Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Green (2011)
Title Drug resistance and coreceptor usage in HIV type 1 subtype C-infected children initiating or failing highly active antiretroviral therapy in south Africa.
Citation ARHR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 54
NumPts 54
Subtype C

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
707PKE01F 707PKE01F 3TC, D4T EFV K65R, K70~, V75M, K219R K103N, V106M L34I, V35T, E36A, T39E, E40D, V60I, S68SN, T69N, K122E, D123S, I135M, K173A, Q174K, D177E, I178L, T200A, I202IV, Q207E, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, V317A K73Q 
707PKE01N 707PKE01N Unknown Unknown   P4S, V35T, E36A, T39E, S48T, A98S, K122E, D123G, K173T, D177E, I178V, T200A, Q207E, R211S, V245Q, K277R, I293V  
707PKE02F 707PKE02F AZT, 3TC NVP D67N, K70R, M184V, T215F, K219E A98G, K103N, Y181C K20R, V35T, E36A, T39E, E40ED, S48T, V60I, T69N, K122E, D123S, K173A, T200A, E203ED, Q207E, R211K, L228LH, V245M, A272P, E291D, V292I, I293V, D320E, D324E  
707PKE02N 707PKE02N Unknown Unknown   V21I, V35T, T39E, K43KR, S48T, V60I, K122KE, D123DG, K173T, Q174K, D177E, G196E, T200A, Q207A, R211K, V245Q, A272S, E291D, V292I, I293V  
707PKE04F 707PKE04F 3TC, D4T, AZT EFV M41ML, D67DN, V75M, M184V, T215Y V106M, V179VD, G190GA, F227L I31L, V35T, E36EA, T39E, V60I, A98AS, L109LI, K122E, D123S, S163SC, T165TI, K173T, Q174N, D177E, T200A, Q207A, R211K, V245T, A272P, E291D, V292I, I293V, E298EK, D324E, I326IV  
707PKE05F 707PKE05F AZT, 3TC NVP, EFV D67N, K70R, M184V, K219Q A98G, K103N, Y318F K20KR, V35T, T39E, S48T, V60I, T69TN, K122E, D123S, I135T, S162A, K173A, D177E, T200A, Q207E, R211K, D218E, V245K, A272P, L283I, R284K, V292I, I293V, D324E  
707PKE06F 707PKE06F 3TC, D4T EFV D67N, K70R, M184V, K219Q L100I, K103N, H221Y, P225PH V35T, T39E, S48ST, V60I, T69X, K122E, I135IT, K173T, Q174K, D177E, T200A, Q207A, V245Q, A272P, K277KR, T286A, A288AT, E291D, V292I, I293V, D324DE  
707PKE07F 707PKE07F 3TC, D4T EFV M184V K103N, V108VI V35T, T39E, S48T, V60I, K122E, D123GS, I135IM, K173A, Q174K, D177E, T200A, Q207E, R211K, V245K, A272P, V276I, E291D, V292I, D324E I293IMV 
707PKE09F 707PKE09F 3TC, D4T EFV K70R, M184V V106M, Y188C K20KR, V35K, T39E, S48T, T58S, V60I, T69N, V118A, S162Y, K173T, Q174R, D177E, T200A, I202IV, Q207X, R211Q, L228LH, V245Q, D250E, V292VI, I293V, E297K, P321S, D324E, Q334E  
707PKE10F 707PKE10F 3TC, D4T EFV  E138A K20KR, V35T, T39E, S48T, K122E, D123G, K173A, Q174K, D177G, V179I, T200AE, Q207A, R211K, V245Q, A272P, K277KR, K281KR, T286A, E291D, V292I, I293V  
707PKE10N 707PKE10N Unknown Unknown   K20R, V35T, E36A, T39E, S48T, V60I, K173A, D177E, T200A, Q207E, R211K, V245Q, A272PS, I274IV, K277R, T286A, E291D, V292I, I293V L279LF 
707PKE11F 707PKE11F 3TC, D4T EFV K65R, T69~, K219R K103N, V106M, F227L K20R, T27S, V35T, T39E, S48T, V60I, S68N, K122E, D123S, T165I, K173A, Q174K, D177E, I195IL, G196E, T200A, Q207E, R211K, F214L, K223Q, L228R, V245Q, L283LI, E291D, V292I, I293V, S322T  
707PKE11N 707PKE11N Unknown Unknown   V35T, E36A, T39E, S48T, K122E, D123S, R172RK, K173T, D177E, T200A, R211K, V245K, A272PS, K275Q, K277R, Q278QH, T286A, E291D, V292I, I293V, I326V  
707PKE12F 707PKE12F 3TC, D4T None M184V  K11Q, L34I, V35T, E36A, T39D, S48T, V60I, K122E, D123G, K173T, D177E, T200A, Q207A, R211K, V245Q, A272P, T286A, E291D, I293V, D324DE, I329L, Q334E  
707PKE13F 707PKE13F AZT, 3TC NVP K70R, M184V, T215TI, K219E A98AG, K103N, Y181C P4S, V35T, T39N, S48T, V60I, D67X, S68SG, T69TN, V90VI, V118VI, S162N, K173T, Q174K, D177E, T200A, I202V, Q207A, R211K, F214L, D218DE, L228LR, V245Q, A272P, V292I, I293V, P294A, I329V, Q334E  
707PKE13N 707PKE13N Unknown Unknown   E6D, V35T, E36A, T39E, S48T, V60I, K122E, D123S, K173A, D177E, T200A, Q207E, V245Q, A272P, K275R, Q278N, T286TA, E291D, V292I, I293V  
707PKE15F 707PKE15F 3TC, D4T EFV M41L, D67N, L74V, M184V, T215Y, K219N K103S, V106M, M230L P4H, V35T, E36A, T39E, K43KQ, E44ED, S48T, V60I, A98AS, K102KR, V118I, K122E, D123S, K173A, Q174K, D177EG, I178IM, T200A, Q207A, R211K, K223E, V245Q, K277R, T286A, E291D, V292I, I293V  
707PKE16F 707PKE16F 3TC, D4T EFV L74LV, M184V L100LIM, K103N, V108VI, P225PH K20KR, V35T, T39E, S48T, V60I, K122E, D123G, I135T, K166R, K173A, D177E, T200A, I202IV, Q207A, R211K, F214FL, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, E297K  
707PKE17F 707PKE17F 3TC, D4T EFV F116Y, Q151M, M184V V106M, Y188C, G190GA E6K, V35T, T39E, S48T, S68SG, T69TN, K102X, K122E, I135IV, T139TA, K173A, Q174K, D177E, T200A, I202V, R211K, F214L, V245Q, A272P, T286A, E291D, V292I, I293V, Q334E  
707PKE17N 707PKE17N Unknown Unknown   K20R, V35IT, E36A, T39E, E40D, S48T, T69TN, K122E, D123N, S162C, K173A, D177E, T200A, Q207A, V245Q, E248D, A272P, K277R, Q278H, T286TA, E291D, V292I, I293V, D324E  
707PKE18F 707PKE18F 3TC, D4T EFV   V35T, E36A, T39E, S48T, V60I, K122E, D123DG, K173A, Q174K, D177E, T200A, E203D, Q207DE, R211RK, V245Q, E248D, A272P, K277KR, L283LI, T286TA, E291D, V292I, I293V  
707PKE18N 707PKE18N Unknown Unknown   V35T, E36A, T39E, S48T, V60I, K122E, D123N, I135V, I142V, K173AV, Q174K, D177E, T200A, Q207E, V245Q, A272P, K277R, T286V, E291D, V292I, I293V  
707PKE19F 707PKE19F 3TC, D4T None M184V  K20R, V35T, E36A, T39E, S48T, E53D, D121Y, K122E, K173A, Q174K, P176PS, V179VI, T200A, Q207E, R211K, F214FL, V245Q, T286A, E291D, V292I, I293V, S322T  
707PKE21F 707PKE21F AZT, 3TC NVP D67GS, K70R, M184V, T215FIV, K219E V108I, Y181C P4S, K20R, V35K, T39D, S48T, V60VI, T69N, V90VI, K101KT, K122E, D123S, S162HN, K166R, K173V, Q174K, D177E, T200A, I202IV, Q207E, R211K, L228R, V245Q, A272P, K277R, R284RK, T286A, E291D, V292I, I293V, S322A  
707PKE21N 707PKE21N Unknown Unknown   E6A, V35T, E36A, T39D, K122E, D123G, K173I, Q174K, I178M, T200A, Q207E, R211S, V245Q, A272K, K277R, T286A, E291D, V292I  
707PKE22F 707PKE22F 3TC, D4T EFV K65R, T69~, K70R, Q151M K103N, V106M L34V, V35T, E36A, T39E, S48T, V60I, S68G, V90I, K122E, D123G, T139E, A158S, K173A, D177E, I178M, T200A, Q207A, R211K, V245E, A272P, E291D, V292I, I293V, D324E  
707PKE22N 707PKE22N Unknown Unknown   V35T, E36A, T39E, S48T, E53D, D121Y, K122E, S162C, K173A, D177N, I178L, T200A, Q207E, R211K, V245Q, A272S, T286V, E291D, V292I, I293V  
707PKE23F 707PKE23F 3TC, D4T EFV M184V K103N, E138A, P225H V8I, V35T, T39N, S48T, V60I, K101Q, K122E, I135T, K173A, Q174K, G196E, T200A, I202IV, Q207E, R211K, F214L, L228LI, V245Q, E248ED, A272P, E291D, V292I, I293V, K311R  
707PKE23N 707PKE23N Unknown Unknown   V35T, E36A, T39E, S48T, V60I, K122E, D123N, K166R, K173A, Q174KR, D177E, T200A, Q207E, R211K, P243T, V245Q, A272P, K277R, T286A, E291D, V292I, I293V  
707PKE24F 707PKE24F 3TC, D4T EFV L74LV, M184V L100LI, K103N, H221HY, P225PH V35T, E36A, T39E, S48T, K122E, I135M, S162C, E169EA, K173A, Q174QK, D177E, I178FL, I195L, T200A, Q207E, R211K, L228LR, V245Q, A272P, K277R, K281R, T286A, E291D, V292I, I293V, D324E, Q334E  
707PKE25F 707PKE25F 3TC, D4T EFV M41ML, D67DN, K70KR, M184V, K219KQ V179D, Y188L E28A, V35T, T39E, S48T, V60I, K103R, K122E, D123G, I135X, I142T, K173A, D177DE, I178L, T200A, Q207E, R211RK, F214L, T215X, V245Q, A272P, K277R, T286A, E291D, V292I, I293V  
707PKE25N 707PKE25N Unknown Unknown   V8VI, K20R, V35T, T39E, S48T, V60I, K104R, K122E, D123S, I142IV, E169T, K173A, Q174K, D177E, I178L, E194A, G196E, T200A, Q207E, R211K, F214L, V245Q, D250E, V292I, I293V  
707PKE26F 707PKE26F 3TC, D4T EFV M41ML, K70KR, M184V, K219KR K101H, V106M, G190A P4T, K20KR, V35T, E36A, T39E, V60I, K122E, D123S, K173A, Q174K, D177E, T200A, I202V, Q207E, R211K, F214L, V245Q, E248ED, D250NS, A272P, T286A, E291D, V292I, I293V, P313Q, Q334E  
707PKE26N 707PKE26N Unknown Unknown  E138EG V35T, E36A, T39E, S48T, K122E, D123N, K173A, D177E, I178M, T200A, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, V317A  
707PKE27F 707PKE27F AZT, 3TC EFV M41L, D67N, K70R, V75M, F77L, M184V, T215Y, K219E V106M, G190A, F227L V35T, E36A, T39E, S48T, V60I, T69TN, A98S, L109I, K122E, D123S, I135T, S163T, K173A, Q174K, D177E, T200A, Q207E, R211K, D218E, L228H, P243T, V245Q, A272P, T286A, E291D, V292I, I329IV  
707PKE28F 707PKE28F 3TC, D4T EFV D67N, K70R, M184V, K219E V106M, V179D, F227FL K20R, V35T, E36A, T39E, V60VI, K101A, K103KR, K104R, K122E, D123N, I135IMT, E138S, T165I, K173M, Q174K, T200A, I202V, Q207E, R211K, F214L, V245Q, E248D, A272P, K277R, Q278N, T286A, E291D, V292I, I293V, P313T, V317A  
707PKE28N 707PKE28N Unknown Unknown   V35T, E36A, T39E, S48T, K122E, D123G, S162C, E169K, K173A, Q174K, T200A, Q207A, R211K, V245Q, A272P, I274V, K281R, T286A, V292I, I293V, S322A  
707PKE29F 707PKE29F 3TC, D4T EFV D67DN, M184V, K219R V106M, V179D, F227L K20R, V35T, T39E, V60VI, K102N, K122KE, I135V, S162SN, E169KR, K173E, Q174R, D177E, I178L, T200A, Q207E, R211K, F214L, V245Q, A272P, T286A, E291D, V292I, I293V, I326V  
707PKE31F 707PKE31F 3TC, D4T EFV   V8I, V35T, T39N, S48T, V60I, K122E, D123G, K173A, Q174K, D177E, T200A, Q207E, R211RK, V245Q, A272P, K277R, T286TA, E291D, V292I, I293V  
707PKE33F 707PKE33F ABC, D4T None M184V  I31IV, V35T, E36A, T39E, V60I, K102KR, V118VI, K122E, D123S, I135IL, I142K, T165I, K166R, K173A, Q174K, D177E, T200A, I202V, Q207A, F214L, V245Q, D250E, A272P, K275Q, T286A, E291D, V292I, I293V, V317VA  
707PKE34F 707PKE34F 3TC, D4T EFV D67N, K70R, M184V, K219Q K103N, V106M P4PS, K20R, V35T, S48T, K102KR, K122E, D123S, I135V, K166R, F171Y, K173A, Q174K, D177E, I178IM, G196E, T200A, E203ED, Q207E, R211K, F214L, L228LH, V245Q, A272P, K277R, I293V, D324E  
707PKE35F 707PKE35F 3TC, D4T EFV M184V, T215TI K101E, Y181C, G190S, H221Y V8VA, E28K, V35T, T39E, T69X, W88WC, V118I, K122E, D123N, T165I, K166KR, K173A, Q174K, D177E, T200A, Q207E, L210LS, F214L, V245Q, A272P, K275KQ, K281R, T286A, E291D, V292I, E297EK, Q334D  
707PKE36F 707PKE36F 3TC, D4T None   V8I, K11E, V35M, S48ST, D121Y, K122E, D123G, I135T, K173T, D177E, T200A, Q207EK, R211K, V245Q, E248T, A272P, A288S, E291D, V292I, I293V, I329L  
707PKE37F 707PKE37F 3TC, D4T EFV M41L, V75I, M184V, L210W, T215Y K103N, P225H K20R, V35T, E36EA, T39E, V60I, W88C, I132L, K173A, D177E, G196T, T200A, Q207E, R211K, T240TK, V245Q, D250E, K277R, T286A, E291D, V292I, I293V, D324E  
707PKE38F 707PKE38F 3TC, D4T None   V35T, E36A, T39E, S48T, K122E, D123DG, K173A, Q174K, D177E, T200A, Q207X, R211K, V245Q, A272P, K275Q, K277R, K281R, E291D, V292I, I293V, V317VA, I329L  
707PKE39F 707PKE39F 3TC, D4T EFV D67G, K70R, V75I, M184V, K219Q V106M, Y181C, F227L K20KR, V35T, T39E, S48T, V60I, K101KI, K122E, D123N, I132L, I135V, K173A, Q174K, D177E, T200E, E203K, Q207E, R211K, F214L, V245Q, A272P, K277R, E291D, V292I, I293V  
707PKE40F 707PKE40F 3TC, D4T None M184V Y181YC T27TS, V35T, E36A, T39E, E40D, K101R, K122E, D123N, I135T, T139A, D177E, T200A, Q207E, F214L, P243T, V245Q, A272S, T286A, E291D, V292I, I293V, P294T, D324E  
707PKE41F 707PKE41F D4T, DDI EFV M41L, D67N, L210W, T215Y A98G, G190S, K238T E6K, K20R, V35T, T39DE, V60I, V118I, K122E, D123G, K173A, D177E, V179I, T200A, Q207E, R211RK, V245K, A272P, K275R, Q278H, T286A, E291D, V292I, I293V, D324E, I329L  
707PKE43F 707PKE43F 3TC, D4T None   P4PS, E6EK, V35T, E36A, T39E, S48T, K122E, D123S, K173T, V179A, T200A, Q207A, R211K, V245Q, A272P, V292I, I293V, I329V  
707PKE44F 707PKE44F 3TC, D4T EFV M184V K103N, V106VM, P225PH, Y318YF V35T, T39E, S48T, K49R, E53D, V60I, K122E, D123S, I135ILM, S162D, K166R, E169R, K173E, Q174K, D177E, G196E, T200A, Q207E, V245Q, A272P, K277R, T286A, E291D, V292I, I293V  
707PKE49F 707PKE49F 3TC, D4T, AZT, DDI EFV M41L, L210W, T215Y K103N, Y188L V35I, T39E, E44ED, S48T, A98AS, K102G, K122E, D123S, K173T, Q174K, T200A, Q207A, H208HY, R211K, F214FL, V245E, K277R, L283I, T286A, E291D, V292I, I293V, E297EK, D324E, I329L  
707PKE50F 707PKE50F 3TC, D4T EFV D67DN, M184V, K219EQ V106M, V179D P4S, K20KR, V35T, T39E, S48T, V60I, K122E, D123S, I135M, D177E, T200A, Q207E, R211K, V241VL, V245N, A272P, T286A, E291D, V292I, I293V, S322A, D324E  
707PKE51F 707PKE51F 3TC, D4T, AZT, DDI EFV D67N, K70R, K219Q K101E, V106M, V179VD K32R, V35T, T39N, E40D, V60I, T69TN, K122E, D123S, T139TS, K173A, Q174K, D177E, I178LV, T200A, E203ED, Q207E, R211RK, F214L, T215X, V245Q, A272P, K277R, Q278H, K281R, T286A, E291D, V292I, I293V, E297K  
707PKE52F 707PKE52F 3TC, D4T EFV D67G, K70R, M184V, K219Q A98AG, K103KN, V106VM, Y188L K11KR, V35T, T39E, S48T, E53D, V60I, S68G, K102KE, V118VI, K122E, D123S, I135V, K173A, Q174R, D177E, G196GE, T200A, Q207E, R211K, F214L, L228H, Q242H, V245Q, A272Q, T286TA, E291D, V292I, I293V, D324E, G333E, Q334H  

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