Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Wang (2009)
Title Protective HLA class I alleles that restrict acute-phase CD8+ T-cell responses are associated with viral escape mutations located in highly conserved regions of human immunodeficiency virus type 1.
Citation J Virol
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 91
NumPts 91
Subtype B


Clinical IN Isolates

01144G 01144G None    R20K, L28I, T112A, S283G  
012286G 012286G None    A49P, I72V, I113V, T124A, T206S, L234I  
014837G 014837G None    A23V, S39C, M50I, I72V, L101I, T124A, K136N, F181L, Q216H, L234I, D288N  
1229I 1229I None    V31I, I60M, L101I, D207N, K219E, N222K, A265V  
AT01480 AT01480 None    D6E, E10D, K34R, S119R, R231K  
CR0017Q CR0017Q None    E11D, R20K, V31I, A38S, S39C, A91E, L101I, T112A, S119R, V201I, N254Q, R284G  
CR0023W CR0023W None    D3E, D55N, T124N, G163N, V201I, T206S, K211R, K219Q, I220L, I251V  
CR0027M CR0027M None    L28I, P30A, S39C, L101I, S119T, K188R, V201I, T206S, Y227F, L234V, A265V  
CR0036W CR0036W None    V31I, I72V, S119P, T122I, K211R, A265V  
CR0047U CR0047U None    L45Q, I72V, P90S, V201I, K219N, N222K, S230N  
CR0050Z CR0050Z None    E11D, K14R, S24N, I72V, P90S, S119P, T122I, T125A, V126M, V201I, T206S, D256E  
CR0058S CR0058S None    E11D, S24N, M50I, I72V, I84V, V201I, T206S, I208L, D256E  
CR0059T CR0059T None    K111R  
CR0068P CR0068P None    S17N, S39C, L45V, M50I, I72V, T112V, I113V, T124A, T125A, K211R, D253E, N254G, S283G  
CR0078 CR0078 None    E11D, S57G, L101I, S119G, T122I, V201I, Q216H  
CR0080N CR0080N None    N27S, V31I, L45Q, L101I, S119G, T122I, T125A, K211R  
CR0116Y CR0116Y None    E11D, S17T, V37I, A91T, L101I, S119R, T124S, T125A, K160T  
CR0127W CR0127W None    E11D, K14R, A23V, L28I, V37I, S39C, I60M, I113V, S119P, A169V, V201I  
CR0131 CR0131 None    M50I, I72V, T124A, G193D, V201I, I217V, N254Q, S255G  
CR0154X CR0154X None    E11D, S24N, L101I, T112A, S119G, T122I, T125A, K173R, F181L, V201I  
CR0164U CR0164U None    E11D, S17T, M22I, L28M, V32I, S39R, I72V, L74I, I89L, S119G, T124N, K173R, V176L, D256E  
CR0175S CR0175S None    I72V, G163Q, A248S  
CR0192W CR0192W None    E11D, L74I, S119P, F121S, A265V  
CR0206U CR0206U None    L28I, P30A, L101I, T112A  
CR0208W CR0208W None    S39C, M50I, I72V, L101I, I113V, V201I, I220V, L234I, K240R  
CR0214 CR0214 None    E10D, I60M, I72V, V79I, D256E, D270N, R284G, D288N  
CR0215 CR0215 None    D25E, I113V, T125A, T206S, T210I, S230N, R231K  
CR0222X CR0222X None    S17N, V31I, V32I, L45I, I60V, L101I, I203M, D256E  
CR0228Q CR0228Q None    K7R, S17N, L28I, L45V, I72V, L101I, K111R, T124A, K160N, V165I, I208L, T218S, S283G  
CR0234 CR0234 None    L28I, S39C, I72V, I84M, L101I, T125A, I200M, V201I, I203M, T206S, I208L P30T 
CR0248X CR0248X None    S17N, D25E, L101I, G106A, K111R, T112R, T124G, K160Q, I208L, D256E, D278A, S283G, R284G  
CR0275 CR0275 None    K7R, V31I, L101I, K111T, T206S, D232E  
CR0276Z CR0276Z None    M22I, I73V, L74I, Y99L, I113V, T125A, K211R, D256E  
CR0289Z CR0289Z None    S17N, A23V, L28I, S39C, I72V, I113V, T124A, E152K, F181L, V201I, T206S, Q216H G190E 
CR0295S CR0295S None    E11D, V31I, T206S, S283G  
CR0307R CR0307R None    G4E, D6N, E35K, D55N, K71Q, L101I, I113V, S119R, T125A, G134R, E157K, E170K, G193E, V201I, K219N, N222K, S283G G149R 
CR0312W CR0312W None    K7R, I72V, K156N, R187K, V201I, I220L  
CR0317N CR0317N None    G106A, T112V, I113V, T124A, T206S, D207E, I208L, I217S, N254Q, S255G  
CR0331P CR0331P None    R20K, V151I, K188R, S283G  
CR0339X CR0339X None    I72V, L101I, I182V, G193E, V201I, T206S, T218S, D286N  
CR0345Q CR0345Q None    S39C, A49P, I72V, T112A, T124A, T125A, R187K  
CR0361T CR0361T None    K7R, E11D, S17N, L28I, I72V, L101I, S119G, T122I, K173R, G193E, I220L  
CR0367Z CR0367Z None    E11D, R20K, L28I, T112A, S283G  
CR0382N CR0382N None    M50I, V54I, L101I, K136T, V150A, V201I  
CR0413T CR0413T None    K14R, D41N, V79I, L101I, K111Q, T112V, E157K, E170K, K173R, D278G  
F701 F701 None    E11D, M50I, I60V, I113V, S119T, T206S, I208L, D232E, D256E  
F706 F706 None    S24G, D41N, I72V, M154I  
F710 F710 None    E10D, M50I, I72V, S119P, T124N, T125A, V126L, G163Q, T206S, I208L, L234I, D253E, D256E  
F714 F714 None    V31I, I72V, E152K, V201I, A265V  
F7157 F7157 None    E10A, E11D, S17N, S24D, D25E, S39C, I182V, V201I  
F7165 F7165 None    S24N, V31I, T112A, T124A, T125A, T218I, A265V  
F7172 F7172 None    S17N, A23V, L28I, S39C, I72V, I113V, T124A, F181L, V201I  
F719 F719 None    K14R, S24G, D25E, L28I, S39C, I72V, L101I, T124N, K173R, I182V, T206S  
F762P F762P None    D3E, V151I  
F781 F781 None    I72V, I113V, V151I, L234V  
F797 F797 None    E11D, K14R, R20K, I60V, I72V, P90S, T124A, G193E, V201I, L234V, D286N  
L805 L805 None    E11D, A21T, V31I, I72V, L101I, I113V, S119P  
L8107 L8107 None    E11D, A21T, V31I, I72V, I113V, T124A, I203M, I204V, I220L  
L8116 L8116 None    K14R, M22L, L28I, V37I, S39C, L101I, G193E, K211R, D286N  
L8124P L8124P None    I72V, L101I, T112I, S119P, T122I, T124N, T125A, M154L, D167E, V201I, T206S, I208M, D256E  
L8152 L8152 None    E11D, L101I, K111N, S119T, V201I, T206S, D256E, M275V  
L8180 L8180 None    R20K, M50I, I72V, P90S, L101I, V201I, N254H, A265V  
L8188 L8188 None    D6E, E10D, S39C, L45Q, I72V, V201I, T218S, L234H, D253E  
L819 L819 None    I182V, S230N, R231K, R284G  
L8249 L8249 None    M50I, T124N, T125A, V176L  
L827 L827 None   G163R E10D, I72V, T125A, M154I, K156N, V201I, D256E  
L861P L861P None  E138K  E11D, S24N, I72T, I113V, S119P, T122I, T125A, K156N, A196P, V201I, A205S  
L893P L893P None    T124A, S230N, R231K  
L896 L896 None    S17N, I72V, I113V, T124N, T125A, S230N, A265V  
MTF MTF None    G4R, E11D, S24N, V31I, G82R, I89V, K111Q, I113V, S119T, V151I, K156N, V201I, T218S, D256E Q148P 
NCQ NCQ None    V31I, L101I, A133T, V201I, T206S, I217V, A265V, R269K, S283G  
PRLS01 PRLS01 None    S17N, I72V, L101I, K111R, S119P, T124A, T125A, M154I, K211Q, T218I, D232E, D256E  
PRLS02 PRLS02 None    K14R, S24G, D25E, L28I, S39C, I72V, L101I, T124N, K173R, I182V, T206S  
PRLS04 PRLS04 None    E11D, K14R, A21T, V31I, I72V, I113V, T125A, I203M, T218S, I220L  
PRLS05 PRLS05 None    E11D, S17T, V31I, I72V, A91T, L101I, K111T, S119P, T122I, T125A, D167E  
PRLS08 PRLS08 None   E157Q L45Q, I72V, K111R, K160T, D256E  
PRLS09 PRLS09 None    E11D, S24N, M50I, V201I, K211R  
PRLS12 PRLS12 None    D6E, E11D, A21T, I72V, I84V, S119P, T124N, T125A, V126L, M154I  
PRLS16 PRLS16 None    E11D, E13D, R20K, V31I, L101I, K111T, S119P, T122I, K160R, V201I, S230N, D256E  
PRLS17 PRLS17 None    Q62R, I84V, T122I, T125A, M154I, K211R, K219N, N222K  
PRLS18 PRLS18 None    K14R, M22L, L28I, V37I, S39C, L101I, G193E, K211R, D286N  
PRLS19 PRLS19 None    S17N, I72V, T112A, T124A, T125V, K156N  
PRLS24 PRLS24 None    S39C, L101I, T124A, G193E, D279G  
PRLS25 PRLS25 None    E11D, M50I, I60V, I113V, S119T, T206S, I208L, T210A, D232E, D256E  
PRLS28 PRLS28 None    D25E, I72V, T124N, M154L  
SH8127 SH8127 None    I72V, I113V, S119P, T124A, V201I, T206S, K211R, E212L, K215N, S230N, M275V, S283G  
SH8183 SH8183 None    E10A, E11D, A21T, I84V, T112R, S119P, T122I, T125A, M154I, L234I  
SH8229 SH8229 None    L101I, T125A, G193E, V201I, I220L, Y227F, D232E, L234V, D279G  
SH8233 SH8233 None    E11D, P30S, V31I, I60V, L101I, V201I, I203M  
SH8241 SH8241 None    E11D, S24G, L45V, M50I, I72V, T218S, D253E, D256E  
SH858 SH858 None    I72V, P90S, T124A, V201I, S230N, R231K