Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Kouri (2015)
Title CRF19_cpx is an evolutionary fit HIV-1 variant strongly associated with rapid progression to AIDS in Cuba.
Citation EBioMedicine
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 92
NumPts 92
Subtype G, B, D, C, CRF18_cpx, CRF02_AG, F, H

 

Clinical PR Isolates


SubjectIsolatePIsWksPIMajorPIMinorCommonUnusual
AIDS-RP1 AIDS-RP1 None    L10I, K14R, I15V, G16E, E35D, M36I, R41K, K43R, L63P, H69K, I93L  
AIDS-RP10 AIDS-RP10 None    N37D, I72V  
AIDS-RP11 AIDS-RP11 None    G16GE, M36I, N37ND, R41RK, D60E, I62V, L63P, H69Q, I72IV  
AIDS-RP12 AIDS-RP12 None    I13V, K14R, G16E, L19I, K20I, E35D, M36I, R41K, H69K, K70R, I72T, T74S, L89M, T91A  
AIDS-RP13 AIDS-RP13 None    T4S, I13V, N37S, L63A  
AIDS-RP14 AIDS-RP14 None    T12P, I13V, I15IV, M36I, N37S, R41K, R57K, I62V, L63P, V75I, I93L  
AIDS-RP15 AIDS-RP15 None    I13V, I15V, K20I, E35D, M36I, R41K, H69K, V82I, L89M, T91TI  
AIDS-RP16 AIDS-RP16 None    N37S, R41K, H69K, T74S, V77I, L89M, I93L  
AIDS-RP17 AIDS-RP17 None    I13V, G16E, K20I, E35D, M36I, R41K, I64IM, H69K, K70R, L89M  
AIDS-RP18 AIDS-RP18 None    L10I, I13V, K14R, K20I, E35ED, M36I, L63LP, C67DN, H69K, V82I, L89M, I93L, F99FL  
AIDS-RP19 AIDS-RP19 None    T12S, L19I, K20R, M36I, R41K, L63M, H69K, L89M, I93L  
AIDS-RP2 AIDS-RP2 None    I15V, E35D, M36I, R41K, K43R, I62IV, L63PS, H69K, K70Q, A71T, I93L  
AIDS-RP20 AIDS-RP20 None    I13V, K14R, G16E, K20I, E35D, M36I, R41K, I64M, H69K, K70R, L89M  
AIDS-RP21 AIDS-RP21 None    I13V, K14R, K20I, M36I, R41K, I64M, H69K, K70R, V82I, L89M  
AIDS-RP22 AIDS-RP22 None    L10I, I13V, I15V, E35Q, M36I, N37D, I62V, L63T, H69K, A71T, I72IT, I93L  
AIDS-RP23 AIDS-RP23 None    I13V, K14R, G16E, K20I, E35D, M36I, R41K, I64M, H69K, K70R, L89M  
AIDS-RP24 AIDS-RP24 None    I13V, N37S, R41K, L63P, I64L, I72V, V77I, I93L  
AIDS-RP25 AIDS-RP25 None    L5F, T12A, I13V, G16E, L63A  
AIDS-RP26 AIDS-RP26 None    L10I, I13V, K14R, I15V, K20I, E21D, E35D, M36I, R41K, C67N, H69K, V82I, L89M  
AIDS-RP27 AIDS-RP27 None   N88ND I13V, K14R, I15V, K20I, E35D, M36I, P39PS, R41K, I64M, H69K, L89M  
AIDS-RP28 AIDS-RP28 None    I13V, L19I, E35D, N37S, R41K, L63P, H69Q, A71T  
AIDS-RP29 AIDS-RP29 None    E35D, M36I, N37E, R41K, K43KR, D60E, Q61E, L63P, H69Q, I93L  
AIDS-RP3 AIDS-RP3 None    I13V, I15V, K20I, M36I, R41K, I64M, H69K, L89M  
AIDS-RP30 AIDS-RP30 None    E35D, N37NS, P39S, R41RK, D60E, L63P, V77I  
AIDS-RP31 AIDS-RP31 None    E35D, R41K, L63C, H69K, L89M  
AIDS-RP32 AIDS-RP32 None    I13V, K14R, K20I, E35D, M36I, R41K, H69K, V82I, L89M  
AIDS-RP33 AIDS-RP33 None    T12S, E35D, R41K, R57K, L63P, I93L F99FV 
AIDS-RP34 AIDS-RP34 None    I13V, E35D, N37S, R41K, L63P, H69Y  
AIDS-RP35 AIDS-RP35 None    L10I, I13V, K20I, E35D, M36I, D60E, H69K, L89M  
AIDS-RP36 AIDS-RP36 None    N37S, R41K, L63P, H69K, L89M, I93L  
AIDS-RP37 AIDS-RP37 None    L10I, I13V, L19I, K20I, E35D, M36I, D60E, H69K, L89M  
AIDS-RP38 AIDS-RP38 None    L10V, I13V, K14R, G16E, E35D, N37T, R41K, L63H, I64V  
AIDS-RP39 AIDS-RP39 None    K14R, M36I, N37D, R41K, K43R, L63P, H69Q  
AIDS-RP4 AIDS-RP4 None    L10I, T12A, I13V, K14R, G16E, K20I, E35D, M36I, R41K, L63S, H69K, K70R, V82I, L89M  
AIDS-RP40 AIDS-RP40 None    L10I, I13V, K14R, K20I, M36I, N37ND, R41K, R57K, H69K, V82I, L89M Q7L 
AIDS-RP41 AIDS-RP41 None    I13V, K14R, K20I, E35N, M36I, R41K, H69K, V82I, L89M  
AIDS-RP42 AIDS-RP42 None    L10N, K14R, L19I, N37S, R41K, C67D, H69K, L89M, I93L  
AIDS-RP43 AIDS-RP43 None    L10V, I13V, G16E, E35D, M36I, P39T, R41K, D60E, I62V, L63T, H69K, V77I, L89I  
AIDS-RP44 AIDS-RP44 None    T4I, V11I, I13V, K14R, K20I, E35D, M36I, R41K, H69K, V82I, L89M  
AIDS-RP45 AIDS-RP45 None    L10I, I13V, K20I, E35D, M36I, R41K, K43R, C67CY, H69K, V82I, L89M  
AIDS-RP46 AIDS-RP46 None  M46I  G16E, M36I, R41K, D60E, I62V, L63P, H69R, I93L  
AIDS-RP47 AIDS-RP47 None    I13V, K14R, K20I, E35D, M36I, R41K, H69K, T74S, L89M  
AIDS-RP48 AIDS-RP48 None    I15V, L19I, M36I, N37S, R41K, H69K, L89M, I93L  
AIDS-RP49 AIDS-RP49 None    I13V, K14R, G17E, K20I, E35N, M36I, R41K, L63P, H69K, K70R, L89M  
AIDS-RP5 AIDS-RP5 None    L10I, T12A, I13V, K14R, G16E, K20I, E35D, M36I, R41K, L63S, H69K, K70R, V82I, L89M  
AIDS-RP50 AIDS-RP50 None    I13A, K14R, K20I, M36I, N37D, R41K, Q61H, H69K, K70KR, L89M R87P, T96TI, L97Y 
AIDS-RP51 AIDS-RP51 None    I13V, K20I, E35D, M36I, R41K, D60E, Q61QE, L63LP, H69K, L89M  
AIDS-RP52 AIDS-RP52 None    T12P, K14R, M36I, N37D, L63A, I72T, I93L  
AIDS-RP6 AIDS-RP6 None    L10I, I13V, K14R, K20I, E35D, M36I, D60E, L63LP, C67N, H69K, L89M  
AIDS-RP7 AIDS-RP7 None    L10I, I13V, M36I, R41K, L63P, H69Q  
AIDS-RP8 AIDS-RP8 None    I13V, K14R, K20I, E35D, M36I, R41K, H69K, V82I, L89M  
AIDS-RP9 AIDS-RP9 None   K43KT N37S, I64V  
C_AIDS1 C_AIDS1 None    E35D, N37S, R41K, D60E, L63P  
C_AIDS10 C_AIDS10 None    Q2H, L10I, I13V, K14R, K20I, E35D, M36I, R41K, D60E, Q61E, H69K, V82I, L89M  
C_AIDS11 C_AIDS11 None    I13V, K14R, K20I, E35D, M36I, R41K, H69K, V82I, L89M  
C_AIDS13 C_AIDS13 None    P9T, I13V, K14R, P39PS, R41K, L63P, I72IV, V77I, I93IL  
C_AIDS14 C_AIDS14 None    I13V, K20I, E35D, M36I, N37S, R41K, R57K, H69K, K70R, V82I, L89M  
C_AIDS15 C_AIDS15 None    P39T, L63T, A71V, I72T, V77I, I93L  
C_AIDS16 C_AIDS16 None    Q2H, I13V, K14R, G16E, K20I, E35D, M36I, R41K, H69K, K70KR, L89M, T91A  
C_AIDS17 C_AIDS17 None    I15V, L19I, M36I, N37S, R41K, L63AS, H69K, L89LM, I93L G49R 
C_AIDS18 C_AIDS18 None    N37S, R41K, L63P, H69R, V77I, L89M, I93L  
C_AIDS19 C_AIDS19 None    L10I, I13V, G16E, K20KR, E35D, M36I, R57K, Q61E, L63S, H69Q, K70R, L89M  
C_AIDS2 C_AIDS2 None    I13V, E35D, N37S, R57RK, L63P, V77VI  
C_AIDS20 C_AIDS20 None    I13V, K14R, K20I, M36I, R41K, C67H, H69K, V82I, L89M  
C_AIDS21 C_AIDS21 None    K14KR, M36I, N37S, I62V, L63T, H69K, A71T, I93L  
C_AIDS22 C_AIDS22 None    I13V, K14R, G17E, K20I, E35D, M36I, R41K, H69K, L89M  
C_AIDS3 C_AIDS3 None    L10I, T12K, I13V, K20I, M36I, N37D, R41K, C67Y, H69K, L89M G17V 
C_AIDS4 C_AIDS4 None    T12S, I13V, G16E, L19I, K20I, E35D, M36I, R41K, I62IV, H69K, K70R, V77VI, L89M  
C_AIDS5 C_AIDS5 None    N37NS, R57K, I62V, L63S, I64L, K70T, A71V, I72T, I93L  
C_AIDS6 C_AIDS6 None    K14KR, G16E, P39S, D60E, L63P, V77I  
C_AIDS7 C_AIDS7 None    K20R, E35D, M36I, N37D, R41K, K43R, Q61N, L63P, I64L, H69Q  
C_AIDS8 C_AIDS8 None    T12A, E35D, Q61E, L63P, I93L  
C_AIDS9 C_AIDS9 None    I13V, I15V, G16E, I62IV, L63S, I64V, V77I  
N_AIDS1 N_AIDS1 None    I15V, L19T, K20M, E35D, M36I, K43R, I62IV, L63P, I93L  
N_AIDS10 N_AIDS10 None    L10V, I13V, E35D, N37T, R41K, L63HQ, I64V  
N_AIDS12 N_AIDS12 None    I13V, I15V, N37S, P39S, I62V, L63P, V77I  
N_AIDS13 N_AIDS13 None    I13V, K14R, G17E, K20I, E35N, M36I, R41K, H69K, L89M  
N_AIDS14 N_AIDS14 None    I13V, M36I, N37S, I62V, L63A, L89M  
N_AIDS15 N_AIDS15 None    I13V, K14R, G16GR, K20I, E35D, M36I, R41K, C67Y, H69K, K70R, V82I, L89M  
N_AIDS16 N_AIDS16 None    I13V, K14R, G17E, K20I, E35D, M36I, R41K, H69K, V82I, L89M  
N_AIDS17 N_AIDS17 None    T4S, I13V, N37S, P39Q, L63P  
N_AIDS18 N_AIDS18 None    I13V, K14R, E35D, N37S, R41K, L63P  
N_AIDS19 N_AIDS19 None    I13V, L63P  
N_AIDS2 N_AIDS2 None    I13V, I15IV, K20I, E35D, M36I, R41K, H69K, V82I, L89M  
N_AIDS21 N_AIDS21 None    L10I, I13V, K14R, K20I, M36I, C67DE, H69K, L89M  
N_AIDS3 N_AIDS3 None    I13V, K14R, K20I, E35D, M36I, R41K, H69K, V82I, L89M  
N_AIDS4 N_AIDS4 None    I15V, L19I, E35D, N37Q, R41K, K45R, L63P, E65D, I93L K70S 
N_AIDS5 N_AIDS5 None    L10LI, I13V, K14R, I15IV, K20I, E35D, M36I, R41K, I64V, C67X, V77VI  
N_AIDS6 N_AIDS6 None    I13V, K14R, G16E, K20I, E35D, M36I, R41K, K45R, H69K, V77VI, L89M  
N_AIDS7 N_AIDS7 None    I13V, K20I, E35D, M36I, R41K, C67Y, H69K, V82I, L89M  
N_AIDS8 N_AIDS8 None    I13V, K14R, G16E, K20I, E35D, M36I, D60E, L63P, H69K, L89M, I93L  
N_AIDS9 N_AIDS9 None    L10V, I13V, G16GE, E35D, N37T, R41RK, L63HQ, I64V  

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