Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Hamkar (2010)
Title Assessing subtype and drug-resistance-associated mutations among antiretroviral-treated HIV-infected patients.
Citation AIDS
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 42
NumPts 42
Subtype B, CRF35_AD, A + D, CRF01_AE

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
Ir-HIV-DR-01 NRTI NNRTI K70R, M184V P225H, K238T, N348I K64R, K101N, K104X, T200A, T286A, I293V, T296S, E297K, K311R, E344K, G352R, R356K, M357N, R358E K103D, Y342S, P345K, K350E, T351N 
10 Ir-HIV-DR-10 NRTI NNRTI M41L, D67N, L74V, M184V K101H, E138K, P225H, K238T, N348I M16I, T39A, K43E, E44D, K64R, V111I, V118I, D121E, K122E, D123E, I135T, G141E, T200A, T286A, I293V, T296S, E297K, K311R, E344K, G352R, R356K, M357N, R358E F124S, N137M, T139P, Y342S, P345K, K350E, T351N 
11 Ir-HIV-DR-11 NRTI NNRTI K70R, M184V K103N, P225H V10L, K11R, V35T, K49R, V60I, I135T, S162C, D177E, I178L, V179I, T200I, Q207A, R211K, D250E, A272P, L283I, V292I, I293V, I326X S251K 
12 Ir-HIV-DR-12 NRTI NNRTI K70R, M184V K103N, P225H K11R, V35R, K49R, V60I, I135T, S162C, D177E, I178L, V179I, T200I, Q207A, R211K, D250E, A272P, L283I, V292I, I293V, I326X  
13 Ir-HIV-DR-13 NRTI NNRTI M184V, T215Y, K219R P225H K49R, R83K, D123E, I135L, R143K, I159L, K166R, R172K, K173N, Q174K, D177E, T200S, E204D, K277R, Q278E, I293V, E297K, Q330R, K331T D86T, P95T 
14 Ir-HIV-DR-14 NRTI NNRTI M184V, T215Y G190S E6D, V8I, K11R, V35T, K49R, V60I, D121Y, K122E, S134R, I135T, K166R, Q174H, D177E, V179I, Q207A, R211K, V245E, D250E, A272P, L283I, R284K, A288S, E291D, V292I, I293V, G335D  
15 Ir-HIV-DR-15 NRTI NNRTI M184V, T215Y G190S E6D, V8I, K11R, V35T, K49R, V60I, A98X, K101S, K103E, V106X, D121Y, K122E, I135K, K166R, Q174H, D177E, V179I, Q207A, R211K, V245E, D250E, A272P, L283I, R284K, A288S, E291D, V292I, I293V, G335D  
16 Ir-HIV-DR-16 NRTI NNRTI M184V, T215Y P225H W24*, K43R, G45R, K46E, E53D, R83K, Q91H, K103E, D123E, I135L, I159*, K166R, D177E, T200A, K277R, Q278E, I293V, E297K, Q330R, K331T Q23K, P25H, T27M, E28T, I31N, K49G, E79G, D86T, P95T, T107K 
17 Ir-HIV-DR-17 NRTI NNRTI   V35I, T39K, K43E, Y56F, K122E, D123N, I135X N136H, N137R 
18 Ir-HIV-DR-18 NRTI NNRTI  P225H, K238T V35L, E36D, R83K, L100X, K102Q, K103R, K122P, D177E, T200A, P294S, E297K  
19 Ir-HIV-DR-19 NRTI NNRTI M184V, T215Y G190S E6S, K11R, V35K, V60I, A98X, K101S, K103E, V106X, D121Y, K122E, I135K, K166R, Q174H, D177E, V179I, Q207A, R211K, V245E, D250E, A272P, L283I, R284K, A288S, E291D, V292I, I293V, G335D  
Ir-HIV-DR-02 NRTI NNRTI M184V K103N, E138K, P225H K11R, V35R, V60I, T131X, I135T, S162C, D177E, I178L, V179I, T200I, Q207A, R211K, D250E, A272P, L283I, V292I, I293V, I326M, I341F, F346Y, G352X, A355E, R356K N136L, N137R, T139N 
20 Ir-HIV-DR-20 NRTI NNRTI K70R P225H, K238T K64R, L100X, K122P, D177E, T286A, I293V, T296S, E297K, K311R  
21 Ir-HIV-DR-21 NRTI NNRTI M184V, T215Y G190S E6S, K11R, V35K, V60I, D121Y, K122E, I135T, K166R, Q174H, D177E, V179I, Q207A, R211K, V245E, D250E, A272P, L283I, R284K, A288S, E291D, V292I, I293V, G335D  
22 Ir-HIV-DR-22 NRTI NNRTI K70R, M184V P225H, K238T, N348I K64R, W88C, K101N, K104X, T200A, T286A, I293V, T296S, E297K, K311R, P313R, E344K, G352R, R356K, M357N, R358E V10K, G51A, E89Q, K103D, G152P, P247R, Y342S, P345K, K350E, T351N 
23 Ir-HIV-DR-23 NRTI NNRTI M41L, V75M, L210W, T215Y Y181C, G190A, P225H, K238T S68G, T69A, L100X, K101Q, K122E, I135T, I142V, T286A, I293V, T296S, E297K, K311R D320L 
24 Ir-HIV-DR-24 NRTI NNRTI   K11R, V35T, T39A, V60I, D121Y, K122E, S162N, D177E, V179I, Q207A, R211K, W239WGR, D250E, A272P, L283I, V292I, I293V, I326X  
25 Ir-HIV-DR-25 NRTI NNRTI   E6D, V8I, K11R, V35T, K49R, V60I, D121Y, K122E  
26 Ir-HIV-DR-26 NRTI NNRTI M41L, T69DN  E44D, A98S, V118I, I142V  
27 Ir-HIV-DR-27 NRTI NNRTI M41L K103N, V108I T39A, K102Q, D123E, I142V, S162Y  
28 Ir-HIV-DR-28 NRTI NNRTI   K11R, V35T, T39I, V60I, D113DG, D121Y, K122E, T165I, V179I, G196K, T200I, Q207A, R211K, D250E, A272P, L283I, V292I, I293V, I326X  
29 Ir-HIV-DR-29 NRTI NNRTI M41L, D67N, K70R  K20R, V21I, K32T, T39K, V60I, K122E  
Ir-HIV-DR-03 NRTI NNRTI K70R, M184V K103N, P225H K11R, V35T, K49R, V60I, I135T, S162C, D177E, I178L, V179I, T200I, Q207A, R211K, D250E, A272P, L283I, V292I, I293V, I326X  
30 Ir-HIV-DR-30 NRTI NNRTI   V35I, T39K, K43E, K122E, D123N, I135X N136H, N137R 
31 Ir-HIV-DR-31 NRTI NNRTI   K11R, V35T, V60I, D121Y, K122E, D177E, V179I, T200R, Q207A, R211K, D250E, A272P, L283I, V292I, I293V, I326X  
32 Ir-HIV-DR-32 NRTI NNRTI M41L, D67N, K70R K103KN, V108VI K20R, K32KT, V35VI, T39K, V60VI, S68SG, K122KE  
33 Ir-HIV-DR-33 NRTI NNRTI K70R, M184V P225H, K238T, N348I S48L, K64R, D86N, K101N, K104X, S134N, Q174H, T200A, T286A, I293V, T296S, E297K, K311R, E312Q, E344K, G352R, R356K, M357N, R358E D76H, K103D, W252C, Y342S, P345K, K350E, T351N 
34 Ir-HIV-DR-34 NRTI NNRTI   K11R, V35T, V60I, D121Y, K122E, D123E, T165I, D177E, V179I, Q207A, R211K, D250E, A272P, L283I, V292I, I293V, I326X  
35 Ir-HIV-DR-35 NRTI NNRTI   K11R, V35T, V60I, D121Y, K122E, D177E, V179I, T200R, Q207A, R211K, D250E, A272P, L283I, V292I, I293V, I326X, K331N Q332A 
36 Ir-HIV-DR-36 NRTI NNRTI K70R, M184V P225H, K238T, N348I K64R, K101N, K104X, T200A, R211K, T286A, I293V, T296S, E297K, K311R, E344K, G352R, R356K, M357N, R358E W71G, K103D, L149F, Y342S, P345K, K350E, T351N 
37 Ir-HIV-DR-37 NRTI NNRTI M184V K103N, E138K, P225H K11R, V35R, V60I, T131X, I135T, S162C, D177E, I178L, V179I, T200I, Q207A, R211K, L228F, D250E, A272P, L283I, V292I, I293V, E308G, I309V, I326M, Q336P, I341F, F346Y, G352X, A355E, R356K P14G, N136L, N137R, T139N, V254F 
38 Ir-HIV-DR-38 NRTI NNRTI M184V K103N, E138K, P225H K11R, V35R, V60I, T131X, I135T, S162C, D177E, I178L, V179I, T200I, Q207A, R211K, D250E, A272P, L283I, V292I, I293V, I326M, I341F, Y342F, F346Y, G352X, A355E, R356K G15P, K126G, N136L, N137R, T139N 
39 Ir-HIV-DR-39 NRTI NNRTI K70R, M184V P225H, K238T, N348I E29K, K64R, K101N, K104X, S191F, T200A, T286A, I293V, T296S, E297K, E312K, E344K, G352R, R356K, M357N, R358E P52G, K103D, A114G, G213V, Y342S, P345K, K350E, T351N 
Ir-HIV-DR-04 NRTI NNRTI K70R, M184V P225H, K238T, N348I K64R, K101N, K104X, T200A, T286A, I293V, T296S, E297K, K311R, E344K, G352R, R356K, M357N, R358E K103D, Y342S, P345K, K350E, T351N 
40 Ir-HIV-DR-40 NRTI NNRTI   E6S, K11R, V35K, V60I, D121Y, K122E, I135T  
41 Ir-HIV-DR-41 NRTI NNRTI K70R, M184V P225H, K238T, N348I A33G, I50F, K64R, V90I, K101N, K104X, G112A, K173R, T200A, R211K, T286A, I293V, T296S, E297K, K311R, Q336K, E344K, G352R, R356K, M357N, R358E K73N, K103D, V276K, Y342S, P345K, K350E, T351N 
42 Ir-HIV-DR-42 NRTI NNRTI M184V K103N, E138K, P225H K11R, V35R, V60I, T131X, I135T, S162C, D177E, I178L, V179I, Q197P, T200I, Q207A, R211K, D250E, A272P, L283I, V292I, I293V, E302G, I326M, I341F, F346Y, G352X, A355E, R356K N136L, N137R, T139N, W252S 
Ir-HIV-DR-05 NRTI NNRTI M41L, D67N, L74I, M184V, L210W, T215Y V106A, V108I, G190A, F227L V35K, T39A, K43E, V60I, A98S, K104X, V118I, K122E, I135T, E138X, T200A, I202V, E203K, K223E, Q278H, A288S, L310V, E312V, V314G, G316R, Y318N N137E, V317N 
Ir-HIV-DR-06 NRTI NNRTI K70R, M184V K103N, E138K, P225H V35R, V60I, K104X, I135T, S162C, D177E, I178L, V179I, T200I, Q207A, R211K, D250E, A272P, L283I, V292I, I293V, I326M, I341F, F346Y, G352X, A355E, R356K Y127V, T128N, A129C, F130I, T131H, N136L, N137R, T139N 
Ir-HIV-DR-07 NRTI NNRTI K70R, M184V K103N, P225H K11R, V35R, K49R, V60I, I135T, S162C, D177E, I178L, V179I, T200I, Q207A, R211K, D250E, A272P, L283I, V292I, I293V, I326X  
Ir-HIV-DR-08 NRTI NNRTI M184V K103N, E138K, P225H K11R, V35R, V60I, T131X, I135T, S162C, D177E, I178L, V179I, T200I, Q207A, R211K, D250E, A272P, L283I, V292I, I293V, I326M, I341F, F346Y, G352X, A355E, R356K N136L, N137R, T139N 
Ir-HIV-DR-09 NRTI NNRTI K70R, M184V K103N, E138K, P225H V35R, V60I, K104X, F124L, I135T, S162C, D177E, I178L, V179I, T200I, Q207A, R211K, D250E, A272P, L283I, V292I, I293V, I326M, I341F, F346Y, G352X, A355E, R356K R125E, N136L, N137R, T139N