Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Leoz (2011)
Title Circulation of multiple patterns of unique recombinant forms B/CRF02_AG in France: precursor signs of the emergence of an upcoming CRF B/02.
Citation AIDS
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 5
NumPts 5
Subtype CRF02_AG, B, CRF56_cpx

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
URF1 URF1 None None   K49R, K103R, K122E, I135T, I178M, T200A, E204K, R211Q, A272P, T286A, E312D, I326V, G335D, R356K, M357K, G359S, R448K, L452A, R461K, T470N, K476R, A554T  
URF2 URF2 None None   P4PS, V35T, S48T, K49R, V60I, I135V, S162A, K173I, Q174K, D177E, T200A, Q207E, R211K, V245I, A272P, K275Q, E291D, V292I, I293V, P294T, S322A, I326V, G335D, F346Y, R356K, M357R, G359S, K366R, A371V, I375V, A376T, V381I, K390R, K395R, A400T, T403M, E432D, N447S, T450TS, L452I, V467VI, T470N, D471E, Q480H, L491S, S519N, Q524K, K527E, E529N, A534S  
URF3 URF3 None None   K49R, V60I, D123E, I135L, T139I, D177E, R211K, V245K, E305K, V317A, I329L, R356K, A360T, K366R, T377M, Q394P, A400T, E404D, E432D, V435A, R461K, L469I, D471E, Q480H, H483L, L491S, K512R, S519D, Q524K, K527G, E529D, A534S, A554N, K558R  
URF4 URF4 None None   V8I, V35T, T39A, E40D, K102KR, I135V, S162A, K173T, Q174K, D177E, T200A, I202V, Q207E, R211K, V245Q, T286A, E291D, V292I, I293V, P294V, E300EK, E312Q, S322T, G335D, R356K, M357K, G359S, A371V, I375A, T377L, K390R, K395R, E432D, A437V, T470A, D471E, Q480H, H483Y, L491S, K512R, S519N, Q524K, K527E, E529N, A534S, A554N, K558R  
URF5 URF5 None None   P4H, K11S, V35T, T39K, E40D, M41V, K49R, D123E, I135T, T165I, Q174H, G196R, I202V, R211K, F214L, V245Q, E248D, A272P, K277R, E297A, S322T, R356K, M357T, K366R, A376T, V381I, A400T, E432D, L452I, D471E, Q480H, H483Y, L491S, L517V, A534S, V548I, A554S, K558R  

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