Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Haddad (2013)
Title Combinations of HIV-1 reverse transcriptase mutations L100I+K103N/S and L100I+K103R+V179D reduce susceptibility to rilpivirine.
Citation Interscience Conference on Antimicrobial Agents an
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Lab
NumIsolates 8
Lab Parent Strain NL43

 

Lab RT Isolates : Susceptibility Data


IsolateNRTIDRMsNNRTIDRMsMethodDrugFold Res.
201306-1  L100I, K103N PhenoSense DLV >800 
     PhenoSense EFV >1,500 
     PhenoSense ETR 8.2 
     PhenoSense NVP 51 
     PhenoSense RPV 14 
201306-2  L100I, V179D PhenoSense DLV >800 
     PhenoSense EFV >1,500 
     PhenoSense ETR 20 
     PhenoSense NVP 26 
     PhenoSense RPV 6.8 
201306-3  L100I, K103S PhenoSense DLV >800 
     PhenoSense EFV >1,500 
     PhenoSense ETR 6.5 
     PhenoSense NVP 21 
     PhenoSense RPV 17 
201306-4  L100I PhenoSense DLV 23 
     PhenoSense EFV 9.3 
     PhenoSense ETR 1.0 
     PhenoSense NVP 1.3 
     PhenoSense RPV 1.0 
201306-5   PhenoSense DLV 0.9 
    PhenoSense EFV 1.2 
    PhenoSense ETR 1.0 
    PhenoSense NVP 1.0 
    PhenoSense RPV 1.1 
201306-6  V179D PhenoSense DLV 31 
     PhenoSense EFV 14 
     PhenoSense ETR 3.1 
     PhenoSense NVP 16 
     PhenoSense RPV 2.8 
201306-7  K103S PhenoSense DLV 15 
     PhenoSense EFV 6.8 
     PhenoSense ETR 1.1 
     PhenoSense NVP 35 
     PhenoSense RPV 1.2 
201306-8  L100I PhenoSense DLV 37 
     PhenoSense EFV 6.8 
     PhenoSense ETR 1.3 
     PhenoSense NVP 2.1 
     PhenoSense RPV 0.7 

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