Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Porter (2014)
Title Characterization of HIV-1 drug resistance development through week 48 in antiretroviral naive subjects on rilpivirine/emtricitabine/tenofovir DF or efavirenz/emtricitabine/tenofovir DF in the STaR study (GS-US-264-0110)
Citation JAIDS
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 35
NumPts 17
Subtype B

 

Clinical PR Isolates


SubjectIsolatePIsWksPIMajorPIMinorCommonUnusual
STaR1 STaR1_B None  L90M K20T I13V, L19I, E35G, M36I, R41K, R57G, I62V, L63T, I64V, I72T, T74S, V77I  
  STaR1_WK12 None  L90M K20T I13V, L19T, E35G, M36I, R41K, R57G, I62V, L63T, I64V, I72T, T74S, V77I  
  STaR1_WK24 None  L90M K20T I13V, L19IT, E35G, M36I, R41K, R57G, I62V, L63T, I64V, I72T, T74S, V77I  
STaR10 STaR10_B None    E35D, N37S, R57K, I62IV, L63P  
  STaR10_WK24 None    E35D, N37S, R57K, I62V, L63P  
STaR11 STaR11_B None    I13V, R57G, L63D, I64V, E65D, K70R, I72T  
  STaR11_WK12 None    I13V, R57G, L63D, I64V, E65D, K70KR, I72T  
STaR12 STaR12_B None    E35D, N37S, R41K, R57G, I62IV, L63A, I72IV  
  STaR12_WK40 None    E35ED, N37CS, R41K, R57G, I62IV, L63A, I72IV  
STaR13 STaR13_B None    I13V, I15L, L33V, N37S, R41K, K45KR, R57K, L63X, I64V  
  STar13_WK8 None    Q7QR, I13V, I15L, L33V, N37S, R41K, K45KR, R57K, L63X, I64V  
STaR14 STaR14_B None    K14R, Q18E, E35D, M36I, R57G, I62V, L63P, I72V, I93L  
  STaR14_WK21 None    K14R, Q18E, E35D, M36I, R57G, I62V, L63P, I72V, I93L  
STaR15 STaR15_B None    E35D, M36I, N37D, R57K, D60DE, I62V, L63P, V77I, I93L  
  STaR15_WK48 None    E35D, M36I, N37D, R57K, D60E, I62V, L63P, V77I, I93L  
STaR16 STaR16_B None    R57G, L63AT, E65D, I72V, V77I  
  STaR16_WK48 None    R57G, L63A, E65D, I72V, V77I  
STaR17 STaR17_B None    N37T, R57K, I62V, L63ST, A71T, I72V, V77I, I93L  
  STaR17_WK48 None    N37T, R57K, I62V, L63ST, A71T, I72V, V77I, I93L  
STaR2 STaR2_B None    G16E, M36MI, P39S, R41K, R57G, L63T, A71V, I93L  
  STaR2_WK8 None    G16E, P39S, R41K, R57G, L63AT, A71V, I93L  
STaR3 STaR3_B None    T12PS, I13V, L19LI, N37A, R57G, L63P, I64V  
  STaR3_WK24 None    T12S, I13V, N37A, R57G, L63P, I64V  
STaR4 STaR4_B None    T12TP, I13IV, K14KR, N37S, R57K, L63P, I64V, C67X  
  STaR4_WK16 None    T12P, K14R, R57K, L63P, I64V, C67D  
STaR5 STaR5_B None    T12P, N37S, R57G, L63A, I72V, V77I, I93L  
  STaR5_WK16 None    T4TA, T12P, N37S, R57G, L63A, I72V, V77I, I93L  
STaR6 STaR6_B None   L10LF K14KR, E35D, R41RK, R57RG, L63P  
  STaR6_WK40 None    E35D, R57G, L63P  
STaR7 STaR7_B None    T12S, L19I, E35D, R57K, L63P, H69Q, A71AT  
  STaR7_WK16 None    T12S, L19I, E35D, R57K, L63P, H69Q  
STaR8 STaR8_B None    T12TA, I13V, G17E, K20I, M36I, R41K, R57G, L63P, H69K, K70KR, I72L, L89I  
  STaR8_WK12 None    T12A, I13V, G17E, K20I, M36I, R41K, R57G, L63P, H69K, K70R, I72L, L89I  
STaR9 STaR9_B None    R57G, L63P, I72E, V77I, I93L  
  STaR9_WK37 None    R57G, L63P, I72E, V77I, I93L  

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