Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Nijhuis (2009)
Title Failure of treatment with first-line lopinavir boosted with ritonavir can be explained by novel resistance pathways with protease mutation 76V.
Citation J Infect Dis
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 9
NumPts 3
Subtype B, K

 

Clinical PR Isolates


SubjectIsolatePIsWksPIMajorPIMinorCommonUnusual
B B1 None    E35ED  
  B2 LPV 134 M46MI, L76LV, V82VA  L10LI, E35D, R41RK  
  B3 LPV 139 M46MI, I54IV, L76LV, V82VA  E35D, R41RK  
K K1 None      
  K2 LPV 100 M46MI, L76V L33F Q61QH, L63V  
  K3 LPV 135 M46I, L76V, V82A L33F, Q58QE E35D, Q61QH, L63V  
M M1 None    K45KR, H69HY  
  M3 LPV 126 M46I, L76V  I13V, E21EG, N37D, Q92K  
  M4 LPV 148 M46I, L76V  I13V, N37D, Q61QR, Q92EK  

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