Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Anstett (2015)
Title Dolutegravir-selected HIV-1 containing the N155H and R263K resistance substitutions does not acquire additional compensatory mutations under drug pressure that lead to higher-level resistance and increased replicative capacity.
Citation J Virol
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
SelectedType Lab
NumIsolates 7
Lab Parent Strain NL43


Lab IN Isolates : Susceptibility Data

IsolateINIMajorDRMsINIMinorDRMsMethodDrugFold Res.
155H157Q263K N155H, R263K E157Q TZM-McGill DTG 14 
      TZM-McGill RAL 26 
155H163R263K N155H, R263K G163R TZM-McGill DTG 13 
      TZM-McGill RAL 13 
155H263K N155H, R263K  TZM-McGill DTG 15 
     TZM-McGill RAL 16 
74M155H263K N155H, R263K  TZM-McGill DTG 9.0 
     TZM-McGill RAL 20 
92Q155H263K E92Q, N155H, R263K  TZM-McGill DTG 17 
     TZM-McGill RAL 50 
97A155H263K N155H, R263K T97A TZM-McGill DTG 17 
      TZM-McGill RAL 28 
WT   TZM-McGill DTG 1.0 
    TZM-McGill RAL 1.0