Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Hombrouck (2008)
Title Mutations in human immunodeficiency virus type 1 integrase confer resistance to the naphthyridine L-870,810 and cross-resistance to the clinical trial drug GS-9137.
Citation AAC
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
SelectedType Lab
NumIsolates 3
Lab Parent Strain NL43


Lab IN Isolates : Susceptibility Data

IsolateINIMajorDRMsINIMinorDRMsMethodDrugFold Res.
E92Q E92Q  Antivirogram EVG 17 
     Antivirogram L870-810 18 
     Antivirogram RAL 3.0 
L74M   Antivirogram EVG 0.7 
    Antivirogram L870-810 1.2 
    Antivirogram RAL 1.2 
S230N   Antivirogram EVG 1.2 
    Antivirogram L870-810 1.8 
    Antivirogram RAL 1.7