Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Miura (2008)
Title Genetic characterization of human immunodeficiency virus type 1 in elite controllers: Lack of gross genetic defects or common amino acid changes.
Citation J Virol
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 41
NumPts 41
Subtype B


Clinical RT Isolates

SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
BEC1 BEC1 None None   E169D, Q207E, V245K, K277R, L283I, I293V, I326V, T377R, V381I, T403I, V435I, R463K, H483HQ  
BEC106 BEC106 None None   E6D, T200I, E203D, V245M, E248D, K277R, I293V, R307K, V317A, S322T, K366R, V372I, E449D, V458I, S468P, V548I  
BEC108 BEC108 None None   K122E, I135V, R211K, V245E, K277R, I293V, D324E, M357T, S379G, K390R, T403I, S468P, K527N, E546K  
BEC110 BEC110 None None   I135IT, S162SN, I178L, T200I, R206K, V245X, D250E, S251H, A272T, K277R, I293V, K311KR, F346Y, A376T, K390R, A400T, R461K  
BEC111 BEC111 None None   D123E, I135T, K166KR, D177E, I178V, V245MT, K277R, I293V, Q334L, R358K, K390R, T403V, V435I, L452LI, S468P, Q480QH, A554T  
BEC112 BEC112 None None   K64R, I142V, I159V, K166R, Q174H, D250E, S251C, A272P, K277R, Q278H, T286A, I293V, G333E, Q334L, M357T, V365I, K366KR, T369A, A376T, A400T, V435I, K465R, K512R, A554T, K558R  
BEC113 BEC113 None None   V35I, R83K, I135T, R172RK, D177G, R211E, A272P, K277R, R284K, E297K, Q334E, G335N, R356K, A376T, A400T, D460N  
BEC117 BEC117 None None   E6D, K20R, K166R, D177E, Q207E, R211K, A272P, I293V, E297K, K311R, G333E, P345T, A360T, T377M, S379C, T386I, A400T, T403A, D460N, R461K, V467I, T470A, L491V, I506L, S519N  
BEC119 BEC119 None None   R83K, G196E, K277R, Q278H, T286A, A288G, E297K, K311R, G333E, Q334H, T338S, D364E, T377K, V417I, D460N, R463RK, K465R, V467I, S519N I309IT 
BEC121 BEC121 None None   E6K, E40D, E42EK, A98S, D123E, S162C, Q207E, R211K, A272P, K277R, I293V, E297K, K311N, Q334L, K390R, A400T, E404D, V417I, V435I, D460N, G490GE, L491S, K527R, A554T P321E 
BEC125 BEC125 None None   R83K, A98S, K122P, I135R, I142N, D177E, T200K, F214L, K223Q, K277R, T286A, E291D, E297R, L301I, I329L, M357T, A376T, E399D, A400T, D460N, S468P, L491S, L517I, K527Q, E529D, A554T  
BEC13 BEC13 None None   R83K, D123E, I135V, I178M, A272P, K281R, T286A, E297K, K385R, A400T, V435I, D460N, R463RK, H483HY, L491S, A554T  
BEC24 BEC24 None None   K49R, S162C, N175H, D177E, I178M, P243S, V245E, K281KR, T286A, I293V, Q334D, F346Y, M357T, K390R, E399D, A400T, V435A, D460N, R461RK, S519N, A554N  
BEC33 BEC33 None None   R83K, D123E, Q174QR, T200K, V245M, A371T, A376AT, V417VI, D460N, H483Y, Q509QH, L517X, S519N  
BEC35 BEC35 None None   T69S, A272P, K277R, Q334Y, A376T, K390R, T403I, V417I, R461RK, H483Q, E514D, V548I, I556V, K558R, V559I  
BEC36 BEC36 None None   I50V, F214L, R284RK, A288S, I293V, G335D, R356K, M357T, I375V, T377M, E399D, A400T, T403S, V435I, A446S, L452V, R461K, V466I, H483Y, S519N, V548I, A554K, K558R  
BEC37 BEC37 None None  K101E, E138A K122E, T165I, I195L, S251N, K277R, T286A, A288S, V292I, D324E, I326V, Q334E, M357R, A360T, E396D, V435I, L484I, A554T D123P 
BEC43 BEC43 None None  K103N K102G, K122E, I142V, V245E, E248S, I293V, S322T, D324E, L325LV, G359S, A371V, A376S, V381I, K390R, T403M, Y405H, R448K, L452S, R461K, V467VI, H483Y, L517I, K527N  
BEC45 BEC45 None None   V60I, R83K, I135V, S163T, D177E, I178V, G196E, T200V, R211G, K281R, E297R, V317A, S322T, Q334H, T338S, K366R, T369A, K390R, K431T, V435I, D460N, S468T, L491S, Q509V, A554S  
BEC46 BEC46 None None   V21I, R211K, A272P, V276I, K277R, T286A, E297K, Q334L, R356RK, M357T, R358K, A376T, L452S, D460N, V467I, H483Y, E492D  
BEC48 BEC48 None None   G196E, F214L, D250E, I293V, E297K, L301I, P313R, Q334L, M357T, A400T, E449EK, L452I, D460N, R461K, V548I, K558R  
BEC49 BEC49 None None   V118I, I135V, I142L, Y144F, D177N, I178V, V189I, F214L, L228Q, K277R, T286A, I293V, E297K, G335S, A376T, E399D, V458I, D460N, D471N, K558R  
BEC5 BEC5 None None   I135T, G333E, Q334P, R356K, S379G, N418S, Q509H, L517I, V548I  
BEC50 BEC50 None None  E138K D123E, I142V, S162C, I178L, Q207E, R211K, V245M, I293V, I329L, M357T, T377M, K395R, A400S, Y405H, V435I, V466I, V467I, I521V  
BEC51 BEC51 None None   R83RK, I135V, I195T, T200TA, V245M, V276I, T286A, I293V, K323R, G333D, A360T, K390R, K431KR, D460N, R461K, L491S, E516V  
BEC52 BEC52 None None  V179E R83K, K102R, K122P, D177E, V245K, A272P, K277R, E297R, K311E, H315Y, Q334L, R356K, A376T, T386I, A400T, K431T, R461K, Q464K, V466I, V467I, T470A, L517I, A554T  
BEC53 BEC53 None None   T7P, K11KR, E28K, R83K, K104KR, S162H, R211K, V245M, T286TA, D320DN, Q334D, R356K, A376S, D460N, R461K, L491S, Q520QH, A554S  
BEC57 BEC57 None None  V108I, E138A V35I, K122Q, I135M, V179I, D192E, R211K, A272P, T286A, E297A, R307RK, Q334E, M357R, T369A, S379G, T386I, K390R, A400T, E404D, V435I, L452A, D460N, T470A, L517IV, S519N  
BEC59 BEC59 None None   R83K, T200V, A272P, K281R, E297K, A327AV, I329V, R356RK, A371V, A400T, V435I, D460N, H483Q, A554T  
BEC60 BEC60 None None   R83K, I135T, D250E, A272P, K277R, T286A, F346Y, M357T, A376T, K390R, A400T, K454R, D460N, S468T, H483Q, L491V, Q509H, S519N, A534T, A554N  
BEC62 BEC62 None None   K104R, I135V, I195IL, I244V, V245M, A272P, K277R, I293IV, P294S, A400T, L452I, D460N, S468P, H483HY, S519N, K527KQ  
BEC64 BEC64 None None   V35M, V60I, S68G, K82R, R83K, I135T, R211X, I329L, R358K, A376T, A400T, T450TI, K530R  
BEC65 BEC65 None None   K103R, I135V, I142T, Q174G, I244V, V245K, A272P, K277R, L283LF, T286A, I293V, I326V, Q334Y, R356K, T377M, T403M, F416Y, S468P, L491S, I506L, S519N, A554T, V559I H235R 
BEC66 BEC66 None None   P4PS, G196S, V245K, K277R, T286A, I326V, Q334E, R356K, A376S, A400T, T403S, S468P, T470A, A554T, K558R  
BEC68 BEC68 None None   R83RK, K122P, D177DE, I178ILM, A272P, E297A, K390R, A400T, T403M, V435I, S468P, H483Q, A554T  
BEC7 BEC7 None None   R83K, K122KE, D123DE, I135T, S162C, D250E, A272P, K281R, E297K, S322T, I329L, M357T, K374KR, A376T, A400T, V435I, D460N, V467I, H483Y, Q487L, L503I, S519N  
BEC71 BEC71 None None   E29D, V35M, S48E, K102Q, D123E, I135V, F214FL, V245E, A272P, K281R, E297T, M357T, A371V, A376T, I393M, A400T, E404D, V435I, S468P, L491S, K512KQ, Q520K, A534S, A554S  
BEC77 BEC77 None None   K43R, R83K, D177N, I329L, V365I, K374R, A376T, L452A, D460N, Q480K, E546K, I556V  
BEC78 BEC78 None None   K122KR, V179VI, G196E, Q207E, V245K, V292I, I293V, I309IL, G333E, T377R, S379C, T386I, K388R, E396D, Y405H, V435VA, L452I, R461K, L517LV, A554T, V559I P97PS 
BEC86 BEC86 None None   K49R, R83K, I244V, A272P, P294T, S322A, I329V, M357T, T369V, A371T, A376S, T377L, S379G, T386I, D460N, L491S, K512R  
BEC99 BEC99 None None   I31V, R83K, I202V, V276I, Q278H, A360AT, A376T, T377S, V381I, L452I, R461K, H483Y, I556V, K558R, V559I