, F440Y, R461K, R463K, V466I, V467I, S468T, L469I, T470Q, D471E, Q480H, H483Q, L491S, K512R, S519N, A534T, A554N T409I 
09NG.SC61 09NG.SC61 None None   K11R, V35T, E36D, K122P, I135V, S162A, K173A, Q174K, D177E, I178V, I180V, T200A, Q207E, F214L, V245Q, E248D, D250E, K277R, T286A, E291D, V292I, I293V, S322T, I326V, G335D, R356K, M357K, G359S, A371V, I375V, A376S, T377M, K390R, E399D, T403M, E413D, V435A, S468P, D471E, S489A, L491S, K512R, S519N, Q524E, E529D, K530R, A534S, A554S  
09NG.SC62 09NG.SC62 None None  V106I E28K, K32E, V35T, T39M, V60I, K122E, D123N, K173T, Q174K, D177E, I178L, T200A, R211K, V241I, V245K, E248D, D250E, S251D, A272S, T286A, E291D, V292I, I293V, K311R, P321S, D324E, I329V, G333E, Q334P, F346Y, R356K, M357R, R358G, G359S, Q367E, A371V, A376S, T377I, T386I, K390R, Q394K, E399D, A400V, E413D, Q428R, K431T, V435A, F440Y, E449K, D460N, G462E, R463K, V466I, S468T, L469I, T470Q, D471E, Q480H, H483Q, L491P, K512R, L517I, S519N, A534T, Q547K, A554S G352E 

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