Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Wang (2009)
Title Protective HLA class I alleles that restrict acute-phase CD8+ T-cell responses are associated with viral escape mutations located in highly conserved regions of human immunodeficiency virus type 1.
Citation J Virol
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 91
NumPts 91
Subtype B


Clinical PR Isolates

01144G 01144G None    L10I, L63T, I93L  
012286G 012286G None      
014837G 014837G None    G17E, I62V, L63S, E65D  
1229I 1229I None    L63P, H69Q, V77I  
AT01480 AT01480 None  V82A, I84V, L90M L10F, L33F I13V, E35D, M36I, N37D, D60E, I62V, L63P, A71V, I72V, P79S  
CR0017Q CR0017Q None  I54V, I84V L24I L10I, T12P, K14R, A22V, E35D, M36I, N37D, R57K, I62V, L63P, A71V, Q92K  
CR0023W CR0023W None    I15V  
CR0027M CR0027M None  M46L, I54V, V82A, I84V  L10V, I13V, E35D, M36I, L63P, A71V, I72V  
CR0036W CR0036W None    M36I, R41K, L63Q, I64V  
CR0047U CR0047U None    I64V, E65D, V77I  
CR0050Z CR0050Z None   Q58E E35D, R41K, D60E, Q61E, L63P, I93L  
CR0058S CR0058S None    L63T  
CR0059T CR0059T None    L10I, L63S, I93L  
CR0068P CR0068P None    I13V, L63P  
CR0078 CR0078 None    L19I, R57K, L63P, C67S  
CR0080N CR0080N None    I15V, E35D, M36I, I62V, L63P, I93L  
CR0116Y CR0116Y None    I13V, G16E, E35D, N37S, L63S, I64V, V77I  
CR0127W CR0127W None    E35D, N37S, K45R, L63S, I64V, V77I  
CR0131 CR0131 None    I64V, K70R  
CR0154X CR0154X None    K20R, L63P, I64V, A71T  
CR0164U CR0164U None    K14R, L33V, E35D, N37S, R41K, I64V  
CR0175S CR0175S None    L10I, I15V, R57K, D60E, L63T, E65D, I93L  
CR0192W CR0192W None    N37C, I62M, L63P, A71T, I93L  
CR0206U CR0206U None    L10I, I15L, I62V, L63P, I93L  
CR0208W CR0208W None    T12N, L63P, H69Q, V77I  
CR0214 CR0214 None    I15V, L19I, N37A, L63P, I64L, H69Q  
CR0215 CR0215 None    R41K, Q61E, I64V  
CR0222X CR0222X None      
CR0228Q CR0228Q None    K14R, I15V, L19T, M36I, N37D, K55R, L63P  
CR0234 CR0234 None    T12N, L63P, V77I, I93L  
CR0248X CR0248X None    R57K, Q61E, L63P, I64L, I72V, I93L  
CR0275 CR0275 None    I13V, L63P  
CR0276Z CR0276Z None  M46I, I54L, I84V, L90M L10F, L33F T4P, I13V, F53Y, Q61H, L63P, H69Q, A71V, V77I, I93M  
CR0289Z CR0289Z None    K14R, I15V, N37D, I64V, V77I, I93L  
CR0295S CR0295S None    L10I, L33V, N37S, P39S, R41K, L63P, I64V, I93L  
CR0307R CR0307R None  M46I  M36I, N37D, L63P, I93L  
CR0312W CR0312W None  M46I, G48V, I54S, V82A  L10I, I15V, R41K, I62V, L63Q, A71V, T74S, I93L  
CR0317N CR0317N None    R41K, L63P  
CR0331P CR0331P None    L10I, M36I, L63T, C67Y, I93L  
CR0339X CR0339X None  L90M  M36I, N37T, R57K, I62V, L63P  
CR0345Q CR0345Q None    I15V, G16E, E35D, P39T, D60E, L63P  
CR0361T CR0361T None    K14R, N37D, L63P, C67D, K70R, V77I  
CR0367Z CR0367Z None    L10I, E35D, R57K, L63P, I93L  
CR0382N CR0382N None    E35D, N37D, R57K, A71V, I72E, V77I, I93L  
CR0413T CR0413T None  M46I  I15V, M36I, G49E, L63S  
F701 F701 None    L19T, E35D, N37S, I62V, L63A, V77I  
F706 F706 None    T12A  
F710 F710 None    E35D, N37D, K70R, V77I  
F714 F714 None    L63P, A71T, V77I, I93L  
F7157 F7157 None    K14R, I15V, N37S, R57K, I62V, L63A, I64M  
F7165 F7165 None    E35D, N37S, R57K, L63P  
F7172 F7172 None    K14R, I15V, N37D, I64V, V77I, I93L  
F719 F719 None    T12N, I15V, L19I, L63P  
F762P F762P None    L33I, N37S, R41K, D60E, I64V, I93L  
F781 F781 None      
F797 F797 None  M46L, I84V, L90M L33F I13V, L19I, K20R, E35D, M36I, L89F  
L805 L805 None    G16E, E35D, P39S, D60E, I62V, L63P  
L8107 L8107 None    I15V, G16E, N37E, P39S, L63P, V77I  
L8116 L8116 None    L10V, T12P, I13V, L63Q, I64V  
L8124P L8124P None    E35D, N37D, L63P  
L8152 L8152 None    E35D, M36I, R57K, L63T, I64V, E65D, I72T  
L8180 L8180 None    L19I, N37S, L63V, H69Q, V77I  
L8188 L8188 None    L33V, N37A, L63Q, I64V  
L819 L819 None    I13V, M36I, N37D, I64V  
L8249 L8249 None    M36I, N37D, I62V, L63S, I64V  
L827 L827 None    I15V, L19T, E35D, N37S, R41K, I62V, L63P, A71T, I93L  
L861P L861P None    K14R, Q18L, E35D, N37D, L63P  
L893P L893P None    I13V, K20M, I64V  
L896 L896 None    L19I  
MTF MTF None    E35D, N37D, L63P, A71T, I72E  
NCQ NCQ None    E35D, N37T, P39Q, I62V, L63P, A71V, V77I, I93L  
PRLS01 PRLS01 None    L33V, R41K, L63P  
PRLS02 PRLS02 None    K14Q, I15V, L19I, L63P  
PRLS04 PRLS04 None    T12A, I13V, K14R, N37E, L63P, V77I  
PRLS05 PRLS05 None    I13V, G16A, E35D, N37S, L63P  
PRLS08 PRLS08 None  D30N N88D E35D, M36I, K45R, R57K, L63P, H69Q, A71T  
PRLS09 PRLS09 None    I13V, E35D, M36I, N37D, L63A, I72V  
PRLS12 PRLS12 None    E35D, L63P, V77I  
PRLS16 PRLS16 None  M46I, I54V, V82A L24I, L33F L10I, K20M, E35D, M36I, R41K, I62V, L63P, I72V  
PRLS17 PRLS17 None    R41K  
PRLS18 PRLS18 None    L10V, T12P, I13V, L63Q, I64V  
PRLS19 PRLS19 None    L33I, N37S, R41K, D60E, L63P, C67S  
PRLS24 PRLS24 None    L10V, I15V, R41K, L63A, I72T, I93L G16W 
PRLS25 PRLS25 None    L19T, E35D, N37S, L63A, V77I  
PRLS28 PRLS28 None    L63S  
SH8127 SH8127 None    R41K, L63P, I64V, V77I, I93L  
SH8183 SH8183 None    T12P, L19I, M36L, N37S, L63P, A71V, V77I, I93L  
SH8229 SH8229 None    R57K, Q61E, L63P, E65D, V77I  
SH8233 SH8233 None    T12P, K14R, G16E, N37S, P39S, I62V, L63P, H69Q, V77I, I93L  
SH8241 SH8241 None    I15V, R41K  
SH858 SH858 None    I64V