Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Nerrienet (2014)
Title HIV-1 protease inhibitors resistance profiles patients virological failure LPV/r based 2nd line regimen Cambodia.
Citation J AIDS Clin Res
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 71
NumPts 71
Subtype CRF01_AE, A

 

Clinical PR Isolates


SubjectIsolatePIsWksPIMajorPIMinorCommonUnusual
5 5 LPV    W6R, Q18R, K20R, E35D, M36I, R41K, H69K, K70R, I72E, L89I V77E, T80A, L90W, T91P 
P1216163 P1216163 LPV    I13V, E35D, M36I, R41K, H69K, L89M V75VA 
Q0208194 Q0208194 LPV  I54V, V82A L10FV, L33F, T74P I13V, G16GE, K20R, E35D, M36I, N37D, R41K, L63C, H69K, L89M  
Q0424292 Q0424292 LPV    T4I, L5F, R8G, T12P, I13V, G16E, E35D, M36I, R41K, H69K, L89M  
Q0703207 Q0703207 LPV    K20R, E35D, M36I, R41K, H69K, L89M  
Q0704084 Q0704084 LPV    E35D, M36I, R41K, R57K, H69K, L89M R87RQ 
Q0814184 Q0814184 LPV    I13V, E21EK, M36I, R41K, H69K, L89M R87RQ 
Q0818148 Q0818148 LPV  I54IV  L5LF, E35DN, M36I, R41K, L63C, H69K, L89M  
Q0920081 Q0920081 LPV  M46I, I54V, V82S L24I, Q58E, L89V L10I, I13V, K20KR, L33I, E35D, M36I, N37DE, K55KR, R57K, I62V, L63P, H69K, T74S  
Q1019297 Q1019297 LPV    E35D, M36I, R41K, H69K, L89M  
R0115235 R0115235 LPV    I13V, L33V, E35D, M36I, R41K, L63P, H69K, L89M  
R0130090 R0130090 LPV  M46I, L76V, I84V L10F I13V, G16E, E21K, E35D, M36I, R41K, H69K, I72R, L89I  
R0326191 R0326191 LPV    I13V, G17E, K20KI, E35D, M36I, R41K, R57K, H69R, K70KR, L89M  
R0606212 R0606212 LPV  I54V, V82A L10F, N83D I13V, K20R, A22V, M36I, N37D, R41K, L63LP, H69K, L89I, T91A  
R0712188 R0712188 LPV  M46I, G48V, I54V, L76V, V82T L89V L10R, I13A, K14R, K20I, E35D, M36I, N37D, R41K, K55N, D60E, L63P, H69K, K70R, A71V, T91A, Q92K  
R0917161 R0917161 LPV    L10I, I13V, G16E, M36I, R41K, H69K, L89I  
R1113090 R1113090 LPV  M46I, I47V, L76V, I84V L10F I13V, G16Q, L19V, K20I, E35D, M36I, P39S, R41K, K55R, D60E, I66F, H69K, A71AV, L89M  
S0428149 S0428149 LPV  M46I, L76V, I84V F53L L10I, I13V, I15V, K20I, E35D, M36I, R41K, K55R, D60E, L63P, I66F, H69K, K70R, L89M  
S0610136 S0610136 LPV    G16E, E35D, M36I, R41K, D60E, H69K, L89M, I93L  
S0613189 S0613189 LPV  V82A  L10V, I13V, G16E, K20R, E35D, M36I, R41K, L63C, H69K, T74A, L89M  
S0709407 S0709407 LPV    I13V, E35D, M36I, R41K, R57K, H69K, V82I, L89M  
S0721226 S0721226 LPV    Q18E, M36I, R41K, L63P, H69K, L89M, I93L  
S0723170 S0723170 LPV    L10I, I13V, M36I, R41K, L63P, H69K, L89M, Q92K  
S0815116 S0815116 LPV  V32I, I47A L10F I13V, M36I, R41K, H69K, L89I  
S0822156 S0822156 LPV  M46L, I47V, G48V, I54V, V82T, I84V F53L, L89V L10I, I13A, K20I, M36I, R41K, L63P, I66F, H69K, A71V  
S0916071 S0916071 LPV  M46I, I54V, V82F, L90M  L10V, K20I, E35D, M36I, R41K, Q61H, I62V, L63C, H69K, T74S, L89I  
S1119066 S1119066 LPV    L10I, I13V, E35D, M36I, N37D, R41K, H69K, K70R, L89M  
S1201062 S1201062 LPV    T12A, I13V, K20I, E35D, M36I, R41K, L63LP, H69K, K70KR, V82VI, L89M  
T0108121 T0108121 LPV    I13V, I15IV, E35D, M36I, R41K, L63C, H69K, L89M P81PL 
T0130214 T0130214 LPV    L10LI, E35D, M36I, R41K, K45R, L63Q, H69K, L89M, I93M  
T0202184 T0202184 LPV    E21EK, E35D, M36I, R41K, L63LF, H69K, L89M, I93L G16EK, R87RQ 
T0226205 T0226205 LPV    I13V, G16E, K20R, E35D, M36I, P39PS, R41K, K45KR, R57K, H69K, K70R, I72V, V77VI, L89M  
T0311137 T0311137 LPV    I13V, M36I, R41K, H69K, L89M  
T0317187 T0317187 LPV    L10LI, T12A, I13V, G16E, E35D, M36I, N37D, R41K, R57K, H69K, L89M  
T0320107 T0320107 LPV    I13V, E35D, M36I, R41K, H69K, L89M  
T0427315 T0427315 LPV    I13V, K20I, M36I, N37D, R41K, H69K, L89M  
T0428167 T0428167 LPV    I13V, M36I, R41K, H69K, V82I, L89M  
T0430202 T0430202 LPV    I13V, I15V, E35D, M36I, N37ND, R41K, D60E, H69K, L89M  
T0506285 T0506285 LPV  M46I, I47V, I54V, I84V L10F, L24I K20I, E35N, M36I, K55R, I62V, L63P, H69K, A71V, T74A, L89M, I93L  
T0518207 T0518207 LPV  M46MI, I54V, V82A L10F, Q58E I13V, L33LI, E35D, M36I, H69K, K70R, L89I  
T0528149 T0528149 LPV   L33F I13V, R41K, K43R, L63I, I64V, H69K, K70R, L89M, I93L  
T0622115 T0622115 LPV    L10LI, I13V, G16E, E35D, M36I, R41K, I62IV, L63T, E65ED, H69K, T74S, L89M  
T0630085 T0630085 LPV  M46I, I50V, I54V, V82A L33F, T74P L10I, I13V, G16A, M36I, R41K, L63V, H69K, K70R, L89M  
T0702093 T0702093 LPV    I13V, E35D, M36I, R41K, H69K, V82I, L89M  
T0807129 T0807129 LPV  M46I, I47V, L76V, V82F Q58E L10I, I13V, G16E, K20I, E35DN, M36I, N37ND, K55R, L63T, I64V, H69K, I72T, L89M  
T0826079 T0826079 LPV  M46I, I47A, I84V, L90M L10F, F53L I13V, G16A, L19I, L33I, E35D, M36I, N37D, R41K, R57K, Q61N, L63P, C67F, H69K, K70R, L89I, T91V  
T0905041 T0905041 LPV    L10IV, I13V, G16E, E35D, M36I, R41K, L63T, H69K, K70R, L89M  
T0910001 T0910001 LPV  M46I K20T L10V, I13V, G16E, M36I, G40R, R41K, H69K, L89M  
T0914094 T0914094 LPV    L10I, T12A, I13V, G16E, E35D, M36I, R41K, R57K, H69K, K70R, I72IV, L89M  
T0929127 T0929127 LPV  I54V, V82A L10F T12P, I13V, G16E, K20R, E35D, M36I, R41K, K45I, L63T, H69K, L89M  
T1005142 T1005142 LPV  M46I, I54V, V82A, L90M  L10V, G16E, K20R, E35D, M36V, P39S, R41K, K55R, I62V, L63P, H69K, A71V, I93L  
T1008239 T1008239 LPV    L10LI, T12P, I13V, G16GE, E35D, M36I, R41K, L63ST, H69K, K70R, L89M  
T1022129 T1022129 LPV  M46L, I54V, I84V L10F, Q58E, N83D, L89V T4P, V11I, I13V, K14R, K20R, A22V, L33I, E35S, M36I, R41K, D60E, I62V, L63P, H69K, A71V, Q92E T91G 
U0129166 U0129166 LPV    I13V, G16E, K20I, E35D, M36I, R41K, R57K, D60E, H69K, K70R, I72IV, L89M  
U0218166 U0218166 LPV    L10I, I13V, G16E, K20I, E35D, M36I, R41K, L63C, K70R, L89M H69E 
U0223070 U0223070 LPV  I54V, V82A, L90M L10F, K43KT, L89V I13V, G16E, K20I, E35D, M36I, N37D, R41K, Q61H, L63R, H69K, A71T, T91S  
U0302042 U0302042 LPV  M46I, I54V, V82A, L90M L10F, K43T, N88D, L89T V11L, I13V, L19LV, K20V, L33I, E35D, M36I, N37D, R41K, K55R, L63P, H69K, K70T, A71V, T74S, T91A  
U0302193 U0302193 LPV    E35D, M36I, R41RK, L63C, H69K, L89M  
U0316214 U0316214 LPV  G48V, I54V, V82A L89V T4S, L10I, V11L, I13V, K20I, E35D, M36I, I62IV, L63P, H69K, A71T  
U0329191 U0329191 LPV    E35D, M36I, R41K, L63C, H69K, L89M  
U0331085 U0331085 LPV  M46I, I54IV, V82A  I13V, G16E, K20R, E35D, M36I, R41K, H69K, K70R, L89M  
U0401148 U0401148 LPV    L10V, E35D, M36I, R41K, R57K, I62IV, L63C, H69K, T74S, L89M  
U0406170 U0406170 LPV    E35D, M36I, R41K, L63P, H69K, V82I, L89M, I93L  
U0406184 U0406184 LPV    I13IV, K20R, M36I, R41K, I64IV, H69K  
U0407179 U0407179 LPV  M46I, I84V, N88G, L90M L10F, K20T, L33F, F53L, Q58E, G73GS, L89V I13V, E35D, M36I, R41K, K55R, R57K, L63P, I66IF, H69K, A71V  
U0519246 U0519246 LPV  V82A  L10I, I13V, G16E, K20R, E35D, M36I, R41K, L63T, H69K, T74A, L89M, I93V  
U0527075 U0527075 LPV  M46I, I47V, L76V, I84V F53L, Q58E, L89V L10V, I13A, G16E, K20I, L33I, E35D, M36I, N37H, P39S, R41K, K55R, D60E, Q61H, I62V, I66F, H69K, K70R, A71V  
U0719200 U0719200 LPV  M46I, I47A, I84V, L90M L89V L10V, I13A, K20I, M36I, K55R, L63P, H69K, A71V, I93M  
U0831207 U0831207 LPV    K20R, E35D, M36I, R41K, L63C, G68GE, H69K, L89M, I93L  
U0907156 U0907156 LPV  V32I, M46I, I47V, I54M, L90M L33F, Q58E, G73GD, N83D L10V, I13V, G16A, M36I, N37D, R41K, K55R, D60N, L63P, I64V, H69K, K70R, A71IV, L89I  
U0921069 U0921069 LPV   M46MV I13V, G16GR, M36I, R41RK, H69K, L89M T31TI, G94GA 

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