Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Koyalta (2009)
Title High frequency of antiretroviral drug resistance among HIV-infected adults receiving first-line highly active antiretroviral therapy in N'Djamena, Chad.
Citation Clin Infect Dis
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 33
NumPts 33
Subtype CRF11_cpx, CRF02_AG, CRF45_cpx, D, G, F, A, B, CRF01_AE, CRF06_cpx

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
TCHAD-1 3TC, D4T NVP M184V, T215F K101E, Y181C, G190A T69A, I135T, S162C, D177E, T200E, I202V, Q207K, R211K  
10 TCHAD-10 3TC, D4T NVP   D123E, A158S, S162F, K173T, Q174K, V179I, T200A, Q207D, R211K  
17 TCHAD-17 3TC, D4T None M184V  V60I, D123E, I135V, K173A, Q174A, D177E, I178L, V179I, Q207E, R211K  
19 TCHAD-19 3TC, D4T NVP M184V G190A D121Y, K122E, D123G, S162A, K173T, Q174K, D177E, Q207A, R211N  
26 TCHAD-26 3TC, D4T NVP M184V K103N K49R, K122E, D123T, T139A, S162C, K173A, D177E, T200E, I202V, Q207K  
28 TCHAD-28 3TC, D4T NVP M184V K103N, V108I K82R, D121H, K122E, S162C, K173S, Q174K, D177E, I178L, T200A, Q207D, R211K, L228Q  
30 TCHAD-30 3TC, D4T NVP   K49R, E53D, V60I, K122A, D123N, D177E, I178L, T200A, Q207E, R211K, F214L  
33 TCHAD-33 3TC, D4T None M184V  D123N, I135V, Q174K, D177E, T200A, I202V, Q207D, R211K, F214L  
35 TCHAD-35 3TC, D4T NVP   K43E, D121H, K122E, D123S, K173A, Q174K, D177E, Q207A, R211S, K238R  
39 TCHAD-39 3TC, D4T None  V106I K49R, V60I, K122E, D123N, S162C, D177E, I178L, Q207E, R211K, F214L  
TCHAD-4 3TC, D4T NVP   E53D, D123E, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207D  
40 TCHAD-40 3TC, D4T NVP  V106I V60I, K122E, D123E, I135V, S162C, Q174H, D177E, T200I, Q207E, R211K, K223R  
47 TCHAD-47 3TC, D4T NVP M184V K103N, G190A K101Q, K122E, D123N, S162T, Q174N, D177E, T200E, Q207K  
48 TCHAD-48 3TC, D4T None M184V  V60I, D123E, I135L, K173Q, Q174K, D177E, I195L, T200A, Q207E, R211K  
53 TCHAD-53 3TC, D4T NVP  Y181C A98S, K122E, D123S, S134R, Y144F, V148G, S162C, K173R, Q174K, D177E, I178L, T200A, E203D, Q207E, R211S I135G 
54 TCHAD-54 3TC, D4T NVP M184V K103N A98S, D123S, I135V, T139R, S162C, K173R, Q174K, D177E, I178L, T200A, E203D, Q207E, R211S  
58 TCHAD-58 3TC, D4T NVP M184V K103S, G190A K122E, D123N, S162F, Q174H, D177E, T200E, I202V, Q207E, R211K L109P 
59 TCHAD-59 3TC, D4T NVP   D123E, I142V, E169A, K173A, Q174K, D177E, Q207A, R211K  
64 TCHAD-64 3TC, D4T NVP M184V A98G, K103N K49R, I135M, S162A, K173T, Q174K, D177E, T200A, Q207E  
66 TCHAD-66 3TC, D4T NVP   K122E, D123G, I135T, K173T, D177E, T200E, I202V, Q207E  
67 TCHAD-67 3TC, D4T NVP D67N, M184V, T215F K101E, G190S K43E, D121H, K122E, D123S, I135T, K173A, Q174K, D177E, V179I, T200A, Q207A, R211S, K238R  
68 TCHAD-68 3TC, D4T None   K49R, V60I, V118I, I135T, I142T, R172K, D177E, I178L, Q207E, F214L  
69 TCHAD-69 3TC, D4T NVP M184V Y181C V60I, A98S, K101R, D121H, K122E, E169D, Q174E, D177E, T200A, Q207E  
70 TCHAD-70 3TC, D4T None M184V  K122E, I135T, S162C, Q174N, D177E, I178L, T200K, I202V, Q207E  
71 TCHAD-71 3TC, D4T NVP   K49R, V60I, K122E, I135T, D177E, I178V, Q197E, T200A, E204K, Q207E, F214L  
72 TCHAD-72 3TC, D4T NVP   K122E, D123N, I135T, S162C, Q174H, D177E, T200E, I202V, Q207N, R211K  
74 TCHAD-74 3TC, D4T NVP M184I K103N, Y181C K49R, V60I, D123E, E169D, K173A, Q174K, D177E, I178M, G196E, Q207E, R211K  
75 TCHAD-75 3TC, D4T NVP M184V, T215F V108I, Y181C K49R, V60I, V90I, I135T, S162H, K173T, Q174K, T200A, Q207E  
76 TCHAD-76 3TC, D4T NVP   K49R, V60I, K122E, D123S, S162C, Q174D, D177E, I178M, G196E, T200E, Q207K  
78 TCHAD-78 3TC, D4T None   K122E, D123N, I135V, S162C, K173T, Q174R, D177E, I178L, T200A, Q207N, R211K  
TCHAD-8 3TC, D4T None D67N, K70R, M184V, K219E V106I V60I, V118I, T139S, T165I, D177E, I178L, K201R, E204K, Q207E, R211K, F214L  
80 TCHAD-80 3TC, D4T NVP   K49R, V60I, R83G, E89K, K104R, K122E, D123N, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E L92T 
85 TCHAD-85 3TC, D4T NVP M184I K103N, Y181C K49R, V60I, D123E, E169D, K173A, Q174K, D177E, I178M, G196E, Q207E, R211K