Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Hardy (2015)
Title Evolution of a novel pathway leading to dolutegravir resistance in a patient harbouring N155H and multiclass drug resistance.
Citation J Antimicrob Chemother
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 8
NumPts 1
Subtype B

 

Clinical IN Isolates


SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
Pt1INT Pt1INT0908 None   E157Q R20K, V31I, L45I, L101I, K111KR, I135IV, K160Q, V201I, K215N, A265AV  
  Pt1INT1001 RAL 16  E157Q R20RK, V31I, L45I, L101I, T122TI, I135IV, K160Q, V201I, K215N, A265V  
  Pt1INT1003 RAL 22 N155H E157Q R20K, V31I, L45I, L101I, I135IV, K160Q, V201I, K215N, A265V  
  Pt1INT1102 RAL 28  E157Q R20K, V31I, L45I, L101I, I135V, V151VI, K160Q, V201I, K215N  
  Pt1INT1202 RAL, DTG 69 N155H E157Q R20K, V31I, L45I, L101I, S119SR, I135V, V151I, K160Q, V201I, K215N  
  Pt1INT1212 RAL, DTG 110 E138K, S147G, N155H T97A, E157Q D6DN, R20RK, V31I, L45I, L101I, S119R, I135V, V151I, K160Q, V201I, K215N  
  Pt1INT1310 RAL, DTG 157 E138K, S147G, N155H T97A, E157Q R20K, V31I, L45I, A49P, L101I, S119R, T122X, I135V, V151I, K160Q, V201I, K215N, L234V  
  Pt1INT1401 RAL, DTG 168 E138K, S147G, N155H T97A, E157Q R20RK, V31I, L45I, A49P, L68LF, L101I, S119R, T122X, I135V, V151I, K160Q, V201I, K215N, L234V  

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