Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Green (2011)
Title Drug resistance and coreceptor usage in HIV type 1 subtype C-infected children initiating or failing highly active antiretroviral therapy in south Africa.
Citation ARHR
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 54
NumPts 54
Subtype C

 

Clinical PR Isolates


SubjectIsolatePIsWksPIMajorPIMinorCommonUnusual
707PKE01F 707PKE01F None    T12S, I15V, L19I, K20R, M36I, R41K, H69K, L89M, I93L  
707PKE01N 707PKE01N Unknown    K14R, I15V, G16E, L19I, K20R, M36L, N37S, R41K, H69K, V77I, L89M, I93L  
707PKE02F 707PKE02F None    T12S, K14R, L19I, M36I, N37S, R41K, H69K, L89M  
707PKE02N 707PKE02N Unknown    I15V, M36MI, R41RK, L63P, H69K, V77VI, L89M, I93L  
707PKE04F 707PKE04F None    I15V, L19V, M36I, R41K, L63T, H69K, T74S, L89M, I93L  
707PKE05F 707PKE05F None    I15V, L19I, M36I, R41K, H69K, T74S, L89M, I93L  
707PKE06F 707PKE06F None    T12S, I15V, L19I, M36I, R41K, L63P, H69K, L89M, I93L  
707PKE07F 707PKE07F None    T12S, I15V, L19I, M36I, R41K, L63I, H69K, V82I, L89M, I93L  
707PKE09F 707PKE09F None    I15V, L19I, E35D, M36I, R41K, D60E, Q61E, L63LP, H69K, L89M, I93L  
707PKE10F 707PKE10F None    T12S, I15V, L19I, M36I, R41K, K45R, D60DE, Q61X, I62IV, L63Q, I64L, H69K, L89M, I93L  
707PKE10N 707PKE10N Unknown    T12P, I15V, L19I, M36I, N37S, L63P, H69K, L89M, I93L  
707PKE11F 707PKE11F None    T12S, I15V, L19T, K20R, E35D, M36I, R41K, D60E, Q61E, H69K, L89M, I93L  
707PKE11N 707PKE11N Unknown    T12S, I15V, L19I, E35D, R41K, D60E, Q61H, L63P, H69K, K70Q, L89M, I93L  
707PKE12F 707PKE12F LPV 81   T12S, I15V, L19I, E35D, M36I, R41K, L63P, H69K, L89M, I93L  
707PKE13F 707PKE13F None    T12S, I15V, L19V, M36I, R41K, H69K, I72IV, L89M, I93L  
707PKE13N 707PKE13N Unknown    L10V, L19T, K20KR, M36I, R41K, L63LP, H69K, L89M, I93L  
707PKE15F 707PKE15F None    T12S, K14R, I15V, L19I, M36I, R41K, H69K, L89IM, I93IL  
707PKE16F 707PKE16F None    T12A, K14KR, I15V, M36I, R41K, H69K, L89M, I93L  
707PKE17F 707PKE17F None    I15V, E35D, M36I, N37Q, R41K, K45R, L63P, H69K, L89M, I93L  
707PKE17N 707PKE17N Unknown    L10LV, T12TS, I15IV, L19I, M36L, N37S, R41K, H69K, L89M, I93L  
707PKE18F 707PKE18F None    L10M, T12S, I15V, L19V, E35D, M36I, R41K, I62V, L63I, H69K, T74S, L89M, I93L  
707PKE18N 707PKE18N Unknown    T12S, I15IV, L19V, M36I, R41K, H69K, L89M  
707PKE19F 707PKE19F RTV, LPV 131 M46I, I54V, L76V, V82A Q58E L10I, T12S, I15V, L19T, K20R, E35D, M36I, R41K, I62V, L63P, H69K, L89M, I93L  
707PKE21F 707PKE21F None    T12S, I15V, G17D, M36I, R41K, L63P, H69R, I93L  
707PKE21N 707PKE21N Unknown    T12S, I15V, L19T, K20R, E35D, M36I, R41K, L63P, H69K, I93L  
707PKE22F 707PKE22F None    T12S, I15V, L19I, M36I, R41K, L63P, H69K, I93L  
707PKE22N 707PKE22N Unknown    T12AE, K14KR, I15V, G16E, L19I, M36I, R41K, L63S, H69K, L89M, I93L  
707PKE23F 707PKE23F None    T12S, K14KR, I15V, L19V, M36I, R41K, H69K, L89M, I93L  
707PKE23N 707PKE23N Unknown    T12S, I15V, L19I, M36I, R41K, H69K, L89M, I93L  
707PKE24F 707PKE24F None    T12S, I15V, L19T, M36I, R41K, L63P, H69K, I93L  
707PKE25F 707PKE25F None    T12TS, I15V, L19T, K20R, M36I, R41K, H69K, L89M, I93L  
707PKE25N 707PKE25N Unknown    T12S, I15V, L19V, K20R, E35D, M36I, R41K, K45KR, H69K, T74S, L89M, I93L  
707PKE26F 707PKE26F None    I15V, L19V, K20R, E35D, M36I, R41K, K45KR, H69K, L89M, I93L  
707PKE26N 707PKE26N Unknown    T12S, I15V, L19V, K20R, M36I, R41K, L63S, H69K, K70Q, I72K, V77I, L89M, I93L  
707PKE27F 707PKE27F None    T12S, L19T, K20R, M36I, R41K, L63LP, H69K, L89M, I93L  
707PKE28F 707PKE28F None    T12S, I15V, G17D, L19I, K20R, E35D, M36I, P39Q, R41K, D60E, Q61D, L63AT, H69K, L89M, I93L  
707PKE28N 707PKE28N Unknown    I15V, L19T, K20R, M36IL, N37NS, R41K, L63P, H69K, V77I, L89M, I93L  
707PKE29F 707PKE29F None    T12S, I15V, L19V, K20KR, E35D, M36I, R41K, Q61E, H69K, T74S, L89M, I93L  
707PKE31F 707PKE31F None    T12S, I15V, L19I, R41K, H69K, T74S, V77I, L89M, I93L  
707PKE33F 707PKE33F LPV    T12S, I15V, L19V, E35D, M36I, R41K, L63P, H69K, I93L  
707PKE34F 707PKE34F None    T12S, I15V, L19I, M36I, L63P, H69K, I93L  
707PKE35F 707PKE35F None    T12S, L19I, K20R, M36I, R41K, H69K, L89M, I93L  
707PKE36F 707PKE36F LPV 87   T12S, I15V, L19I, M36IT, N37NS, R41K, L63LP, H69K, L89M, I93L  
707PKE37F 707PKE37F None   L33F T12S, L19I, R41K, L63V, H69K, L89M  
707PKE38F 707PKE38F LPV 83   L10LI, T12A, I15V, G16GE, E35D, M36I, R41K, K45R, L63APT, H69K, V82VI, L89M, I93L  
707PKE39F 707PKE39F None    L10V, T12TA, I15IV, L19V, M36I, R41K, L63V, H69K, T74S, L89M, I93L  
707PKE40F 707PKE40F LPV 84   T12TS, I15V, L19IT, M36I, R41K, L63HP, H69K, L89LM, I93L  
707PKE41F 707PKE41F None    T12S, I15V, L19I, M36I, R41K, H69K, L89M, I93L  
707PKE43F 707PKE43F LPV 46   T12TS, K14KR, I15IV, L19IT, M36MI, N37S, R41K, H69K, V82VI, L89M, I93L  
707PKE44F 707PKE44F None    T12S, L19T, K20R, M36I, N37A, L63P, H69K, L89I, I93L  
707PKE49F 707PKE49F LPV 121   T12S, I15V, L19I, K20MR, E35D, M36I, R41K, D60E, Q61E, L63P, H69K, I93L  
707PKE50F 707PKE50F None    T12S, I15V, L19T, M36I, R41K, L63P, H69K, I72IV, I93L  
707PKE51F 707PKE51F LPV 144   I15V, L19V, M36I, R41K, H69K, I93L  
707PKE52F 707PKE52F None    T12S, L19V, M36I, R41K, L63P, H69K, L89M, I93L  

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