Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Cardoso (2009)
Title High level of multidrug resistance mutations in HIV type 1 pol gene and resistance-associated mutations to enfuvirtide (T-20) among antiretroviral-experienced patients from central Brazil.
Citation ARHR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 48
NumPts 48
Subtype B, F, C, B + F, CRF05_DF

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
3000 BRGO3000 NRTI NNRTI   D121H, D177E, I178IV, Q207E, R211RK  
3006 BRGO3006 NRTI NNRTI M41L, M184V, L210W  T39A, K122E, D123N, I135V, I142V, R211K, D237E  
3014 BRGO3014 NRTI NNRTI M184V K103N, P225H S48T, K122E, D123N  
3020 BRGO3020 NRTI NNRTI M184V  R83K, S162X, G196E, T200IR, Q207QH, R211RG  
3023 BRGO3023 NRTI NNRTI D67N, K70R, M184V, T215F, K219Q K103S, V106I, Y181C, G190A, H221Y K20R, V35M, T69TN, K101Q, V118I, I135T, K166R, D177E, I202IV, H208HY, R211K, F214L  
3025 BRGO3025 NRTI NNRTI   K11R, D123E, I135T, I178L, I202IV, R211K  
3031 BRGO3031 NRTI NNRTI M41L, M184V, L210W, T215Y K103N, V108I, K238T K20R, T39A, K43Q, K122E, I135T, D177E, V245K  
3035 BRGO3035 NRTI NNRTI   V35I, S68G, K122E, I135T, D177E, I178M, T200A, Q207E, R211K  
3039 BRGO3039 NRTI NNRTI D67N, K70R, L74I, M184V, T215F, K219Q V106VA, G190AV V35L, K43R, T69N, K101Q, K122E, D123S, Q174K, N175Y, R211A  
3047 BRGO3047 NRTI NNRTI M184V, K219R K103N, P225H K20R, V35T, T39L, V60I, K102R, I135V, D177DE, I178M, T200A, Q207E, R211K, F214L, L228H  
3055 BRGO3055 NRTI NNRTI M41L, D67N, M184V, T215Y K101E, V106I, G190S P4S, V21I, E28K, K32E, V35M, I135T, S162C, D177E, I178M, T200A, R211KQ  
3060 BRGO3060 NRTI NNRTI K70R, M184V K103N, P225H T39A, K43Q, T69N, A98S, K122E, D123S, I142V, S162Y, V179I, T200A, R211K  
3062 BRGO3062 NRTI NNRTI M184V E138EK V35T, K49R, K122E, D123G, I135T, S162C, E169D, K173A, Q174K, I178L, Q207A, R211K  
3064 BRGO3064 NRTI NNRTI M184V K103N, V108I K102Q, K122E, I135T, D177E, D237E K20I 
3067 BRGO3067 NRTI NNRTI M41L, L210W, T215Y A98G, G190A V35L, T39A, K43E, D121Y, K122E, P176Q, V179I, T200A, I202V, E203D, V245K  
3071 BRGO3071 NRTI NNRTI  K103N V21I, K122Q, I195L, G196E E233A, H235Q 
3080 BRGO3080 NRTI NNRTI M41L, D67N, M184V, L210W, T215Y K101E, K103N, G190A K32N, T39A, E44D, V118I, K122E, D123N, I135K, S162C, D192N, R211K  
3082 BRGO3082 NRTI NNRTI M184V K103N V35T, K49R, D123E, I135T, S162C, E169K, K173E, Q174K, I178L, T200K  
3085 BRGO3085 NRTI NNRTI M41L, L74I, M184V  K20R, K122E, I135T, E169D D186Y 
3089 BRGO3089 NRTI NNRTI T215D  V21VI, V35T, I135T, S162C, G196E, Q197P, R211K  
3090 BRGO3090 NRTI NNRTI M184V K103N, P225H K20R, D123E, I135T, S162C, D177E, R211K  
3092 BRGO3092 NRTI NNRTI M184V K103N K122E, I135T, S162C, E169D, D177E, I178M, T200K, Q207E, L210F  
3095 BRGO3095 NRTI NNRTI M41L, T69S_KG, L74V, L210W, T215F, K219E L100I, K103N V60I, D67A, S68G, A98S, V118I, K122E, I135T, S162H, D177N, G196E, T200A, I202V K64Q 
3096 BRGO3096 NRTI NNRTI M41L, D67DN, L74I, M184V, L210W K103N, V108I K43Q, V60VI, V118I, K122E, I135T, T200S  
3097 BRGO3097 NRTI NNRTI M184V K103N, P225H R83K, I135L, S162C, G196E, R211G  
3098 BRGO3098 NRTI NNRTI   V35T, T39E, S48T, K122E, D123S, I135R, K173A, Q174R, T200A, Q207D  
3102 BRGO3102 NRTI NNRTI D67N, K70R, V75M, M184V, T215V, K219Q L100I, K103N, H221HY K20R, T27S, K46Q, V60I, T69N, K104R, K122E, I135T, D177N, I202V, H208HY, R211K, L228H  
3106 BRGO3106 NRTI NNRTI   K104N, D123E, I135T, S162C, D177E, T200A, R211K  
3107 BRGO3107 NRTI NNRTI M41L, L74V, M184V, T215Y K101E, V108I, E138A, Y181C, G190A, H221Y K20R, K32Q, K122E, V245T  
3108 BRGO3108 NRTI NNRTI M41L, A62V, D67N, V75I, M184V G190A V35T, K122E, D123S, I135T, S162C, D177E, T200S  
3110 BRGO3110 NRTI NNRTI M184V E138Q, Y181C I31L, V35L, T39A, E44D, K102KR, V111I, K122E, D123N, I135T, S162C, I178L, V179I P1A 
3113 BRGO3113 NRTI NNRTI   P4S, K20R, D123E, I135T, E169D, D177E, I178L, T200V, I202V, R211K, F214L  
3114 BRGO3114 NRTI NNRTI D67N, T69D, K70R, L74V, M184V, T215F, K219Q L100I, K103N A98S, K122E, S162C, Q174H, D177N, T200A, Q207E, D218E, L228H  
3115 BRGO3115 NRTI NNRTI M41L, M184V, L210W, T215Y  K43N, I135T, Q242L  
3117 BRGO3117 NRTI NNRTI D67N, K70R, M184V K103N K32R, D121Y, K122E, D123E, I135M, D177E, V179I, T200A, R211K  
3119 BRGO3119 NRTI NNRTI   K20R, D67DA, K102Q, K104R, D121CY, K122E, T165I, I178L, G196E, F214L R78RS, D86DA 
3124 BRGO3124 NRTI NNRTI M41L, D67N, K70R, V75M, M184V, L210W, T215Y, K219E K103S, G190A E28K, K32E, V60I, K122E, K173Q, R211K, Q222R  
3125 BRGO3125 NRTI NNRTI M41L, T215Y A98G, K103N, Y181C, G190A K32N, K122E, D123E, I135K, I178L, R211K  
3127 BRGO3127 NRTI NNRTI M184V K103N, E138A K101Q, I135L, T200A, Q207D, R211K  
3128 BRGO3128 NRTI NNRTI M184V K103N V21I, V60I, I135T, K173N, Q174R, N175H, T200A, I202V, Q207E, R211A  
3131 BRGO3131 NRTI NNRTI D67N, K70R, V75M, M184V, T215F, K219E K103N K73M, V90I, I94L, I135T, S162A, D177N, G196E, E203A, Q207E, H208Y, R211K, L228H R125RQ 
3132 BRGO3132 NRTI NNRTI   K32R, V35I, R83K, D123E, I135T, I178M  
3138 BRGO3138 NRTI NNRTI M41L, D67N, K70R, V75M, M184V K103N, V108I, G190A V35T, T39A, V60I, K102Q, D123E, I135T, D177E, T200I  
3139 BRGO3139 NRTI NNRTI M184V K103N, P225H K20R, K32R, A158S, S163ST, K173T, Q207E, R211K  
3144 BRGO3144 NRTI NNRTI M41L, D67N, T69D, L74I, V75T, M184V, T215F, K219Q Y181C V118I, K122E, D123E, I135T, S162SN, G196E, F214L, D218E, L228H  
3145 BRGO3145 NRTI NNRTI   K20R, V35T, T39S, K122E, I178L  
3153 BRGO3153 NRTI NNRTI M41L, M184V, T215Y K103N, V106M K20R, K30R, E44D, D121H, K122E, D123E, D177E, I178L, R211T  
3154 BRGO3154 NRTI NNRTI M41L, D67N, M184V, T215Y  K122E, I135T, S162C, R211T  

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