Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Koyalta (2009)
Title High frequency of antiretroviral drug resistance among HIV-infected adults receiving first-line highly active antiretroviral therapy in N'Djamena, Chad.
Citation Clin Infect Dis
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 33
NumPts 33
Subtype CRF11_cpx, CRF02_AG, CRF45_cpx, D, G, F, A, B, CRF01_AE, CRF06_cpx


Clinical RT Isolates

SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
TCHAD-1 3TC, D4T NVP M184V, T215F K101E, Y181C, G190A T69A, I135T, S162C, D177E, T200E, I202V, Q207K, R211K  
10 TCHAD-10 3TC, D4T NVP   D123E, A158S, S162F, K173T, Q174K, V179I, T200A, Q207D, R211K  
17 TCHAD-17 3TC, D4T None M184V  V60I, D123E, I135V, K173A, Q174A, D177E, I178L, V179I, Q207E, R211K  
19 TCHAD-19 3TC, D4T NVP M184V G190A D121Y, K122E, D123G, S162A, K173T, Q174K, D177E, Q207A, R211N  
26 TCHAD-26 3TC, D4T NVP M184V K103N K49R, K122E, D123T, T139A, S162C, K173A, D177E, T200E, I202V, Q207K  
28 TCHAD-28 3TC, D4T NVP M184V K103N, V108I K82R, D121H, K122E, S162C, K173S, Q174K, D177E, I178L, T200A, Q207D, R211K, L228Q  
30 TCHAD-30 3TC, D4T NVP   K49R, E53D, V60I, K122A, D123N, D177E, I178L, T200A, Q207E, R211K, F214L  
33 TCHAD-33 3TC, D4T None M184V  D123N, I135V, Q174K, D177E, T200A, I202V, Q207D, R211K, F214L  
35 TCHAD-35 3TC, D4T NVP   K43E, D121H, K122E, D123S, K173A, Q174K, D177E, Q207A, R211S, K238R  
39 TCHAD-39 3TC, D4T None  V106I K49R, V60I, K122E, D123N, S162C, D177E, I178L, Q207E, R211K, F214L  
TCHAD-4 3TC, D4T NVP   E53D, D123E, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207D  
40 TCHAD-40 3TC, D4T NVP  V106I V60I, K122E, D123E, I135V, S162C, Q174H, D177E, T200I, Q207E, R211K, K223R  
47 TCHAD-47 3TC, D4T NVP M184V K103N, G190A K101Q, K122E, D123N, S162T, Q174N, D177E, T200E, Q207K  
48 TCHAD-48 3TC, D4T None M184V  V60I, D123E, I135L, K173Q, Q174K, D177E, I195L, T200A, Q207E, R211K  
53 TCHAD-53 3TC, D4T NVP  Y181C A98S, K122E, D123S, S134R, Y144F, V148G, S162C, K173R, Q174K, D177E, I178L, T200A, E203D, Q207E, R211S I135G 
54 TCHAD-54 3TC, D4T NVP M184V K103N A98S, D123S, I135V, T139R, S162C, K173R, Q174K, D177E, I178L, T200A, E203D, Q207E, R211S  
58 TCHAD-58 3TC, D4T NVP M184V K103S, G190A K122E, D123N, S162F, Q174H, D177E, T200E, I202V, Q207E, R211K L109P 
59 TCHAD-59 3TC, D4T NVP   D123E, I142V, E169A, K173A, Q174K, D177E, Q207A, R211K  
64 TCHAD-64 3TC, D4T NVP M184V A98G, K103N K49R, I135M, S162A, K173T, Q174K, D177E, T200A, Q207E  
66 TCHAD-66 3TC, D4T NVP   K122E, D123G, I135T, K173T, D177E, T200E, I202V, Q207E  
67 TCHAD-67 3TC, D4T NVP D67N, M184V, T215F K101E, G190S K43E, D121H, K122E, D123S, I135T, K173A, Q174K, D177E, V179I, T200A, Q207A, R211S, K238R  
68 TCHAD-68 3TC, D4T None   K49R, V60I, V118I, I135T, I142T, R172K, D177E, I178L, Q207E, F214L  
69 TCHAD-69 3TC, D4T NVP M184V Y181C V60I, A98S, K101R, D121H, K122E, E169D, Q174E, D177E, T200A, Q207E  
70 TCHAD-70 3TC, D4T None M184V  K122E, I135T, S162C, Q174N, D177E, I178L, T200K, I202V, Q207E  
71 TCHAD-71 3TC, D4T NVP   K49R, V60I, K122E, I135T, D177E, I178V, Q197E, T200A, E204K, Q207E, F214L  
72 TCHAD-72 3TC, D4T NVP   K122E, D123N, I135T, S162C, Q174H, D177E, T200E, I202V, Q207N, R211K  
74 TCHAD-74 3TC, D4T NVP M184I K103N, Y181C K49R, V60I, D123E, E169D, K173A, Q174K, D177E, I178M, G196E, Q207E, R211K  
75 TCHAD-75 3TC, D4T NVP M184V, T215F V108I, Y181C K49R, V60I, V90I, I135T, S162H, K173T, Q174K, T200A, Q207E  
76 TCHAD-76 3TC, D4T NVP   K49R, V60I, K122E, D123S, S162C, Q174D, D177E, I178M, G196E, T200E, Q207K  
78 TCHAD-78 3TC, D4T None   K122E, D123N, I135V, S162C, K173T, Q174R, D177E, I178L, T200A, Q207N, R211K  
TCHAD-8 3TC, D4T None D67N, K70R, M184V, K219E V106I V60I, V118I, T139S, T165I, D177E, I178L, K201R, E204K, Q207E, R211K, F214L  
80 TCHAD-80 3TC, D4T NVP   K49R, V60I, R83G, E89K, K104R, K122E, D123N, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E L92T 
85 TCHAD-85 3TC, D4T NVP M184I K103N, Y181C K49R, V60I, D123E, E169D, K173A, Q174K, D177E, I178M, G196E, Q207E, R211K