Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Hassan (2014)
Title HIV-1 virologic failure and acquired drug resistance among first-line antiretroviral experienced adults at a rural HIV clinic in coastal Kenya: a cross-sectional study.
Citation AIDS Res Ther
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 55
NumPts 55
Subtype A, D, C, B

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
RS09000753 RS09_753 3TC, D4T NVP   K11Q, V35T, E36D, E40D, K122E, D123N, I135T, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, V245E, D250E, K281R, T286A, I293V, P294T  
RS09000761 RS09_761 AZT, 3TC NVP   E6D, V35T, T39G, K49R, N175H, T200A, Q207E, R211K, V245K, A272P, K277R, K281R, T286A, A288T, E291D, V292VI, I293V, E297K, A304E, E312D  
RS09000774 RS09_774 AZT, 3TC NVP   I31IV, V35T, V60I, D121H, K122E, I142V, D177E, T200K, E204Q, Q207D, R211K, D250E, A272S, L282C, L283I, T286A, I293V  
RS09000776 RS09_776 3TC, D4T NVP M184V K103N, M230ML V8I, V35T, S48T, V60I, T69TN, D121C, K122E, T139A, Q207E, R211K, D250E, A272S, K277R, L282C, L283I, I293V  
RS09000778 RS09_778 3TC, D4T NVP   P4H, V35T, S48T, V60I, D121H, K122E, I135T, S162C, K173S, Q174K, T200TA, Q207A, R211S, V245I, D250E, T286A, E291ED, I293V, P294T, E300Q, E312D  
RS09000779 RS09_779 3TC, D4T NVP M184V K103N, V106VI, M230ML E28EK, V35T, V60I, V118I, D121H, K122E, I135T, I142V, K173L, Q174K, D177E, T200A, Q207A, R211S, E248D, D250E, A272P, K277R, T286A, E291D, V292I, I293V, P294T  
RS09000784 RS09_784 3TC, D4T NVP M184V, K219KE V108VI, Y181YC, G190GA V35T, K49KR, V60I, K122E, D123N, I135T, T139TI, K173S, Q174K, D177E, V179I, Q207A, R211S, V245Q, E248D, D250E, S251N, A272P, T286A, E291D, V292I, I293V, E312D  
RS09000786 RS09_786 3TC, D4T NVP   V21I, V35T, T39K, K43E, D121H, K122E, A158S, T165I, K173S, D177E, V179I, T200A, I202V, Q207A, V245Q, D250E, T286A, V292I, I293V, P294T, E312D E40T 
RS09000788 RS09_788 AZT, 3TC NVP   K11KT, V35T, V60I, K122E, I135T, K173T, Q174K, D177E, V179I, T200A, I202V, Q207D, V245K, D250E, S251H, K281R, T286A, E291D, V292I, I293V, E312N  
RS09000791 RS09_791 AZT, 3TC NVP   V35T, V60I, K122E, I135T, D177E, I178M, Q207A, R211N, V245Q, D250E, A272P, K277R, L282C, I293V, P294S, E297R, A304E  
RS09000793 RS09_793 AZT, 3TC NVP   K11T, K20R, V21I, V35T, T39E, K122E, D123N, K173S, D177E, V179I, T200A, I202V, E203K, Q207A, R211K, V245Q, E248S, T286A, E291D, I293V, P294T, E312D  
RS09000794 RS09_794 AZT, 3TC NVP, EFV   K32R, V35T, E36A, T39E, K122E, D123S, K173T, D177E, T200A, Q207E, R211K, V245Q, A272P, K275R, Q278N, L283LI, T286A, E291D, V292I, I293V, P294T, L295M, P313T  
RS09000800 RS09_800 3TC, D4T NVP  K103N K11E, V35T, V60I, D121H, K122E, D123S, I135T, K173A, Q174K, D177E, V179I, T200A, Q207A, R211S, V245Q, E248N, T286A, E291D, I293V, P294T, E312D  
RS09000807 RS09_807 3TC, D4T EFV   K20R, V21I, V35T, T39R, K43KE, G45GE, K122E, D123GS, I142IT, K166R, K173A, Q174R, D177E, I178L, V179T, T200TA, Q207A, R211K, F214L, D250E, A272P, K277R, T286A, A288AT, E291D, V292I, I293V, E312D, V317A  
RS09000809 RS09_809 AZT, 3TC NVP M184V, T215Y Y181C, H221Y K11T, I31L, V35K, T39E, K49KR, K122E, D123S, I135T, K173S, Q174K, D177E, V179I, Q207A, R211S, F214L, V245E, R284K, E291D, V292I, I293V, P294T, E312D  
RS09000813 RS09_813 AZT, 3TC NVP   P4S, I5V, K11A, K20R, V21I, V35T, T39A, D123N, K173S, D177E, V179I, I202V, Q207A, R211S, V245Q, D250E, T286A, E291D, V292I, I293V, E312D  
RS09000815 RS09_815 AZT, 3TC NVP D67DG K103N, G190A K22R, E28A, V35T, K122E, D123S, S162SN, K173S, Q174K, D177E, T200A, E203D, Q207A, R211K, V245K, A272P, T286A, E291D, V292I  
RS09000819 RS09_819 3TC, D4T NVP M184V K103N, K238T K11T, V21I, V35T, T39N, V60I, K122E, D123N, N147NK, E169EK, R172RK, K173A, Q174K, D177EK, E194EK, R199RK, T200A, I202V, R206RK, Q207A, R211S, V245Q, E248DN, V261VG, Y271F, A272P, K275Q, R284RK, T286A, E291DN, I293V, P294V, E300EK, E302EK, E305EK, E312DN  
RS09000825 RS09_825 3TC, D4T NVP M184V K103N V35T, K49R, V60I, V90I, D121Y, K122E, I135M, S162N, K173L, Q174K, T200A, Q207A, R211S, V245Q, D250E, A272S, T286A, E291D, I293V, E297Q, E312D  
RS09000831 RS09_831 3TC, D4T NVP M184V G190A P4H, K11T, K20R, V21I, V35T, V60I, D123N, I135IMT, K173S, Q174K, D177E, I178L, V179I, T200A, Q207A, R211S, V245Q, E291D, I293V, P294A, E312D  
RS09000833 RS09_833 3TC, D4T NVP M184V K103N, K238T V35T, K49R, V60I, I135T, D177E, I178V, T200I, Q207E, R211K, L228LR, V245E, D250E, A272P, V276I, Q278H, K281R, L282C, L283I, T286A, V292I, I293V  
RS09000840 RS09_840 3TC, D4T NVP   V35T, E36A, T39E, K43R, K122A, D123S, K173T, Q174K, D177E, T200A, Q207E, P243S, V245Q, S251SN, A272P, K277R, T286A, E291D, V292I, I293V  
RS09000841 RS09_841 AZT, 3TC NVP M184MV Y188L K20R, K32R, V35K, T39A, V60I, D121H, K122E, I135T, I142V, T165I, K173E, Q174K, D177E, V179I, T200A, Q207AT, R211S, V245EK, D250E, T286A, E291D, V292VI, I293V, P294T, E297R, A304E, E312D  
RS09000843 RS09_843 3TC, D4T NVP   E6Q, K20R, V21I, V35T, T39A, V60I, K102KQ, D121DH, K122E, I135T, D177G, T200A, Q207EG, R211K, V245T, K281R, T286A, E291D, V292I, I293V, E297K, A304E, E312D  
RS11000368 RS11_368 AZT, 3TC NVP   E28A, V35T, V60I, K122E, D123GS, R143RK, K173L, Q174K, D177E, T200A, Q207X, R211EK, V245K, A272P, K277R, T286A, E291D, V317VA  
RS11000370 RS11_370 AZT, 3TC NVP  G190A E6T, V35T, T39A, V60I, V118I, K122E, I135T, K173A, Q174K, D177E, V179I, T200A, E204D, Q207A, R211S, F214L, V245Q, D250E, T286A, E291D, V292I, I293V, E312D  
RS11000374 RS11_374 AZT, 3TC NVP M184V V106A V21I, V35T, T39E, K49KR, K122E, D123G, Q174K, D177E, I178L, Q207A, R211K, V245Q, A272P, K281R, T286A, A288T, E291D, V292I, I293V, E297K, A304E, E312D  
RS11000379 RS11_379 3TC, D4T, AZT NVP   V35T, T39X, E40ED, K64KR, D121H, K122E, I135T, D177E, V179I, Q207E, R211K, V245K, V261VI, T286A, E291D, V292VI, E297K, A304E, E312D  
RS11000383 RS11_383 3TC, D4T NVP   V35T, K49R, V60I, D121H, K122E, I135T, Q145C, D177E, I178M, T200IM, Q207G, R211K, I244V, V245T, D250E, A272P, K277R, L282C, L283I, I293V, P294T  
RS11000385 RS11_385 AZT, 3TC EFV M184V K103N, E138A V35T, T39L, V60I, K102Q, K122E, I135T, K173S, Q174K, V179I, T200A, Q207A, R211S, Y232H, V245E, E248D, D250E, T286A, E291D, I293V, P294T, V317A  
RS11000394 RS11_394 AZT, 3TC NVP   K32Q, V35T, E40D, K49R, V60I, K122E, D123N, I135T, W153WR, E169D, K173L, Q174K, D177E, V179I, T200A, Q207A, R211K, V245R, A272P, T286A, I293V  
RS11000400 RS11_400 3TC, D4T, AZT NVP   K11T, K20R, V21I, V35X, T39TIM, D121H, K122E, D123S, I135T, I142L, K173S, D177E, V179I, T200K, I202V, Q207A, R211S, V245Q, E248ED, T286A, E291D, I293V, P294T, E312D  
RS11000410 RS11_410 AZT, 3TC NVP   K11T, V35T, A98AS, D121H, K122E, I135T, I142T, K173E, D177E, I178M, Q207E, R211K, P243A, V245K, K275Q, K281R, T286TA, E291D, V292I, I293V, P294T, E297R, A304E, E312N  
RS11000411 RS11_411 AZT, 3TC NVP M41L, D67N, K70R, M184V, T215Y, K219Q Y181IV, H221Y P4S, E6D, K11S, V21I, K32I, V35T, T39K, V60I, D123N, V148VG, S162SN, T165TK, K173S, Q174K, D177E, V179I, T200A, I202V, Q207A, R211K, P243S, V245K, R284RK, T286A, E291D, V292I, I293V  
RS11000415 RS11_415 3TC, D4T NVP M184V Y181C T7A, V35T, T39M, V60I, D123S, I135T, K173T, Q174K, D177E, T200A, I202V, Q207A, R211N, T286A, V292I, I293V, P294T, E312N  
RS11000424 RS11_424 AZT, 3TC EFV, NVP   I5V, V35T, T39N, V60I, I135T, K173S, Q174K, D177E, G196E, T200A, Q207A, R211K, F214L, V245N, D250E, A272P, T286A, E291D, V292I, I293V, L295M, E312EK  
RS11000425 RS11_425 AZT, 3TC NVP   E6K, K11Q, K32R, V35T, T39A, S48T, V111I, K122E, D123S, K173A, Q174K, D177E, I202V, Q207A, R211K, F214L, V245Q, A272P, K277R, T286A, E291D, V292I, I293V  
RS11000426 RS11_426 3TC, D4T, AZT NVP  K101E, G190A E28K, K32Q, V35T, K49R, V60I, K122E, D123N, I135T, S162C, K173S, Q174K, D177G, V179I, T200A, E203EQ, Q207A, R211S, D237DN, V245T, D250E, A272P, T286A, E291D, V292I, I293V, P294T  
RS11000437 RS11_437 3TC, D4T, AZT NVP M184V Y181C K11T, V21I, V35T, T39Q, V60I, K122E, D123S, I135V, T165M, K173S, Q174T, D177E, V179I, T200A, I202V, Q207A, R211K, V245Q, E248D, T286A, E291D, V292I, I293V, E312D  
RS11000440 RS11_440 AZT, 3TC NVP   P4T, I5V, V35T, T39KR, V118I, D121H, K122E, I135T, T165I, D177E, I178L, Q207K, R211A, F214L, V245K, A272P, T286A, E291D, V292I, I293V, E297K, A304E, E312D  
RS11000442 RS11_442 AZT, 3TC NVP M184V Y181C I5V, V35T, V60I, D121Y, K122E, D123E, I135T, K173S, Q174K, D177E, V179I, G196E, T200V, Q207A, K238R, V245T, D250E, A272P, E291D, V292I, I293V, E312D, V317G  
RS11000443 RS11_443 3TC, D4T NVP M184V K103N P4T, V35T, T39N, D121Y, K122E, S162C, D177E, I178L, Q207E, R211K, V245T, E248D, D250E, A272P, K281R, T286A, V292I, I293V, E297K, A304E, E312D  
RS11000445 RS11_445 AZT, 3TC NVP M184V V106A K11T, K20R, V21I, V35T, T39K, E40D, V60I, K122E, D123N, I135T, S163T, K173S, D177E, V179I, Q197K, T200E, I202V, E203Q, Q207D, R211K, F214L, V245Q, E248D, T286A, E291D, I293V, P294T, E312N  
RS11000450 RS11_450 AZT, 3TC NVP  K103N P4H, L12I, V35T, T39M, V60I, L109I, K122E, D123S, I135T, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, D250E, T286A, I293V, V317A  
RS11000460 RS11_460 AZT, 3TC NVP M184V K103S, E138A, G190A V35T, V60I, S68G, V90VI, K122E, D123N, K173L, Q174K, I178L, V179I, Q207A, R211S, V245X, D250DE, A272P, T286A, E291D, V292I, I293V, K311R, E312D  
RS11000464 RS11_464 AZT, 3TC NVP L74V, M184V K103N, Y181C, H221Y K11E, V35T, V60I, V90VI, D121H, K122E, D123S, I135T, T165I, K173S, Q174K, G196E, T200A, Q207A, R211S, T286V, E291D, I293V, P294T  
RS11000466 RS11_466 3TC, D4T NVP M184V V106A, F227L E6K, K32R, V35T, V60I, K122E, T131TP, D177E, I178L, T200I, I202IV, Q207E, R211K, T216TP, V245K, D250E, A272P, K277R, L282C, T286A, A288T, I293V, E297A  
RS11000482 RS11_482 AZT, 3TC NVP M184V Y181C K11T, V21I, V35IMT, T39R, K43E, I47IL, K49KR, K122E, D123S, S162N, K173S, Q174K, D177E, V179I, I202V, Q207A, V245Q, E248D, A272P, Q278H, K281R, T286A, E291D, V292I, I293V H96HP 
RS11000492 RS11_492 AZT, 3TC NVP M184V K103KN, Y318YF V35T, E40D, K49R, V60I, D121H, K122E, T131TP, I135T, K173S, Q174K, D177E, V179I, I202V, Q207A, K238R, V245E, T286TA, E291D, I293V, E312N R125*K 
RS11000495 RS11_495 AZT, 3TC EFV, NVP K65R, M184V K103N, E138A K11T, K20R, V21I, V35T, T39N, V60I, K122E, D123N, T131TP, K173S, D177E, T200K, I202V, Q207E, R211K, V245Q, E248D, S251Q, A272P, K275R, K277R, T286A, E291D, V292I, E312D  
RS11000504 RS11_504 AZT, 3TC NVP   V35T, T39TI, K49R, V60I, K64R, K122E, D123DN, I135T, K173S, Q174K, D177E, V179I, Q207A, R211RK, V245Q, E248ED, T286A, E291D, I293V, P294T, E312D, V317VA  
RS11000505 RS11_505 AZT, 3TC NVP   V35T, E40ED, K49R, V60I, K122E, I135T, S162C, E169D, D177E, I178L, Q207E, R211K, I244V, V245VE, D250E, A272P, K277R, L282C, L283I, I293V  
RS11000508 RS11_508 AZT, 3TC NVP   K22R, E28Q, K32Q, V35T, K49R, V60I, K122E, D123S, T131TP, I135T, Q145C, S163T, K173A, Q174K, D177E, I178IM, T200A, Q207A, R211S, V245M, D250E, A272P, T286A, A288G, E291D, V292I, I293V, E312D  
RS11000510 RS11_510 AZT, 3TC NVP M184V G190A K20R, V21I, I31L, V35T, E36D, T39R, K43E, K101Q, K102R, D121H, K122E, T165I, K173A, D177E, V179I, T200E, I202V, Q207A, R211K, L228R, K275Q, T286A, E291D, V292I, I293V, P294T, E312D  
RS11000515 RS11_515 AZT, 3TC NVP   E6D, E28EA, V35T, E36D, K49KR, K122E, D123S, I135T, S162A, K173S, Q174K, D177E, V179I, Q207A, R211K, V245I, D250E, T286A, E291D, V292I, I293V, E312D  

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