Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Pircher (2013)
Title Molecular characterization of HIV type 1 in Brazzaville, Republic of Congo, and first data on resistance to antiretroviral drugs.
Citation ARHR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 77
NumPts 77
Subtype G, A, CRF02_AG, B, CRF45_cpx, H, J, D, A + G, F, CRF09_cpx, CRF49_cpx, CRF05_DF, CRF18_cpx, C, CRF01_AE

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
A1001 A1001 None None K219N  K20R, V35P, V60I, K102Q, K104R, K122E, D123G, S162A, K173I, Q174K, D177E, I178M, T200A, Q207V, R211K K70I 
A1002 A1002 None None   K32Q, V35T, P119PS, K122Q, D123N, I135V, S162A, K173A, Q174K, D177E, R211A, T216TP, P243T, V245H  
A1003 A1003 None None  K103N, V106I, G190A V8I, K30KE, V35T, I50M, V60I, V90I, I135V, K173A, Q174K, D177E, T200A, Q207D, R211K  
A1004 A1004 None None   V35T, V60I, K122E, D123DE, I135V, I142V, N175H, D177E, I178V, E194D, T200A, E204K, Q207E, F214L  
A1005 A1005 None None   V35T, T39A, S48T, K122E, D123G, K166R, K173T, D177E, T200A, Q207N, R211K  
A1006 A1006 None None  A98G, K101E, E138Q V21I, V35T, E40D, K49R, V60I, K173T, Q174K, D177E, V179I, T200A, Q207D, R211K E169EV 
A1011 A1011 None None   V21I, V35T, T39M, V60I, K173T, Q174R, D177E, I178IM, I195K, T200A, Q207E, R211A  
A1012 A1012 None None   E6D, K11T, V35T, K49R, V60I, D121Y, K122E, A158S, D177E, I178M, T200A, Q207A, R211K, F227Y  
A1013 A1013 None None  E138A V35T, A98S, D123E, I135V, S162C, K173A, Q174K, V179I, T200TA, Q207EG, R211K, V245Q, E248D  
A1015 A1015 None None   E6D, A33S, V35T, T39A, E40D, K122E, D123N, I142T, T165I, D177E  
A1018 A1018 None None   K11Q, K20R, K22KN, V35T, K122E, D123N, I135R, I142V, S162A, K173IT, Q174EK, G196E, T200A, I202V, Q207E, F214L N175NK 
A1020 A1020 None None   K11T, K20R, E29EK, V35T, T39K, D121H, K122E, D123S, T131TP, I135R, K173S, Q174K, D177E, T200I, I202V, Q207A, R211S, F214L, V245Q, E248D  
A1021 A1021 None None Y115YF  V35T, E40D, K49KR, V60I, D121H, K122KE, T131TP, I135T, K173L, Q174K, D177E, V179I, S191SF, T200A, K201R, Q207A, R211S, P243S, V245K, D250E  
A1022 A1022 None None   E6D, K11H, V35T, K49R, V60I, K104R, D121Y, K122E, D177EG, T200A, Q207E, E248N Q258K 
A1023 A1023 None None  A98AG E6D, K11T, V35T, T39A, D121Y, K122E, D123G, A158S, K173T, Q174K, D177E, I178M, T200A, Q207E  
A1026 A1026 None None   V35T, T39L, K122KE, I135T, I142V, S162A, K173T, Q174K, D177E, T200A, Q207E, R211RK, V245Q, E248D  
A1028 A1028 None None   K11A, V35T, T39AD, K122KE, D123N, I142IV, K173T, Q174K, T200AV, Q207QE, R211K, P243S, V245Q, E248D, D250E  
A1029 A1029 None None   V35T, T39A, S48T, I135T, T165I, F171Y, K173T, D177E, T200E, I202V, Q207K, P243T, V245Q  
A1031 A1031 None None   V35T, K49KR, V60I, K102Q, T107S, S162C, K173R, Q174K, D177E, I178M, T200A, Q207DN, H208HY, R211K  
A1032 A1032 None None   V35T, E36D, T39K, V60I, K102Q, K122E, D123G, S162C, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, V245Q, E248N, D250E  
A1033 A1033 None None   V35T, T39N, E40D, V60I, V90I, K122E, D123X, I135V, S162C, K173A, D177E, V179VI, T200A, Q207E, R211K  
A1035 A1035 None None   V21I, V35T, T39A, E40D, V60I, K102Q, K173T, Q174K, D177E, I178M, T200A, Q207K, R211T, I244V, V245Q, E248D, D250E  
A1036 A1036 None None   P4H, E6A, V21I, V35T, K49R, V60I, T165I, K173T, D177E, T200A, I202V, Q207A, R211Q L120LV 
A1037 A1037 None None   K11I, V35T, K49R, K122E, D123N, S162D, K173S, D177E, V179I, Q207A, R211S, V245E, D250E  
A1038 A1038 None None   E29EK, V35T, E36D, D121DN, K122E, D123G, R125RK, I135V, S162A, K173AT, Q174K, D177E, T200A, Q207D, R211K, V245Q  
A1041 A1041 None None   V35T, E36D, K49R, V60I, D121DN, K122E, D123N, I135T, A158AS, S162X, K173I, Q174K, D177E, T200A, Q207A, R211S, I244V, V245M, E248K, D250E  
B1101 B1101 3TC, D4T, AZT NVP K70R, M184V, T215F, K219Q K103N, K238T E6A, E28K, K32E, V35T, T39N, E40D, V60I, D67X, S68SG, K122E, D123S, K173A, D177E, I178L, S191SF, G196E, Q197E, T200A, K201R, E204N, Q207A, R211K, V245Q H96HP 
B1102 B1102 3TC, D4T, AZT NVP M41L, D67DN, M184V V106A, F227L K20KR, V35T, T39L, S48T, V60I, V90I, V118I, K122E, I135IV, D177E, T200E, E203K, Q207E, R211K, T215X, K223KQ, V241VL, V245Q, E248R, K249Q  
B1103 B1103 3TC, D4T, AZT NVP M184V, T215F Y181C E6N, T7TP, P9S, E28K, V35T, T39K, E40D, V90I, K101N, K122E, D123S, S162Y, K166R, K173T, D177E, T200A, Q207E, R211K, V241L, V245Q, E248D, D250E  
B1104 B1104 3TC, D4T, AZT NVP M41L, M184V, T215F K103N V35R, T39A, S48T, V60VI, V118I, K122E, D123N, I135T, S162A, T165L, K173N, Q174K, T200A, E203G, Q207E, R211K, F214L, P243T, V245K, D250E  
B1105 B1105 3TC, D4T, AZT NVP M184V K101H, G190S V35T, D123E, K173L, Q174K, D177E, V179T, Q207E, R211Q, Q222H  
B1106 B1106 3TC, D4T, AZT NVP M41L, D67N, M184V, L210W, T215Y A98G, Y181C, H221Y V35T, T39N, E44D, K122E, D123S, I135T, K173R, Q174N, D177E, I178M, T200A, E203K, Q207D, R211K, V245T, E248D, D250E, L260V  
B1107 B1107 3TC, D4T, AZT NVP M41L, D67N, T69D, M184V, L210W, T215Y A98G, K103N V35T, T39A, E44D, V60I, V111I, D123E, I135L, K173T, Q174EK, D177E, G196E, T200K, I202V, Q207E, R211K, V245Q, E248D, D250E, S251C  
B1108 B1108 3TC, D4T, AZT NVP D67N, K70R, V75A, F77L, Q151M, M184V, T215I, K219Q V179E, Y181C, G190A V35T, T39N, K46KQ, V60I, K101R, K103R, V111I, K122E, D123S, I135T, I142V, K173A, T200A, Q207E, R211K, F214L, D218E, L228H, V245Q K73L 
B1110 B1110 3TC, D4T, AZT NVP K70R, M184V, K219Q K103N T27S, V35T, T39KN, V60I, V90I, K122E, D123S, I135T, S162Y, K173A, Q174K, T200A, Q207D, R211K, D218E, L228H, V245Q, E248D Q258E 
B1111 B1111 3TC, D4T, AZT NVP M184V K103N P4S, V35T, V60I, S68G, V90I, K122E, D123S, T131TP, T139R, S162C, K173A, D177E, I178M, T200A, Q207K, R211K, V245Q, E248D, D250E, S251A, W252G T128TP 
B1112 B1112 3TC, D4T, AZT NVP K70E, M184V A98G, E138A, V179E, G190S K20R, K22R, V35T, E36K, T39D, E40D, V60I, W88C, K102Q, K122P, T139V, K173T, Q174K, D177E, T200A, E203K, Q207E, F214L, V245Q  
B1113 B1113 3TC, D4T, AZT NVP M41L, D67N, L74V, M184V, L210W, T215Y, K219KN K103N, M230L, K238T I2IV, E6D, K20R, E28K, K32E, V35T, E36ED, T39K, K43E, E44D, K49R, V60I, K64R, V111I, V118I, K122KE, D123DN, K173A, Q174K, Q207A, H208HY, R211RK, V245E  
B1114 B1114 3TC, D4T, AZT NVP M41L, D67N, K70R, L74I, M184V, T215F, K219Q G190A V35T, T39D, V60I, K64KR, A98AS, K122E, D123S, I135T, I142V, K173AT, S191SF, T200D, E203EK, Q207A, V245Q, D250E  
B1115 B1115 3TC, D4T, AZT NVP M41L, D67G, M184V, T215F A98G, V108I, Y181C, G190A, H221Y P4S, E6D, L34I, V35T, T39L, E44D, V60I, S68G, K102Q, K122E, D123S, I135T, S162Y, K173T, Q174N, S191SF, I195L, T200A, E203A, Q207E, R211K, F214L, D218E, K219G, V245Q  
B1116 B1116 3TC, D4T, AZT NVP M41L, D67N, L74LV, M184V, L210SW, T215FY K103N, V106I, V108I, H221HY V35T, T107A, V118I, K122E, D123E, K173I, Q174K, D177E, I202V, E203X, Q207E, R211K, K223KE, V245Q, E248D  
B1117 B1117 3TC, D4T, AZT NVP M41L, T69D, V75M, M184V, L210W, T215Y A98G, V106I, Y181C I31L, V35IT, T39A, E44D, V60I, K101Q, V118I, P119PS, D121C, K122E, S162N, Q174K, D177E, I178V, T200E, K201M, E203K, E204Q, Q207A, R211K, K223T, L228R, V245T  
B1118 B1118 3TC, D4T, AZT NVP D67N, K70R, M184V, T215F, K219Q A98G, V106A, F227L K20R, V35T, T39L, K49R, V60I, I94L, V118I, D121Y, K122E, I135L, E169D, K173R, D177E, I178L, T200E, E204K, Q207E, R211K, F214L, V245T, E248I  
B1119 B1119 3TC, D4T, AZT NVP M41L, M184V, T215Y V108I, Y181C, G190A, H221HY, F227FL E6ED, V35T, T39K, K43E, K49R, T69N, K101Q, L109LI, K122E, S162SN, K173A, Q174K, D177E, T200A, E203V, Q207A, R211N, V245E  
B1120 B1120 3TC, D4T, AZT NVP M41L, L74LI, M184V, L210LW, T215Y, K219R K103N, V108I, H221Y, F227L K20KR, V35T, T39N, V60I, T107S, V118I, K122E, D123S, S162C, K173A, Q174K, T200A, Q207A, R211N, K223KE, L228LR, V245QR, E248D, D250E  
B1122 B1122 3TC, D4T, AZT NVP M184V V106A, H221Y, F227L E6D, V35T, K49R, I50V, T58S, V60I, T69N, W88C, T107S, D121Y, K122E, V148VG, S162SN, Q174L, D177E, S191SF, T200A, Q207D, R211K, F214C, D237A, I244V, V245K  
B1123 B1123 3TC, D4T, AZT NVP M41L, V75M, M184V, L210W, T215Y K103N, V108I, E138G, Y181C, H221Y V35T, K49R, V60I, T107S, L109I, D121DN, K122E, D123S, R125RK, D177E, I178M, T200E, Q207S, R211K, V245Q, D250E Q182QP 
B1124 B1124 3TC, D4T, AZT NVP M184V, T215FY K103KN, V108VI, Y181V V35T, K49R, V60I, D121H, D123DE, I135T, S162D, D177E, E203D, Q207E, R211K, V245Q, D250E  
B1125 B1125 3TC, D4T, AZT NVP L74I, M184V, T215FY, K219KN A98G, K101E, V108I, E138A, H221Y, M230L K22R, V35T, T39L, S68G, K104R, K122E, D123S, S162A, Q174K, T200A, E203D, Q207D, V245Q  
B1126 B1126 3TC, D4T, AZT NVP M41L, D67N, K70R, M184V, T215Y K103N, V106A, P225H, F227L P4PS, K20R, V35T, T39N, E40D, P119PS, K122E, V148G, K173A, Q174K, D177E, I178L, S191SF, T200A, Q207N, R211K  
B1127 B1127 3TC, D4T, AZT NVP A62AV, K70KR, M184V, T215TN Y181C E6K, K20R, V21I, V35T, T39K, K43E, K102KQ, K122E, K173A, D177EG, T200A, Q207E, R211K, D218DE, V241M, V245Q, E248D  
B1128 B1128 3TC, D4T, AZT NVP D67DG, M184V, T215Y K101E, G190A E6D, K11T, E28K, V35T, T39N, D86DE, D123N, K166R, D177E, I178F, V179T, T200A, Q207A, R211K  
B1129 B1129 3TC, D4T, AZT NVP M41ML, M184V K101H, Y181C, H221Y K20R, V35T, T39K, K43E, V60I, D121H, K122E, D123S, I135T, K166R, Q174E, D177E, E194ED, T200A, Q207E, R211K, F214L, T215X, V245Q, E248D, D250E L149LV 
B1131 B1131 3TC, D4T, AZT NVP  K103N, Y181C, H221Y P14T, K20R, V35T, D123E, I135V, S162C, K173I, Q174K, V179VI, T200A, Q207A, R211S, V245Q  
B1132 B1132 3TC, D4T, AZT NVP M184V, T215F K103KN, V106VA, M230L V35T, K49R, V60I, K122P, D123DN, I135IV, S162C, D177G, E194EK, G196E, T200A, Q207E, R211K, F227FY, L228R, K238R, P243T, V245Q, E248D  
B1133 B1133 3TC, D4T, AZT NVP M184V K103N, K238KT V35IR, T39N, E40D, V60I, K104R, D121Y, K122E, I135IT, T139TK, I142V, S162SA, D177E, T200A, Q207E, R211K, V245Q, E248D, D250E  
B1134 B1134 3TC, D4T, AZT NVP M184V K103N V35T, T39K, E40D, K43Q, K49R, K122E, D123S, I135T, K173L, D177E, I178L, Q207A  
B1135 B1135 3TC, D4T, AZT NVP M184V Y181C, H221HY L34LI, V35T, K49R, V60I, K104R, K122P, I135IT, K166KR, F171Y, Q174K, D177E, T200A, Q207E, R211K, V241VL, V245Q, E248D, D250E  
B1137 B1137 3TC, D4T, AZT NVP M41ML, M184V, L210W, T215Y A98G, K103N, V108I K20R, V35T, E36D, T39LS, K43KE, V60VI, L109LI, D123E, I135T, S162AT, K173T, Q174K, N175NY, D177E, G196E, T200A, Q207E, R211K, V245Q  
B1138 B1138 3TC, D4T, AZT NVP  K103N E6EQ, K20KR, V35T, T39N, V60I, S68G, T69N, K102Q, K122E, D123N, K173A, D177E, G196E, T200A, Q207K, R211E, V245Q K11LS 
B1139 B1139 3TC, D4T, AZT NVP M41ML, D67DN, M184V, T215Y V108I, V179E, H221Y K11T, E28KR, K32E, V35M, S68SG, T107A, D123N, I135IV, I142V, K173S, Q174K, D177E, I178L, G196K, I202V, Q207E, R211K, V241I, V245Q, D250E Q258K 
B1141 B1141 3TC, D4T, AZT NVP   K11T, V60I, D121H, K122E, I135T, I142V, S162A, D177E, T200A, Q207A, R211K, I244IV, V245K, E248D, D250E I167IT 
B1142 B1142 3TC, D4T, AZT NVP M184V V108VI, Y181C, H221Y K32R, V35T, E36ED, K49R, V60I, V118I, D121C, K122E, I135T, K166R, E169D, D177E, I178L, V179I, T200I, E204K, Q207E, R211K, F214L, V245Q, E248N, D250E  
B1143 B1143 3TC, D4T, AZT NVP D67DN, M184V K103N, Y181C P4S, P19Q, V21F, V35T, T39D, K49R, V60VI, K122E, D123N, I135T, T139R, D177E, T200A, I202V, Q207K, R211T  
B1144 B1144 3TC, D4T, AZT NVP   V35T, K49R, I50V, V60I, K173Q, D177E, V179I, Q207E  
B1145 B1145 3TC, D4T, AZT NVP M41ML, T69DN, K70KR, M184V K101E, V108I, E138A, H221Y, F227L, M230L V35T, V60I, K122E, D123N, D177E, I178M, T200E, I202IV, Q207K, R211A, T215X, L228LH, V245K  
B1146 B1146 3TC, D4T, AZT NVP M184V, T215Y K103N, V108I V35T, V60I, K102Q, D123E, T165L, K173T, Q174K, D177E, T200A, Q207D, R211K, V245Q, E248D, D250E  
B1147 B1147 3TC, D4T, AZT NVP M184V K103N, P225H I5V, K11T, K20R, V35T, T39N, E40D, V60I, K102Q, D121H, K122E, D123S, I135L, K173A, Q174K, D177E, G196E, Q207A, R211K, V245K, E248D, D250E  
B1148 B1148 3TC, D4T, AZT NVP D67DN, K70KR, M184V Y181C V35T, T39K, K43E, K101KR, K122E, D123N, A158T, S162A, K173S, Q174A, D177E, Q207A, R211K  
B1151 B1151 3TC, D4T, AZT NVP D67DN, K70R, M184V, K219KQ V108I, H221Y, F227L V35T, T39A, E40D, V60VI, D121H, K122E, I135T, T139KR, K173T, Q174K, D177E, Y188W, T200A, Q207E, R211RK, V245Q  
B1152 B1152 3TC, D4T, AZT NVP M41L, D67N, K70R, M184V, T215F, K219Q A98G, K101E, G190A E6D, K11Q, E28K, K32E, V35T, T39M, K43N, V60I, T69S, V75VL, K122E, D123N, F171Y, K173T, Q174K, D177E, I178M, V179VI, R211K, L228Q, V245Q, E248N, D250E  
B1153 B1153 3TC, D4T, AZT NVP M184V, K219KN Y181C V35S, K49R, K104R, K122E, D123N, K173A, D177E, T200E, Q207E, L210M, R211K, K223KQ  
B1154 B1154 3TC, D4T, AZT NVP M184V  E6KT, K11KT, V35T, T39R, K122E, D123S, A158S, K173S, Q174K, D177E, G196E, T200A, I202V, Q207N, R211K, V245E, D250E  
B1155 B1155 3TC, D4T, AZT NVP D67N, K70R, M184V, T215F, K219E K103N, V108VI, Y181C, H221Y E6D, L34I, V35T, V60I, K64KR, K122P, I135T, S162A, Q174A, D177EG, V179VI, V189VI, G196E, T200A, E203EG, Q207E, R211K, V245Q  
B1156 B1156 3TC, D4T, AZT NVP  K103N V35T, T39N, V60I, D121H, K122E, I135V, I142IV, K173R, Q174K, D177E, I178M, S191SF, Q197E, T200A, Q207D, R211RK, V245Q  
B1157 B1157 3TC, D4T, AZT NVP M184V K103N V35T, K49R, V60I, D121DN, K122E, I135T, T139K, S162C, K173T, Q174K, D177E, G196E, E203D, Q207E, V245Q, E248D, D250E  
B1158 B1158 3TC, D4T, AZT NVP D67N, T69D, K70R, M184V, T215F, K219Q K103N, K238N K20R, E28A, V35T, T39N, V60I, A98S, K122E, D123N, I135T, K173A, D177E, S191SF, T200A, Q207E, R211K, V245K H96HP