Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Ndahimana (2016)
Title Drug resistance mutations after the first 12 months on antiretroviral therapy and determinants of virologic failure in Rwanda.
Citation Trop Med Int Health
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 70
NumPts 70
Subtype A, C, D, B, CRF18_cpx, CRF01_AE

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
1023 1023 TDF, 3TC NVP M41L, K65R, M184V Y181CG, G190GA V90VI, K122E, D123N, S162SA, K173L, Q174K, D177E, I178M, V179I, T200A, Q207A, R211S, V245Q  
1037 1037 TDF, 3TC EFV   T39A, K122E, I142V, K173S, D177E, I178M, V179I, E204K, Q207A, R211S, V245Q  
1107 1107 TDF, 3TC NVP M184V G190A T39M, S48T, V60I, K122E, D123N, I135T, K173S, Q174K, D177E, I178M, V179I, Q207A, R211S, V245N  
1114 1114 TDF, 3TC NVP K65R, Y115YF, M184V V108VI V60I, S68G, D123N, I135T, S162A, K173L, Q174K, D177E, V179I, I180V, Y181X, T200A, Q207A, R211S, V245Q  
1118 1118 TDF, 3TC NVP K65R, Y115F, M184V Y181I E40D, K49R, V60I, K122E, D123N, I135M, K173L, Q174K, D177E, V179I, T200A, Q207A, R211S, V245N  
1119 1119 TDF, 3TC NVP   T39M, S48T, V60I, K122E, D123S, I135T, K173A, D177E, V179I, T200A, Q207A, R211S, V245Q  
1136 1136 TDF, 3TC NVP M184V, K219E K103N K49R, V60I, K122E, D123N, I135T, I142V, K173S, Q174K, D177E, T200A, Q207A, R211S, P243S, I244V  
1140 1140 TDF, 3TC NVP A62AV, K65R, M184V A98AG, V108VI, Y181C, G190GA S68SG, K122E, D123N, I142V, K173L, Q174K, D177E, V179I, T200A, Q207A, R211S, V245E  
1170 1170 TDF, 3TC NVP   K122E, D123N, I135T, I142V, K173L, D177E, I195IT, Q207A, R211S, F214L, V245Q  
1173 1173 TDF, 3TC NVP K65KR, K70KE, M184V, K219KE Y181C, H221HY E40D, K49R, V60I, S68SG, K122E, D123NS, I135T, S162A, K173S, Q174K, I178L, V179I, T200K, Q207A, R211S, F214L, L228LR, V245Q  
1180 1180 TDF, 3TC EFV K65R K103N, Y181C E44D, K104KR, V118I, K122KE, D123N, I135T, T165I, K173S, D177E, I178M, V179I, Q207A, R211S, F214L, V245Q  
1183 1183 TDF, 3TC NVP   K122E, D123N, I135T, I142V, K173L, D177E, I195T, Q207A, R211S, F214L, V245Q  
1199 1199 TDF, 3TC NVP K65R, V75M, Y115F, M184V K101E, G190S T39A, V60I, D121H, K122E, D123S, I135T, I142V, K173S, Q174K, V179I, Q197E, T200A, Q207A, I244V  
1204 1204 TDF, 3TC NVP A62V, K65R, M184V K103N, Y181C T39TA, E44ED, K122E, D123S, I135T, K173S, Q174K, D177E, V179T, T200A, Q207D, R211K, L228LR, P243T, V245E  
1207 1207 TDF, 3TC NVP K65R, M184MIV V108VI, Y181C T39E, E40D, K43R, K104N, D123S, I135IM, K173S, Q174R, D177E, T200A, I202V, Q207E, R211K, F214L, V245Q  
1223 1223 TDF, 3TC NVP L74LI, M184V, K219KE V108I, Y181C V60I, K122E, I135T, K173S, Q174K, D177E, V179I, Q207A, R211S, F214L, V245Q  
1234 1234 TDF, 3TC NVP K65R, Y115F, M184V A98AG, Y181C, H221HY T39KN, V60I, K122E, D123G, I135T, S162A, K173S, Q174K, D177E, V179I, T200AE, Q207A, R211S, V245Q  
1240 1240 TDF, 3TC NVP K65R, M184V V108I, Y181C T39E, E40D, S48T, V90I, K122E, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q  
1246 1246 TDF, 3TC NVP   T39L, V60I, K122E, D123N, I135T, K173S, Q174K, D177DE, V179I, E194Q, G196E, T200A, I202V, Q207A, R211S, F214L  
1250 1250 TDF, 3TC EFV K219R Y181C, G190S T39A, E40D, K101Q, K122E, D123S, I135T, K173S, D177E, V179S, T200TK, Q207A, R211S, F214L, P243S, V245E K65T 
1251 1251 TDF, 3TC NVP K70E, M184V A98AG, Y181C V60I, K101KR, D121H, K122E, I135T, K173S, Q174K, D177E, V179I, T200A, Q207A, R211K, L228R, V245Q  
1275 1275 TDF, 3TC NVP K70KE, L74LI, M184V Y181C, H221Y T39K, V60I, F77S, K122E, D123N, I135T, I142K, K173S, Q174K, V179I, T200A, Q207A, R211S, V245T K49A 
1286 1286 TDF, 3TC NVP   K49R, V60I, K122E, I135IT, Q207E, R211K, V245K  
1289 1289 TDF, 3TC NVP A62V, K65R, M184V L100I, Y181C, G190A, H221Y T39TA, K101R, V111I, K122E, D123S, I135T, I142V, T165I, K173S, D177E, V179I, T200A, Q207A, R211S, V245Q  
1296 1296 TDF, 3TC NVP K70E, M184V A98G, Y181C E40D, V60I, K122E, D123S, I135T, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, L228R, V245Q  
1303 1303 TDF, 3TC NVP   T39K, S48T, V60I, K122E, D123N, A158S, K173A, D177E, T200A, Q207S, V245Q  
1310 1310 TDF, 3TC NVP K65R, M184V K101E, Y181C T39E, E40D, S48T, K122E, I135K, K173A, D177E, T200A, Q207K, R211S, V245Q  
1313 1313 TDF, 3TC NVP   V60I, D121H, K122E, I135T, A158S, K173A, Q174K, D177E, Q207A, R211S, F214L  
1314 1314 TDF, 3TC NVP K65R G190A E40D, K122E, E169D, K173A, Q174K, Q207A, R211S, V245Q  
1318 1318 ABC, 3TC NVP M184MV K103N K43R, K122E, D123N, I135T, I142IV, K173S, D177E, I178IL, V179T, T200A, Q207A, R211S, F214L, V245Q  
1333 1333 TDF, 3TC NVP A62V, K65R, M184V E138EG, Y181IV T39E, K43R, S48T, V90VI, K122E, I135T, S162H, K173A, Q174K, D177E, V179I, T200A, Q207E, R211K, V245M  
1346 1346 TDF, 3TC NVP K65KR, M184V K101KE, Y181C, G190A V60I, K70X, D121H, K122E, D123S, I135T, I142V, K173A, D177E, T200A, Q207E, R211K, V245E  
1415 1415 TDF, 3TC NVP A62AV, K65R, M184V K103N, Y181C T39R, K46KQ, I47IL, K49R, D121H, K122E, I135T, E169D, D177E, T200L, Q207E, R211K, V245Q  
1420 1420 TDF, 3TC NVP K65R, M184V K103N, Y181C T39M, K46Q, I47IL, K49R, V60I, D121Y, K122E, S162X, E169K, K173E, D177E, V179I, G196E, T200A, I202IV, Q207A, R211K, V245Q E44EQ 
1425 1425 TDF, 3TC NVP   E40D, K49R, I50V, V60I, V118I, D121H, K122E, I135T, T139A, I159IV, S162X, K173S, Q174E, D177E, V179I, Q207A, R211S, F214L, V245Q Q145Q* 
1430 1430 TDF, 3TC NVP  E138A, G190A S48T, K49R, K122E, D123N, S162C, K173S, Q174K, D177DE, V179T, T200A, R206RK, Q207AD, R211K, V245Q  
1431 1431 TDF, 3TC NVP   T39E, E40D, K49R, K122E, D123G, I135T, K173T, D177E, I178IM, T200A, Q207E, R211K, V245Q  
1433 1433 TDF, 3TC NVP   T39A, E40D, K122E, D123N, I135T, V179I, T200A, Q207A, R211S, F214L, V245Q  
1435 1435 TDF, 3TC EFV   K122E, D123NS, I135T, S162A, K173S, V179I, Q207A, R211S, V245E  
1441 1441 TDF, 3TC NVP D67N, K70E, M184V G190GA, H221Y T39A, E40D, E44D, K122E, D123S, I142V, S162AT, K173S, D177E, V179I, Y181X, I195L, T200A, Q207A, R211S  
1445 1445 TDF, 3TC NVP K65R, M184V, K219E K101E, Y181C, G190A T39A, K43R, V60I, S68G, I135T, T165I, K173A, Q174K, N175H, D177E, T200A, I202V, Q207A, R211K, V241I  
1493 1493 TDF, 3TC NVP K65KR, M184V A98AG, V108VI, Y181C, H221HY T39TI, E40D, K49R, V60I, K122E, D123S, I135T, K173S, Q174K, D177E, V179I, T200E, Q207A, R211S, V245Q  
1499 1499 TDF, 3TC NVP  K103N K49R, V60I, K122E, D123S, I135T, T139A, K173S, Q174K, D177E, V179I, Q207A, R211RS, V245Q  
1500 1500 TDF, 3TC NVP M184V K103N V60I, K122E, D123S, I135T, K173S, Q174K, D177E, T200A, Q207A, R211S, V241I, V245K  
1503 1503 TDF, 3TC NVP  G190A T39D, K122E, D123S, A158S, K173A, D177E, T200A, Q207E, R211RK, V245Q  
1504 1504 TDF, 3TC NVP   V60I, K122KE, I135T, K173S, Q174K, D177E, I178IM, V179I, T200A, Q207A, R211S, F214L, V245E  
1506 1506 TDF, 3TC NVP A62V, K65R, M184V Y181C T39A, K122E, D123S, I135T, T139KR, I142V, K173S, Q174K, D177E, V179I, T200A, E204Q, Q207E, R211K, F214L, L228Q  
1520 1520 TDF, 3TC NVP A62V, K65R, V75I, M184V Y181C, G190A T39A, E40D, K46Q, T58S, S68N, K122E, D123N, I135T, I142V, S162SN, K173S, D177E, I178IM, V179I, T200A, I202V, Q207A, F214L, V245Q  
1524 1524 TDF, 3TC NVP K65R, K70KE, M184V A98AG, K103KN, V108VI, Y181C, H221Y T39L, I50V, V60I, S68SN, K122E, D123S, I135T, I142V, K173S, Q174K, V179I, G196E, Q207A, R211S, F214L, V245Q  
1531 1531 TDF, 3TC EFV M184I L100I, K103N E40D, K43N, K49R, V60I, V90VI, K122E, I135T, I142V, S162A, T165M, D177E, I178M, T200I, Q207E, R211K, V245Q  
1533 1533 TDF, 3TC EFV   K122E, D123N, T139TA, K173S, D177E, V179I, T200A, I202IV, Q207A, R211S, F214L, P243T, V245Q  
1536 1536 TDF, 3TC NVP M184V G190A V60I, V90I, D121H, K122E, I135T, K173S, Q174K, D177E, V179I, T200A, I202V, Q207A, R211S, V245E  
823 823 TDF, 3TC NVP  K101KE K49R, I50V, V60I, K122E, D123S, I135T, K173L, Q174KR, D177DE, Q207D, F214FL, V245Q  
826 826 TDF, 3TC NVP  K103N T39TI, K43KN, K49KR, V60I, K122P, I142IV, K173AT, Q174K, D177E, V179I, G196E, T200R, Q207E, R211K, P243T, V245Q  
837 837 TDF, 3TC NVP M184V, K219KE A98G, Y181C T39R, V60I, D123N, K173A, D177E, V179I, T200E, I202V, Q207A, R211K, V245Q  
840 840 TDF, 3TC EFV   T39K, S48T, D123E, T139A, K173R, D177E, I195L, Q197H, T200A, Q207E, R211K, F214L, V245Q  
852 852 AZT, 3TC NVP  K103KN V60I, K122E, D123N, I135T, S162A, K173S, Q174K, D177E, V179I, Y188X, T200I, E203D, Q207A, R211S  
859 859 TDF, 3TC NVP   E40D, K49R, V60I, K122E, D123G, I135T, K166KR, K173L, Q174K, D177E, V179I, Q207A, R211S, V245Q  
868 868 TDF, 3TC NVP K65R, K70R K103N, Y181C T39A, E40D, V60I, K122E, D123S, I135T, S162A, K173S, Q174K, D177E, Q207A, R211S, F214L, V245Q  
869 869 TDF, 3TC NVP A62V, K65R, Y115F, M184V Y181C T39E, K122E, D123S, I135R, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q  
874 874 TDF, 3TC NVP  K103T E40D, S48T, K49R, V60I, K122E, E169D, Q207E, R211K, V245E  
875 875 TDF, 3TC NVP K65R V106A, F227L V60I, K122E, D123N, I135T, I142V, K173S, Q174K, D177E, Q207A, R211K  
930 930 TDF, 3TC NVP M184V Y181C S48T, T69S, K122E, D123S, I135T, I142V, K173S, D177E, V179I, Q207A, R211S, D218DE, L228LR, V245Q  
934 934 TDF, 3TC NVP K65R, M184V Y181I S68SG, K122E, D123N, S162C, K173I, Q174K, D177E, V179I, I202IV, Q207A, R211S, V245Q  
937 937 TDF, 3TC NVP K70E, M184V Y181C, H221Y T39S, E40Q, K43N, V60I, V90VI, K122E, D123NS, T139R, K166R, K173S, Q174N, D177E, I178M, V179I, T200A, I202V, Q207A, R211K, V245E  
953 953 TDF, 3TC NVP K65R, M184MV K103N, E138A, M230L T39E, S48T, T69S, K122E, D123S, A158S, K173T, D177E, E194D, T200E, F214L, V245Q  
957 957 TDF, 3TC NVP K65R, M184I Y181C K49R, V60I, V90I, K101KR, K122E, D123N, I135T, I142V, W153R, S162A, K173A, Q174K, D177E, V179I, I195L, T200A, I202IV, Q207A, R211S, V245Q  
961 961 TDF, 3TC NVP K65R, M184V K101KE, Y181C, G190A T39M, I47L, V60I, S68SN, V90VI, K122E, K173S, Q174K, V179I, Q197E, T200A, E204D, Q207A, R211S  
968 968 TDF, 3TC EFV  V106A T39A, K122E, D123G, I135T, K173L, Q174K, D177E, V179I, T200A, I202V, Q207A, R211S, F214L, V245Q  
978 978 TDF, 3TC EFV   T39L, V60I, K102R, K122E, D123S, I135T, S162A, K173L, Q174K, D177E, G196E, Q207A, R211S, F214L, V245M  

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