Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Mulu (2015)
Title Lack of integrase inhibitors associated resistance mutations among HIV-1C isolates.
Citation J Transl Med
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 43
NumPts 43
Subtype C

 

Clinical IN Isolates


SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
ETH-G-5479 ETH-G-5479 None    A21AS, S24N, D25E, V31I, G47GR, L74I, S81SR, F100Y, L101I, G106A, T112V, S119A, T124N, T125A, G163E, K188R, V201I, I203M, K215N, L234I, L242LI, W243X, D253DE I257IR 
ETH-G-5485 ETH-G-5485 None    S17N, A21AS, M50I, F100Y, L101I, T112V, T124A, T125P, K136Q, V201I, T218I, I220V, L234I, R269K K186K* 
ETH-G-5492 ETH-G-5492 None   E157Q Y83YF, E87K, A91AT, T93TA, E96D, F100Y, L101M, G106A, T112V, T124N, T125A, K136Q, K156N, V201I, K215N, T218L, L234I A86AT, Y99S 
ETH-G-5493 ETH-G-5493 None    S17N, S24D, D25E, L45V, M50I, L101I, T112V, T124A, T125V, K136Q, G163GE, K211KR, Y227F, L234I V77E_NSRIPYTPPP, W243WG 
ETH-G-5496 ETH-G-5496 None    I72V, F100Y, L101I, T112V, T124S, T125A, K136Q, D167E, K188R, V201I, I203M, K215N, T218L, L234I, V260L, R269K Q44QR, Q53E, L158LS, I267N 
ETH-G-5497 ETH-G-5497 None    S24N, D25E, I72V, F100Y, L101I, T112V, T124A, T125A, K136Q, F181L, V201I, T218I, L234I  
ETH-G-5499 ETH-G-5499 None    S24N, D25E, V31I, L74I, F100Y, L101I, G106A, T112V, S119A, T124N, T125A, G163E, K188R, V201I, I203M, K215N, L234I  
ETH-G-5511 ETH-G-5511 None    R20RK, S24N, D25E, V31I, I84M, F100Y, L101I, T112X, T125A, K136Q, E138X, V151X, Q164H, A169X, M178X, A196P, R199K, V201I, K215N, T218L, L234I, A265X G163W 
ETH-G-5517 ETH-G-5517 None    S24N, D25E, V31I, F100Y, L101I, T112V, T124N, K136R, K173R, K188R, I191L, I200X, V201I, T206S, K215N, Q216K, T218L, K219Q, L234I D202G, K264S, A265Q 
ETH-G-5524 ETH-G-5524 None    E11A, S24N, D25E, V31I, I60V, I72V, I84M, L101I, T112V, T125V, V150A, V165I, V201I, K211R, K215N, T218L, L234I  
ETH-G-5525 ETH-G-5525 None    E11A, S24N, D25E, V31I, I60V, I72V, I84M, L101I, T112V, T125V, V150A, V165I, V201I, K211R, K215N, T218L, L234I  
ETH-G-5530 ETH-G-5530 None    V31I, F100Y, T112V, T124N, T125A  
ETH-G-5531 ETH-G-5531 None    S24N, D25E, S57N, I72V, I84M, A91G, F100Y, L101I, T112V, T124S, T125A, D167E, K173R, G192A, V201I, K215N, T218L, N222K, L234I  
ETH-G-5544 ETH-G-5544 None    S24N, D25E, V31I, L74I, F100Y, L101I, G106A, T112V, T124A, T125A, K136Q, F181L, V201I, T218I, L234I  
ETH-G-5546 ETH-G-5546 None    S24D, D25E, V31I, L101I, T112V, T124N, V201I, K211R, K215N, Q216K, T218L, K219N, N222K, L234I, L242LI, A265V  
ETH-G-5550 ETH-G-5550 None    S24N, D25E, V31I, L74I, F100Y, L101I, G106A, T112V, F121X, A128X, D167E, F185L, K188R, R199K, V201I, T206S, D207E, K215N, T218L, L234I, K264* T122~, S123~, T124~, T125~, V126~, K127~, V225D 
ETH-G-5551 ETH-G-5551 None    N18X, S24N, D25E, V31I, I84LM, F100Y, L101I, T112V, S119P, T124N, T125A, D167E, K188R, R199K, V201I, T206S, D207E, K215N, T218L, L234I H12HL 
ETH-G-5568 ETH-G-5568 None    D25E, V31I, L101I, T112V, T124A, T125A, K136Q, G163V, A205T, T218I, L234I  
ETH-G-5572 ETH-G-5572 None    K14R, S24N, D25E, V32I, S39C, L101I, T112V, K136Q, V165I, D167E, K173R, V201I, T218L, L234I  
ETH-G-5582 ETH-G-5582 None    D25E, P30A, L45I, M50L, L101I, T112V, S119P, T124S, T125A, I135V, K156N, V165I, V201I, K211R, T218I, I220V, L234I  
ETH-G-5585 ETH-G-5585 None    S17N, A21AS, M50I, F100Y, L101I, T112V, T124A, T125P, K136Q, R187RK, V201I, I220V, L234I, R269K K186K* 
ETH-G-5592 ETH-G-5592 None    S24N, D25E, M50T, F100Y, L101I, T112V, T124S, T125A, K136Q, V201I, K215N, T218L, L234I V260VG 
ETH-G-5595 ETH-G-5595 None    F100Y, T112V, T124N, T125A, K215N, T218L, L234I, A265V  
ETH-G-5596 ETH-G-5596 None    S24N, D25E, V31I, L74I, F100Y, L101I, G106A, T112V, T124N, T125A, G163E, K188R, V201I, I203M, K215N, L234I V260VG 
ETH-G-5604 ETH-G-5604 None    R20RK, S24N, D25E, V31I, I84M, F100Y, L101I, T112X, T125A, K136Q, E138X, V151X, Q164H, A169X, M178X, A196P, R199K, V201I, K215N, T218L, L234I, A265X G163W 
ETH-G-5630 ETH-G-5630 None   T97A S24N, D25E, V31I, M50L, I60X, Q62X, V79A, V88L, A91E, E92K, G94X, E96EG, F100CY, L101T, T112V, T115A, T122TA, T124N, T125A, D167E, K188R, I191L, G193E, V201I, K215N, T218L, L234I, R269K S57I, A86P, E87Q, Y99DEG, I113IR, K127KE, V249VE 
ETH-G-5642 ETH-G-5642 None    S17SR, V31I, L45LV, I60X, L101I, T112V, T124N, T125A, G163E, V201I, K215N, T218L, L234I, L242LI, D253DE, S255Q, A265S I217IKN, V225VI 
ETH-G-5648 ETH-G-5648 None    E11D, S24N, D25E, V31I, I72V, F100Y, L101V, T112V, T124N, T125A, V201I, K215N, T218L, L234I, D253E, A265V, R269K V249VE 
ETH-G-5655 ETH-G-5655 None    S24N, D25E, V31I, F100Y, L101I, T112V, T124S, T125A, K136Q, K188R, V201I, K215NS, I217V, T218L, L234I  
ETH-G-5669 ETH-G-5669 None    E35K, F100Y, L101I, T112V, T124N, T125A, K136Q, V201I, K215N, T218L, I220IV, L234I, N254NK  
ETH-G-5672 ETH-G-5672 None    D6E, S24N, D25E, I72IV, F100Y, L101I, K111KR, T112V, S119P, T124N, T125A, K136R, D167E, K173R, K188R, I191L, V201I, I203M, K215N, T218L, I220V, L234I, R269K A76S 
ETH-G-5681 ETH-G-5681 None    D25E, V31I, L74M, L101I, T112V, T124A, T125A, G134GD, K136Q, G163V, T218I, L234I  
ETH-G-5690 ETH-G-5690 None    K7KR, D25E, V31I, M50I, I72V, F100Y, L101I, T112V, T124A, T125A, K136Q, K188KR, G193GE, V201I, T218I, L234I, I251L, A265V, R269K  
ETH-G-5712 ETH-G-5712 None    S24N, D25E, V31I, I84IM, F100Y, L101I, T112V, S119P, T124N, T125A, D167E, K188R, V201I, T206S, D207E, K215N, T218L, L234I  
ETH-G-5717 ETH-G-5717 None   T97TA V31I, F100Y, T112V, T124N, T125A, K215N, T218L, L234I, A265V V259VG 
ETH-G-5732 ETH-G-5732 None    E11D, R20K, D25E, V31I, S39N, I72V, L101I, T112V, T125V, K136KN, D167E, K173R, G193E, K215N, T218L, L234I V201IK 
ETH-G-5733 ETH-G-5733 None    S24N, D25E, I72V, F100Y, L101I, T112V, T124A, T125A, K136T, V165I, D167E, V201I, L234I D55DE 
ETH-G-5769 ETH-G-5769 None    D25E, V31I, L101I, T112V, T124A, T125A, K136Q, E152*, G163V, T218I, L234I  
ETH-G-5775 ETH-G-5775 None    D6E, S24N, D25E, V31I, I84M, F100Y, L101I, T112V, S119P, T124N, T125A, K136T, E138X, K188R, I191L, K215N, Q216K, T218L, K219Q, L234I V201IK 
ETH-G-5786 ETH-G-5786 None    V31I, I60L, L101I, T112V, T124N, T125A, G163E, V201I, K215N, T218L, L234I, S255Q  
ETH-G-5790 ETH-G-5790 None    E11D, E13X, S24N, D25E, V31I, I72V, F100Y, L101V, T112V, T124N, T125A, V201I, K215N, T218L, L234I, D253E, A265V  
ETH-G-5837 ETH-G-5837 None    E11A, S24N, D25E, V31I, I60V, I72V, I84M, L101I, T112V, T125V, V150A, V165I, V201I, K211R, K215N, T218L, L234I  
ETH-G-5841 ETH-G-5841 None    E11D, S24N, D25E, V31I, I72V, F100Y, L101V, T112V, T124N, T125A, V201I, K215N, T218L, L234I, D253E, A265V, R269K V249VE 

Database

Resources

Team