Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Sanabani (2011)
Title Characterization of partial and near full-length genomes of HIV-1 strains sampled from recently infected individuals in Sao Paulo, Brazil.
Citation PLoS ONE
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 50
NumPts 50
Subtype B, C, B + C


Clinical RT Isolates

SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
BR1002 BR1002 None None   E6A, V8I, V35T, V60I, K122E, I135T, I142V, R211S, A272P, T286A, I293V, E297K, L303M, V314I, Q334E, F346Y, M357T, I375V, K390R, E399D, A400T, T403I, V435I, S468P, K512R  
BR1013 BR1013 None None   I50V, V60I, S68G, K122E, I135T, I178L, Q197L, Q207D, A272P, K277R, A288S, I293V, E297A, P313Q, S322A, G333E, Q334R, F346L, I375V, T386I, K390R, T403M, R461K, S468P, A554T  
BR1020 BR1020 None None   D121H, K122E, I135T, D177E, T200I, Q207E, R211K, V245M, I293V, Q334L, T386I, K390R, T403M, L452S, S468P, T470K, Q480H, H483N, A534S  
BR1043 BR1043 None None   D121Y, K122E, I180V, G196E, R211K, F214L, V245M, Q278E, T286P, I293V, E297R, I326T, Q334L, F346L, R356K, M357T, A360T, T369A, A376T, T377K, T386A, K390R, A400T, N447H, S468P, H483N, L491S, A508T, A554T, K558R  
BR1046 BR1046 None None   K64R, K103R, K122E, N175H, T200A, Q207E, F214L, V245E, K277R, A288S, I293V, Q334E, M357T, V365I, K390R, E396D, A400T, T403S, F440Y, E449D, V467I, L491P, S519N, K527N, V531I, A554S  
BR1047 BR1047 None None   K122E, I135T, I178M, Q207H, R211K, V245M, A272P, V292I, I293V, E297A, K311R, Q334L, V365I, K366R, T386I, A400S, T403V, V435I, A446S, L491S, Q524E  
BR1049 BR1049 None None   K64R, D121H, K122E, I135T, D177E, I178M, R211K, V245M, A272P, K277R, L283I, I293V, E297A, S322T, A376T, S379G, T386I, K390R, A400T, V435I, K451R, R461K, L469I, I482V, A554S, I556V P119L 
BR1051 BR1051 None None   D177E, I178M, R211K, V245E, A272P, K281R, A288S, I293V, E297K, S322T, G335D, R356K, M357T, E370D, T377M, S379G, T386I, A400T, V435I, A446S, S468P, V531I  
BR1054 BR1054 None None   D121Y, D123E, Q207A, R211K, V245K, A272P, K277R, I293V, V317T, I326V, I329L, M357T, T386I, E404D, V435I, A446S, E449D, L469F, H483Y, V548I, A554S  
BR1055 BR1055 None None   E36D, E79D, R211G, V245M, I293V, P294A, S322T, I329V, M357V, A376S, V381I, T386I, T403I, K431T, H483Y, G490Q, L491S, K512R, A554N A98P, E399Q 
BR1057 BR1057 None None   K122E, Q174N, R211H, A272P, I293V, Q334Y, A376S, T377N, T386I, K390R, T403I, V466I, L517V, S519C, Q524E, A554T  
BR1064 BR1064 None None   K20R, I50V, R211K, V245M, I293V, T296S, E297R, D324E, A376T, S379G, T386I, T403I, H483Y, K527N, V548I, A554T  
BR1067 BR1067 None None  K103N E6D, R211K, E248D, A272P, T286A, V292I, I293V, E297K, L301M, Q334C, I341F, I382T, T386I, K390R, E399D, A400T, K431T, V435A, A446S, L452I, V466A, D471E, T477A, H483Q, L491S, E516D, K527N, K530R, A534S, V559I L279F 
BR1068 BR1068 None None   K122E, I135T, S162C, A272P, K277R, A288S, I293V, E297A, K311R, A376S, T386I, T403V, V435T, L517V, K530R, A554T  
BR1070 BR1070 None None   K49R, I135T, S162C, D177N, G196D, V245M, T286A, I293V, P313T, V317A, G333E, Q334R, F346L, M357T, V435G, L469I, H483Y, K512Q I341T 
BR1074 BR1074 None None   R72K, D123E, I135T, K166R, K173E, D192N, Q197E, Q207G, R211K, V245M, A272P, K277R, I293V, E297A, E312K, V317A, S322T, Q334L, Y342F, R358K, A360T, T386I, K390R, T403M, Y405S, S468P, Q480K, H483Q, S519N, I526V, A554T, K558R G155E 
BR1077 BR1077 None None   K20R, I135T, S163T, K173R, G196E, R211K, V245T, E248D, K277R, I293V, E297K, Q334H, A376T, T386I, K390R, T403I, T459A, R461K, V466A, V467I, S468P, Q480H, H483Y, S519G, A554N  
BR1078 BR1078 None None   K20R, K122E, I135T, S162C, R211K, V245M, K275R, I293V, E297A, V317A, I329L, M357T, A360T, T386I, A400T, T403M, E404D, P421L, E432D, G436E, L452A, E514D, A554S, V559I  
BR1079 BR1079 None None   E28A, V35I, D123E, I135T, S162A, D177E, G196E, R199K, F214L, K281R, I293V, P294S, E297T, Y342F, T386I, E399D, A400T, T403I, V435I, S468P, L517I, Q524E, E529D  
BR1080 BR1080 None None   T27I, K49R, K66R, S68G, T69N, I135T, S162C, R211Q, K277R, T286A, I293V, P294Q, G335D, R356K, G359S, T377L, K390R, A400T, V435A, D460N, V467I, T470N, L525M, K558R  
BR1081 BR1081 None None   K49R, D123E, I135T, S162C, E169D, T200A, V245K, A272S, K277R, I293V, I329V, K366R, K390R, T403M, S468P, H483Y, L491S, A508G, Q520L, K527N, E529Q, K530R  
BR1082 BR1082 None None   G15E, K20R, V21I, V60I, D123E, S162C, T200I, L210S, V245E, P294Q, K311R, M357V, K390R, A400T, T403M, L452V, R461K, V467I, T470A, H483Y, L491S, A554K Q91R 
BR1084 BR1084 None None   K49R, I135T, D177H, L210F, R211K, F214L, V245I, I293V, P321S, D324P, Q334Y, K347R, V365I, T386I, A400T, T403I, G490E, A554N  
BR1089 BR1089 None None   E6D, V35M, D123E, I159V, T200I, K201R, I202V, F214L, V276T, K277Q, K281R, I293V, E297V, G359S, V365I, T386I, K390R, T397A, T403V, V466A, V467I, T470M, H483Y, L517I, A554S  
BR1092 BR1092 None None   K32Q, L34*, E36Q, K122E, D123T, I135T, D177E, V245K, K275Q, K277R, I293V, E297K, L301I, I375V, T386I, K390R, A400S, S468P, Q487L, G490D, E516D, K530R, A554S E29A 
BR1093 BR1093 None None   V8I, V35T, E53K, V60I, I135T, I142V, R172K, R211K, A272P, T286A, I293V, E297K, L303M, Q334E, F346Y, M357T, K385R, K390R, E399D, A400T, T403I, V435I, E449D, S468P, H483R, K512R, V559I  
BR1094 BR1094 None None   K82R, D121Y, K122E, I135L, Q174H, G196E, R211K, F214L, V245M, Q278E, T286P, I293V, E297R, I326T, Q334L, R356K, M357T, R358K, A360T, T369A, A376T, T377K, T386A, F389L, K390R, A400T, P421X, L452S, S468P, H483N, A554T  
BR1095 BR1095 None None   K20R, S48X, K49R, E53X, P59X, D123E, I135T, I195T, T200A, R211K, V245M, K277R, A288S, I293V, Q334Y, M357S, T369A, I375V, T386I, K395R, A400T, K431T, L491S, Q520L, A554T, I556V  
BR1097 BR1097 None None   K20R, V21I, V35I, V60I, D123E, T200V, L210S, M357A, K390R, A400T, T403M, L452V, R461K, V466I, V467I, T470A, L491S, A554K  
BR1101 BR1101 None None   I135T, S162C, D177E, T200A, E204G, V245M, A272G, A288S, I293V, P294T, Q334N, G335S, M357T, A376T, T386I, K390R, A400T, T403I, K431R, L452S, V466I, H483Q, G490E, G543R, V548I, A554S  
BR1104 BR1104 None None   M41I, K122E, D123N, I135T, K154R, F171Y, D177E, I178V, T200E, V245M, E248D, A272P, M357V, A376T, T386I, T403I, T409P, P420S, P421S, P433L, E516A, V531I, A554T  
BR1107 BR1107 None None M184I  D121Y, K122E, I135T, F171Y, R211Q, F214L, V245I, I270V, V276I, L283I, R284K, I293V, K311R, I329L, R356K, G359S, A376S, T386I, K390R, T403R, E449D, T450S, L452V, S468P, S519N, A554K  
BR1110 BR1110 None None   K20R, I135T, S162T, S163T, K173R, G196E, V245T, E248D, I293V, E297K, Q334H, A376T, T386I, K390R, T403I, T450N, V467I, S468P, Q480H, H483Y, S519G, A554N  
BR1114 BR1114 None None   K20R, V35T, E36A, T39E, K43R, S48T, V60I, K104R, D121Y, K122E, I135T, T139A, K166R, D177E, Q197P, T200I, R211K, F214L, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, G335D, Y342F, R356K, M357K, G359T, K366R, T377Q, K390R, A400S, E404D, L452M, V466I, T470N, D471E, H483Q, L491S, S515V, S519N, K530R, A534S, A554Q  
BR1115 BR1115 None None   K20R, K102Q, D123E, I142V, S162Y, D177E, I178L, T200A, R211K, V245E, V276I, I293V, T296S, E297A, Q334E, M357T, E370Q, K390R, A400S, E413D, E449D, S468P, Q524E, A554N  
BR1119 BR1119 None None   R72K, D121H, K122E, I135T, K173Q, D177E, I195M, T200I, R211K, A272P, K277R, I293V, T296S, E297A, Q334L, K366R, T369V, A376T, T386I, A400T, T403V, V435M, R461K, S468T, L517I, A554T, K558R N57I, T58P, N81I 
BR1121 BR1121 None None   S162C, G196E, E203D, K277R, I293V, E297T, I341V, A360T, K366R, T369V, T386I, K390R, A400T, T403I, E413K, E415K, E430K, V435I, N447S, R448K, E449K, G453E, V458I, D460N, R463K, S468P, D488N, E492K, E514K, V531I, G541E, G543R, D549N, A554S G544K 
BR2018 BR2018 None None M184V K103N D123E, I135M, K166R, V189I, T200A, A272P, K281R, P294T, E297K, V317A, Q334N, Y342F, M357T, A376S, T377I, K390R, T397I, A400T, V435I, D460H, R461K, T470S, H483L, I506L, L517I, K527R, A554T  
BR2019 BR2019 None None   K20R, K49Q, Q197P, R211K, E248V, I293V, I329L, M357T, T386I, A400T, T403I, V435T, L452I, K530R, A554T  
BR2022 BR2022 None None   V35T, T39G, S48T, K101R, K122E, K173A, D177E, Q207G, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, P294T, D324P, G335S, P345T, R356K, G359T, T369A, T377V, K390R, E404D, V435A, G436E, N447S, L452M, V466I, S468T, D471E, H483Q, L491P, S519N, K530R, A534S, A554N  
BR2025 BR2025 None None   D121H, K122E, T165I, D177E, I178L, F214L, V245K, A272P, A288T, T296S, E297R, L301I, S379G, T386I, K390R, A400T, V435I, E449D, S468P, L517I, S519N, K530R, A554T, I556V, V559I  
BR2027 BR2027 None None   K20R, K49R, K104R, K122E, I135T, E169D, D177E, T200I, R211K, Q278H, K281R, A327V, G359S, T377I, T386I, K390R, T403I, E404D, S468P, L491V, E529D, A554T  
BR2028 BR2028 None None   V60I, D123E, I135T, D177E, I178M, G196E, A272P, K277R, L283I, I293V, E297T, Q334D, K390R, V435L, R461K, T470A, K476R, H483Y, K512R, A554S, K558R  
BR2029 BR2029 None None   V35I, R83K, D123E, I135V, A272P, K281R, T286A, E297K, A360T, K385R, K390R, Q394L, E399D, A400T, K431T, V435A, A446S, L452K, V466A, D471E, T477A, H483Q, L503I, S519N, A534S  
BR2032 BR2032 None None  V179E K20R, D123E, I135T, K173T, G196E, T200A, Q207H, R211K, A272S, I293V, E297Q, K311R, Q334L, T338S, I341V, Q367L, A376S, T386I, D460N, R461K, L517I, Q524E, A554S  
BR2033 BR2033 None None   K11R, V35I, R83K, I195L, G196E, T200I, R211K, E224K, V245M, A288S, E297R, S322T, I329L, F346Y, M357V, A376T, K390R, A400T, V435I, V458I, H483N, L491S, A554T E399A 
BR2036 BR2036 None None   K20R, K102Q, I135T, S162Y, R211K, V276I, Q278H, A288S, I293V, Q334L, I341V, M357V, T377I, T386I, T403I, K454R, R461K, H483Y, Q487L, S519N, A554T  
BR2040 BR2040 None None   V35T, E36A, T39D, K43R, S48T, K122E, D123S, T200A, Q207K, R211Q, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293V, A327V, G335D, R356K, G359T, T377L, K390R, E404D, L452I, V466I, D471E, H483Q, L491S, S519N, K530R, A534S, A554K, K558R  
BR2041 BR2041 None None   I135T, S162C, I178M, G196E, E203D, A272P, T286A, A288P, I293V, P313T, V317A, G333E, Q334R, M357T, A400S, S468P, T470K, H483Y, A502S, K512Q  
BR2042 BR2042 None None   D121Y, K122E, S162A, Q174H, G196E, R211K, F214L, V245M, Q278E, T286P, I293V, E297R, I326T, Q334L, R356K, M357A, R358K, A360T, T369A, A376T, T377K, T386A, K390R, A400T, N447H, L452V, S468P, H483N, L491S, A554T, K558R