Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Brooks (2016)
Title Treatment failure and drug resistance in HIV-positive patients on tenofovir-based first-line antiretroviral therapy in western Kenya.
Citation J Int AIDS Soc
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 37
NumPts 37
Subtype A, D, C, B, CRF10_CD


Clinical RT Isolates

SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
2003A 2003A TDF, 3TC EFV D67G, K70Q, M184V K101P, K103S, E138Q E6K, K11A, V35T, V60I, K122E, D123S, I135T, I142T, K173S, Q174K, D177E, T200A, Q207A, R211S  
2009A 2009A TDF, 3TC NVP, EFV K65R, M184V A98G, V179F, Y181C, G190A K20R, V35T, K43KR, V60I, K103R, D121Y, K122E, I135T, K173A, Q174K, D177E, T200A, Q207RS, R211NS  
2030A 2030A TDF, 3TC NVP A62AV, K65R, M184V K101E, Y181C, G190A V35T, V60I, K122E, D123S, I135T, K173A, Q174K, D177E, I178M, T200E, E203D, Q207A, R211K  
2033A 2033A TDF, 3TC NVP K65R, Y115F, M184V K101E, Y181C, G190A P4T, V35T, E36A, T39A, K43KE, S48T, S68N, D121H, K122E, T139A, S162C, K173A, Q174R, T200A, I202V, Q207E, R211K E138V 
2041A 2041A TDF, 3TC NVP M184V G190A E6D, K20R, V35T, S48T, K49R, V60I, K122E, D123N, I135T, K166R, E169D, K173A, Q174K, D177E, V179VI, T200A, Q207A, R211S, F214L  
2044A 2044A TDF, 3TC NVP K70E, Y115F, M184V Y181C, H221Y K11S, K32I, V35T, V60I, K122E, D123N, I135R, K173S, D177G, V179I, T200A, I202V, Q207A, L210LS, R211S, L228LR  
2047A 2047A TDF, 3TC NVP K65R, M184I Y181C, M230L V35T, V60I, T69S, D121H, K122E, I135T, K173A, Q174K, D177E, I178M, V179I, Q197E, T200A, E204D, Q207A, R211K  
2050A 2050A TDF, 3TC NVP A62AV, K65KR, K70KE, M184V A98G, Y181C, G190A P14A, V35T, E36EA, T39D, S48T, K64KR, K122E, D123N, S162C, K173T, Q174K, D177E, I178M, V189I, T200A, I202V, E203K, Q207E, R211K, K223KE, L228R  
2052A 2052A TDF, 3TC EFV K65R, K70T, M184I L100I, K103N K11Q, V35T, T39I, K49R, V60I, S68G, V90I, K122E, D123S, I135T, T165I, K173S, Q174K, D177E, T200A, I202V, Q207A, R211S  
2061B 2061B 3TC, D4T, TDF EFV, NVP  K103N V21I, V35T, K49R, V60I, R83K, V118I, D121Y, K122E, R125K, D177E, I178M, T200I, Q207E, R211K  
2065A 2065A TDF, 3TC NVP A62AV, K65R, Y115YF, M184V A98AG, K103KN, Y181C V35T, V60I, K122E, D123S, I135IT, K173S, Q174K, D177E, Q197E, T200A, Q207A, R211S  
2068A 2068A TDF, 3TC NVP K65R, M184MV Y181G, G190A I5IV, K20R, V35T, V60I, S68G, T69S, V90I, K101Q, K122E, D123N, I135T, K173A, Q174R, D177E, V179I, Q207A, R211NS, E224D  
2077A 2077A TDF, 3TC EFV K65R, M184I K103N, M230L, L234I K11H, V35T, V60I, S68G, V90I, K122E, D123G, I135T, K173L, Q174K, D177E, V179I, G196E, T200TA, I202V, Q207A, R211S  
2094A 2094A TDF, 3TC NVP  K103N K11T, V35T, V60I, K102R, D121H, K122E, D123S, I135T, K173S, Q174K, D177E, V179I, T200A, Q207AT, R211S  
2102A 2102A TDF, 3TC EFV K70E, M184V Y181C V35T, K49R, V60I, A98S, K122E, D123S, I135T, D177E, I178M, E203EK, Q207E, R211K, L228LR  
2103A 2103A TDF, 3TC NVP K65R, M184V, K219KE K103N, Y181C E6D, V35T, K49R, V60I, S68SG, I135T, D177E, V179VI, G196E, T200I, Q207G  
2108A 2108A TDF, 3TC NVP   P4T, K20R, V21I, K32I, V35T, T39E, I135R, K173A, D177E, V179I, T200A, I202V, Q207A  
2110A 2110A TDF, 3TC NVP A62V, K65R, D67N, M184V, K219E K101KE, E138AT, Y181C, G190A V35T, D121HY, K122E, I135T, T139A, K173A, Q174K, D177E, V179I, T200TA, Q207T, R211K, E224D  
2116A 2116A TDF, 3TC NVP K65R, M184V K101P, K103N V35T, E40D, K49R, V60I, S68N, K122E, K166R, D177A, V179I, G196E, I202V, Q207E, R211K  
2118A 2118A TDF, 3TC NVP   E6D, V21I, V35T, T39A, E40D, V60I, K64R, K122E, D123G, I135T, D177E, T200R, I202V, Q207G, R211K  
2125A 2125A TDF, 3TC NVP M184I K103N V35T, T39A, V60I, K122E, D123S, I135T, I142V, K173S, Q174K, D177E, G196E, T200A, Q207A, R211S  
2126A 2126A TDF, 3TC NVP   E6P, K11Q, V35T, T39I, V60I, K122E, D123S, I135T, K173AS, Q174K, D177E, I178IV, T200A, I202V, Q207DE, R211S, F214L Y232YC 
2130A 2130A TDF, 3TC EFV A62V, K65R, M184V V106M, Y181C, G190S P4S, V35T, E36A, T39E, S48T, K101Q, K122E, D123N, T165I, K173T, Q174K, D177E, I178M, T200A, I202IV, Q207E  
2131A 2131A TDF, 3TC EFV, NVP K65KR, D67DG, M184MV K101E, Y181YC, G190A E6K, E28K, K32E, V35T, E36Q, E53D, V60I, K122E, I135T, S162H, K173L, Q174K, V179I, T200A, Q207T, R211N  
2134A 2134A TDF, 3TC NVP K65R, M184V Y181C K11T, K20R, V35T, T39K, K43E, G45GE, Y56F, K102Q, D121H, K122E, T139R, K173S, Q174K, D177E, V179I, T200A, I202V, Q207A, R211S P59PA 
2147A 2147A TDF, 3TC NVP K65R, M184I V108I, Y181C K11T, K20R, V21I, V35I, V90I, K101R, K122E, D123N, I135T, A158S, K173L, D177E, V179I, T200S, I202V, Q207A, R211S  
2155A 2155A TDF, 3TC NVP K65R K103N, Y181C E6K, K11Q, V35K, V60I, K122E, D123A, I135T, K173A, Q174K, D177E, T200A, Q207A, R211S  
2156A 2156A TDF, 3TC NVP K65R, Y115F, M184V K103N, Y181C K20KR, K32R, V35T, V60I, K122E, D123S, I135T, T139A, K173A, Q174K, D177E, V179I, T200E, Q207A, R211K, F214L  
2164A 2164A TDF, 3TC NVP K65R, M184V K101E, G190GA V21I, V35T, E36EG, T39A, E40D, K49R, V60I, S68G, I135K, I142L, K173KE, D177E, I178M, V179VI, Y181X, T200A, Q207K, R211K  
2181A 2181A TDF, 3TC NVP M41L, K65KR, L74V, M184V K101E, Y181C, G190A E6EK, E28A, V35T, T39E, V60I, T69S, D121H, K122E, I135T, I142V, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S  
2187A 2187A TDF, 3TC NVP K65R, M184V V108I, Y181C, H221Y K20R, V35T, T39M, V60I, K101Q, K122E, I135T, K173S, Q174K, D177E, I178V, V179I, T200E, Q207A, R211K, F214L  
2194A 2194A TDF, 3TC NVP, EFV K65R, V75M, Y115F, M184V K103N, V108I, Y181C, G190A T27S, V35T, T39M, S48T, V60I, K122E, D123N, I135T, K166R, K173I, Q174K, D177E, V179I, G196E, T200A, Q207A, R211S  
2202A 2202A TDF, 3TC NVP K65R, Y115YF Y181C, H221Y E6D, V35T, T39M, V60I, W88C, K122E, D123S, I135T, K173A, Q174K, D177E, V179I, Q207A, R211S, F214L  
2204A 2204A TDF, 3TC NVP  V106A V35T, E40D, K49R, V60I, K122E, D123E, D177E, T200I, Q207E, R211K  
2208A 2208A TDF, 3TC NVP K65KR, D67DN, K70R, M184V, K219E A98G, G190A K11R, V35T, E36A, V60VI, K122E, D123N, A158S, K173R, D177E, V179I, I195L, T200M, Q207E, R211K  
2213A 2213A TDF, 3TC NVP   V35T, T39M, E40D, K49R, V60I, K122E, D123N, I135T, E169D, Q174K, D177E, I195L, T200A, Q207E, R211K, F214L  
3002B 3002B 3TC, D4T, TDF NVP, EFV   W24C, V35K, T39E, G45R, S48T, G112E, K122E, D123N, I135V, S162G, K173A, D177E, T200A, Q207E, W212C