Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Nijhuis (2009)
Title Failure of treatment with first-line lopinavir boosted with ritonavir can be explained by novel resistance pathways with protease mutation 76V.
Citation J Infect Dis
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 9
NumPts 3
Subtype B, K


Clinical PR Isolates

B1 None    E35ED  
  B2 LPV 134 M46MI, L76LV, V82VA  L10LI, E35D, R41RK  
  B3 LPV 139 M46MI, I54IV, L76LV, V82VA  E35D, R41RK  
K1 None      
  K2 LPV 100 M46MI, L76V L33F Q61QH, L63V  
  K3 LPV 135 M46I, L76V, V82A L33F, Q58QE E35D, Q61QH, L63V  
M1 None    K45KR, H69HY  
  M3 LPV 126 M46I, L76V  I13V, E21EG, N37D, Q92K  
  M4 LPV 148 M46I, L76V  I13V, N37D, Q61QR, Q92EK