Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author de Sa Filho (2008)
Title HIV type 1 poltype 1 pol gene diversity and antiretroviral drug resistance mutations in Santos, Brazil.
Citation ARHR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 83
NumPts 83
Subtype B, F, C

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
2249 BRLUS2249 NRTI, TDF, 3TC EFV K65R, M184V K103N, V108I, F227FL, K238KT K20R, S68X, I135T, I142IV, E169D, D177E, G196E, Q197L, T200E, I202V, E203K, K223KT  
2250 BRLUS2250 NRTI, AZT, 3TC EFV M41L, L74V, M184V, T215Y L100I, K103N T27S, K102R, I135V, I142V, R211K Y115YH, D256DN 
2251 BRLUS2251 NRTI, AZT, 3TC NVP M41ML, M184V, L210LW, T215Y K103N, E138A, K238KT P4PS, K20R, V60I, I135L, I142T, K166R, E248N  
2256 BRLUS2256 NRTI, D4T, DDI NNRTI M41L, D67E, L210W, T215Y  V35I, T39A, K43Q, E44D, V60I, S68G, V118I, I135T, D177E, G196E, T200A, E203K, R211K, F214L, V245I, V261G, K263E  
2258 BRLUS2258 NRTI, AZT, D4T, DDI NNRTI   K122E, D123DE, I135T, S162C, N175H, Q207E, R211RK  
2259 BRLUS2259 NRTI, AZT, 3TC NNRTI M41L, V75M, M184V, T215F K103NS P4S, T39A, V90I, K122E, I142V, T200A, Q207E, R211RK, V245T  
2306 BRLUS2306 NRTI, 3TC, D4T NNRTI M184V  K11KR, V35I, V60I, D121Y, K122E, F124FL, I135T, I142V, G196E, Q197P, T200TI, V245E  
2307 BRLUS2307 NRTI, TDF, 3TC NNRTI M41L, D67N, T69D, M184V, L210W, T215Y V108I, V179E, G190A P4S, E44D, K103R, V118I, D121Y, K122E, I135T, V189I, E203D, R211K, E224D, L228H, V245Q  
2326 BRLUS2326 NRTI, 3TC, D4T NNRTI A62V, K65R, V75I, F77L, Y115F, F116Y, Q151M, M184V, K219Q  V35I, T39A, K49R, S68G, T69I, V118I, K122E, I135T, S163C, T165I, E169D, T200A, I202V, F214L, V245K  
2327 BRLUS2327 NRTI, TDF NNRTI M41L, D67N, K70R, V75VIM, M184V, T215Y, K219E Y188L T39A, V60I, S68G, I94L, K122E, I135T, V179I, T200A, R211RK, D218E, L228LH, V245M  
2328 BRLUS2328 NRTI, 3TC, D4T NNRTI M41L, D67N, T69D, M184V, L210W, T215Y  V35L, E44D, A98S, V118I, D121H, K122E, I135IT, S162D, D177E, V179I, T200A, I202V  
2329 BRLUS2329 NRTI, AZT, 3TC NNRTI M41L, M184V, L210W, T215Y A98G T39TA, S68SG, K102Q, V118VI, K122E, I135IV, T200A, R211K, E248N  
2330 BRLUS2330 NRTI, TDF, 3TC NNRTI D67N, K70R, M184V, T215Y, K219E Y181C, G190A K20R, V60I, T69TN, K122E, I135T, K173R, V179I, T200V, R211K, F214L, L228H  
2331 BRLUS2331 NRTI, AZT, 3TC EFV M41L, M184V, L210LW, T215Y A98G, K101E, Y181C, G190A, H221HY K32KE, I135T, L228LM, D237DE, V245VM, D256E  
2356 BRLUS2356 NRTI, AZT, 3TC NNRTI M41L, M184V, L210W, T215Y K103N, E138EQ T39E, E44D, K49R, V60I, S68G, V118VI, K122E, I135T, T139R, S162C, E169R, K173E, T200A, R211K, V245VM T240TIM 
2357 BRLUS2357 NRTI, ABC, 3TC EFV M41L, L74V, M184V, T215Y L100I, K103N, E138EQ, P225H K102Q, K122E, D123E, I135T, S163C, V179I, T200A, V245T, E248ED  
2358 BRLUS2358 NRTI, AZT, 3TC NNRTI M41L, D67DN, M184V, L210W, T215Y  K20R, T39A, T69X, K82KR, A98AS, K122E, R211K  
2359 BRLUS2359 NRTI, AZT, 3TC NVP M184V, T215Y K103N, K238KT K20R, I135T, I142T, S162C, E169A, K173A, Q174K, T200E, E203Q, Q207D, R211K, V245Q, E248D  
2364 BRLUS2364 NRTI, AZT, 3TC NNRTI M41L, D67N, T69D, M184V, L210W, T215Y  K43KN, E44ED, K102KR, V118VI, I135T, I142IV, G196GE, R211K, V245T, D250E  
2366 BRLUS2366 NRTI, 3TC, D4T EFV M41L, M184V, L210W, T215Y K103N, V108I, K238T K20R, K122E, D123E, I135T, D177E, I178M, V189VI, T200K, R211K  
2367 BRLUS2367 NRTI, 3TC, D4T NNRTI M184V K103N E6D, K20R, V35T, T69TA, I135V, I142IV, S162C, E169D, K173A, Q174K, I178L, T200A, Q207E, R211K, V245Q, E248D, D250DE, S251N  
2368 BRLUS2368 NRTI, 3TC, D4T NVP M184V K103N K49KR, D123E, I135L, I178IM, V179I, R211K, K259KR  
2389 BRLUS2389 NRTI, AZT, DDI EFV M41ML, L210W, T215Y K103N, V108I K43KE, S48T, K49R, V118I, K122E, D123E, I135T, E169D  
2390 BRLUS2390 NRTI, AZT, DDI NNRTI   K20KR, K32R, K49R, I135IT, T165I, R211K, V245MT, E248ED  
2409 BRLUS2409 NRTI, 3TC, D4T NNRTI M41L, D67G, L74LI, M184I, T215Y L100I, K103N E6D, K11KR, K20R, T69TN, V90I, K122E, I135IV, I142V, D177E, V179I, T200TA, I202V, E224D  
2410 BRLUS2410 NRTI, 3TC, D4T EFV M41L, L74V, M184V, T215F G190Q K20R, K43KE, V118I, K122E, I135T, S162A, V189I, T200A, R211K, V245E  
2411 BRLUS2411 NRTI, AZT, 3TC EFV M41L, L74I, V75M, M184V, L210W, T215Y K103N, P225H T39A, E44D, A98S, V118VI, K122E, I135L, K166R, V189I, I202V, R211K, V245M K43PT 
2412 BRLUS2412 NRTI, AZT, 3TC EFV M41L, A62V, L74V, V75T, M184V, L210W, T215Y L100I, K103N K20R, K43Q, K102Q, D123E, I135T, V179T, G196E, T200A, I202V, E203K, E204D, R211A, K223KE, L228R V111VIM 
2419 BRLUS2419 NRTI, AZT, 3TC NVP M41L, M184V, L210W, T215Y K103N, K238T K20R, K43Q, K122E, D123DN, I135T, K166R, G196E, R211K, V245K  
2420 BRLUS2420 NRTI, 3TC, D4T NVP D67N, K70R, M184V, T215FV, K219Q A98AG V60I, T69N, V118I, K122E, D123EK, I135T, I142IV, F214L, D218E  
2421 BRLUS2421 NRTI, AZT, 3TC NNRTI M41L, M184V, L210W, T215Y K101H K20R, T39S, A98S, K122E, Q174K, T200A, R211RK  
2422 BRLUS2422 NRTI, AZT, 3TC NNRTI M41L, M184V, L210W, T215Y  T39A, V118VI, D123E, I135T, I142V, S162X, I178L, G196E, Q197L, R211K  
2423 BRLUS2423 NRTI, D4T, DDI NNRTI M41L, D67N, T69DN, K70R, L74LI, M184V, T215F, K219E Y188L K11KR, V35VL, V60I, K102M, L109LV, V118VI, I135T, S162C, T200I, Q207A, H208HY, R211K, L228H, V245EK  
2426 BRLUS2426 NRTI, 3TC, D4T NNRTI F116Y, Q151M, M184V  P4PS, K20R, V35I, S68G, K102Q, D123E, I135T, S162Y, D177E, R211G, F214L, V245Q, I257L  
2430 BRLUS2430 NRTI, AZT, 3TC NNRTI M184V  V35I, R83K, T107S, K122E, D123DG, Q174K, V179VI, T200A, R211K, F214FL  
2436 BRLUS2436 NRTI, 3TC, D4T NNRTI D67N, T69D, K70R, M184V, K219Q  V35I, V60I, V118VI, I135T, K173T, Q174K, N175Y, G196E, T200A, E203K, Q207E, R211RK, F214FL, V245Q  
2437 BRLUS2437 NRTI, 3TC, D4T NNRTI M184V  V35T, E36A, T39DE, S48ST, K122E, D123S, I135RT, K173T, Q174K, T200A, Q207E, R211K, F214L, V245Q  
2445 BRLUS2445 NRTI, AZT, 3TC EFV M41ML, M184V, T215Y K103KN, G190A R83K, V90I, K101X, K122E, D123DN, E138S, S162X, Q174N, T200A  
2446 BRLUS2446 NRTI, AZT, 3TC EFV M184V K101E, G190A R211K, V245M  
2447 BRLUS2447 NRTI, TDF, 3TC EFV K65KR, L74LI, M184V K101P, K103N K20R, E28EK, K32KE, V35VI, K49R, S68SN, K70X, E169D, K173A, Q174K, Q197E, Q207E, H208HY, R211K, V245Q, E248N  
2449 BRLUS2449 NRTI, 3TC, D4T NVP M41L, M184V, T215Y A98G, K103N, Y181YC, K238T T7TA, K32R, T39TA, I135T, I142V, D177E, G196E, L228LH  
2460 BRLUS2460 NRTI, AZT, 3TC NNRTI M41L, V75M, M184V, L210W, T215Y  E44D, K64H, V118I, D121DH, K122E, I135T, K166R, T200A, I202V, L228R  
2461 BRLUS2461 NRTI, AZT, 3TC EFV M184V, T215Y A98G, K103NS, G190A E6D, I135L, K173A, Q174K, T200A, E203D, Q207E, V245Q, E248N  
2506 BRLUS2506 NRTI, AZT, 3TC EFV D67N, K70R, M184V, K219Q K103N K20R, V35I, E44D, I135T, T200A, E203D, F214L, V245I  
2508 BRLUS2508 NRTI, AZT, 3TC NVP M41L, M184V, T215Y K103N, E138Q K20R, K43KQ, V60I, D123E, I135T, D177E, T200A, V245LQ  
2509 BRLUS2509 NRTI, AZT, 3TC EFV  K103N K20R, K101R, K102KQ, I135T, F214FL  
2515 BRLUS2515 NRTI, AZT, 3TC NNRTI   E6D, K20R, V35M, T165TI, E169ED, T200I  
2516 BRLUS2516 NRTI, AZT, 3TC NNRTI M41L, D67N, M184V, L210W, T215Y, K219N  T39A, K43KE, E44D, V118I, K122E, I135T, S162Y, D177DG, V179I, H208Y, R211K, K223Q, P243PS, V245M P9K 
2517 BRLUS2517 NRTI, TDF, 3TC EFV D67N, K70R, V75M, F77L, M184V, K219Q K103N, H221Y, P225H K20R, V35VL, K101R, K122E, D123E, I135T, T200I, I202V, V245T  
2518 BRLUS2518 NRTI, 3TC, D4T NNRTI D67N, K70R, M184V, K219Q  E28K, V35T, V60VI, K122E, D123E, I135V, S162Y, E169AD, K173R, Q174KR, N175NY, G196E, T200TA, V245K  
2555 BRLUS2555 NRTI, AZT, 3TC NVP M184MV K103N, K238T K20R, S68SG, I135T, T200A, R211K, T215X, V245K  
2561 BRLUS2561 NRTI, AZT, 3TC EFV K65R, K70R, V75I, F77L, Y115F, F116Y, Q151M, M184MV, K219E K103N, Y181C, G190A V35M, S68G, V90I, K101R, V111VI, K122E, D123N, T165I, T200A, I202V, V245T  
2562 BRLUS2562 NRTI, TDF, 3TC NVP M184V, T215F Y181C, H221Y K20R, E53D, I135T, T165L, Q174QH, Q207E, R211K, D250E  
2575 BRLUS2575 NRTI, AZT, 3TC EFV M184V, T215F K103N I31L, V35KT, T39D, I135T, I142T, R211K, V245E  
2583 BRLUS2583 NRTI, TDF, 3TC NNRTI M41L, D67N, K70R, L74I, M184V, T215F, K219E  T39A, K49R, T69N, D121DY, K122E, I135T, S162C, V179I, H208Y, D218E, L228H, V245M  
2584 BRLUS2584 NRTI, TDF, AZT, 3TC NNRTI M41ML, M184V, T215F K103N, E138EQ, K238KT K20R, A98S, I135IT, T200A, V245E  
2585 BRLUS2585 NRTI, AZT, 3TC NNRTI K65KR, D67DN, K70KR, K219KQ K103KN S68SG, K102KR, K122KE, D123DE, I135T, I178L, V245M  
2586 BRLUS2586 NRTI, AZT, 3TC EFV D67N, K70KR, M184V, T215TI, K219EQ K103N, G190A V35I, K122E, D123E, I135IMT, I178M, T200E, E204R, Q207E, V245VE  
2587 BRLUS2587 NRTI, AZT, 3TC NVP D67N, K70R, M184V, T215F, K219Q K101KE, K103N, V106I E28EK, A98AS, V118I, I135T, I202V, R211K, F214L  
2588 BRLUS2588 NRTI, AZT, 3TC NVP M184V K103N, K238KT K122E, D123DN, I135T, I142V, T200A, V245IRT  
2589 BRLUS2589 NRTI, 3TC, D4T NNRTI M184V M230ML I31IL, K66KR, A98S, K122E, D123E, S162C, I195L, L228H  
2609 BRLUS2609 NRTI, TDF, 3TC, DDI EFV M41L, L74V, M184V, T215Y A98G, L100I, K103N V35L, T39A, S68G, K122E, I135T  
2610 BRLUS2610 NRTI, TDF, 3TC, D4T NNRTI M41L, D67G, K70R, M184V, T215F, K219Q K103N, G190A E6D, K20R, T69N, A98S, K102N, K122E, D123N, I135L, L228H, V245E  
2627 BRLUS2627 NRTI, AZT, 3TC EFV M41L, D67DN, M184V, L210W, T215Y A98G K20R, V35L, T39AS, V118I, I135L, T139TM, S162C, E169D, K173A, Q174K, Q207E, R211K, L228LH, V245Q, E248D  
2628 BRLUS2628 NRTI, 3TC, D4T NVP K70KR, M184V V106I, Y188L K20R, V90VI, D123E, S162Y, E169D, D177E, V179I, I180IV, R211K, F214L, E224D  
2629 BRLUS2629 NRTI, AZT, 3TC NVP M41L, M184V, T215Y K103N E28A, V90VI, K101KQ, K122E, D123E, I135T, S162Y, T200TK, Q207E  
2630 BRLUS2630 NRTI, AZT, 3TC NNRTI M41L, V75M, F77L, M184V, L210W, T215Y E138A T39TA, K64KR, I135T, D177N, I178L, G196E, T200A, V245Q  
2635 BRLUS2635 NRTI, 3TC, D4T NNRTI M41L, D67N, K70R, M184V, L210W, T215Y, K219E  V35IT, T39TA, E53D, T69N, V118I, K122E, D123E, I135T, K166R, V179I, G196E, R211K, F214FL, L228H  
2636 BRLUS2636 NRTI, AZT NNRTI D67N, K70R, M184V, T215V, K219Q  K11T, K20R, D121H, K122E, D123S, I135T, V179I, I202V, R211K, F214L, V245T  
2638 BRLUS2638 NRTI, AZT, 3TC EFV M184V K103N, V108VI, P225PH V35M, T39A, R83K, A98AS, D121HY, K122E, I135T, K166KR, D177E, G196E, Q207QH, R211K  
2645 BRLUS2645 NRTI, TDF, 3TC, DDI NNRTI M41L, D67N, V75M, M184V, T215F, K219N L100I, K103N K22KR, V35VL, T39A, E44D, V60I, I94IL, V118I, I135T, T139TR, I159IL, V179I, T200TA, F214L, V245K  
2680 BRLUS2680 NRTI, 3TC, D4T NVP K70R, M184V K103N T69S, D123DE, I135L, K173KEQ, Q174QR, I178L, T200A  
2693 BRLUS2693 NRTI, AZT, 3TC NVP M184V K103N E6EK, K20R, K122E, I135T, I142IV, G196E, D237E, V245M  
2694 BRLUS2694 NRTI, AZT, 3TC NNRTI M41L, D67N, K70R, V75M, F77L, M184V, T215F, K219Q A98AG, K103N T39A, K82R, V118I, K122E, T139Q, G196E, Q197K, R211K, F214L, L228H  
2701 BRLUS2701 NRTI, AZT, 3TC NNRTI M41L, M184V, T215Y  V60I, S68G, K122KE, I135T, D177EG, T200A, R211KT, F214FL, V245VI  
2702 BRLUS2702 NRTI, 3TC, D4T NNRTI M41L, K70KR, L74LI, M184V, L210L*W, T215FY  V35M, K43KE, D67X, S68SG, K104KR, V118VI, K122KE, D123X, S162SC, E169ED, V179I, T200A, I202V, R211K, K219X, E224EK  
2703 BRLUS2703 NRTI, 3TC, D4T NNRTI T69D, K70R, M184V, T215I, K219Q L100I, K103N V111VI, D121Y, K122E, I135T, T200A, F214L, L228R, V245K, K249KR  
2704 BRLUS2704 NRTI, 3TC, D4T NNRTI M41L, M184V, L210W, T215Y  K20R, T39A, D123DE, I135T, S162C, V179VI, T200A, R211RK, E224D, P243H  
2705 BRLUS2705 NRTI, 3TC, D4T NVP D67N, K70R, T215FV, K219Q V108I, Y181C, H221Y K20KR, L34I, V35T, E40D, V60I, V90I, A98AS, K101KQ, S162Y, E169D, K173A, Q174K, V179I, I202IV, Q207A, R211K, K223KT, L228HR, V245Q, E248D  
2706 BRLUS2706 NRTI, AZT, 3TC NVP M184V K103N, Y181C E28EG, V35L, E169D, T200A, Q207T H208S 
2707 BRLUS2707 NRTI, AZT, 3TC NNRTI M41L, D67N, L74V, M184V, L210W, T215Y, K219R V106M, V179D, F227L K20R, T39A, E44D, T107S, V118I, K122E, I135T, I202V, E203K, H208Y, K223E, L228H, V245T  
2732 BRLUS2732 NRTI, AZT, 3TC NVP M184V K103N K122KE, I135T, I142V, S162C, D177E, I178L, Q197QH, T200A, D218DE  
2743 BRLUS2743 NRTI, TDF, AZT, 3TC NNRTI M41L, M184V, L210W, T215Y K103N, V108I, K238KT S3SC, V35IT, V60VI, V90VI, K102KQ, D123E, I135T, S162N, I178IM, D192N, T200K, K223Q, L228LR, I244IV  

Database

Resources

Team