Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Palm (2015)
Title Cocirculation of several similar but unique HIV-1 recombinant forms in Guinea-Bissau revealed by near full-length genomic sequencing.
Citation ARHR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 6
NumPts 6
Subtype CRF02_AG

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
DL3039 DL3039 None None  E138A V35M, E36D, V60I, S68G, K102E, K122E, I135V, S162A, K173R, Q174K, D177E, T200A, Q207D, V245Q, T286A, E291D, V292I, I293V, P294V, S322T, I326V, G335D, R356K, M357K, G359S, K366R, A371V, I375V, T377A, K390R, K395R, T403M, E432D, V435A, V466A, D471E, Q480H, H483Y, L491S, K512R, L517I, S519N, Q524K, K527E, E529D, A534S, G541X, A554S L295P 
DL3234 DL3234 None None   V35A, T39A, E40D, V60I, S68G, R72G, I135R, A158S, S162A, K173T, Q174K, I178M, G196E, T200A, Q207G, R211T, K238E, P243S, V245Q, D250E, T286A, I293V, P294T, S322T, G335D, I341V, R356K, M357R, G359S, A371V, I375V, A376S, T377L, K390R, T403M, E432D, V435A, T450N, V467I, S468T, D471E, Q480H, H483Y, L491S, I495V, L517I, S519N, K527G, A534S, A554S, I556V  
DL3773 DL3773 None None   V35T, E36D, K122E, K154X, S162A, E169Q, K173E, Q174E, D177E, T200A, Q207E, L228P, V245Q, A272P, T286A, E291D, V292I, I293V, R307K, D320N, S322T, I326V, Q332R, G335D, R356K, M357K, R358K, G359S, A371V, I375V, K390R, T403M, E432D, V435R, K465M, D471E, Q480H, L491S, I505V, K512R, L517I, V518A, S519N, Q524K, K527E, A534S, A554S  
DL4186 DL4186 None None   V35T, T39S, D123E, I135V, S162A, K173T, Q174N, D177E, T200A, Q207K, R211K, V245Q, T286A, E291D, V292I, I293V, P294A, E298G, A304V, S322T, I326V, G335D, R356K, M357K, G359S, K366R, T369A, I375V, T377I, K388R, K390R, K395R, A400T, T403M, E432D, V435A, L452I, D471E, Q480H, H483L, L491S, K512R, S515V, S519N, Q524K, K527E, E529D, V531I, A534S, A554S L120I 
DL5308 DL5308 None None   E36D, K49R, K101Q, I135V, S162A, K173R, Q174K, D177E, T200A, E204D, Q207A, R211K, P243S, V245Q, V261I, A272P, T286A, E291D, I293V, P294T, S322T, G335D, R356K, M357R, G359S, A371L, I375V, K388R, K390R, K395R, T403M, E432D, V435A, E449K, L452V, R461K, V466I, L469I, D471E, Q480H, H483Y, L491S, Q507H, A508S, K512R, S519N, Q524K, K527E, E529D, A534S, A554N L303S 
DL5918 DL5918 None None   V35M, E36D, T39K, K43E, K66R, D123E, I135V, A158S, S162A, K173R, Q174K, D177E, V179I, T200A, E204D, Q207E, R211S, I244V, V245Q, D250E, T286A, E291D, V292I, I293V, P294A, E297K, S322T, I326V, G335D, M357K, G359S, A371V, I375V, A376T, K390R, T403M, E432D, N447S, R463G, L469Q, D471E, Q480H, H483C, L491S, L503I, K512R, E516M, L517I, S519N, Q524K, K527E, E529D, A534S, A554S I94M, H361L 

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