Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Brehm (2012)
Title Frequent emergence of N348I in HIV-1 subtype C reverse transcriptase with failure of initial therapy reduces susceptibility to reverse-transcriptase inhibitors.
Citation Clin Infect Dis
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 138
NumPts 63
Subtype C

 

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Page 1   listing Isolate 1 to Isolate 100 from Total 138 Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
01ZA 01ZA.0 None None   P4ST, K20R, V35T, E36A, T39E, S48T, V60I, K122E, D123G, K166KR, K173A, D177E, T200A, Q207E, V245K, A272P, K275R, K277G, E291D, V292I, I293V, Q334H, G335D, R356K, M357R, G359T, T377M, K390R, A400T, E404D, I434M, V435A, A437V, L452I, S468T, D471E, H483QR, L491S, I506L, K512R, L517I, S519SN, Q524E, K530R, A534T, A554S  
  01ZA.60 3TC, D4T EFV  K103N E6K, K20R, V35T, E36A, T39E, S48T, V60I, K122E, D123G, K173A, D177E, T200A, Q207E, V245K, A272P, K275R, K277G, E291D, V292I, I293V, Q334H, G335D, R356K, M357R, G359T, T377M, K390R, A400T, E404D, I434M, V435A, A437V, L452I, S468T, D471E, H483R, L491S, I506L, K512R, L517I, S519N, Q524E, K530R, A534T, A554S  
02ZA 02ZA.0 None None   V35T, E36A, T39E, E40D, K43R, S48T, K122E, D123X, K173A, D177E, G196K, T200A, Q207E, R211K, V245Q, A272Q, K277KR, T286A, E291D, V292I, I293V, K311R, E312X, Q334H, G335D, R356K, G359T, K366R, Q373QH, T377M, K390R, A400T, E404D, V435A, L452T, R461K, V466I, S468T, T470N, D471E, T477A, H483Q, L491S, S519N, K527N, K530R, V531I, A534S, V548I, A554NS  
  02ZA.84 3TC, D4T EFV   V35T, E36A, T39E, E40D, K43R, S48T, K122E, D123X, K173A, D177E, G196K, T200A, Q207E, R211K, V245Q, A272Q, K277KR, T286A, E291D, V292I, I293V, K311R, E312X, Q334H, G335D, R356K, G359T, K366R, T377M, K390R, A400T, E404D, V435A, L452T, R461K, V466I, S468T, T470N, D471E, T477A, H483Q, L491S, S519N, K527N, K530R, V531I, A534S, V548I, A554NS  
03ZA 03ZA.0 None None   E6D, V35T, E36A, T39E, S48T, K122E, D123N, T139A, A158S, K173T, Q174K, T200A, Q207E, R211K, V245Q, A272P, L279M, T286A, E291D, V292I, I293V, Q334H, G335D, R356K, G359T, T377L, K390R, A400T, E404D, V435A, L452M, R461K, V466I, S468T, D471E, T477A, H483Q, L491S, S519N, K527N, K530R, V531I, A534S, A554N  
  03ZA.72 3TC, D4T NVP   E6D, V35T, E36A, T39E, E40ED, S48T, K122E, D123N, T139A, A158S, K173IT, Q174K, T200A, Q207E, R211RK, V245Q, A272P, K277KR, Q278QH, L279LM, T286A, E291D, V292I, I293IV, Q334H, G335D, R356K, G359T, T377L, K390R, A400T, E404D, V435A, L452M, R461RK, V466I, S468PT, D471E, T477A, H483Q, L491S, L517LI, S519N, K527N, K530R, V531I, A534S, A554N  
04ZA 04ZA.0 None None   V35T, E36EA, T39E, S48T, K122E, I135T, S162C, K173A, D177E, T200A, Q207E, R211K, D250E, S251D, A272P, T286A, E291D, V292I, I293V, Q334E, G335D, R356K, M357R, G359T, A360T, T369TA, T377LQ, S379CG, K390R, A400T, E404D, V435L, K451R, L452X, D471E, H483Q, L491S, E516G, S519N, K527N, K530R, A534S, A554S  
  04ZA.48 3TC, D4T EFV M184V  V35T, T39E, S48T, K122E, I135T, S162C, K173A, D177E, T200A, Q207E, R211K, D250E, S251D, A272P, T286A, E291D, V292I, I293V, Q334E, G335D, R356K, M357R, G359T, A360T, T377Q, S379C, K390R, A400T, E404D, V435L, K451R, L452V, V467I, D471E, H483Q, L491S, S519N, K527N, K530R, A534S, A554S  
  04ZA.96 3TC, D4T EFV M184V K103N, N348I V35T, T39E, S48T, K122E, D123DG, I135T, S162SC, K173A, D177E, T200A, E203EK, Q207E, R211K, D250E, S251D, A272P, T286A, E291D, V292I, I293V, Q334E, G335D, R356K, M357R, G359T, A360T, E370EG, T377Q, S379C, K390R, A400T, E404DN, V435L, K451R, L452V, V467I, D471E, H483Q, L491S, S519N, K527N, K530R, A534S, A554S  
05ZA 05ZA.0 None None   V35T, T39E, S48T, K122E, D123G, S162SG, E169D, K173A, D177E, T200A, Q207D, R211K, V245Q, A272PS, K277KR, Q278QH, T286TA, E291D, V292I, I293V, V317VA, G335D, R356K, M357KR, G359T, K366R, T377L, I380V, K390R, A400I, E404D, I434L, V435I, A437V, L452I, S468T, D471E, H483Q, L491S, K512N, S519N, K527Q, K530R, A534S, A554S  
  05ZA.84 3TC, D4T EFV M184V  V35T, T39E, S48T, K122E, D123G, S162X, E169EAD, K173AE, D177E, T200A, Q207D, R211RK, V245Q, A272P, I274IV, Q278HY, E291D, V292I, I293V, G335D, R356K, M357KR, G359T, K366R, T377L, I380V, K388KR, K390R, E399ED, A400I, E404D, I434L, V435I, A437V, L452I, S468T, D471E, H483Q, L491S, K512N, S519N, K527Q, K530R, A534S, A554S  
06ZA 06ZA.0 None None   V35T, E36A, T39E, S48T, E53D, D123E, K166R, K173AT, Q174QK, D177E, I178IM, T200A, Q207E, V245Q, E248ED, A272P, K275R, V276I, K277R, T286A, E291D, V292I, I293V, Q334H, G335D, R356K, G359S, T369A, Q373H, T377Q, K390R, A400T, E404D, L452M, R463RK, V466I, L469M, D471E, H483Q, L491S, S519N, K530R, A534S, A554N  
  06ZA.72 3TC, D4T NVP M184MV K103KN, N348NI V35T, E36A, T39E, S48T, E53D, D123E, K166KR, K173A, Q174K, D177E, T200A, Q207E, V245Q, L246LM, E248ED, A272P, K275R, V276I, K277R, T286A, E291D, V292I, I293V, Q334H, G335D, R356K, G359S, T369A, Q373H, T377Q, K390R, A400T, E404D, L452M, R463RK, V466I, L469M, D471E, H483Q, L491S, S519N, K530R, A534S, A554N  
  06ZA.84 3TC, D4T NVP M184V K103N, G190GA, N348NI V35T, E36A, T39E, S48T, E53D, D123E, K173A, Q174K, D177E, T200A, Q207E, V245Q, A272P, K275R, V276I, K277R, T286A, E291D, V292I, I293V, Q334H, G335D, R356K, G359S, T369AV, Q373H, T377Q, K390R, A400T, E404D, L452M, R463K, V466I, L469M, D471E, H483Q, L491S, S519N, K530R, A534S, A554N  
07ZA 07ZA.0 None None  K103N V35T, T39A, S48T, K64R, K122E, S162C, K173A, N175H, D177E, T200A, K201T, Q207E, R211K, V245Q, A272P, K277R, T286AV, E291D, V292I, I293V, E344D, R356K, G359T, A376G, T377LM, K390R, A400I, E404D, V435A, A437V, L452I, V458VA, V466I, S468H, D471E, H483Q, L491S, S519N, Q520E, E529D, A534S, A554S  
  07ZA.48 3TC, D4T EFV M184V K103N, P225H V35T, T39A, S48T, K64R, K122E, S162C, K173A, N175H, D177E, T200A, K201T, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, E344D, R356K, G359T, A376G, T377L, K390R, A400I, E404N, V435A, A437V, L452I, V466I, S468H, D471E, H483Q, L491S, S519N, Q520E, E529D, A534S, A554N  
08ZA 08ZA.0 None None   K11T, T27S, V35T, S48T, K122E, D123DG, K173A, Q174K, D177E, T200E, Q207N, R211K, V245K, A272P, L283I, E291D, V292I, I293V, K311R, Q334DN, G335D, R356K, M357R, G359S, T377LS, K390R, E404D, E413D, V417VI, V435AT, A437V, A446S, E449D, L452I, D471E, H483Q, L491P, S519N, K527R, K530R, A534S, A554N I329IMV 
  08ZA.60 3TC, D4T EFV   K11T, T27S, V35T, S48T, K122E, D123DG, K173A, Q174K, D177E, T200E, Q207N, R211K, V245K, A272P, L283I, E291D, V292I, I293V, K311R, I329V, Q334N, G335D, R356K, M357R, G359S, T377S, K390R, E404D, E413D, V417VI, V435A, A437V, A446S, E449D, L452I, D471E, H483Q, L491P, L517LI, S519N, I522IV, K527R, K530R, A534S, A554N  
09ZA 09ZA.0 None None  K103KN, Y181YC, G190GA K20KR, V35T, E36EA, T39E, S48T, V60I, K122E, D123N, T165TI, K173A, Q174K, D177E, T200A, Q207AT, R211K, F214FL, V245Q, A272P, E291D, V292I, I293V, Q334D, G335D, R356K, M357R, G359T, T377Q, S379C, K390R, A400I, E404D, V435A, N447NS, L452M, V466I, L469Q, T470S, D471E, H483L, L484I, L491S, S519N, K530R, A534S, A554S  
  09ZA.24 3TC, D4T EFV M184V K103N I31L, V35T, T39E, S48T, V60I, V90I, K122E, D123N, K173A, Q174K, D177E, T200A, I202V, Q207T, R211K, V245Q, A272P, E291D, V292I, I293V, Q334D, G335D, R356K, M357R, G359T, T377Q, S379C, K390R, A400I, E404D, V435A, L452M, V466I, L469Q, T470S, D471E, H483L, L484I, L491S, S519N, K530R, A534S, A554S  
  09ZA.36 3TC, D4T EFV M184V K101KE, K103N, N348NI E28EK, V35T, T39EG, S48T, V60I, V90I, K122E, D123N, I135IL, K173A, Q174K, D177E, T200A, I202V, Q207T, R211K, V245Q, A272P, E291D, V292I, I293V, P294PS, Q334D, G335D, R356K, M357R, G359T, T377Q, S379C, K390R, A400I, E404D, V435A, L452M, V466I, L469Q, T470S, D471E, H483L, L484I, L491S, S519N, K530R, A534S, A554S  
10ZA 10ZA.0 None None   V35T, E36EA, T39E, S48T, K122E, D123S, K173T, Q174K, I178L, E194EA, T200A, Q207KN, R211K, V245Q, E248ED, A272P, K277R, Q278H, T286A, E291D, V292I, I293V, I329L, Q334D, G335GD, R356K, G359T, T377M, K390R, A400T, E404D, V435L, A446S, L452AT, S468HP, D471E, T477S, H483Q, L491P, S519N, K527KR, K530R, A534S, A554S  
  10ZA.48 3TC, D4T EFV  K103N V35T, T39E, S48T, K122E, D123S, K173T, Q174K, I178L, E194T, T200E, Q207A, R211K, V245Q, E248D, A272P, K277R, Q278H, T286A, E291D, V292I, I293V, I329L, Q334D, R356K, G359T, T377M, K390R, E404D, V435L, A446S, L452A, S468T, D471E, T477S, H483Q, L491P, S519N, K530R, V531I, A534S, A554S  
11ZA 11ZA.0 None None   V35T, T39E, S48T, K122E, K173A, D177E, T200A, I202V, E204D, Q207X, R211T, V245Q, A272P, K277R, E291D, V292I, I293V, S322T, I329L, Q334D, G335D, R356K, M357R, G359T, T377M, K390R, A400T, E404D, V435A, A437V, E449D, V466I, V467I, L469I, D471E, H483Q, L491P, S519N, Q524E, K530R, A534S, A554S  
  11ZA.96 3TC, D4T NVP  V106VA, Y188YC V35T, T39E, S48T, K122E, K173A, D177E, T200A, I202IV, E204DN, Q207AE, R211KT, V245Q, A272P, K277R, E291D, V292I, I293V, S322T, I329L, Q334D, G335D, R356K, M357R, G359T, T377M, K390R, A400T, E404D, V435A, A437V, E449D, V466I, V467I, L469I, D471E, H483Q, L491P, S519N, Q524E, K530R, A534S, A554S  
  11ZA.144 3TC, D4T NVP M184V Y181C, N348I V35T, T39K, S48T, K122E, I135IT, K166R, K173A, Q174K, D177E, T200A, I202V, E204D, Q207E, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, S322T, I329L, Q334D, G335D, R356K, M357R, G359T, T377M, K390R, A400T, E404DN, V435A, A437V, E449D, V466I, V467I, L469I, D471E, H483Q, L491P, S519N, Q524E, K530R, A534S, A554S  
12ZA 12ZA.0 None None   K11KQ, V35T, E36A, T39E, K122E, D123N, K173T, Q174K, D177E, I178M, T200A, Q207E, R211RK, V245N, A272P, E291D, V292I, I293IV, D324E, Q334DE, G335D, R356K, M357R, G359T, K366R, A376S, T377M, K385R, K390R, T403V, E404D, I434L, V435A, A437V, L452I, V467I, S468T, L469I, T470N, D471E, H483Q, L491S, S519N, K530R, A534S, A554S  
  12ZA.60 3TC, D4T NVP M184MIV Y181C, N348NI I31IL, V35T, E36A, T39E, K122E, D123N, K173T, Q174K, D177E, T200A, Q207E, V245N, A272P, E291D, V292I, I293V, D324E, Q334E, G335D, R356K, M357R, G359T, K366R, A376S, T377M, K385R, K390R, T403I, E404D, I434L, V435A, A437V, L452I, V467I, S468T, L469I, T470N, D471E, H483Q, L491S, S519N, K530R, A534S, A554S  
13ZA 13ZA.0 None None   V35T, T39E, S48T, K122E, D123N, A158S, T165I, K173A, D177E, I178V, T200A, I202IV, E204EK, Q207AD, R211K, V245Q, T286A, E291D, V292I, I293V, Q334E, G335D, R356K, M357R, R358RK, G359T, V365VI, T369A, K385KR, K390R, A400I, E404D, V435A, A437V, E449D, L452M, S468T, D471E, H483Q, L491LS, A508AG, L517I, S519N, I526V, K530R, A534S, A554S  
  13ZA.48 3TC, D4T NVP M184V Y181C V35T, T39E, S48T, K122E, D123N, A158S, T165L, K173A, D177E, I178V, T200A, E204K, Q207E, R211K, D218E, L228LR, V245Q, T286A, E291D, V292I, I293V, Q334E, G335D, R356K, M357R, G359T, V365I, T369A, K390R, A400I, E404D, V435A, A437V, E449D, L452M, S468T, D471E, H483Q, L491S, L517I, S519N, I526V, K530R, A534S, A554S  
14ZA 14ZA.0 None None   V35T, E36A, T39D, S48T, V60I, K122E, D123N, K173A, D177DE, Q197QL, T200A, Q207E, R211K, V245E, K277R, Q278QE, T286A, E291D, V292I, I293V, Q334H, G335D, R356K, M357R, G359T, T377TM, K390R, A400IT, E404D, L452I, V467I, S468T, T470A, D471E, H483Q, L491S, S519N, Q524E, K530KR, V531VI, A534S, A554K  
  14ZA.48 3TC, D4T EFV  V106M, Y188YC V35T, E36A, T39D, S48T, V60I, K122E, D123N, K173A, D177DE, T200A, Q207E, R211K, V245E, K277R, T286A, E291D, V292I, I293V, Q334H, G335D, R356K, M357R, G359T, T377M, K390R, A400IT, E404D, L452IV, V466VA, V467I, S468T, T470A, D471E, H483Q, L491S, S519N, Q524E, K530KR, A534S, A554K  
15ZA 15ZA.0 None None   K20R, V35T, E36A, T39E, S48T, V60I, K122E, D123N, K173A, D177E, G196E, T200A, Q207E, P243PS, V245K, D250DE, K277R, T286A, E291D, V292I, I293V, Q334N, G335D, R356K, M357MR, G359T, V365VI, A376S, T377M, K390R, E399D, A400IT, E404D, V435VA, L452I, R461K, V466VI, V467VI, S468T, T470N, D471E, T477TA, H483Q, L491S, K530R, A534S, A554N  
  15ZA.36 3TC, D4T EFV   K20R, V35T, E36A, T39E, S48T, V60I, K122E, D123N, K173A, D177E, G196E, T200A, Q207E, V245K, D250E, S251N, K277R, T286A, E291D, V292I, I293V, Q334N, G335D, R356K, G359T, V365I, A376S, T377M, K390R, A400T, E404D, L452I, R461K, V466I, S468T, T470N, D471E, T477A, H483Q, L491S, K530R, A534S, A554N  
16ZA 16ZA.0 None None   E6K, V35T, E36A, T39D, S48T, V60I, A98S, V118C, K122E, D123E, K173A, T200A, I202V, Q207E, R211K, V245Q, A272P, V292I, I293V, K311R, Q334HN, G335D, R356K, M357T, G359T, K366R, T377Q, K390R, A400T, E404D, V435P, L452I, V466I, V467VI, T470TN, D471E, H483Q, L491S, S519N, Q524E, K530R, V531I, A534S, A554R  
  16ZA.48 3TC, D4T EFV  K103KN E6K, V35T, E36A, T39DE, S48T, V60VI, A98S, V118X, K122E, D123E, K173A, D177DE, T200A, I202IV, Q207E, R211RK, V245Q, A272P, K277KR, T286TA, V292I, I293V, K311KR, Q334HN, G335D, R356K, M357MIT, G359T, K366KR, T377Q, K390R, A400T, E404D, V435AP, L452I, K454KR, V466I, D471E, H483Q, L491S, S519N, Q524QE, K530R, V531I, A534S, A554R  
  16ZA.84 3TC, D4T EFV M184V K103N, N348NI E6K, V35T, E36A, T39D, S48T, V60I, A98S, V118C, K122E, D123E, I135IT, T139TK, K173A, T200A, I202V, Q207E, R211K, V245Q, A272P, V292I, I293V, K311R, Q334H, G335D, R356K, M357T, G359T, K366R, T369TI, T377Q, K390R, A400T, E404D, V435P, L452I, V466I, T470N, D471E, H483Q, L491S, S519N, Q524E, K530R, V531I, A534S, A554R  
17ZA 17ZA.0 None None   E6D, V8I, K20R, V21I, V35T, T39E, E40D, K122E, D123N, I135T, I159IV, S162SC, K173T, E194DN, T200A, Q207E, R211K, A272P, L279T, T286A, E291D, V292I, I293V, V317A, I329V, Q334H, G335D, R356K, G359T, T369A, A371T, T377L, K390R, A400T, E404D, V435A, G436GE, N447S, V466I, T470N, D471E, T477A, H483Q, L491S, S519N, K527N, E529D, K530R, V531I, A534S, A554S  
  17ZA.24 3TC, D4T NVP  G190A E6D, V35K, T39E, E40D, K122E, D123N, I135T, S162C, K173T, E194N, T200A, Q207E, R211K, A272P, L279T, T286A, E291D, V292I, I293V, V317A, I329V, Q334H, G335D, R356K, G359T, T369A, A371T, T377L, K390R, A400T, E404D, V435A, G436E, V466I, T470N, D471E, T477A, H483Q, L491S, S519N, K527N, E529D, K530R, V531I, A534S, A554S  
18ZA 18ZA.0 None None   V35T, E36A, T39E, S48T, V60I, K122E, D123G, K173A, Q174K, D177DE, I178L, G196E, T200A, Q207E, V245Q, E248D, A272P, E291D, V292I, I293V, Q334Y, G335D, R356K, M357R, G359T, A376S, T377L, T386I, K390R, A400I, E404D, V435A, G436E, L452I, V466I, S468T, L469I, T470NS, D471E, H483Q, L491P, S519N, K527Q, K530R, A534S, A554S  
  18ZA.24 3TC, D4T NVP M184V V106A V35T, E36A, T39E, S48T, V60I, K122E, K173A, Q174K, I178L, G196E, T200A, E203K, Q207E, V245Q, A272P, E291D, V292I, I293V, Q334D, G335D, R356K, M357R, G359T, A376S, T377L, T386I, K390R, A400I, E404D, V435A, G436E, L452I, V466I, S468T, L469I, T470S, D471E, H483Q, L491P, S519N, K527Q, K530R, A534S, A554S  
  18ZA.36 3TC, D4T NVP M184V V106A, F227FL, N348NI V35T, E36A, T39E, S48T, V60I, K122E, K173A, Q174K, I178L, G196E, T200A, E203K, Q207E, V245Q, A272P, E291D, V292I, I293V, Q334D, G335D, R356K, M357R, G359T, A376S, T377L, T386I, K390R, A400I, E404D, V435A, G436E, L452I, V466I, S468T, L469I, T470S, D471E, H483Q, L491P, S519N, K527Q, K530R, A534S, A554S W410W* 
19ZA 19ZA.0 None None  K101KE, G190GA K20R, V35T, E36A, T39E, S48T, K103R, K122E, D123N, E169EQ, Q174K, T200A, R211K, F214L, V245Q, E248D, A272P, K275R, K277R, Q278H, E291D, V292I, I293V, P294T, I329IL, Q334H, G335D, R356K, G359T, T377LM, K390R, E396D, T397I, A400T, E404D, V435I, N447NH, E449ED, L452LQ, R461K, V466I, S468SA, T470N, D471E, T477A, H483Q, L491P, E514D, L517I, S519T, K527T, K530R, A534S, A554S  
  19ZA.24 3TC, D4T EFV M184IV K103S, G190A, N348NI K20R, E28EG, V35T, E36A, T39E, S48T, K122E, D123N, Q174K, T200A, R211K, F214L, V245Q, E248D, A272P, K275R, K277R, Q278H, E291D, V292I, I293V, P294T, I329L, Q334H, G335D, R356K, G359T, T377L, K390R, T397I, A400T, E404D, E449D, R461K, V466I, S468A, T470N, D471E, T477A, H483Q, L491P, E514D, L517I, S519T, K527T, K530R, A534S, A554S W153W*, E396DN 
20ZA 20ZA.0 None None   K20R, V35T, E36A, T39D, S48T, V60VI, K122E, D123DG, K173A, Q174K, D177E, T200A, Q207E, V245Q, E248D, T286A, E291D, I293V, K311KR, Q334H, G335D, R356K, G359ST, A376AG, T377L, K390R, E404D, F416Y, V435VA, L452I, V467I, S468SP, D471E, H483K, L491S, S519N, K527KR, E529ED, K530R, A534S, A554N  
  20ZA.108 3TC, D4T EFV M184V K103N K20R, V35T, E36A, T39E, S48T, K122E, D123G, I135L, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, E248D, T286A, E291D, I293V, E297K, Q334H, G335D, R356K, G359T, T377L, K390R, A400T, E404D, F416Y, L452I, V466I, V467I, D471E, H483K, L491S, S519N, K527R, E529D, K530R, A534S, A554N  
21ZA 21ZA.0 None None   V35T, E36A, T39E, S48T, K102KR, K166KR, K173A, Q174N, T200AE, Q207A, R211K, V245Q, D250E, A272P, K277R, T286A, E291D, V292I, I293V, K311KR, D324E, G335D, R356K, G359T, T377I, K390R, A400T, E404D, V435A, E449D, L452LI, V458VI, V466I, V467VI, D471E, Q480K, L491S, K527N, K530R, A534S, A554S  
  21ZA.72 3TC, D4T NVP   V35T, E36EA, T39E, S48T, K102KR, K104KR, K166KR, K173A, Q174N, T200A, Q207A, R211K, V245Q, D250E, A272P, K277R, T286A, E291D, V292I, I293V, K311KR, D324E, G335D, R356K, G359T, T377I, K390R, A400T, E404D, V435A, E449D, L452LI, V458VI, V466I, V467VI, D471E, Q480K, H483HY, L491S, K527N, K530R, A534S, A554S  
22ZA 22ZA.0 None None   V35T, E36A, T39E, S48T, V60I, K122E, D123G, K173A, Q174K, D177E, I178L, T200A, R211K, V245Q, S251SN, A272P, K277R, T286A, E291D, V292I, I293V, Q334D, G335D, R356K, G359T, I375V, T377L, K390R, E399D, A400I, E404D, V435A, N447NH, L452KN, V466I, T470S, D471E, H483Q, L491PS, S519N, E529EK, K530R, A534S, A554S  
  22ZA.72 3TC, D4T NVP   V35T, E36A, T39E, S48T, V60I, K122E, D123G, K173A, Q174K, D177E, I178L, T200A, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, Q334D, G335D, R356K, G359T, I375V, T377L, E399D, A400I, E404D, V435A, N447H, L452K, V466I, T470S, D471E, H483Q, L491T, S519N, K530R, A534S, A554S  
23ZA 23ZA.0 None None   K11Q, V35T, T39N, S48T, V60I, K122E, D123K, K173T, T200A, Q207G, R211K, V245Q, E248D, D250E, A272P, K277R, E291D, V292I, I293V, I326IV, Q334DE, G335D, R356K, G359T, T377Q, V381I, K390R, A400I, E404D, V466I, D471E, H483Q, L491P, I495V, S519N, K530R, A534S, A554N  
  23ZA.132 3TC, D4T EFV   K11KQR, V35T, E36EA, T39X, S48T, V60I, K122E, D123N, S162ST, K173KT, T200A, Q207G, R211K, V245Q, E248D, D250E, A272P, K277R, E291D, V292I, I293V, I326IV, Q334D, G335D, R356K, G359T, A376S, T377Q, K390R, A400I, E404D, V466I, D471E, H483Q, L491P, I495V, L517LI, S519N, K530R, A534S, A554N  
24ZA 24ZA.0 None None  K103N, E138A V35T, E36A, T39D, S48T, K122E, D123GS, S162A, K173T, T200A, Q207D, R211K, D250E, A272P, K275Q, K277KR, Q278H, T286A, E291D, V292I, I293V, P294S, Q334H, G335D, R356K, G359T, K366R, T369A, T377LM, K390R, A400T, E404D, V435VI, N447I, L452I, V467I, T470S, D471E, T477A, H483Q, L491S, S519N, K527N, K530R, V531I, A534S, A554S  
  24ZA.48 3TC, D4T NVP M184V K103N, E138A, N348I V35T, E36A, T39D, S48T, K122E, D123G, I135T, S162A, K173T, T200A, Q207D, R211K, D250E, A272P, K275Q, Q278H, T286A, E291D, V292I, I293V, P294S, Q334H, G335D, R356K, G359T, K366R, T369A, T377L, K390R, E399G, A400T, E404D, N447I, L452I, V467I, T470S, D471E, T477A, H483Q, L491S, L517X, S519N, K527N, K530R, V531I, A534S, A554S  
  24ZA.60 3TC, D4T NVP V75VI, M184V K103N, E138A, N348NI V35T, E36A, T39D, S48T, K122E, D123G, I132IL, I135IT, S162A, K173T, T200A, Q207D, R211K, D250E, A272P, K275Q, Q278H, T286A, E291D, V292I, I293V, P294S, Q334H, G335D, R356K, G359T, K366R, T369A, T377L, K390R, T397TA, E399EG, A400T, E404D, N447I, L452I, V467I, T470S, D471E, T477A, H483Q, L491S, S519N, K527N, K530R, V531I, A534S, A554S  
25ZA 25ZA.0 None None   E28A, V35T, T39E, S48T, K122E, D123G, I135T, S162C, K173A, Q174K, D177E, T200A, Q207A, R211K, F214L, K238R, V245Q, D250E, K277R, T286A, E291D, V292I, I293V, E302EK, Q334E, R356K, M357ML, G359T, T377L, K390R, A400T, E404D, V417VI, E432D, L452K, V466I, S468P, D471E, T477A, H483L, G490GE, L491X, E492EK, S519N, K527N, K530R, V531I, A534S, A554N, K558R  
  25ZA.48 3TC, D4T EFV  V106M E28A, V35T, E36EA, T39E, S48T, K122E, D123G, I135T, S162C, K173A, Q174K, D177E, T200A, Q207A, R211K, F214L, K238R, V245Q, D250E, A272AP, K277R, T286A, E291D, V292I, I293V, Q334E, R356K, G359T, T377L, K390R, A400T, E404D, E432D, L452K, V466I, S468P, D471E, T477A, H483L, G490E, L491V, E492K, S519N, K527N, K530R, V531I, L533M, A534S, A554N, K558R  
26ZA 26ZA.0 None None   V35T, E36A, T39E, K173I, Q174K, T200E, Q207E, R211K, V245Q, D250E, S251C, A272P, T286V, V292I, I293V, I329L, Q334D, G335D, R356K, M357K, G359T, A360T, V365I, E370D, A376S, T377M, K390R, E399D, A400M, E404D, E432D, I434M, V435T, A437V, L452I, K454R, S468T, D471E, H483Q, L491S, S519N, K530R, A534S, A554N  
  26ZA.12 3TC, D4T NVP  K103KN V35T, E36A, T39E, K173I, Q174K, T200E, Q207E, R211K, V245Q, D250E, S251C, A272P, T286V, V292I, I293V, I329L, Q334D, G335D, R356K, M357K, G359T, A360X, V365I, E370D, A376S, T377M, K390R, E399D, A400M, E404D, E432D, I434M, V435T, A437V, L452I, K454R, S468T, D471E, H483Q, L491S, S519N, K530R, A534S, A554N K281KN 
  26ZA.36 3TC, D4T NVP M184V K103N, Y181C, N348NI V35T, E36A, T39E, K49KR, K173I, Q174K, T200E, E203G, Q207E, R211K, V245Q, D250E, S251C, A272P, T286V, V292I, I293V, I329L, Q334D, G335D, R356K, M357KR, G359T, A360T, V365I, E370D, A376S, T377M, K385KR, K390R, E399D, A400M, E404D, E432D, I434M, V435T, A437V, L452I, K454R, S468T, D471E, H483Q, L491S, S519N, K530R, A534S, A554N  
27ZA 27ZA.0 None None   V35T, T39E, S48T, K122E, D123N, A158AS, K173A, Q174K, D177E, G196M, T200A, E204ED, Q207DE, V245Q, D250E, A272P, K281R, T286A, E291D, I293V, I326IV, Q334X, G335D, R356K, G359T, T377L, S379C, K390R, A400T, E404D, V435A, L452Q, V466I, S468P, D471E, T477A, H483Q, L491S, L517I, S519N, K527N, K530R, V531I, A534S, A554S  
  27ZA.39 3TC, D4T EFV   V35T, T39E, S48T, K122E, D123N, A158AS, K173A, Q174K, D177E, G196M, T200A, E204D, Q207E, V245Q, D250E, A272P, K281R, T286A, E291D, I293V, Q334QH, G335D, R356K, G359T, T377L, S379C, K390R, A400T, E404D, V435A, L452LQ, V466I, S468SP, D471E, T477A, H483Q, L491S, L517I, S519N, K527N, K530R, V531I, A534S, A554S  
28ZA 28ZA.0 None None  K103N V35T, E36A, T39E, K122E, D123G, I135V, S162C, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, E248D, K277R, K281R, T286A, E291D, V292I, I293V, P313Q, Q334H, G335D, R356K, G359T, T377L, K390R, A400T, E404D, V435A, L452M, S468P, D471E, T477A, H483Q, L491S, S519N, K527N, V531I, A534S, A554S  
  28ZA.84 3TC, D4T NVP M184V K103N, Y181C, N348I K20KR, V35T, E36A, T39DE, K122E, D123G, I135IV, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, E248D, K277R, T286A, E291D, V292I, I293V, P313Q, Q334H, G335D, R356K, G359T, T377LR, K390R, A400T, E404DN, V435A, L452M, S468P, D471E, T477A, H483Q, L491S, S519N, K527N, V531I, A534S, A554S  
29ZA 29ZA.0 None None   V35T, T39E, S48T, K103R, K122E, D123N, K173T, Q174R, G196E, T200A, Q207E, R211K, F214L, V245K, A272P, K277R, T286A, V292I, I293V, Q334H, G335D, R356K, G359AT, A376S, T377L, K390R, A400T, E404D, L452I, V466I, T470S, D471E, T477A, H483Q, L491PS, I495V, S519N, K527N, K530R, V531I, A534S, A554S  
  29ZA.72 3TC, D4T EFV M184V K103N V35T, E36A, T39E, S48T, K122E, I135L, K173T, Q174K, T200A, Q207E, R211K, V245K, D250E, A272P, K277R, T286A, E291D, V292I, I293V, L310I, Q334H, G335D, N348H, R356K, G359T, A376T, T377L, T386A, K390R, A400T, E404N, K451KR, L452LI, V466I, T470S, D471E, T477A, H483Q, L491LS, I495IV, Y501YH, L517I, S519N, K527N, K530R, V531I, A534S, A554NS  
30ZA 30ZA.0 None None  K103KN, V106VM P4S, V35T, E36A, T39E, S48T, K122E, D123G, T165TI, K173T, Q174X, D177E, I178L, T200A, Q207E, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, P294T, Q334H, G335D, R356K, G359T, T377M, K390R, A400T, E404D, V435A, D460DN, R461K, V466I, D471E, T477A, H483Q, S519N, K527N, K530R, A534S, A554RS  
  30ZA.04 3TC, D4T NVP  K103KN, Y181YC P4S, V35T, E36A, T39E, S48T, K122E, D123G, K173T, Q174X, D177E, I178L, T200A, Q207E, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, P294T, Q334H, G335D, R356K, G359T, T377M, K390R, A400T, E404D, V435A, D460DN, R461K, V466I, D471E, T477A, H483Q, S519N, K527N, K530R, A534S, A554RS  
  30ZA.24 3TC, D4T NVP M184V K103KN, N348NI P4S, V35T, E36A, T39E, S48T, K101X, K122E, D123GS, K173T, Q174A, D177E, I178L, T200A, Q207E, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, P294T, Q334H, G335D, R356K, G359T, T369TI, T377M, K390R, A400T, E404D, V435A, D460DN, R461K, V466I, D471E, T477A, H483Q, L517I, S519N, K527N, K530R, A534S, A554S  
31ZA 31ZA.0 None None   V35T, E36A, T39E, S48T, V60I, K122E, D123G, K173A, D177E, T200AV, Q207E, R211K, V245Q, K277R, T286A, V292VI, I293V, Q334C, G335D, R356K, G359T, T377L, K390R, A400R, E404D, V435A, G436E, V466I, S468T, L469I, D471E, H483Q, L491S, S519N, A534S, A554NS  
  31ZA.96 3TC, D4T NVP M184V V108I, Y181C, H221Y V35T, E36A, T39E, S48T, K122E, D123G, K173A, D177E, T200V, Q207E, R211K, V241VI, V245Q, K277R, T286A, I293V, Q334C, G335D, R356K, G359NT, V365VI, T377L, K390R, A400R, E404D, V435A, G436E, V466I, V467I, S468T, L469I, D471E, H483Q, L491S, S519N, A534S, A554S  
32ZA 32ZA.0 None None   V35T, E36A, T39E, E40ED, S48T, V60I, T165I, K173A, D177E, T200A, Q207E, R211K, V245Q, A272P, I274IV, K275KR, K281KR, T286A, E291D, V292I, I293V, Q334D, G335D, R356K, M357R, G359T, A376S, T377M, S379SC, K388KR, K390R, A400IT, E404D, F416Y, V435P, R461K, V466S, T470TK, D471E, H483Q, L491S, S519N, Q524L, A534S, A554KR  
  32ZA.96 3TC, D4T EFV M184V K103N K20R, V35T, E36A, T39E, S48T, V60I, I135IL, T165IV, K173A, D177E, T200A, Q207E, R211K, V245Q, A272P, K275KR, T286A, E291D, V292I, I293V, D324DE, Q334D, G335D, R356K, M357R, G359T, A371AV, A376S, T377M, S379C, K390R, A400T, E404D, F416Y, V435X, R461K, V466S, T470TK, D471E, H483Q, L491S, S519N, Q524L, A534S, A554K  
33ZA 33ZA.0 None None   K20R, V35T, T39A, E40D, K122E, D123S, I135R, S162C, K173A, T200A, Q207AE, R211K, F214L, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, V292I, I293V, V317A, Q334H, G335D, R356K, G359T, T377L, K390R, A400T, E404D, E432D, V435A, A445AG, E449ED, K465KR, V466I, V467VI, T470P, D471E, T477A, Q480H, H483Q, L491PS, S519N, K527N, K530R, V531I, A534S, A554K  
  33ZA.96 3TC, D4T EFV M184V K101E, K103N, V108VI, P225H K20R, V35T, T39A, E40D, K122E, D123S, I135R, S162C, K173A, T200A, Q207A, R211K, F214L, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, V292I, I293V, V317A, Q334H, G335D, R356K, G359T, T377L, K390R, A400T, E404D, E432D, V435A, A445G, E449D, V466I, V467I, T470P, D471EK, T477A, Q480H, H483Q, L491S, Q509QL, S519N, K527N, K530R, V531I, A534S, A554K  
34ZA 34ZA.0 None None   K20R, V35T, E36A, T39E, E53D, K122E, D123G, A158AS, S162X, T165TI, K166KR, K173T, D177E, T200A, Q207E, R211K, V245Q, D250DE, A272P, K277R, T286A, E291D, V292I, I293V, Q334H, G335D, R356K, G359T, T377L, K390R, A400T, E404D, V435A, A437V, D471E, H483Q, L491S, S519N, Q524E, K530R, A534S, A554S  
  34ZA.48 3TC, D4T EFV  K103N K20R, V35T, E36A, T39E, E53D, K122E, D123G, A158S, K166R, K173T, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, Q334H, G335D, R356K, G359T, T377L, K390R, A400T, E404D, V435A, A437V, D471E, H483Q, L491S, S519N, Q524E, K530R, A534S, A554S  
35ZA 35ZA.0 None None   V35T, E36A, T39D, S48T, W88WC, K122E, D123G, I135IT, E138X, T139TR, I142IT, K173A, Q174K, D177E, T200A, Q207E, F214L, V245HQ, D250E, K277R, T286A, E291D, V292I, I293V, Q334NY, G335D, R356K, G359T, T369A, T377L, T386I, K390R, A400I, E404D, E413D, V435A, T470S, D471E, H483Q, L484I, L491S, V496I, S519N, Q524QL, K530R, A534S, A554K, K558R  
  35ZA.84 3TC, D4T EFV  V179D V35T, E36A, T39D, S48T, W88C, K122E, D123G, I135T, E138S, K173A, Q174K, D177E, T200A, Q207E, F214L, V245H, D250E, K277R, T286A, E291D, V292I, I293V, Q334NY, G335D, R356K, G359T, T369A, T377L, T386I, K390R, A400I, E404D, E413D, V435A, T470S, D471E, H483Q, L484I, L491S, V496I, S519N, Q524L, K530R, A534S, A554K, K558R  
36ZA 36ZA.0 None None   V35T, T39E, S48T, D121H, K122E, D123S, I135V, I142IV, S162C, K173I, Q174K, D177E, I178L, T200A, Q207E, R211K, L228Q, V245Q, E248D, A272P, K275R, K277R, Q278H, L279M, T286A, E291D, V292I, I293V, P294T, Q334N, G335D, R356K, G359S, T377M, K390R, A400T, V435LPS, A446S, L452V, S468T, D471E, T477S, H483Q, L491S, E516D, S519N, K527KN, K530R, V531I, A534S, A554N  
  36ZA.120 3TC, D4T EFV M184V K103N, E138EA, H221Y, M230L, L234I V35T, T39E, S48T, D121H, K122E, D123S, I135V, S162C, K173IR, Q174K, D177E, I178L, T200A, Q207E, L228Q, V245Q, E248D, A272P, K275R, Q278H, L279M, T286A, E291D, V292I, I293V, P294T, Q334N, G335D, R356K, G359S, V365I, A371V, T377LM, K390R, A400T, V435P, A446S, L452V, R461RK, V467VI, S468T, D471E, T477AS, H483Q, L491S, E516D, S519N, K527N, K530R, V531I, A534S, A554N  
37ZA 37ZA.0 None None   V35T, E36A, T39E, S48T, K122E, D123G, S162N, K173A, Q174K, D177E, I178L, T200A, Q207E, R211K, F214L, V245Q, A272P, T286A, E291D, V292I, I293V, L301F, V317A, Q334D, G335D, A355G, R356K, G359T, T377L, K390R, A400I, E404D, V435A, E449D, L452LI, T470S, D471E, H483Q, L491S, S519N, K527X, K530R, A534S, A554S  
  37ZA.36 3TC, D4T NVP M184V K103KN I31IL, V35T, E36A, T39E, S48T, K101KN, V106X, K122E, D123G, S162N, K173A, Q174K, D177E, I178L, T200A, Q207E, R211K, F214L, V245Q, A272P, T286A, E291D, V292I, I293V, L301F, V317VA, Q334D, G335D, A355G, R356K, G359T, T377L, K390R, A400I, E404D, V435VA, E449D, L452I, T470S, D471E, H483Q, L491S, S519N, K530R, A534S, A554S  
38ZA 38ZA.0 None None   V35T, E36A, T39E, S48T, K122E, D123G, I135IV, S162X, T165TI, K166KI, D177E, T200A, Q207E, R211K, V245Q, A272P, K275R, K277R, Q278N, T286A, E291D, V292I, I293V, Q334H, G335D, R356K, M357R, G359T, T377M, K390R, A400T, E404D, V435VA, V466S, V467I, S468C, T470TN, D471E, H483Q, L491S, Q509H, S519N, K530R, A534S, A554S  
  38ZA.04 3TC, D4T NVP  K103KN V35T, E36A, T39E, S48T, K122E, D123G, S162X, T165TI, K166KI, D177E, T200A, Q207E, R211K, V245Q, A272P, K275R, K277R, Q278N, T286A, E291D, V292I, I293V, Q334H, G335D, R356K, M357R, G359T, T377M, K390R, A400T, E404D, V435VA, V466S, V467I, S468C, T470N, D471E, H483Q, L491S, Q509H, S519N, K527KN, K530R, A534S, A554S  
  38ZA.24 3TC, D4T NVP M184V K103N, K238N, N348I V35T, E36A, T39E, S48T, K49KR, K122E, D123G, I135IM, S162A, K166I, D177E, T200A, Q207E, R211K, V245Q, A272P, K275R, K277R, Q278N, T286A, E291D, V292I, I293V, Q334H, G335D, R356K, M357R, G359T, T377M, K390R, A400T, E404D, L452Q, V466S, V467I, S468C, T470N, D471E, H483Q, L491S, Q509H, S519N, K530R, A534S, A554S  
39ZA 39ZA.0 None None   V35T, E36A, T39E, E40D, S48T, K122E, D123S, K173A, Q174K, D177E, T200A, Q207KN, R211RM, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, K311R, Q334H, G335D, R356K, G359T, T377S, K390R, A400T, E404D, V435A, A437V, N447S, E449D, L452V, V467I, S468T, L469I, T470S, D471E, H483Q, L491PS, E492EK, S519N, K530KR, A534S, A554S  
  39ZA.84 3TC, D4T NVP M184V Y181C V35T, E36A, T39E, E40D, S48T, K49R, K122E, D123S, K173A, Q174K, D177E, T200A, Q207N, V241L, V245Q, A272P, T286A, E291D, V292I, I293V, K311R, Q334H, G335D, N348NT, R356K, G359T, T377LS, K390R, A400T, E404D, V435A, A437V, N447S, E449D, L452V, V467I, S468T, L469I, T470S, D471E, H483Q, L491S, Q509L, S519N, K530R, A534S, A554S  
40ZA 40ZA.0 None None   V35T, E36A, T39E, S48T, K122E, D123S, K173A, Q174K, D177E, T200A, E204ED, Q207A, R211K, V245Q, E248D, D250E, S251SN, A272P, K277KR, E291D, V292I, I293V, S322SL, I326V, G335D, R356K, G359S, T377LM, S379SC, K390R, K395KR, A400T, E404D, E413ED, V435A, E449ED, L452X, L469I, T470X, D471E, H483Q, L491LPS, S519N, K527KQR, K530R, A534S, A554NS  
  40ZA.84 3TC, D4T NVP   V35T, E36A, T39E, S48T, K122E, D123S, K173A, Q174K, D177E, I178L, T200A, Q207A, R211K, V245Q, E248D, D250E, A272P, K277R, E291D, V292I, I293V, I326V, G335D, R356K, G359S, T377L, S379C, K390R, A400T, E404D, V435A, L452M, L469I, D471E, H483Q, S519N, K527Q, K530R, A534S, A554S F61L 
41ZA 41ZA.0 None None   V35T, T39E, S48T, V60I, K122E, D123G, S162A, K166R, K173T, D177E, I178M, T200A, Q207G, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, Q334D, G335DN, R356K, M357R, G359T, T377Q, K390R, A400I, E404D, V435A, L452M, V466I, V467AT, T470S, D471E, T477A, H483Q, L491S, E514D, L517I, S519N, K527KN, A534S, A554S K287KN 
  41ZA.96 3TC, D4T EFV V75VI, M184V K101KE, K103N, G190A K20KR, V35T, E36A, T39E, S48T, V60I, K102KN, K122E, D123G, I132IL, I135IM, S162A, K166R, K173A, D177E, I178M, T200A, Q207R, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, Q334D, G335D, R356K, M357R, G359T, V365VI, T377Q, K390R, A400I, E404D, V435A, L452M, V466I, V467T, T470S, D471E, T477A, H483Q, L491S, E514D, L517I, S519N, A534S, V548I, A554S  
42ZA 42ZA.0 None None   V35T, E36EA, T39E, S48T, K122E, D123N, Q174N, T200A, Q207KN, R211RK, F214L, V245M, A272P, K275Q, K277R, Q278H, E291D, V292I, I293V, I329L, Q334DE, R356K, G359T, A376T, T377L, K390R, A400T, E404D, W410C, V435A, E449ED, L452X, R461K, V466I, S468T, T470N, D471E, T477A, H483Q, S519N, K527N, K530R, V531I, A534S, A554S  
  42ZA.36 3TC, D4T NVP M184V V106M, M230L V35T, E36A, T39E, S48T, K122E, D123N, Q174N, T200A, Q207N, R211K, F214L, V245M, A272P, K275Q, K277R, Q278H, E291D, V292I, I293V, P294T, I329L, Q334D, K347R, R356K, G359T, A376T, T377L, K390R, A400T, E404D, W410C, V435A, E449D, L452M, R461K, V466I, S468T, T470N, D471E, T477A, H483Q, S519N, K527N, K530R, V531I, A534S, A554S  
43ZA 43ZA.0 None None   V35T, T39K, S48T, V60I, K122E, D123X, S162C, K173A, P176PS, D177E, T200A, Q207A, R211K, V245Q, D250E, A272P, K277R, K281KR, T286A, E291D, V292I, I293IV, P294PT, E297EA, Q334E, G335D, R356K, M357R, G359T, A360AT, A376C, T377M, I380IV, K390R, I393IV, A400T, E404D, I434M, V435A, A437V, L452I, V467I, S468T, D471E, H483Q, L491S, L517I, S519N, Q524E, K530KR, A534S, A554S  
  43ZA.24 3TC, D4T NVP M184V V106VM, Y188C, N348NI V35T, T39K, S48T, V60I, K122E, D123S, K173A, D177E, T200A, Q207A, R211K, V245Q, D250DE, A272P, K277R, T286A, E291D, V292I, E297A, Q334E, G335D, R356K, M357R, G359T, A376C, T377M, K390R, A400T, E404D, I434M, V435A, A437V, L452IV, V467I, S468T, T470TN, D471E, H483Q, L491S, L517I, S519N, Q524E, K530KR, A534S, A554S  
  43ZA.84 3TC, D4T NVP M184V A98G, K101KE, Y181C, N348NI V35T, T39K, S48T, V60I, K122E, D123S, I135IT, K173A, D177E, T200A, Q207A, R211K, D218DE, V245Q, D250E, A272P, K277R, T286A, K287KQ, E291D, V292I, I293IV, E297A, Q334E, G335D, R356K, M357R, G359T, A376C, T377MR, K390R, A400T, E404D, I434M, V435A, A437V, L452IV, V467I, S468T, T470N, D471E, H483Q, L491S, L517I, S519N, Q524E, K530KR, A534S, A554S  
44ZA 44ZA.0 None None   P4PS, E6EQ, V35T, E36A, T39E, S48T, K122E, D123GS, K173A, Q174K, D177E, G196E, T200A, Q207X, R211EQ, V245Q, A272P, K277R, K281KR, T286A, E291D, V292I, I293V, K311KR, Q334E, G335D, R356K, G359T, T377L, K390R, A400T, E404D, E432D, V435A, A437AV, E449ED, L452M, S468T, L469I, T470S, D471E, H483Q, L491S, S519N, K530R, A534S, A554N  
  44ZA.48 3TC, D4T EFV M184V V106M, G190A P4S, V35T, E36EA, T39E, S48T, K122E, D123S, I135M, Q174K, D177E, T200A, Q207R, R211E, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, Q334E, G335N, R356K, G359T, T377L, K390R, A400T, E404D, E432D, V435A, L452M, S468T, L469I, T470S, D471E, H483Q, L491S, S519N, K530R, A534S, A554N  
45ZA 45ZA.0 None None   V8I, K32KE, V35T, E36EA, T39K, S48T, E53ED, V60I, K64KR, K122E, D123G, K173E, Q174QK, D177E, T200A, Q207A, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, I329L, Q334D, G335D, R356K, G359T, T377M, S379C, K390R, A400T, E404D, V435A, L452I, V458VI, R461K, L469I, T470S, D471E, H483Q, L491S, S519N, K530R, A534S, A554R