Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Grossmann (2015)
Title Subtype-independent near full-length HIV-1 genome sequencing and assembly to be used in large molecular epidemiological studies and clinical management.
Citation J Int AIDS Soc
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 24
NumPts 24
Subtype C, B, CRF02_AG, CRF01_AE

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
SE600001 SE600001 None None   R83RK, K102Q, S162C, N175H, G196E, T200A, Q207K, R211A, T286A, T296S, S322T, G335C, G359S, A371V, K390R, E432D, K451R, R461K, V467I, T470P, Q480H, H483Y, L491S, K558R  
SE600012 SE600012 None None   E6D, R83K, D177E, I178M, G196E, Q197H, T200A, Q207K, R211A, P247Q, E248K, A272P, T286A, V317A, Q334L, R356K, G359S, K451R, R461K, V466A, L469I, Q480H, S519N  
SE600023 SE600023 None None T215S  R83K, K122E, D123G, K173Q, Q174K, I178M, T200I, Q207K, R211Q, E224G, L234P, V245K, E248R, A272P, L283F, T286P, I293V, K311R, S322T, G333E, Q334L, K385R, K390R, A400I, V417I, V435E, D460N, A554T  
SE600034 SE600034 None None   K20R, V90I, K101Q, V118I, I135R, T165I, Q174H, D177E, V179I, T200A, R211Q, F214L, A272P, K277R, T286P, A288P, D324E, I329L, G333E, M357T, A360T, A376T, I382T, T386I, A400T, T403R, R461K, S468T, I556V, K558R K323N 
SE600035 SE600035 None None   E6D, R83K, K104N, T165I, D177E, T200A, I202V, Q207K, R211A, V276T, K277R, Q278E, T286A, Q334L, F346G, R356K, G359S, K366R, K451R, R461K, Q480H, K512R, E516A  
SE600046 SE600046 None None   V35T, V60I, R83K, K102R, I135T, I178M, G196E, T200A, Q207K, R211A, A272S, A288S, T296S, V317A, S322T, P345Q, A355T, M357S, K366R, T377Q, K390R, E404D, D460N, V466I, H483Y, K512R, S519N, V548I, A554N  
SE600057 SE600057 None None   V35I, D86E, K104KN, K122Q, T200I, R211K, V245M, K277R, R284K, T286A, I293V, E297K, I326V, M357I, T377Q, K390R, E399D, A400L, T403M, E449D, T470S, H483N  
SE600063 SE600063 None None   K20E, E28D, E36Q, K49R, R83K, T200A, E204K, V261G, A272S, T286A, K311R, I329V, Q334E, T369A, K390R, R461K, L517I, K530R, A554T  
SE600108 SE600108 None None  N348I V35T, E36A, T39E, S48T, K122E, D123S, K173A, Q174K, D177E, T200A, Q207A, R211K, P243T, V245Q, A272P, T286A, E291D, V292I, P294T, I329V, G333D, Q334N, R356K, G359T, T377M, T386I, K390R, A400T, E404D, K431T, I434L, V435G, A437V, E449D, L452K, V466I, T470E, D471E, T477A, H483Q, L491S, S519N, K530R, A534S, A554S  
SE600119 SE600119 None None   V8I, V35T, E36A, T39D, S48T, K122E, K173A, D177E, T200A, Q207N, R211K, V245Q, P247Q, E248T, D250N, A272P, L279M, T286A, E291D, V292I, I293V, I329L, Q334N, G335D, G359T, T377Q, K390R, A400T, E404D, E413D, I434M, A437V, E449D, R461K, V466I, V467I, D471E, T477A, H483Q, S519N, A534S, A554K  
SE600122 SE600122 None None   T27S, V35T, E36A, T39E, S48T, K122E, D123S, S162C, K166R, K173A, D177E, G196R, T200A, I202V, Q207E, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, V292I, I293V, V317A, I329V, Q334E, G335D, R356K, G359T, T386V, K390R, E399D, A400T, E404D, K431Q, A437V, L452I, V466I, D471E, T477A, H483Q, L491S, S519N, A534S, V548I, A554K  
SE600210 SE600210 None None   V35T, E36A, T39E, A98S, K122E, D123S, I135T, A158S, K173A, D177E, I195V, G196R, T200A, Q207A, R211K, V245Q, E248D, A272P, T286A, E291D, V292I, Q334N, G335D, R356K, M357T, G359T, T377L, T386M, K390R, A400T, E404D, E413D, I434M, A437V, L452I, V466I, T470N, D471E, T477A, H483Q, L491S, D511N, L517I, S519N, I526V, K530R, A534S, A554K  
SE600213 SE600213 None None   V35T, T39E, A98S, K122E, D123N, K173A, Q174K, D177E, T200A, I202V, Q207E, W212L, F214I, P236S, P243L, V245Q, A272P, K277R, G285E, T286A, E291D, V292I, I293V, P294A, L310I, Q334D, G335D, R356K, M357R, G359T, T377L, S379G, K390R, A400T, E404D, V435A, L452I, V466I, D471E, H483Q, L491S, L517I, S519N, K527Q, K530R, A534S, A554S T215H, H235S 
SE600311 SE600311 NRTI NNRTI   T27S, V35T, E36A, T39E, V90I, A98S, K122E, D123S, I135T, Q145C, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, A272P, T286A, E291D, V292I, P294T, Q334H, G335D, R356K, M357R, G359T, T377Q, K390R, E404D, V435A, N447S, L452I, V467I, D471E, H483Q, L491S, L517I, S519N, K527Q, A534S, A554N, V559I  
SE600314 SE600314 None None  E138A V35T, T39TK, S48T, V60I, V118I, K122E, I135T, E169Q, K173AT, Q174KN, T200A, Q207E, R211K, F214L, V245Q, E248D, A272P, K275R, Q278H, T286A, E291D, V292I, I293V, P294T, L301F, S322E, D324E, I329V, Q334H, G335D, G359T, T377Q, S379A, K390R, E396D, T397I, A400T, T403A, E404D, V435A, A437V, V458I, R461K, D471E, T477A, H483Q, L491S, S519N, K527N, E529G, K530R, A534S, A554S  
SE600412 SE600412 None None   V35T, E36A, T39E, K122E, D123S, I135T, K173A, D177E, T200A, E204K, Q207E, R211K, F214L, V245Q, A272P, K275R, V276I, K277R, Q278E, T286A, E291D, V292I, I293V, P294T, V317A, Q334P, G335S, K347R, R356K, M357G, R358G, G359T, T369V, K374R, A376P, T377M, I382L, L391I, E399G, A400T, W401C, T403R, E404D, W406C, A408V, W410G, E415D, N418S, P421L, L422I, L425I, Q428K, V435A, A437V, D443E, A446D, N447S, L452M, K454R, V466I, V467F, S468F, T470R, D471E, T473P, K476R, T477I, L479F, H483Q, L484I, L491S, N494S, Q507H, K512Q, L517I, Q520K, E523K, A534S, V536I, A554N K366E, Q373L, I375K, P387S, P433S, I434R, V458R, T459V, A485N, D498E, S499K, I505F, I506S, V518D, K528S, I542F 
SE600415 SE600415 None None  N348I K32R, V35T, T39K, E40D, A98S, K122E, D123S, S163N, P170S, K173T, D177E, G190R, T200A, Q207E, V245Q, A272P, K275R, V276I, T286A, E291D, V292I, I293V, P294T, Y319F, S322A, Q334H, G335D, R356K, M357R, G359T, A371V, I375A, T377M, K390R, A400T, E404D, V435A, A437V, L452I, S468P, H483Q, L491S, L517I, S519N, K527Q, K530R, A534S, A554N  
SE600516 SE600516 None None   V35T, E36A, T39A, K43Q, A98S, K122E, D123G, D177E, Q197E, Q207A, R211K, V245H, K249Q, A272P, T286A, E291D, V292I, I293V, K311R, Q334H, G335D, R356K, M357R, G359T, A376S, T377L, S379G, T386I, K390R, A400T, E404D, E413D, V435M, L452G, V458I, T470N, D471E, T477A, H483Q, L491S, L517I, S519N, K530R, A534S, A554S  
SE601017 SE601017 None None   E6D, K20R, V35T, T39K, K43E, V60I, S68G, K122E, D123N, I135T, T165I, K173I, Q174K, D177E, I178L, T200I, Q207A, R211S, F214L, K238R, V245E, A272P, K281R, T286A, E291D, V292I, I293V, E312T, I329V, G335D, M357K, G359S, K366R, A371V, I382T, K390R, K395R, A400T, E432D, N447S, D471E, Q480H, H483Q, L491S, L517V, S519N, Q524E, E529D, A534S, A554T  
SE601018 SE601018 None None  E138A E6D, V35T, T39K, K43E, K122E, D123S, I135V, S162C, K173I, Q174K, D177E, V179I, T200A, Q207A, R211K, K238R, V245E, T286A, E291D, I293V, E312N, I326V, G335D, R356K, M357K, R358G, G359S, E370A, A371L, A376V, V381I, K395R, A400T, T403M, V435I, L452I, R461K, D471E, Q480H, H483Y, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
SE601021 SE601021 None None   E6D, K11T, V35T, T39K, K43E, R83K, K122E, D123N, I142V, K173I, Q174K, Q207A, R211S, K238R, V245E, V276I, T286A, E291D, V292I, I293V, E312T, I326T, I329V, G335D, M357K, G359S, K366R, A371V, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, Q509H, D511A, K512R, L517V, I522M, Q524G, I526L, A534S, A554S  
SE602019 SE602019 None None   V35T, V60I, I135V, S162A, K173R, Q174K, D177E, T200A, Q207E, R211K, V245Q, K281R, T286A, E291D, V292I, I293V, S322T, I326V, G335D, R356K, M357K, G359S, T369V, A371V, I375V, A376S, T377M, K390R, E399D, T403M, E432D, R461K, V466A, D471E, Q480H, H483Y, L491S, K512R, S519N, Q524K, K527E, E529D, A534S, A554N  
SE602020 SE602020 NRTI NNRTI M184V V106A, F227L P4S, V35T, T39A, E53D, S68G, A98S, D123E, I135V, S162A, K173A, Q174K, D177E, T200A, Q207E, R211K, F214L, D237N, V245Q, E248D, A272P, V292I, I293V, P294T, S322T, G335D, R356K, M357K, G359S, K366R, A371V, I375V, K390R, A400T, T403M, E432D, R448K, V467I, D471E, Q480H, L491S, K512R, S519N, Q524K, K527Q, E529D, A534S, A554N  
SE602024 SE602024 None None   V35T, T39A, S68G, I135V, S162A, K173I, Q174K, D177G, T200A, Q207E, V245Q, E248D, A272P, K277R, L279M, T286A, E291D, V292I, I293V, P294T, R307K, S322T, I326V, G335D, R356K, M357R, G359S, A371V, T377Q, K390R, T403M, E432D, V435R, V466I, T470D, D471G, Q480H, H483Y, L491S, E514D, L517I, S519N, Q524K, K527E, E529D, A554S  

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