Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Coetzer (2013)
Title Extensive drug resistance in HIV-infected Cambodian children who are undetected as failing first-Line antiretroviral therapy by WHO 2010 guidelines.
Citation ARHR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 58
NumPts 51
Subtype CRF01_AE, B

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
KH001 KH001 3TC, D4T NVP M184V A98G, K101E, Y181C, H221Y V35T, T39K, K43E, K64R, K122E, D123N, K173I, Q174K, D177E, I178M, Q207A, R211S  
KH002 KH002 3TC, D4T NVP M184V, T215F V108I, Y181C V35T, T39K, K43E, K49KR, K102Q, K122E, D123S, K166R, K173I, Q174K, D177E, I178IM, T200I, Q207A, R211RS, L228R, K238R  
KH003 KH003 3TC, D4T NVP D67DN, M184V A98G, Y181C V35T, T39K, K43E, K122E, D123S, K173T, Q174K, D177E, T200A, E203EK, Q207A, R211S, F214FL, K238R  
KH004 KH004 3TC, D4T NVP D67N, M184V K103N, E138Q, K238T V35T, T39K, K43E, V60I, K122E, D123S, I135T, S162C, K173I, Q174K, D177E, V179VI, T200A, Q207A, R211S  
KH005 KH005 3TC, D4T NVP V75M, M184V K101E, G190A V35T, T39N, K122E, D123S, I135IT, K166R, K173T, Q174R, D177E, I178M, G196R, T200A, Q207A, R211S, L228LR  
KH006 KH006 3TC, D4T NVP M184V K101E, Y181C E28K, K32E, V35T, T39N, K49R, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, G196E, Q207G, R211S, F214L  
KH007 KH007 3TC, D4T NVP M184V K103N, V108I V35T, T39K, E40K, K43E, K46Q, K122E, D123N, I135T, I142V, S162A, K173T, Q174K, D177E, I178M, T200A, E204D, Q207A, R211S, F214L  
KH008 KH008 3TC, D4T NVP L74LI, M184V Y181C, H221Y V35T, T39K, K43E, V75VL, D121H, K122E, D123S, I135T, K173I, Q174K, D177E, T200I, Q207A, R211S, F214FL, K238R  
KH009 KH009 3TC, D4T NVP A62V, D67N, V75I, F77L, F116Y, Q151M, M184V K101E, G190A E28K, V35T, T39K, K43E, K122E, D123S, S162A, Q174E, D177E, I178M, E204K, Q207A, R211S  
KH010 KH010 3TC, D4T NVP D67N, K70R, M184V, T215F, K219E A98G, V108I, Y181C V35T, T39K, K43E, T69N, K122E, D123S, K173A, Q174K, D177E, T200A, Q207A, R211RS, L228H  
KH011 KH011.1 3TC, D4T NVP M41L, D67N, V75M, M184V, L210W, T215Y V106I, G190A V35T, T39N, E44D, K101A, L109LI, V118I, K122E, D123S, S162C, K173R, Q174K, D177E, I178M, V179I, Q207A, R211NS, K238R  
  KH011.2 3TC, D4T NVP M41L, D67N, V75M, M184V, L210W, T215Y V106I, Y181C, G190A V35T, T39N, K43Q, E44D, K101A, V118I, K122E, D123NS, S162D, K173R, Q174K, D177E, I178M, V179I, Q207A, R211N, K238R  
KH012 KH012 3TC, D4T NVP A62V, V75I, F116FY, Q151M, M184V E138G, G190A I31L, V35K, T39E, S68G, K122E, K173I, Q174K, I178M, V179I, T200I, Q207A, R211S, K238R  
KH013 KH013 3TC, D4T NVP D67N, V75M, M184V, L210W, T215F K101E, G190S V35T, K64Y, V118I, K122E, D123S, K173I, Q174K, D177E, I178M, V179VI, T200A, E203D, Q207A, R211NS  
KH014 KH014 3TC, D4T NVP D67N, V75M, F77FL, F116Y, Q151M, M184V Y181C V35T, T39K, K122E, D123S, A158T, K173T, Q174K, D177E, T200A, I202V, Q207E, R211K, K238R  
KH015 KH015 3TC, D4T NVP A62V, D67E, M184I, L210W, T215F Y181C I31L, V35T, T39K, K43E, V90I, V111I, D121H, K122E, T128X, K173I, Q174K, D177E, I178L, V179I, Q207A, R211N, L228H  
KH016 KH016 3TC, D4T NVP D67N, M184V, T215Y K101E, E138EQ, G190A E28K, K32Q, V35T, T39K, K43E, E44D, K64R, V118I, K122E, D123G, S162C, K173R, Q174K, N175Y, Q207A, L210S, R211N  
KH017 KH017 3TC, D4T NVP M41L, K65R, K70T, V75M, M184V V106I, Y181C, H221Y V35T, E36A, I37F, T39E, S68G, T107S, K122E, D123N, S162C, K173I, Q174K, T200I, Q207A, R211S, F214L, K238R  
KH018 KH018 3TC, D4T NVP V75VI, F116Y, Q151M, M184V K103N, E138Q A33AV, V35T, T39TK, S68G, K122E, D123S, S162C, K173I, Q174K, D177E, Q207A, R211S  
KH019 KH019 3TC, D4T NVP K65R, F116Y, Q151M K103N, Y181C, H221Y A33V, V35T, T39K, K43E, V60I, S68G, K102KQ, K122E, D123DN, S163C, R172K, K173I, Q174K, D177E, I178L, T200R, Q207A, H208Y, R211S, K238R  
KH020 KH020 3TC, D4T NVP M41ML, M184V, T215TI V106I, Y181YC, G190GA, H221HY V35T, T39KN, K122E, D123NS, I132IL, I135T, S162SC, K173AV, Q174K, D177E, T200TA, Q207S, R211S, F214FL, K238R  
KH021 KH021 3TC, D4T NVP V75M, M184V K103N, V106I, V108I, H221Y V35T, T39M, K49R, K122E, D123S, I135T, S162C, K173I, Q174K, D177E, I178M, V179IT, Q207S, R211S  
KH022 KH022.1 3TC, D4T NVP A62V, V75I, M184V Y181C I31L, V35T, T69TA, K101KQ, K102KR, K122E, D123S, K166KR, K173A, Q174K, D177E, V179M, Q207E, D218E, K238R  
  KH022.2 3TC, D4T NVP A62V, V75I, M184V Y181C I31L, V35T, T69TA, K101KQ, K102KR, K122E, D123S, K166R, K173A, Q174K, D177E, V179M, Q207E, D218E, K238R  
KH023 KH023 3TC, D4T NVP K70KR, M184V K103N, Y181C V35T, K49KR, T69N, K122E, D123N, I135V, K173I, Q174K, D177E, I178L, Q207D, R211K, F214FL, L228LH  
KH024 KH024.1 3TC, D4T NVP K65R, D67N, T69D Y181C, G190A V35T, T39K, K43E, K122E, D123S, P157PA, K173I, Q174K, D177E, I178M, V179I, Q207A, R211S, K238KR  
  KH024.2 3TC, D4T NVP D67H, K70R, L74I, M184V, T215I, K219E Y181C, G190A V35T, T39K, K43E, T69N, K122E, D123S, I135T, K173I, Q174K, D177E, V179I, Q207A, R211S, K238R  
KH025 KH025 3TC, D4T NVP V75I, M184I V108I, Y181C V35T, T39K, K43E, V60I, K122E, D123S, I135T, K173I, Q174K, D177E, Q207A, R211S, K238R  
KH026 KH026.1 3TC, D4T NVP M41L, M184V, T215F V108I, Y181C V35T, T39K, K43E, K122E, D123N, I135T, K173L, Q174K, D177E, V179I, Q207A, R211S, K238R  
  KH026.2 3TC, D4T NVP M184V, T215F V108I, Y181C V35T, T39K, K43E, A98AS, K122E, D123N, I135T, K173L, Q174K, D177E, V179I, Q207A, R211S, K238R  
KH027 KH027 3TC, D4T NVP M41ML, V75I, M184V G190A, H221Y V35T, T39K, K43E, V60I, K122E, D123N, I132L, I135T, S162A, Q174E, D177E, V179I, Q207A  
KH028 KH028 3TC, D4T NVP D67DN, M184IV Y181C V35T, T39N, V90I, K122E, D123N, I135M, T165L, K173I, Q174K, D177E, I178M, Q207E, R211S  
KH029 KH029 3TC, D4T NVP M184V, T215Y V106VI, Y181C I31L, V35T, T39K, K122E, D123S, K173I, Q174K, D177E, I178M, Q207S, R211S P225F 
KH030 KH030.1 3TC, D4T NVP M41L, D67N, M184V, T215Y V106I, V108VI, Y181V, H221Y V35T, T39K, K43E, K122E, D123S, S162C, K173AT, Q174K, D177E, Q207A, R211S, K238R  
  KH030.2 3TC, D4T NVP D67N, M184V V106I, Y181V, H221HY V35T, T39K, K43E, K122E, D123S, S162C, Q174K, D177E, Q207A, R211S, K238R  
KH031 KH031 3TC, D4T NVP M184V K103N, V106I, H221Y, M230L V35T, T39E, D121H, K122E, D123S, I135L, S162C, K173I, Q174K, D177E, Q207A, R211S, K238R  
KH032 KH032 3TC, D4T NVP K65N, V75M, M184V, K219R V108I, Y181C V35T, E36K, T39K, K43E, A62T, S68G, K122E, D123N, I135V, A158T, T165I, K173T, Q174K, D177E, I178M, T200A, Q207A, R211S, F214L  
KH033 KH033 3TC, D4T NVP D67DN, M184V, T215TI Y181C V35T, T39K, K43E, K122E, D123S, I135IT, T139R, K173R, Q174K, D177E, V179I, T200I, Q207A, R211S, K238R  
KH034 KH034 3TC, D4T NVP D67DN, M184V G190A V35T, T39K, K43E, V60I, K101Q, K102Q, K122E, D123S, K166KR, K173I, Q174K, D177E, I178M, V179I, T200A, Q207A, R211S L26L* 
KH035 KH035.1 3TC, D4T NVP V75M, M184V V108I, Y181C V35T, E36KQ, T39K, K43E, K122E, D123N, I142T, K173IT, Q174K, D177E, I178M, Q207A, R211S, L228R, K238R  
  KH035.2 3TC, D4T NVP V75M, M184V V108I, Y181C V35T, E36KQ, T39K, K43E, K122E, D123N, I142IT, K173IT, Q174K, D177E, I178M, Q207A, R211S, L228R, K238R  
KH036 KH036 3TC, D4T NVP D67G, M184V Y181C, G190A I31L, V35T, T39K, K122E, D123S, K173M, Q174K, D177E, I178M, Q207A, R211N, K238R  
KH037 KH037 3TC, D4T NVP K65R V106I, Y181C, H221HY V35T, K101Q, K122E, D123S, A158T, S162C, K173M, Q174K, D177E, Q207A, R211S, K238R  
KH038 KH038 3TC, D4T NVP K65KR K103KN, Y181YC I31IL, V35T, T39EK, K122E, D123S, K166KR, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R  
KH039 KH039 3TC, D4T NVP M184V, T215FS Y181C I31L, V35T, T39K, K43E, K49KR, K122E, D123S, E169D, K173R, Q174K, D177E, I178L, V189VI, Q207A, R211S, K238R  
KH040 KH040 3TC, D4T NVP M184V K101E, G190A V35T, T39K, K43E, K122E, D123N, K173I, Q174K, D177E, T200A, Q207A, R211S, K238R  
KH041 KH041 3TC, D4T NVP M184V A98G, Y181C V35T, T39N, K122E, D123N, I135IT, K173I, Q174K, D177E, T200MR, Q207A, R211S, F214L, K238R  
KH042 KH042 3TC, D4T NVP M184V V108I, Y181C, H221Y V35T, T39E, K122E, D123S, K173I, Q174K, D177E, G196E, T200R, Q207A, K238R  
KH043 KH043 3TC, D4T NVP A62V, M184V G190A V35T, T39E, K122E, D123N, I135T, K173R, Q174K, D177E, I178M, T200I, E203K, Q207D, K238R  
KH044 KH044 3TC, D4T NVP M184V V108I, Y181C V35T, T39E, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, Q207A, R211S  
KH045 KH045.1 3TC, D4T NVP M184V K101E, Y181C E28A, V35T, T39E, K122E, D123N, I135T, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R  
  KH045.2 3TC, D4T NVP M184V K101KE, Y181C E28A, V35T, T39E, K122E, D123N, I135T, K173I, Q174K, D177E, I178M, Q207A, R211S, K238R  
KH046 KH046 3TC, D4T NVP M184V V106I, Y181C V35T, T39K, K43E, K122E, D123N, I135T, K173I, Q174K, D177E, Q207A, R211S  
KH047 KH047 3TC, D4T NVP K65N, V75M, M184V Y181C I31L, V35T, T39E, S68R, K122E, D123S, I132L, I135T, K173I, Q174K, D177E, I178M, V179I, T200A, Q207A, R211S, K238R K64Q 
KH048 KH048 3TC, D4T NVP M184V Y181C V35T, T39K, K43E, K49R, K101R, K102Q, K122E, D123N, T139I, K173T, Q174K, D177E, I178M, V179I, T200A, Q207G, R211S, K238R  
KH049 KH049 3TC, D4T NVP M184MV K103KN V35T, T39KN, K43KE, K122E, D123NS, I135IT, K173I, Q174K, D177E, I178M, T200A, Q207A, R211RS  
KH050 KH050 3TC, D4T NVP  V106I V35T, T39R, V60I, K122E, D123N, I135T, G196E, Q207H, R211K  
KH051 KH051 3TC, D4T NVP   V35T, T39K, K43E, K122E, D123N, S162C, K173I, Q174K, D177E, I178M, T200A, Q207S, R211S