Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Afonso (2012)
Title HIV-1 genetic diversity and transmitted drug resistance mutations among patients from the North, Central and South regions of Angola.
Citation PLoS ONE
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 101
NumPts 101
Subtype C, H, F, G, A, CRF02_AG, CRF18_cpx, D, A + G, B, G + Unknown, G + H + J, K, CRF04_cpx, CRF09_cpx, J, CRF25_cpx, CRF01_AE, CRF49_cpx

 
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Page 1   listing Isolate 1 to Isolate 100 from Total 101 Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
ANG1 ANG1 NRTI NNRTI   E6A, V35T, E36A, T39D, S48T, V60I, K122E, D123N, I142T, K166R, K173T, D177E, I178L, T200A, Q207E, R211K, V245K  
ANG100 ANG100 NRTI NNRTI   V35T, E36D, V60I, K64R, V90I, A98S, D123E, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, P243T, V245Q, E248D  
ANG101 ANG101 NRTI NNRTI   K20R, V35T, T39A, E40D, V60I, S162A, K173T, Q174K, D177E, V189I, T200A, I202V, Q207E, V245Q, L246I, D250E S251L, W252L 
ANG103 ANG103 NRTI NNRTI   V35T, V60I, K122P, I135V, S162C, Q174R, D177E, I178M, Q207E, R211K, V245Q, E248D  
ANG104 ANG104 NRTI NNRTI   E6D, V35T, T39N, E40D, S162A, K173T, D177E, G196K, T200A, Q207E, K238R, V245K, D250E, S251N  
ANG105 ANG105 NRTI NNRTI   V35A, T39E, S48T, V60I, K122E, D123S, I135R, S162Y, K173A, Q174K, D177E, T200A, Q207E, V245Q  
ANG106 ANG106 NRTI NNRTI   V35T, E44K, V60I, I135V, I142V, S162C, K173A, Q174K, I178L, T200A, Q207E, R211K, V245Q, E248D K32H 
ANG107 ANG107 NRTI NNRTI V75M, M184V V179D E6D, K11T, T27S, L34V, V35T, T39K, K43Q, D121H, K122E, D123G, I142T, S162C, T165K, K173Q, D177E, I178L, Q207T, R211K, I244V, V245K, D250E, S251N, I257L  
ANG108 ANG108 NRTI NNRTI   V35K, T39A, D123E, I135V, S162C, K173I, Q174K, T200E, Q207E, R211K, V245Q, D250E, S251N  
ANG11 ANG11 NRTI NNRTI M184V K101E, E138A, G190A V21I, V35T, D123N, I135V, S162C, Q174K, D177E, T200A, Q207D, R211K, P243S, V245H, E248D  
ANG110 ANG110 NRTI NNRTI   K20R, K32Q, V35T, T39L, I135V, I142T, S162C, K173V, Q174K, T200A, Q207A, R211A, V245Q, E248N, D250E, S251D  
ANG111 ANG111 NRTI NNRTI  K103N I5V, K20R, V35T, V60I, K122P, I135V, S162C, Q174E, D177E, T200S, Q207E, V245Q, E248D  
ANG113 ANG113 NRTI NNRTI   E6D, K11T, T27S, V35T, T39K, K43Q, D121H, K122E, D123G, I135T, S162C, D177E, I178M, V179I, Q207T, R211K, I244V, V245K, D250E, S251N  
ANG114 ANG114 NRTI NNRTI  M230I V35T, T39A, S68G, K122A, K173T, Q174K, D177E, I178L, G196E, T200S, Q207E, R211K, W229*, V245Q, E248D  
ANG12 ANG12 NRTI NNRTI  K103N K20R, V35T, T39A, E40D, K104R, P119S, K122E, D123S, S162C, T200A, Q207K, R211K S117F, V118S 
ANG13 ANG13 NRTI NNRTI  K103N K20R, V35T, T39A, E40D, K104R, K122E, S162A, K173I, Q174K, T200V, Q207A, R211K, V245Q, E248D, D250E, S251Q  
ANG14 ANG14 NRTI NNRTI  K103N K11T, K20R, V35T, T39G, K102Q, I135V, T165I, K173A, Q174K, D177E, I202V, E203Q, Q207D, R211K, F214L, V245Q, E248D  
ANG15 ANG15 NRTI NNRTI   V35T, T39K, K43Q, K49R, K122E, D123S, I135T, K173T, D177E, Q197K, T200A, Q207A, R211K, P243S, V245K, D250E  
ANG16 ANG16 NRTI NNRTI   V35T, E36D, V60I, K64R, V90I, A98S, D123E, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, V245Q, E248D, D250N  
ANG17 ANG17 NRTI NNRTI   V35T, E36V, T39E, S48T, K122E, D123G, K173A, Q174K, D177E, Q207E, R211K, F214L, V245Q  
ANG18 ANG18 NRTI NNRTI   K11T, V35T, D123N, I142V, K173V, Q174K, D177E, T200A, I202V, Q207A, R211S, F214L, V245Q, E248D, D250T  
ANG19 ANG19 NRTI NNRTI   K20R, L34I, V35T, T39S, K49R, I50V, V60I, K104R, V118M, K122E, D123N, I135T, D177E, I178M, T200A, E204Q, Q207E, R211K, F214L, I244V, V245K, D250E  
ANG2 ANG2 NRTI NNRTI   V35T, T39E, S48T, K122E, D123G, I135V, S162C, Q174R, D177E, T200V, Q207E, R211K, V245Q K173P 
ANG20 ANG20 NRTI NNRTI   V35T, E36D, E40D, K122E, D123G, S162A, K173G, Q174K, D177E, T200A, Q207E, R211S, V245Q, D250E, S251N  
ANG21 ANG21 NRTI NNRTI M184V Y181C E6A, V35T, K101Q, K122E, S162A, K173T, Q174K, T200A, Q207E, V245Q, D250E, S251H  
ANG22 ANG22 NRTI NNRTI   K11M, V35T, V60I, T107S, D121Y, K122E, D123G, D177E, I178M, T200A, Q207A, R211K, I244V, V245Q, E248D  
ANG24 ANG24 NRTI NNRTI   K20R, K32R, L34I, V35T, T39L, E40D, K49R, V60I, D121C, K122E, I142T, E169D, I178L, T200A, E204Q, Q207A, F214L, I244V, V245K, D250E  
ANG25 ANG25 NRTI NNRTI M184V K103N P4S, V35T, D123E, I135V, S162C, K173I, Q174K, D177E, I178L, T200A, Q207E, R211K, V245Q, E248N  
ANG26 ANG26 NRTI NNRTI   E6A, V35T, E36A, T39E, S48T, V60I, W88C, K122E, D123N, I142T, K173T, D177E, I178L, T200A, Q207E, R211K, V245K  
ANG27 ANG27 NRTI NNRTI   I5V, V35T, T39N, V60I, D121Y, K122E, D123E, I135V, T139M, I142V, S162A, T200A, Q207A, R211K, V245Q, L246I, E248D, D250E  
ANG28 ANG28 NRTI NNRTI T215Y  P4T, K11T, K20R, V35T, T39K, V60I, K122E, D123S, I135V, S162N, K173S, Q174K, D177E, G196E, T200A, Q207A, F214L, V245L N54Y 
ANG3 ANG3 NRTI NNRTI   P4S, V35T, T39A, K43R, S162C, K173A, Q174K, T200A, Q207E, R211K, F214L, E233D, V245Q, D250E  
ANG30 ANG30 NRTI NNRTI M41L, M184V, T215F Y181C, H221Y V35T, T39A, T107S, D121Y, K122E, I135V, K173T, Q174K, D177E, T200A, E203D, Q207E, R211K  
ANG31 ANG31 NRTI NNRTI   P4S, E6D, V35T, E40D, I135V, S162C, K173T, Q174K, D177E, I178L, T200I, Q207E, V245Q, E248N  
ANG32 ANG32 NRTI NNRTI D67G, K70R, L74I, M184V, T215F, K219Q K101E, E138G, G190A P4N, I31L, V35T, T39A, E40D, K49R, V60I, S68G, V90I, D121C, K122E, E169D, D177E, I178L, G196E, T200A, E203D, E204K, Q207D, R211K, F214L, V245T, E248D, K249R, D250K  
ANG33 ANG33 NRTI NNRTI   K11A, K32R, V35T, V60I, D121Y, K122E, S162A, K173T, D177E, T200A, Q207A, R211K, I244V, V245Q, E248D  
ANG34 ANG34 NRTI NNRTI   V35T, K49R, V60I, K173A, Q174K, D177E, T200A, Q207E, V245Q, E248D, D250E  
ANG35 ANG35 NRTI NNRTI   K11T, V35T, V60I, K122E, D123G, I135L, K173A, D177E, Q197P, T200A, Q207K, V245Q, D250E  
ANG36 ANG36 NRTI NNRTI M184I  V35T, K49R, V60I, Q91H, D121Y, K122P, D123E, S162C, Q174E, D177E, G196E, T200A, E204D, Q207E, P243A, V245K, D250E, S251D H96P, A98W, N136H 
ANG37 ANG37 NRTI NNRTI   P4T, E6D, K11A, V21I, V35T, T39K, E40D, K49R, E53D, V60I, D121Y, K122E, I135T, E169D, D177E, G196K, T200A, Q207D, R211K, I244V, V245K, D250E, S251H  
ANG38 ANG38 NRTI NNRTI  K103N V35T, K43R, K49R, D123E, I135V, S162C, K173T, Q174K, T200A, Q207E, R211A, V245H, E248D  
ANG39 ANG39 NRTI NNRTI   K11T, V35P, T39E, E53D, V60I, T107S, D121H, K122E, D123S, I135V, S162A, K173T, D177E, I178L, T200A, Q207A, R211K, P243A, I244V, V245K  
ANG4 ANG4 NRTI NNRTI   V21I, E28G, V35T, T39L, V60I, K122P, I135V, S162C, K173A, Q174K, D177E, I178M, Q207E, R211K, V245Q, E248D, D250E, S251D  
ANG40 ANG40 NRTI NNRTI   K11Q, V35T, T39K, E40D, V60I, W88C, K122E, D123N, K173A, Q174K, D177E, I202V, R211K, F214L, P243T, V245Q, E248D, D250E  
ANG41 ANG41 NRTI NNRTI  Y181C, H221Y V35T, V60I, T69S, T107S, K122E, D123S, I135T, I142V, K173S, Q174K, I178L, T200A, Q207A, F214L, I244V, V245T, D250E  
ANG42 ANG42 NRTI NNRTI M184V Y181C K11E, V35T, T39N, K49R, V60I, D121H, K122E, D123G, K166R, K173T, D177E, I178L, Q207E, V245E  
ANG43 ANG43 NRTI NNRTI   T27P, V35T, K104R, I135V, S162A, K173T, T200A, Q207E, V245Q, E248D, D250E, S251V  
ANG44 ANG44 NRTI NNRTI   P4S, K11A, V21I, T27S, V35T, T39R, E40D, K43Q, V60I, K122E, D123N, D177E, I178M, T200A, E204A, Q207D, R211K, P243T, I244V, V245K, D250E  
ANG45 ANG45 NRTI NNRTI D67N, K70R, M184V, T215F, K219Q K103S, G190A V35T, T39R, K46Q, K102Q, K122E, K173T, D177E, T200K, I202V, Q207N, R211K, F214L, V245K  
ANG46 ANG46 NRTI NNRTI M184V  I5V, V35T, S48T, K49R, V60I, K122P, D123E, I135V, S162C, K173L, Q174K, D177E, I178M, Q207E, R211K, V245Q, E248D  
ANG47 ANG47 NRTI NNRTI   I5V, V35T, S48T, V60I, K122A, D123E, I135V, S162C, K173S, Q174K, D177E, I178M, Q207E, R211K, V245Q, E248D  
ANG48 ANG48 NRTI NNRTI   K11T, V35T, T39K, V60I, T107S, D121Y, K122E, T165I, D177E, G196E, T200A, Q207D, R211K, V241I, I244V, V245K  
ANG49 ANG49 NRTI NNRTI M184V V106M, F227L E6K, V35T, K49R, V60I, K122E, I135T, A158S, S162A, Q174E, N175H, D177E, I178V, K201T, I202V, E204K, Q207E, F214L, V245K, D250E  
ANG5 ANG5 NRTI NNRTI   E6A, K11A, V35T, T39K, E40D, K43Q, K49R, V60I, K122E, D123G, I135T, A158S, E169D, K173T, D177E, T200A, Q207A, R211K, I244V, V245T, D250E  
ANG50 ANG50 NRTI NNRTI M184V, T215Y K103N P4T, K11T, K20R, V35T, T39K, K49R, V118I, K122E, D123N, I135T, K173A, Q174K, D177E, T200I, Q207A, R211N, F214L, V245Q, E248D  
ANG51 ANG51 NRTI NNRTI   V35T, D123E, I135V, S162C, K173A, Q174K, T200A, Q207D, R211K, V245Q, E248N  
ANG52 ANG52 NRTI NNRTI   V35T, G45E, V60I, K122E, D123S, I135V, I142V, S162C, T165I, Q174K, D177E, I178M, T200A, Q207K, R211N, V245Q, E248D, D250E  
ANG53 ANG53 NRTI NNRTI   P4T, K11T, V35T, T39K, K43Q, K49R, V60I, K104N, D121Y, K122E, D123G, I135T, T139M, I142V, K173T, Q174K, D177E, T200A, I202V, Q207T, R211K, F214L, I244V, V245K, D250E  
ANG54 ANG54 NRTI NNRTI M184V K103N S3T, V8A, K20R, K22N, V35T, E36A, T39E, E40D, E42D, S48T, K122E, D123G, I135L, K173A, Q174K, D177E, T200A, Q207G, V245Q K13M 
ANG55 ANG55 NRTI NNRTI   V35T, T39K, G112E, K122P, I135V, S162C, K173I, Q174K, T200A, Q207E, R211K, V245Q, E248N K32A 
ANG56 ANG56 NRTI NNRTI   V35T, T39A, E40D, E42K, G45E, K49R, V60I, D121Y, K122E, D123E, R125K, I135R, E169D, D177E, I178L, V179I, D192N, G196E, R199K, T200I, I202V, E204K, Q207E, R211K, F214L, D237N, V245T, D250E  
ANG58 ANG58 NRTI NNRTI M184V K101E, E138A, G190A K11S, V35T, T39N, V60I, K64R, W88C, K122E, D123S, K173T, Q174R, D177E, I178V, V179I, T200A, I202V, Q207D, R211K, I244V, V245Q, S251N  
ANG59 ANG59 NRTI NNRTI   K20R, V35T, E36A, T39E, S48T, K122E, D123N, K173A, D177E, T200A, Q207A, R211K, V245Q  
ANG6 ANG6 NRTI NNRTI   K32R, V35T, T39E, K122E, D123S, I142V, A158S, D177E, I178M, T200A, Q207R, R211T, F214L, V245Q, E248D, D250E  
ANG60 ANG60 NRTI NNRTI   K20R, V35T, E40D, V60I, K122E, D123G, S162A, K173E, Q174K, D177E, T200A, Q207E, R211N, V245Q, D250E, S251N  
ANG61 ANG61 NRTI NNRTI M184V K101E, E138A, G190A K11S, V35T, T39N, V60I, V75L, K122E, D123S, K173T, Q174R, D177E, I178V, V179I, T200A, I202V, Q207D, R211K, V245Q, S251N  
ANG62 ANG62 NRTI NNRTI   K32I, V35T, T39K, K122E, D123S, S162A, K173A, D177G, T200A, Q207A, R211K, V245Q, E248D  
ANG63 ANG63 NRTI NNRTI   K20R, K32I, V35T, T39K, S134R, K173S, Q174K, D177E, T200A, Q207A, R211S, F214L, V245Q, D250E  
ANG64 ANG64 NRTI NNRTI   V35T, E36M, T39E, S48T, K122E, D123N, I135M, S162A, K173A, D177E, T200A, E203D, Q207G, R211K, V245Q, D250E  
ANG65 ANG65 NRTI NNRTI   K20R, V35T, E40D, K49R, V60I, K122E, D123S, S162R, K173A, D177E, I178M, T200A, Q207T, R211K, V245Q, E248D  
ANG66 ANG66 NRTI NNRTI   V35T, E36D, T39D, K49R, V60I, I135V, S162A, E169D, K173A, Q174K, D177E, I178M, T200A, Q207E, V245Q, E248D, S251C  
ANG67 ANG67 NRTI NNRTI  K101E, E138A, G190A K11S, V35T, T39N, K49R, V60I, K122E, S162G, E169D, K173A, Q174K, D177E, I178V, V179I, T200A, I202V, Q207E, V245Q, S251N D123R 
ANG69 ANG69 NRTI NNRTI M184V K101E, K103N, E138A, G190A K11T, V35T, T39N, V60I, K122E, D123G, K173T, Q174R, D177E, I178V, V179I, T200A, I202V, Q207D, R211K, V245Q, S251N  
ANG7 ANG7 NRTI NNRTI   V35T, K49R, E169D, Q174K, D177E, I178M, Q207E, R211K, V245Q, E248D, D250E  
ANG70 ANG70 NRTI NNRTI M184V, T215F K103N, M230L K20R, V35T, K49R, T69A, K102Q, K122E, D123N, K173T, D177E, T200A, Q207N, R211K, L228Q, V245K  
ANG71 ANG71 NRTI NNRTI   K11T, T27S, V35T, T39R, K43Q, K102Q, D121Y, K122E, D123G, S162C, D177E, I178M, T200A, Q207N, R211K, P243A, I244V, V245K, D250E, S251N  
ANG72 ANG72 NRTI NNRTI   T7S, V8*, K11T, V35T, T39M, S48T, D121H, K122E, A158S, T165I, K173T, Q174K, D177E, G196E, T200A, Q207E, W212R, V245Q, D250E, S251D T107I, I202K, L205V, I244E 
ANG73 ANG73 NRTI NNRTI   K32I, V35T, T39K, K122E, K173A, Q174K, D177E, T200A, Q207A, R211S, F214L, V245E, D250E, S251H  
ANG74 ANG74 NRTI NNRTI  V106I, E138A V35T, T39N, E40D, K49R, V60I, V90I, K122E, D123G, S162D, K173A, Q174K, V179I, Q207D, R211K, V245Q  
ANG75 ANG75 NRTI NNRTI  K103N E6D, K11T, T27S, V35T, T39R, K43Q, D121Y, K122E, D123E, I135T, S162C, D177E, Q197K, T200A, Q207T, I244V, V245K, D250E, S251D  
ANG76 ANG76 NRTI NNRTI   V35K, V60I, D121H, K122E, I142V, K173T, Q174K, D177E, T200A, Q207E, R211K, V245Q, D250E, S251D  
ANG77 ANG77 NRTI NNRTI   V35T, T39M, K49R, K122E, D123N, I135L, S162C, K173I, Q174K, T200A, Q207E, R211K, V245Q, E248N  
ANG78 ANG78 NRTI NNRTI   K20R, V35T, T39K, K43E, K49R, V60I, K102Q, D121H, K122E, D123S, I135T, T139V, Q174H, D177E, T200A, Q207A, R211K, I244V, V245K, D250E  
ANG79 ANG79 NRTI NNRTI   V35T, E36A, T39E, S48T, K122E, D123T, I142V, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, E248D  
ANG8 ANG8 NRTI NNRTI   V35R, E36A, T39E, S48T, D121H, I142V, K173A, D177E, I178L, T200A, Q207E, R211K, F214L, P243A, V245Q  
ANG80 ANG80 NRTI NNRTI M184V K103N K20R, V35T, V60I, I135V, K173I, Q174K, I178M, T200E, Q207K, R211A, V245Q, E248D  
ANG81 ANG81 NRTI NNRTI   I5V, E6D, V35T, T39K, K122E, D123G, A158S, S163T, K173A, D177E, Q207A, R211S, K238R, V245Q, E248D  
ANG82 ANG82 NRTI NNRTI   V35T, E36A, T39E, S48T, K122E, D123N, K173A, Q174K, D177E, I195L, T200A, Q207E, R211K, V245Q, D250E  
ANG83 ANG83 NRTI NNRTI   V35T, E36A, T39E, S48T, K122E, D123N, K173T, D177E, T200A, Q207D, R211K, V245Q  
ANG84 ANG84 NRTI NNRTI   V35T, G45R, V60I, S68G, K104N, K122E, G141E, W153*, A158S, S163T, T165I, E169D, K173A, Q174K, D177E, I178M, G190R, G196R, T200A, R206K, Q207N, R211K, W229*, E233K, V245Q, E248D, D250E L74F, L92F 
ANG85 ANG85 NRTI NNRTI   E6D, V35T, E40D, E53D, K122E, D123N, K173A, Q174K, D177E, T200A, E203D, Q207E, V245Q, E248D, D250E  
ANG86 ANG86 NRTI NNRTI   P14A, V35T, K49R, D86E, S162C, T165I, F171Y, K173T, Q174K, D177E, I178M, T200A, Q207A, R211E, V245Q, E248D, D250E  
ANG87 ANG87 NRTI NNRTI   S3T, T27A, V35P, T39E, E40D, S48T, V60I, V118I, K122E, D123N, K173A, D177E, T200A, Q207K, R211T, F214L, V245Q, P247A K13T, P52L 
ANG88 ANG88 NRTI NNRTI   V35T, V60I, K122P, S162C, Q174R, D177E, I178M, Q207E, R211K, V245Q, E248D  
ANG9 ANG9 NRTI NNRTI   K13N, V35T, K49R, V60I, T69S, T107S, K122E, D123N, K173T, D177E, T200A, Q207E, I244L, V245Q  
ANG90 ANG90 NRTI NNRTI   V35P, T39E, E53D, V60I, T107S, D121Y, K122E, T165I, D177E, G196E, T200A, Q207D, R211K, V241I, I244V, V245K  
ANG91 ANG91 NRTI NNRTI   E6N, K11S, T27P, V35T, T39N, E40D, V60I, K102Q, K104R, K122E, D123N, K173A, Q174K, D177E, T200A, Q207A, R211K, V245Q, E248D  
ANG93 ANG93 NRTI NNRTI  M230I T27P, K32Q, V35T, T39N, E40D, V60I, K173T, D177E, T200A, Q207E, R211K, W229*, V245Q, E248D  
ANG94 ANG94 NRTI NNRTI   P14A, V35T, D86E, K104N, A158S, S162C, F171Y, K173T, Q174K, D177E, I178M, T200A, Q207A, R211E, V245Q, E248D, D250E  
ANG99 ANG99 NRTI NNRTI   P14T, K20R, V35T, E36A, T39E, S48T, K102Q, K122E, D123N, I135V, S162C, K173A, D177E, Q197K, T200A, Q207E, R211K, V245Q  

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Team