Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Balamane (2012)
Title Panel of prototypical recombinant infectious molecular clones resistant to nevirapine, efavirenz, etravirine, and rilpivirine.
Citation AAC
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 10
NumPts 10
Subtype B

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
CA1579 9 DDC, AZT, 3TC, D4T, DDI DLV, NVP M41L, L210W, T215Y E138G, H221Y, F227L, M230L K122E, D177E, I178L, R211K, V245M, I293V  
CA16182 4 AZT, 3TC, D4T, DDI NVP  V106I, Y181C, G190A, H221Y V35I, S68G, A98S, D121E, K122E, I135V, R211K, F214L, V245E, D250E, A272P, E297K  
CA1833 6 AZT, D4T, 3TC, DDC, ABC NVP, EFV M41L, D67N, T69D, L74I, L210W, T215Y A98G, K101E, Y181C, G190A T39E, E44D, V118I, K122E, I135T, G196E, E203K, R211K, A272S, V276T, K277R, Q278E, L283I, I293V, E297K  
CA2100 10 AZT, DDC, D4T, 3TC DLV M41L, D67G, L74I, M184V, T215Y L100I, V179D, M230L V35I, K103R, K122E, I202V, R211K, T240K  
CA25641 2 AZT, 3TC, TDF, DDI EFV, NVP  K101E, E138G, G190S V35M, R211K, V245E, S251I  
CA5244 11 AZT, 3TC, D4T EFV M41L, T215Y K101P, K103N A98S, K102Q, D123E, K166R, D177E, D192N, R211K, V245K, K277R, R284K, T286A, E297K  
CA5375 7 3TC, DDI, D4T, TDF, FTC NVP, DLV M41L, T215D A98G, K101E, E138K, Y181C K122E, I135T, S162Y, T200A, L210F, P243T, V245E, D250E, A272P, I274V, Q278H, K281R, T286A, A288S, K311R  
CA5485 1 DDI, 3TC, D4T, ABC EFV M41L, L74V, M184V, T215Y L100I, K103N, H221Y R83K, D177E, T200A, R211Q, K281R, R284K, I293V, E297A  
CA5735 3 AZT, D4T, 3TC NVP K70R, M184V, T215F K101E, Y181V T27S, E28K, K32E, V60I, T69N, R83K, V179I, T200A, Q207D, L228R, V245E, T286A, E297K  
CA7066 5 3TC, AZT, DDI, ABC, D4T NVP, EFV M41L, T215F K103N, V179F, Y181C K49R, K82R, A98S, D177E, G196E, Q207K, R211A, L228R, A272P, I293V, K311R  

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