Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Isarangkura-Na-Ayuthaya (2010)
Title Appearance of drug resistance-associated mutations in human immunodeficiency virus type 1 CRF01_AE integrase derived from drug-naive Thai patients.
Citation ARHR
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 78
NumPts 78
Subtype CRF01_AE, B

 

Clinical IN Isolates


SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
AE-Int-104 AE-Int-104 None    K14R, A21T, V31I, T112V, T124A, T125A, G134N, K136Q, D167E, V201I, L234I, S283G  
AE-Int-105 AE-Int-105 None    K14R, A21T, V31I, S39N, I72V, T112V, T124N, T125A, V126M, G134N, I135V, K136Q, V165I, D167E, V201I, L234I, S283G  
AE-Int-107 AE-Int-107 None    K14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, D167E, V201I, L234I, S283G  
AE-Int-111 AE-Int-111 None    K14R, V31I, I72V, T112V, S119P, T124A, T125A, V126M, G134N, I135V, D167E, V201I, T206S, D207E, K211R, L234I, D256E, S283G  
AE-Int-114 AE-Int-114 None    K14R, A21AT, V31I, I72V, T112V, T124A, T125A, G134N, I135V, K136R, M154I, D167E, V201I, Q216H, L234I, S283G  
AE-Int-119 AE-Int-119 None    E13D, K14R, A21T, A23AV, S39N, I60V, I72V, Y99L, T112V, T124A, T125A, G134N, I135V, K136R, D167E, I208M, L234I, D256E, S283G  
AE-Int-12 AE-Int-12 None    K14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283G  
AE-Int-121 AE-Int-121 None    K14R, V31I, L101I, T112V, T124A, T125A, G134N, I135V, K136Q, D167E, V201I, T218S, L234I, S283G  
AE-Int-128 AE-Int-128 None    E11D, K14R, A21T, A23V, V31I, I72V, T112V, T124A, T125A, V126M, G134N, I135V, K136R, D167E, V201I, T218P, L234I, S283G, D286E, D288E  
AE-Int-129 AE-Int-129 None    K14R, A21T, S39N, L45V, I72V, T112V, T124A, T125A, G134N, I135V, K160Q, Q164K, D167E, R187K, V201I, L234I, S283G  
AE-Int-13 AE-Int-13 None    E11D, A21T, A23V, L101V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283G, R284G  
AE-Int-130 AE-Int-130 None    K14R, A21T, V31I, S39N, I72V, T112V, T124N, T125A, G134N, I135V, K136Q, D167E, V201I, L234I, S283G  
AE-Int-133 AE-Int-133 None    D6E, E11D, V31I, L45Q, I72V, T112V, T124A, T125A, G134N, I135V, K136Q, D167E, R187K, V201I, L234I, D253E, S283G  
AE-Int-134 AE-Int-134 None    K14R, V31I, V32I, I72V, L101I, T112V, T124A, T125A, G134N, I135V, K136Q, D167E, V201I, L234I, S283G  
AE-Int-135 AE-Int-135 None    E11D, K14R, A21T, A23V, V31I, I72V, L101I, T112V, T125A, G134N, I135V, K136Q, D167E, V201I, L234I, S283G  
AE-Int-14 AE-Int-14 None    E11D, A21T, V31I, S39N, I72V, T112V, T125A, G134N, I135V, K136R, D167E, V201I, I203M, T218S, L234I, D253E, S283G  
AE-Int-140 AE-Int-140 None    K14R, A21T, V31I, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283G, R284G  
AE-Int-143 AE-Int-143 None    E11D, A21T, V31I, S39N, I72V, T112V, T125A, G134N, I135V, K136R, V165I, D167E, V201I, L234I, S283G  
AE-Int-153 AE-Int-153 None    K14R, V32I, I72V, T112V, T124A, T125A, G134N, I135V, K136Q, V165I, V201I, L234I, S283G  
AE-Int-156 AE-Int-156 None    K14R, A21T, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283G  
AE-Int-158 AE-Int-158 None    E11D, K14R, A21T, V31I, I72V, T112V, T124S, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283G  
AE-Int-159 AE-Int-159 None    K14R, A21T, V31I, S39N, I72V, T112V, T124Q, T125A, V126M, K127R, G134N, I135V, K136Q, D167E, V201I, T218S, L234I, S283G  
AE-Int-162 AE-Int-162 None    E11D, K14KR, A21T, V31I, I72V, T112V, T124N, T125A, G134N, I135V, M154L, V165I, D167E, V201I, L234I, D256E, S283G  
AE-Int-164 AE-Int-164 None    K14R, S17T, A21T, M22I, L28M, V31I, V32I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, S153A, D167E, V201I, L234I, S283G  
AE-Int-17 AE-Int-17 None    E11D, K14R, A21T, V31I, S39N, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283G  
AE-Int-19 AE-Int-19 None    K14R, A21T, V31I, I72V, T112V, T124A, T125A, G134N, I135V, K136H, V201I, L234I, S283G, D286N  
AE-Int-23 AE-Int-23 None    K14R, A21T, V31I, I72V, T112V, T124A, T125A, G134N, I135V, K136R, V165I, I200M, V201I, I203M, L234I, S283G  
AE-Int-25 AE-Int-25 None    K14R, A21T, V31I, I72V, L101I, T112V, T124A, G134N, I135V, K136R, K160Q, Q164K, D167E, V201I, L234I, S283G, R284G  
AE-Int-265 AE-Int-265 None    K14R, A21T, V31I, S39N, I72V, T112V, T125A, V126L, G134N, I135V, V201I, L234I, S283G  
AE-Int-267 AE-Int-267 None    E11ED, K14R, A21T, V31I, I72V, T112V, T124A, T125A, G134N, I135V, K136Q, D167E, V201I, L234I, S283G, D288E  
AE-Int-271 AE-Int-271 None    E11D, K14R, A21T, V31VI, L63V, I72V, I84L, T112V, I113V, T125A, G134N, K136Q, V201I, I203M, L234I  
AE-Int-272 AE-Int-272 None    K14R, A21T, S39N, L45V, I72V, T112V, I113V, T124A, T125A, G134D, K136R, V165I, D167E, V201I, L234I, D256E, S283G  
AE-Int-273 AE-Int-273 None    K14R, A21T, V31I, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283G  
AE-Int-274 AE-Int-274 None    K14R, A21T, V31I, S39N, I72V, Y83F, T112A, T124A, T125A, V126F, G134N, I135V, K136Q, V165I, D167E, R187K, V201I, L234I, S283G  
AE-Int-276 AE-Int-276 None    E11D, K14R, A21T, V31I, I72V, T112V, T125A, G134N, I135V, K136R, D167E, V201I, I208L, L234I, D278E, S283G  
AE-Int-280 AE-Int-280 None    K14R, S24N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, T218S, I220L, L234I, S283G  
AE-Int-281 AE-Int-281 None   T97A K14R, A21T, V31VI, M50I, I72V, T112V, T124A, T125A, G134N, K136Q, V201I, K211R, L234I M154K 
AE-Int-282 AE-Int-282 None    K14R, A21T, V31I, I72V, T112V, T124N, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283G  
AE-Int-284 AE-Int-284 None    K14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, L234I, S283G V201M 
AE-Int-287 AE-Int-287 None    E11D, K14R, A21T, S24G, D25E, V31VI, E35Q, S39N, I72V, L101I, T112V, T125A, G134N, I135V, K136Q, D167E, V201I, L234I, S283G, D288E  
AE-Int-288 AE-Int-288 None    K14R, A21T, V31I, S39N, I72V, T112V, T124N, T125A, G134N, I135V, K136Q, D167E, V201I, L234I, S283G  
AE-Int-293 AE-Int-293 None    K14R, V32I, I72V, T112V, T124N, T125A, G134N, I135V, K136R, D167E, V201I, K211R, L234I, S283G  
AE-Int-295 AE-Int-295 None    K14R, A21T, V31I, S39SN, I72V, T112V, T124A, T125A, G134N, I135V, K136KR, V165I, D167E, R187K, V201I, T206S, K211R, S230N, L234I, S283G  
AE-Int-300 AE-Int-300 None    K14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, V126L, I135V, D167E, K188R, V201I, I203M, L234I, S283G  
AE-Int-308 AE-Int-308 None    K14R, V31I, S39N, I72V, L101I, T112V, T124N, T125A, G134N, I135V, K136R, V165I, D167E, G193E, V201I, I203M, L234I, S283G, D286N  
AE-Int-347 AE-Int-347 None    E11D, K14R, A21T, A23V, V31I, I72V, L101I, T112V, I113V, T124A, T125A, K136N, D167E, V201I, L234V, S283G, D288E  
AE-Int-349 AE-Int-349 None    E11D, K14R, A21T, V31I, V32I, I72V, T112V, T124A, T125A, G134N, K136Q, I161IV, D167E, V201I, K211R, L234I, D270E, S283G  
AE-Int-353 AE-Int-353 None    E11D, R20RK, A21T, D25E, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, G193D, I203IM, L234I, S283G  
AE-Int-355 AE-Int-355 None    E11D, K14R, A21T, V32I, I72V, T112V, T125A, V126M, G134N, I135V, K136R, V165I, D167E, V201I, L234I, S283G  
AE-Int-357 AE-Int-357 None    K14R, A21T, V31VI, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, V165I, D167E, V201I, L234I, S283G  
AE-Int-359 AE-Int-359 None    K14R, V32I, I72V, L101I, T112V, T124A, T125A, K127R, G134N, I135V, K136R, D167E, V201I, L234I, S283G  
AE-Int-367 AE-Int-367 None    E11ED, K14R, A21T, V31I, S39N, L45V, I72V, T112V, T124A, T125A, G134N, I135V, K136Q, D167E, V201I, L234I, D256E, D288E  
AE-Int-370 AE-Int-370 None    E11D, K14R, A21T, V31I, I72V, T112V, T124A, T125A, G134N, I135V, V165I, D167E, V201I, K215N, L234I, S283G  
AE-Int-371 AE-Int-371 None    K14R, A21T, I72V, L101I, T112V, T124A, G134N, I135V, K136R, V165I, D167E, V201I, L234I, S283G  
AE-Int-373 AE-Int-373 None    K14R, A21T, V31I, I72V, T112V, T124A, T125A, G134N, I135V, K136QR, K160R, D167E, V201I, L234I, S283G, D288E  
AE-Int-381 AE-Int-381 None    K14R, A21T, S39N, L45V, I72V, T112V, I113V, T124A, T125A, G134S, K136H, V165I, V201I, I203M, L234I, D256E, S283G  
AE-Int-382 AE-Int-382 None    K14R, V31I, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136Q, K160T, D167E, V201I, L234I, S283G, D286E, D288E  
AE-Int-385 AE-Int-385 None    V31I, S39N, I72V, T112V, T124N, T125A, G134N, I135V, K136Q, V165I, D167E, V201I, I203M, L234I, S283G  
AE-Int-392 AE-Int-392 None    K14R, A21T, V31I, I72V, T112V, T124A, T125A, V126VM, G134N, I135V, K136R, D167E, V201I, L234I, S283G, D286E, D288E  
AE-Int-393 AE-Int-393 None    K14R, A21T, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I, Q252R, S283G L242V 
AE-Int-398 AE-Int-398 None    K14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, V126M, G134N, I135V, K136R, D167E, V201I, L234I, S283G  
AE-Int-403 AE-Int-403 None    E11D, K14R, A21T, V31I, V32I, I72V, Q95H, T112V, T125A, G134N, K136Q, D167E, V201I, L234I, D286E, D288E  
AE-Int-42 AE-Int-42 None    K14R, V31VI, I72V, Q95H, T112V, T124A, T125A, G134N, K136Q, V201I, L234I, S283G  
AE-Int-61 AE-Int-61 None    K14R, A21T, V31I, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283G  
AE-Int-65 AE-Int-65 None    E11D, K14R, A21T, A23V, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136Q, V165I, D167E, V201I, L234I, S283G  
AE-Int-67 AE-Int-67 None    K14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136Q, V165I, D167E, V201I, L234I, S283G  
AE-Int-68 AE-Int-68 None    E11D, A21T, V31I, I72V, T112V, T124A, T125A, V126M, G134N, I135V, K136Q, D167E, V201I, L234I, S283G  
AE-Int-69 AE-Int-69 None    K14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283G  
AE-Int-76 AE-Int-76 None    K14R, A21T, V31I, S39N, I72V, T112V, T124A, T125A, G134N, I135V, K136R, V165I, D167E, V201I, L234I, S283G  
AE-Int-79 AE-Int-79 None    K14R, V31I, S39SN, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136Q, I141V, D167E, V201I, L234I  
AE-Int-81 AE-Int-81 None    K14R, A21T, V31I, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136R, D167E, V201I, L234I, S283G  
AE-Int-83 AE-Int-83 None    K14R, S17N, A23AV, L101I, T112IV, T124A, T125A, G134N, I135V, K136Q, V201I, L234I, S283G  
AE-Int-91 AE-Int-91 None    K14R, A21T, V31I, I72V, Q95H, T112V, T124A, T125A, G134N, I135V, K136R, Q164K, V201I, L234I, S283G R187N 
AE-Int-95 AE-Int-95 None    E11D, K14R, A21T, V31I, M50I, L63V, I72V, I84L, T112V, T124A, T125A, G134N, I135V, K136R, V165I, I200M, V201I, I203M, L234I, S283G  
AE-Int-98 AE-Int-98 None    K14R, S17N, V31I, I72V, T112V, T124A, T125A, G134N, I135V, K136R, D167E, K173R, G193D, S195C, V201I, L234I, S283G  
B-Int-112 B-Int-112 None    V31I, L45V, L101I, S119P, G163E, V201I, L234I, S283G  
B-Int-298 B-Int-298 None    E11D, K14R, A21T, L101I, T125A, A196P, L234V, D288E D286K 
B-Int-40 B-Int-40 None    V31I, L45V, L101I, S119P, G163E, V201I, L234I, S283G  

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