Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Brockman (2012)
Title Uncommon pathways of immune escape attenuate HIV-1 integrase replication capacity.
Citation J Virol
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 88
NumPts 88
Subtype B

 

Clinical IN Isolates


SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
AEHIV1 AEHIV1 None    E11D, E13D, V31I, S57N, I60V, S119P, T122I, S195T, V201I, S230N, D256E  
AEHIV10 AEHIV10 None    E11D, N27G, V31I, V32VI, L101I, S119G, T122I, T124A, G193E, V201I, D278S  
AEHIV11 AEHIV11 None    E10D, E35Q, S39N, L45V, L101I, S119G, T122I, K136T  
AEHIV12 AEHIV12 None    K111T, T124A, D256E  
AEHIV13 AEHIV13 None    E11D, E13D, V31I, S57N, I60V, I72V, L74I, I89M, S119P, T122I, T124A, S195T, V201I, I203IM, S283SG  
AEHIV14 AEHIV14 None    I72V, K111Q, T112V, I113V, T124N, K211R, S283G  
AEHIV15 AEHIV15 None    S17C, I72V, T125A, R231K  
AEHIV16 AEHIV16 None    E11D, E13D, V31I, S57N, I60V, S119P, T122I, T124N, S195T, V201I, D286N  
AEHIV17 AEHIV17 None    I72V, T124A, A265V  
AEHIV18 AEHIV18 None    L101I, S119G, T122I, V201I, C280S  
AEHIV19 AEHIV19 None    E11D, S17N, L28I, V31I, S39C, M50I, I60V, I72V, A91G, L101I, K156N, V165I, S230N  
AEHIV2 AEHIV2 None    L74V, L101I, K111Q, T112I, T125A, D167E, K173R, I208L  
AEHIV20 AEHIV20 None    P90S, L101I, T124A, I220L  
AEHIV21 AEHIV21 None    E11D, A23V, N27G, V31I, L101I, S119G, T122I, T124A, G193E, V201I, I203M, D278S  
AEHIV22 AEHIV22 None    E11D, L101I, S119A, T124Q, G193E, S283G, D288N  
AEHIV23 AEHIV23 None    E10A, K14R, R20K, S39C, M50I, G193E, V201I, D232E  
AEHIV24 AEHIV24 None    E10V, S119P, T122I, T124N, T125A, I135V, G163E, I182V, D256E  
AEHIV25 AEHIV25 None    K7R, K111T, V201I, I208L, E212A, D232E  
AEHIV26 AEHIV26 None    K7R, E11D, S24N, V31I, L101I, K111T, T122I, I135V, V281M  
AEHIV27 AEHIV27 None    I72V, I113V, T124A, T125M, M154MI, V201I  
AEHIV28 AEHIV28 None    K7R, E11D, V31I, L101I, K111T, T122I, V281M, D286N  
AEHIV29 AEHIV29 None    K7R, V31I, L101I, G163E, T206S, D232E  
AEHIV3 AEHIV3 None    R20K, T124A, G193E, I208L, N254Q, S255G, D288N  
AEHIV30 AEHIV30 None    R20K, I72V, K111R, M154L, T210I, K211R, D256E  
AEHIV31 AEHIV31 None    V31I, I72V, P90S, L101I, K111Q, T124A, I135V, F181L, I203M  
AEHIV32 AEHIV32 None    E11D, S17T, M22I, A23V, V31I, V37I, M50I, L101I, G163E, D167E, V201I, T206S  
AEHIV33 AEHIV33 None    D6DE, E11ED, S17N, L45LV, M50MT, I72IV, T124TA, T125TA, V126VL, I135IV, G163GE  
AEHIV34 AEHIV34 None    D6E, E11D, S17N, A21S, A23V, L28I, V37I, S39C, M50I, T124A, V201I  
AEHIV35 AEHIV35 None    T206S, D207E  
AEHIV36 AEHIV36 None    T112V, I135V, F181L, V201I, T206S, D256E, I268L, D270H, R284G  
AEHIV37 AEHIV37 None    S17N, I72V, T112I, I113V, T124A, T125A, T206S  
AEHIV38 AEHIV38 None    D6DE, E11D, K14R, S17SN, I60V, I72V, I113IV, S123SC, T124N, T125TA, V126VL, D256E  
AEHIV39 AEHIV39 None    E11D, L101I, K111T, T112A, S119P, T124N, T125A, I135V, G193R, T218S, V260I I161IS 
AEHIV4 AEHIV4 None    L101I, S119T, T124Q, T125M, G193E, S283G, D288N  
AEHIV40 AEHIV40 None    E11D, K14R, N18D, R20K, A21T, V37I, L101I, S119SG, T122I, T124A, T125A, D167E, S195C, E198D, Y227F, D253H, D278A, S283G  
AEHIV41 AEHIV41 None    S17N, V31I, L101I, K136N, V151VI, G163E, K188R, S230N, S283G  
AEHIV42 AEHIV42 None    K14R, S17N, K34KR, L101I, T124A, T125A, K156N, D167E, V201I, I208L, S230N, N254K  
AEHIV43 AEHIV43 None    V31I, V88I, K111T, S119T, T124A, T125A, I203M, S230N  
AEHIV44 AEHIV44 None    K7R, S17N, I72V, T124A, V201I, E212K, S230N, D253E, A265V  
AEHIV45 AEHIV45 None    S17N, I72V, T125I, K156N, E287K  
AEHIV46 AEHIV46 None    E11D, S24N, K173R, V176L  
AEHIV47 AEHIV47 None    K14R, S24SN, V32I, L101I, T112A, I135IV, T218S  
AEHIV48 AEHIV48 None    E11D, S24G, L45I, L101I, S119G, T122I, I220L, A265V  
AEHIV49 AEHIV49 None    E11D, S17C, I72V, L101I, S119P, T122I, T206S  
AEHIV5 AEHIV5 None    L101I, T124N, G193GE, I200L, V201I, Q216H, N222H, S230N, R231K, K240R, V281M  
AEHIV50 AEHIV50 None    E11D, A21T, S119P, T124N, V176L, T206S  
AEHIV51 AEHIV51 None    E11D, S24N, L101I, T112V, I113V, D232E, A265V  
AEHIV52 AEHIV52 None    E11D, V31I, T112V, K136Q, R187K, V201I, T218S, I220L, S230N, V259I, R269K  
AEHIV53 AEHIV53 None    L45V, I72V, V88I, L101I, I113V, S119P, T125A, G163E, S195C, V201I, V250VL, D256E, D270E  
AEHIV54 AEHIV54 None    E11D, L101I, K111T, S119T, V151I  
AEHIV55 AEHIV55 None    E13G, L45I, L101V, K156N, A265V  
AEHIV56 AEHIV56 None    L45I, M154I, V201I  
AEHIV57 AEHIV57 None    E11D, V31I, D41DN, L101I, G163E  
AEHIV58 AEHIV58 None    E11D, K111T, S119P  
AEHIV59 AEHIV59 None    E11D, I72V, V88I, L101I, I113V, S119P, G163E, S195C, V201I  
AEHIV6 AEHIV6 None   A128T S24G, L45V, T112I, K156N  
AEHIV60 AEHIV60 None    E11D, V31I, L101I, G106A, K111T, T122I, G193E, V201I, D286N N222HY 
AEHIV61 AEHIV61 None    E11D, V32I, I72V, V88I, L101I, G163E, S195C, V201I, K240R  
AEHIV62 AEHIV62 None    K14R, L101I, K103R, T122I, V201I, A265V  
AEHIV63 AEHIV63 None    E11D, S24N, I72V, T122I, T124N, T206S, I208L  
AEHIV64 AEHIV64 None    E11D, V32I, I72V, K111T, T112A, S119T, S230N, D286DN  
AEHIV65 AEHIV65 None    R20K, L45LI, I72IV, L101I, K156N, D256E  
AEHIV66 AEHIV66 None    E11ED, V31I, L101I, K111T, S119P, V126VA, V201VI, A265V  
AEHIV67 AEHIV67 None    L45I, L101I, A265V  
AEHIV68 AEHIV68 None    S17N, L101I, A265V  
AEHIV69 AEHIV69 None    E11D, R20K, S24N, I72V, K111T, T112A, S119T, S230N  
AEHIV7 AEHIV7 None    E11D, N27G, L45I, S119P, T124A, G193E, V201I, E212A, L234I, D256E, D279G  
AEHIV70 AEHIV70 None    L101I, G193E, E212A  
AEHIV71 AEHIV71 None    E11D, S24N, H51R, L101I, T124H  
AEHIV72 AEHIV72 None    E10D, S39C, I72V, T112I, T122I, T124N, T125V, K211R  
AEHIV73 AEHIV73 None    D6DE, E11D, V31I, V37VI, M50I, I72V, L101I, K111T, S119P, T122I, K211R  
AEHIV74 AEHIV74 None    E11D, V31I, M50I, I72V, L101I, K111T, S119P, K211R  
AEHIV75 AEHIV75 None    E11D, S24N, V31I, L101I, K111T, T112A, S119T, I135V, T218S, S283G  
AEHIV76 AEHIV76 None    K7KR, E11D, D25E, S39C, L45V, L101LI, T112A, S119P, T122I, T125A, I204IV, E212A, Q216H, K219N, D286N  
AEHIV77 AEHIV77 None    E11D, K111T, S119P  
AEHIV78 AEHIV78 None    E11D, L101I, T122I, G193E  
AEHIV79 AEHIV79 None    E11D, S24D, L28I, V37I, S39C, L101I, T124A, V201I  
AEHIV8 AEHIV8 None    V31I, I60M, I72V, V79A, S119P, V201I, T206S, K219N, D288N  
AEHIV80 AEHIV80 None    E11D, S17C, V31I, L101I, M154MI, K188R  
AEHIV81 AEHIV81 None    V32I, D41DN, L45I, L101I, S119T, K160T, V201I, I217V, S230N, L234I, D253E  
AEHIV82 AEHIV82 None    V31I, L101I, G193E, V260I  
AEHIV83 AEHIV83 None    L101I, A265V  
AEHIV84 AEHIV84 None    E11D, L101I, A265AV  
AEHIV85 AEHIV85 None    E11D, M50I, L68AV, I72IV, L101I, K111T, V176L, V201I  
AEHIV86 AEHIV86 None    E11D, V31I, M50I, L101I, K111T, S119P, T122I  
AEHIV87 AEHIV87 None    E10D, V31I, V54I, I72V, T112I, I113V, T124N, T125V, K211R, T218I  
AEHIV88 AEHIV88 None    S39M, I72V, S119P, T122I, K156N, V201I, T206S, K219N, L234I  
AEHIV9 AEHIV9 None    L101I, T124A, A175T, G193E, V201I, I220L  

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