Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Yang (2015)
Title Assessing efficacy of different nucleos(t)ide backbones in NNRTI-containing regimens in the Swiss HIV Cohort Study.
Citation J Antimicrob Chemother
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 16
NumPts 16
Subtype B, CRF02_AG, CRF01_AE, A + J

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
17427 17427 TDF, 3TC EFV   K20R, K122E, D123E, I135V, E169ED, E204ED, A272P, K277R, L283I, E297A, I329V, Q334H, F346L  
17610 17610 TDF, 3TC NVP K65R, M184MV K103N, Y181C A98S, K102Q, D123E, E169D, E203EK, R211K  
26346 26346 TDF, 3TC NVP K65R, Y115F, M184V Y181C, H221Y S68G, I178M, V179I, G196E, V245N, D250E, A272P, V276I, L283I, I293V, E297Q, I329L  
26515 26515 TDF, 3TC EFV   D177E, V179I, T200I, R211K, V245M, A272P, I293V, E297Q  
26654 26654 TDF, FTC EFV M41L, T215S  K13KR, E28EK, V60I, A98S, K122E, I135T, G196E, T200A, E204K, R211A, V245M, A272P, T286A, I293V, A304AE  
31745 31745 TDF, 3TC EFV   E6D, K11T, V35T, T39K, K43KE, K122E, D123N, S162C, K173AV, Q174KR, D177E, I178M, V179I, E203D, Q207A, R211X, K238R, V245E, E248D, D250E, A272G, K281KR, T286TA, I293V, E312N, V317A, I329V  
31794 31794 TDF, FTC EFV   E6D, K11T, V35T, T39K, K43KE, K122E, D123N, S162C, K173AV, Q174KR, D177E, I178M, V179I, E203D, Q207A, R211X, K238R, V245E, E248D, D250E, A272G, K281KR, T286TA, I293V, E312N, V317A, I329V  
32135 32135 TDF, FTC EFV   K64R, I135T, S162A, K173A, Q174K, D177E, T200A, Q207E, R211K M164MV 
36115 36115 TDF, 3TC EFV A62V, K65R, M184V, K219N L100I, K103N V35T, T39D, S68N, K122E, D123S, S162A, F171L, R172G, K173Q, Q174K, D177EG, T200A, Q207K, R211K, V245Q, E248D, T286A, E291D, V292I, I293V, L295M  
42155 42155 TDF, FTC EFV D67N K103N V60I, D123E, R211K  
42284 42284 TDF, 3TC EFV A62V, K65R, M184V L100I, K103N, E138A K102Q, K122E, D123A, S162C, T165X, I178L, T200A, E203EK, R211K  
42583 42583 TDF, FTC EFV K65R, D67G, Y115F G190E V35T, V90I, K103R, D123E, D177DN, V179A, I180V, T200A, Q207E  
47778 47778 TDF, 3TC EFV   I135T, S162C, E169D, T200K, A272P, K277R, I293V, K311R, G333E  
52025 52025 TDF, 3TC EFV K70KE, M184V G190EQ E6D, V35T, T39M, I135R, S163T, E169D, K173T, D177E, Q197K, T200E, I202V, Q207KR, R211K, K219X, V245Q, E248D, D250E, S251C, A272P, V276VI, V292I, I293V, E297A, S322E, D324E, A376T, T386I  
52383 52383 TDF, FTC EFV M184V, T215F K103N, G190A K22KR, T27S, V35T, E40D, K46KQ, K101KQ, V118VI, D123E, I135L, S162A, K173T, Q174K, N175NY, D177E, T200A, Q207E, R211K, V245E, E291D, V292I, I293V, P294T, S322T, I329IV, G335D, R356K, M357R, G359S, T369V, A371V, I375A, T377L, K390R, K395R  
57279 57279 TDF, 3TC EFV K65R, V75M, M184V K101E, Y181C, G190S K122E, S162A, D177E, V245K, A272P, K281R, I293V, E297T, Y339W, M357V, K390R  

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