Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Land (2008)
Title Full-length HIV type 1 proviral sequencing of 10 highly exposed women from Nairobi, Kenya reveals a high proportion of intersubtype recombinants.
Citation ARHR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 10
NumPts 10
Subtype A, D, C + D, G + Unknown

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
ML1076 ML1076 None None   V35T, V60I, K64KR, D123E, D177E, T200A, Q207E, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, G335D, P345Q, F346Y, R356K, G359T, T377Q, S379C, K390R, A400T, E404D, V435M, L469I, H483N, L491S, S519N, K530R, A534S, A554S  
ML1901 ML1901 None None   K11T, V35T, K122E, D123G, I135T, I142V, K173L, Q174K, D177E, V179I, Q207A, R211S, V245E, D250E, S251N, K281R, T286A, E291D, V292I, I293V, E312N, G335D, M357K, G359S, A360T, A371V, I375V, A376T, A400T, T403M, E404D, W410C, V417I, E432D, V458I, D471E, Q480H, L491S, K512R, E514D, S519N, Q524K, K527G, E529D, A534S, A554S  
ML1945 ML1945 None None   E6S, K11T, V21I, V35T, T39G, K122E, D123N, S162A, K173LS, D177E, V179I, T200A, I202V, Q207A, R211S, V245Q, E248D, T286A, K287R, E291D, I293V, P294T, K311R, E312H, G335D, M357K, G359S, K366R, T369A, A371AT, I375V, A376V, T377M, T386A, E396D, A400T, T403M, E404D, E432D, V435Q, L452IV, T470TA, D471E, Q480H, L491S, K512R, L517I, S519N, Q524K, K527E, E529D, A534S, A554S, V559I  
ML1956 ML1956 None None   V35T, T39A, I135R, I142V, D177E, I178M, T200I, Q207E, R211K, K238R, V245K, D250E, A272P, K277R, L282C, L283I, V292I, I293V, P321Q, G335D, F346L, R356K, G359T, T377Q, S379C, K385R, K390R, E399D, A400T, E413ED, V435IM, L469I, H483N, L491S, A534S, A554S  
ML1974 ML1974 None None   K11Q, K20R, V35T, T39M, V60I, D121H, K122E, D123S, I135T, K173S, Q174K, D177E, V179I, Q197E, T200A, Q207A, R211S, V245M, E248D, T286A, E291D, I293V, P294T, E312D, G335D, M357Q, R358K, G359S, A371V, I375V, A376V, T377L, T386I, K390R, A400T, T403M, E404D, E432D, V467I, D471E, Q480H, L491S, K512R, S519N, Q524K, K527G, E529D, A534S, A554S  
ML1979 ML1979 None None   V35T, T39A, K122E, D123S, A158S, K173R, Q174E, D177E, I178M, T200A, Q207K, R211N, V245Q, D250E, K281R, T286A, E291D, V292I, I293V, P294T, E312N, G335D, R356K, M357G, R358G, G359S, E370A, A371V, T386I, A400T, T403M, E404D, E432D, V435A, D471E, Q480H, H483Q, L491S, K512R, L517I, S519N, K527R, A534S, A554S  
ML1990 ML1990 None None   V35T, E40D, K49R, V60I, K122E, D123S, I135T, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, V245Q, D250E, E291D, V292I, I293V, P294T, E312D, I326M, G335D, M357K, G359S, K366R, T369A, A371V, I375V, A376V, T377M, A400T, E404D, E432D, V435A, D471E, Q480H, L491S, S519N, Q524K, K527E, E529D, A534S, A554K  
ML2000 ML2000 None None   V35T, E40D, K49R, V60I, K104KR, K122E, D177E, I178M, T200I, Q207EG, R211K, D250E, A272P, L282C, I293V, K311R, G335D, P345Q, F346H, R356K, M357T, A360T, T377L, S379C, K390R, A400T, H483K, L491S, S519N, Q524E, A534S, A554S  
ML2014 ML2014 None None   V35T, E40D, K49R, V60I, D121H, K122E, I135T, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, V245Q, K249R, D250E, I257IV, T286A, E291ED, I293IV, P294T, E312DH, G335D, M357K, G359S, A360AT, K366R, A371V, I375V, A376V, T377M, A400T, T403M, E404D, E432D, V435E, F440Y, S468T, D471E, T477A, Q480H, L491S, K512R, S519N, Q524K, K527G, E529D, A534S, A554S, V559I  
ML752 ML752 None None  V106I V35T, V60I, K122E, D123G, I135T, K173S, Q174K, D177E, V179I, Q207A, R211S, V245M, D250E, T286A, E291D, V292I, I293V, E312D, G335D, M357R, G359S, T369A, A371V, I375V, A376V, A400T, T403M, E404D, E432D, V435A, V467I, D471E, Q480H, L491S, S519N, Q524K, K527G, E529D, A534S, A554S  

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