Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Villena (2007)
Title Relative fitness and replication capacity of a multinucleoside analogue-resistant clinical human immunodeficiency virus type 1 isolate with a deletion of codon 69 in the reverse transcriptase coding region.
Citation J Virol
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Lab
NumIsolates 2
Lab Parent Strain NL43


Lab RT Isolates : Susceptibility Data

IsolateNRTIDRMsNNRTIDRMsMethodDrugFold Res.
NL43-69d T69~  HeLa-CD4 reporter gene 3TC 5.3 
     HeLa-CD4 reporter gene 3TC 3.5 
     HeLa-CD4 reporter gene ABC 1.3 
     HeLa-CD4 reporter gene AZT 0.2 
     HeLa-CD4 reporter gene D4T 1.0 
     HeLa-CD4 reporter gene DDC 1.3 
     HeLa-CD4 reporter gene DDI 1.0 
     HeLa-CD4 reporter gene DLV 0.6 
     HeLa-CD4 reporter gene EFV 0.5 
     HeLa-CD4 reporter gene NVP 0.5 
     HeLa-CD4 reporter gene TDF 0.7 
NL43-T69A   HeLa-CD4 reporter gene 3TC 1.2 
    HeLa-CD4 reporter gene 3TC 1.1 
    HeLa-CD4 reporter gene ABC 1.0 
    HeLa-CD4 reporter gene AZT 0.7 
    HeLa-CD4 reporter gene D4T 1.1 
    HeLa-CD4 reporter gene DDC 1.1 
    HeLa-CD4 reporter gene DDI 1.1 
    HeLa-CD4 reporter gene DLV 0.8 
    HeLa-CD4 reporter gene EFV 0.7 
    HeLa-CD4 reporter gene NVP 0.8 
    HeLa-CD4 reporter gene TDF 0.8